• Toxicological Research
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• v.17
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• pp.329-333
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• 2001

Apoptosis is the normal physiological process of cell death essential for the maintenance of homeostasis. The function of nicotinamide adenine dinucleotide (NAD) and adenine diphosphate (ADP) ribosylation (transfer of ADP-ribose to proteins) reactions in modifying apoptosis have recently been of great interest. Recently. CD38. a type 2 transmembrane glycoprotein expressed in hematopoietic and non hematopoietic cell lines. has been reported to possess NAD glycohydrolase activity (Han. 1999) and PC-1 and CD38 NADase regulates T cells by inhibition of phosphodiesterase/pyrophosphatase activity of PC-1 by its association with glycosaminoglycan (Hozada et al., 1999). Sindhuphak et al. (2000) has reported that cervical cancer cells can be differentiated from normal cells by using FTIR (Fourier-Transformed Infrared) technique. which has characterized shifts to be due to the phosphodiester bond in nucleic acid. protein amide I&II. carbohydrate and glycogen bands. Mechanisms how phosphodiester bond shift in cervical cancer cells as compared to control cells remain to be elucidated. Suramana et al. (2000) as well as Lohitnavy and Sinhaseni (1998) have studied methomyl and colchicine effects in rat splenocytes. Lactate Dehydroge-nase Isozymes 3 (LDH3) and LDH4 were observed to increase transiently and subsided in plasma of rats exposed to 6~8 mg/kg methomyl after 48 hours. Phosphodiester bond shift of nucleic acid. detected by FTIR. was also reported (Suramana et al., 2000). We report here, after analysis of bond shift patterns. a similar bond shifts detected by FTIR spectrum observed in human cervical cells and splenocytes of rats exposed orally to 2~8 mg/kg methomyl as well as rats exposed to colchicine 2~6 mg/kg orally.

• Korean Journal of Food Science and Technology
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• v.31 no.1
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• pp.164-170
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• 1999

Cracking of rice caused by moisture migration during storage under different relative humidity conditions was investigated for the establishment of safe storage condition of rice. Rice was cracked when a large difference in equilibrium relative humidity $({\Delta}ERH)$ between the rice and the environment was present. External and internal cracks were generated as the results of moisture desorption and adsorption, respectively. The external cracks by moisture desorption generated in all directions and shaped irregularly, while the internal cracks by moisture adsorption did in radial direction and showed a typical shape. The cracking trend could be analyzed by the Weibull function, and the cracking constant increased with ${\Delta}ERH$. The frequency of cracked rice increased linearly with In $({\Delta}ERH)$. The critical crack-inducing ${\Delta}ERH$ was $11.3{\sim}16.4%$ during desorption and $10.8{\sim}17.1%$ during adsorption. A diagram for the safe storage of rice was developed with respect to the initial moisture content and the water activity of rice.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.7 s.155
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• pp.1090-1102
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• 2006

The purpose of this study is to develop an improved work clothing which is much safe, comfortable, mobility and convenient than what workers currently wear at construction site. The investigation has been conducted to evaluate current work clothing to grasp any problems, discomforts and damages related to the work clothing. For the best and accurate data, hands-on investigation and a short-interview have been performed at the construction site as well as formulating a questionnaire. The questionnaires was answered by 425 workers and safety manager of 13 different construction site. The result of the questionnaire enables us to design a sample work clothing, many pa π s such as material, pattern and design have been improved. To improve the amenity of heat, the surface of a material was used by $Aerocool^{\circledR}$ fiber which contains inside dryness function. In order to absorb perspiration on the back the armpits, mesh martial that is mixture of $Coolever^{TM}$ fiber and $Mirawave^{TM}$ fiber was used to absorb perspiration in an effective manner. And a sleeve's bottom part and trousers' bottom part's cover method have been changed. Sample work clothing was shorten at the side of upper garment up to 2cm and lengthen the length of the back by 3cm. To reduce the tightness around armpit more room was given in that area. Darts were added to the elbow, the hip, and the knees that also followed an ergonomic pattern. A sample work clothing evaluated an objective assessment and subjective assessment to compare to a current work clothing. Assessment group consists of seven subject groups and nine expert groups to evaluate external appearance and adaptability to the movements. In all aspects of the test, the result of evaluation process of the sample work clothing received more positive assessment than the current work clothing.

• Journal of the Korean Society for Railway
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• v.10 no.6
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• pp.709-716
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• 2007

An active steering bogie has been theoretically proved to improve both stability and steering performance remarkably. However, It has not been commercialized yet even though many researchers have been trying to develop it because some technical difficulties still exist such as information acquisition fer active control, increasing mechanical components, high energy consumption, fail-safe problem and so on. To solve those problems, an advanced active steering mechanism is proposed in this paper. With this mechanism, required control force is small enough to use direct drives. Therefore, the number of additional mechanical components can be minimized since mechanical transducers like gears are not necessary. Fail-safe function can be also inserted easily. In this paper, concept design of the proposed active steering bogie is introduced and the possibility is verified through computer simulation using linear dynamic model.

