• 제목/요약/키워드: functional domain

검색결과 533건 처리시간 0.024초

ON THE STABILITY OF A BI-JENSEN FUNCTIONAL EQUATION

  • Jun, Kil-Woung;Lee, Yang-Hi;Oh, Jeong-Ha
    • 한국수학교육학회지시리즈B:순수및응용수학
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    • 제17권3호
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    • pp.231-247
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    • 2010
  • In this paper, we investigate the generalized Hyers-Ulam stability of a bi-Jensen functional equation $4f(\frac{x\;+\;y}{2},\;\frac{z\;+\;w}{2})$ = f(x, z) + f(x, w) + f(y, z) + f(y, w). Also, we establish improved results for the stability of a bi-Jensen equation on the punctured domain.

ON THE GENERALIZED HYERS-ULAM STABILITY OF A BI-JENSEN FUNCTIONAL EQUATION

  • Jun, Kil-Woung;Lee, Ju-Ri;Lee, Yang-Hi
    • 충청수학회지
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    • 제22권3호
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    • pp.383-398
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    • 2009
  • In this paper, we study the generalized Hyers-Ulam stability of a bi-Jensen functional equation $$4f(\frac{x+y}{2},\;\frac{z+w}{2})=f(x,\;z)+f(x,w)+f(y,\;z)+f(y,w)$$. Moreover, we establish stability results on the punctured domain.

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다양한 함수를 이용한 확장성 있는 데이터 가시화 (Scalable Data Visualization with Various Functional Representations)

  • 장윤
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2012년도 한국컴퓨터종합학술대회논문집 Vol.39 No.1(C)
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    • pp.413-414
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    • 2012
  • Currently the amount and variety of data being generated is unprecedented and dramatically changes the way individuals, groups, and societies act and make decisions. Visualization is one of the most important commonly used methods of analyzing and interpreting digital assets and the interactive environments are necessary to enable effective discovery and decision making. In this paper we present several examples and approaches to scalable functional representations and interactive visualization and analysis. The functional representations provide us unified, compact, continuous, multi-scale, and compressed representations in the data domain.

MODIFIED LAGRANGE FUNCTIONAL FOR SOLVING ELASTIC PROBLEM WITH A CRACK IN CONTINUUM MECHANICS

  • Namm, Robert V.;Tsoy, Georgiy I.;Woo, Gyungsoo
    • 대한수학회논문집
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    • 제34권4호
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    • pp.1353-1364
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    • 2019
  • Modified Lagrange functional for solving an elastic problem with a crack is considered. Two formulations of a crack problem are investigated. The first formulation concerns a problem where a crack extending to the outer boundary of the domain. In the second formulation, we consider a problem with an internal crack. Duality ratio is established for initial and dual problem in both cases.

Soluble Expression and Purification of Human Tissue-type Plasminogen Activator Protease Domain

  • Lee, Hak-Joo;Im, Ha-Na
    • Bulletin of the Korean Chemical Society
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    • 제31권9호
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    • pp.2607-2612
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    • 2010
  • Human tissue-type plasminogen activator (tPA) is a valuable thrombolytic agent used to successfully treat acute myocardial infarction, thromboembolic stroke, peripheral arterial occlusion, and venous thromboembolism. Recombinant tPA is accumulated as an inactive form in inclusion bodies of E. coli and is refolded in vitro, which is accompanied by extensive aggregation. In the present study, a tPA protease domain was expressed in an active soluble form in the cytosol of E. coli Rosetta-gami cells, which allowed disulfide bond formation and supplied the tRNA molecules required for six rarely used codons in E. coli. This strategy increased the amount of soluble protease domain protein and avoided the cumbersome refolding process. The purified protease domain not only degraded tPA substrate peptides but also formed a covalently bound complex with plasminogen activator inhibitor-1, as does full-length tPA. Soluble expression and purification of tPA domains may aid in functional analyses of this multi-domain protein, which has been implicated in many physiological and pathological processes.

Frequency Domain Analysis of Lifting Problems with Explicit Kutta Condition

  • Kim, Jong-Un;Kim, Gun-Do;Lee, Chang-Sup
    • Journal of Ship and Ocean Technology
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    • 제7권3호
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    • pp.34-55
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    • 2003
  • Explicit Kutta condition approximation, proved useful in existing time-domain solver of the unsteady propeller problem, requires a specified functional behavior of the vorticity in space near the trailing edge. In this paper, the strength of the discrete vortices is controlled to have a specified behavior in space in the frequency domain approach. A new formulation is introduced and is implemented for analysis of a lifting surface of a rectangular planform. Sample computations carried out according to the new formulation compares well with that of existing unsteady lifting problem in the time domain.

Expression and Biochemical Characterization of the Periplasmic Domain of Bacterial Outer Membrane Porin TdeA

  • Kim, Seul-Ki;Yum, Soo-Hwan;Jo, Wol-Soon;Lee, Bok-Luel;Jeong, Min-Ho;Ha, Nam-Chul
    • Journal of Microbiology and Biotechnology
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    • 제18권5호
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    • pp.845-851
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    • 2008
  • TolC is an outer membrane porin protein and an essential component of drug efflux and type-I secretion systems in Gram-negative bacteria. TolC comprises a periplasmic $\alpha$-helical barrel domain and a membrane-embedded $\beta$-barrel domain. TdeA, a functional and structural homolog of TolC, is required for toxin and drug export in the pathogenic oral bacterium Actinobacillus actinomycetemcomitans. Here, we report the expression of the periplasmic domain of TdeA as a soluble protein by substitution of the membrane-embedded domain with short linkers, which enabled us to purify the protein in the absence of detergent. We confirmed the structural integrity of the TdeA periplasmic domain by size-exclusion chromatography, circular dichroism spectroscopy, and electron microscopy, which together showed that the periplasmic domain of the TolC protein family fold correctly on its own. We further demonstrated that the periplasmic domain of TdeA interacts with peptidoglycans of the bacterial cell wall, which supports the idea that completely folded TolC family proteins traverse the peptidoglycan layer to interact with inner membrane transporters.