• Journal of Digital Contents Society
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• v.19 no.8
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• pp.1507-1514
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• 2018

The purpose of this study was to propose a functional improvement solution of integrated control board for safe driving of Smart electric wheelchair for a single person. In the case of existing electric wheelchair products in Korea and elsewhere, safety-related functions or devices are not included in many cases. Therefore, the incidence of electric wheelchair-related accidents is continuously increasing in the current situation in which the elderly and the disabled people have been continuously increased. However, currently only high and middle-priced products are equipped with basic safety devices in electric wheelchairs, so low-priced products require safety related functions. Therefore, sensing obstacles that the user can not recognize while moving an electric wheelchair and detecting automatically the terrain change to control the motor by developing a smart control platform. This provides an integrated control board that can be applied to various electric wheelchairs for more stable driving.

• Journal of Institute of Control, Robotics and Systems
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• v.20 no.4
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• pp.456-462
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• 2014

In this paper, we present a deployable bio-inspired robot called the Pillbot-light, which utilizes a safe autonomous navigation system. The Pillbot-light is mounted the station robot, and can be operated in a disaster relief operation or military operation. However, the Pilbot-light has a challenge to navigate autonomously because the Pilbot-light cannot be equipped with various sensors. As a result, we propose a new robot system for autonomous navigation that the station robot controls Pillbot-light equipped with vision camera and CPU of high performance. This system detects obstacles based on the edge extraction using vision camera. Also, it cannot only achieve path planning using the hazard cost function, but also localization using the Particle Filter. And this system is verified by simulation and experiment.

• Journal of the Korean Institute of Landscape Architecture
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• v.31 no.4
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• pp.1-12
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• 2003

The urban park provides a safe rest and leisure area, and offers the beauty of nature to counter the drearyness of urban space. It can provide benefits such as the reduction of environmental pollution, the regulation of the local climate, and it can also provide a safe area during times of disaster. However, there was no interest in urban park development and control in Korea during the economic boom of the mid 1960s. Furthermore, during the industrialization process, the population grew significantly in the cities and the cities' scales were noticeably extended; as a result of this, the living environment and the natural environment in the cities worsened. With rapid urbanization and industrialization, urban green area diminished, and it became necessary to organize the urban park system to improve quality of life. 45% of south korea's population lives in 6 cities, which is only 4% of Korea's land size. The Urban park system has to be considered in the urban planning process. Paris' urban green system can be a role-model for Korea's urban green development plan to function organically. Urban public park concepts have been used in Paris's urban planning since 1850. There were hardly any parks, gardens and squares for the public before the middle of the 19th century. For improving life-styles for the poor, Napoleon III strongly supported the development of green space systems in Paris by G.E. Haussmann. Napoleon III and Haussmann established and applied the urban green regulation within Paris urban planning. The purpose of this study is to investigate the green regulations Haussmann's Paris urban plan and urban green space system: and as a result of this, it can be an indicator for urban green space development in Korea.

• Journal of Society of Preventive Korean Medicine
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• v.9 no.1
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• pp.119-133
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• 2005

Traditional herbal medicine is widely used among the Korean people, and other eastern Asian countries employ similar therapies as well. In recent years, due to increasing interest in herbal medicines, many researches have been made on the toxicity and side effects of herbal medications. Through private and public media, there have been many opinions suggesting taking herbal medicines is very harmful, especially on the liver and kidney functions. This assertion has been mainly presented by the doctors that practice western medicine, But this assertion is never based on adequate knowledge of herbal medicine. This study aims to provide the evidences that taking herbal medicines is safe on the renal functions. Four frequently used herbal medications(Sipjeondaebotang, Bojungigitang, Ojeoksan, and Yukmijihwangtang) were used to test the toxicity of herbal medicine oh the lab animal model(SD-Rat). There is no significant difference in body weight and kidney weight after herbal medication for 1 month. In all experimental groups, no abnormal findings were observed in histological study, and lab renal function index(BUN, creatinine, uric acid). These results say that four herbal multi-used-medicines, when medicated, is safe from the renal toxicity in lab animal model.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.263-266
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• 2017

Numerous maritime safety technologies and systems are being developed to support safe navigation at Sea. e-Navigation is a representative system for maritime safety. It is being developed to maximize the ships safety by applying most maritime safety technologies. The e-Navigation system is being developed by the International Maritime Organization (IMO) with the aim of introducing it by 2019. South Korea has already recognized the importance of maritime safety support technology and is actively introducing e-Navigation. Korean e-Navigation is being designed to provide diverse functions for maritime safety, such as providing an optimal safe route, risk analysis, and weather information. Service modules that provide e-Navigation's each function use different types of data that are difficult to configure as a single database. In this paper, we analyze the data needed for Korean e-Navigation, the data service system structure and types that can effectively support it.

• The KIPS Transactions:PartC
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• v.16C no.2
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• pp.257-266
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• 2009

Now a days, as increased the use of mobile units like a laptop computer and PDA, the demand for high speed internet service is increasing. On the other hand, PKMv2 which is provided from IEEE 802.16e cannot support fully on the security of high speed internet service. This paper proposes light-weight mutual authentication protocol which solved security problem of PKMv2 related to integrity of mobile node for transmission of safe high speed data of mobile node operating in mobile WiMAX environment. Proposed mutual authentication protocol increases the efficiency as the user in network can move in network safely without additional procedure of authentication between subscriber and base station after user's initial authentication. Also, the proposed mutual authentication protocol is safe from the security attack (the man-in-the-middle attack and reply attack) between subscriber and base station by generating a key adopt to PRF() function using random number and secret value in order to secure certification.