• Journal of IKEEE
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• v.5 no.2 s.9
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• pp.136-145
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• 2001

As with appearing new applications that requires QoS guarantee such as VoIP, VPN in Internet, problems of IP QoS has been one of most important issues in next-generation Internet. IETF has proposed integrated services model(Int-Serv) and differentiated service(Diff-Serv) to supply IP QoS in Internet. Int-Serv model uses the state information of each IP flow, so satisfies QoS according to traffic characteristics, but increases the amount of flow state information with increasing flow number. Diff-Serv model uses PHP(Per Hop Behavior), and there are well-defined classes to provide differentiated traffics with different services according to delay and loss sensitivity. Diff-Serv model can provide diverse services in Internet because of having no the state and signal information of each flow. As MPLS uses the packet forwarding technique based-on label, it implements the traffic engineering in the networks easily. The MPLS can set up the path with different traffic parameters, and assign each path to particular Class of Services. Therefore it is possible to support the Diff-Serv model with well-defined classes. In this paper we investigate the performance improvement of Diff-Serv function in the MPLS network to guarantee class of services in Internet.

• The Journal of the Acoustical Society of Korea
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• v.40 no.2
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• pp.139-147
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• 2021

This paper introduces and implements a Sound Event Detection (SED) system based on weakly-supervised learning where only part of the data is labeled, and analyzes the effect of parameters. The SED system estimates the classes and onset/offset times of events in the acoustic signal. In order to train the model, all information on the event class and onset/offset times must be provided. Unfortunately, the onset/offset times are hard to be labeled exactly. Therefore, in the weakly-supervised task, the SED model is trained by "strongly labeled data" including the event class and activations, "weakly labeled data" including the event class, and "unlabeled data" without any label. Recently, the SED systems using the mean-teacher model are widely used for the task with several parameters. These parameters should be chosen carefully because they may affect the performance. In this paper, performance analysis was performed on parameters, such as the feature, moving average parameter, weight of the consistency cost function, ramp-up length, and maximum learning rate, using the data of DCASE 2020 Task 4. Effects and the optimal values of the parameters were discussed.

• Journal of Korean Medical Science
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• v.33 no.52
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• pp.346.1-346.11
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• 2018

Background: To evaluate the therapeutic benefits of the treat-to-target (T2T) strategy for Asian patients with early rheumatoid arthritis (RA) in Korea. Methods: In a 1-year, multicenter, open-label strategy trial, 346 patients with early RA were recruited from 20 institutions across Korea and stratified into 2 groups, depending on whether they were recruited by rheumatologists who have adopted the T2T strategy (T2T group) or by rheumatologists who provided usual care (non-T2T group). Data regarding demographics, rheumatoid factor titer, anti-cyclic citrullinated peptide antibody titer, disease activity score of 28 joints (DAS28), and Korean Health Assessment Questionnaire (KHAQ) score were obtained at baseline and after 1 year of treatment. In the T2T group, the prescription for disease-modifying antirheumatic drugs was tailored to the predefined treatment target in each patient, namely remission (DAS28 < 2.6) or low disease activity (LDA) ($2.6{\leq}DAS28$ < 3.2). Results: Data were available for 163 T2T patients and 162 non-T2T patients. At the end of the study period, clinical outcomes were better in the T2T group than in the non-T2T group (LDA or remission, 59.5% vs. 35.8%; P < 0.001; remission, 43.6% vs. 19.8%; P < 0.001). Compared with non-T2T, T2T was also associated with higher rate of good European League Against Rheumatism response (63.0% vs. 39.8%; P < 0.001), improved KHAQ scores (-0.38 vs. -0.13; P = 0.008), and higher frequency of follow-up visits (5.0 vs. 2.0 visits/year; P < 0.001). Conclusion: In Asian patients with early RA, T2T improves disease activity and physical function. Setting a pre-defined treatment target in terms of DAS28 is recommended.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.11
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• pp.1427-1434
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• 2008

This study was aimed to compare nutrition knowledge, dietary attitude and habit of elementary school children with and without education. Eighty-four subjects with unbalanced eating behavior were selected and assigned to either control or education group. The subjects in education group participated in a nutrition education program once a week for 8 weeks. The contents of nutrition education were on food tower, balanced nutrition, nutrient function, food group, importance of breakfast, and nutrition label, etc and the program was performed by a school dietitian. The effects of education was assessed by self-administered questionnaire prior to and after nutritional education. Nutrition knowledge except on snack, dietary self-efficacy except on low fat/ low calorie, attitude except on functional food and favorite, and general dietary habits of children in education group were significantly improved while those in control group showed no changes. Also, factors for unbalanced eating was improved by nutrition education indicating the need for correction on unbalanced eating was diminished. However, children's adherence to snack, instant and fast food remained to be corrected. The dietary habit of balanced eating was improved by education reducing the percentage of unbalanced eating on grain and meat.fish.milk groups. The nutrition education appears to be effective to provide nutrition knowledge thereby to improve dietary attitude, dietary self-efficacy, and partly to reduce children's unbalanced eating factor.

• Korean Journal of Microbiology
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• v.38 no.2
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• pp.86-95
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• 2002

As a result of genome projects, the research to elucidate the function of a protein of interest has recently been well-recognized. In order to facilitate functional genomics, a useful mammalian gene expression vector is required. Using an infectious CDNA clone of BVDV pNADLclns-, we have developed a mammalian gene expression vector. In this study, a replication-competent full-length infectious CDNA clone containing puremycin acetyltransferase (pac) gene (pNADLclns-/pac) was successfully generated. The viral RNA replication and viral protein NS3 synthesis were examined by detecting metabollically $^{32}P$-labelled genomic viral RNA and immunoblotting with a mouse anti-NS3 antibody. To generate viral replicon as an expression vector, we examine if the viral structural genes (C, E0, El, E2) are required for viral replication by deletion analysis. As a result, all of the structural proteins are dispensable for viral replication per se, but essential for infectious viral particle formation. Based on our deletion analysis, we have generated a replication-competent BVDV viral replicon (pNADLclns-/pac/${\Delta}S$), whose structural genes are all deleted. In addition to NADLclns- /pac/${\Delta}S$, NADLclns-/ luc/${\Delta}S$ viral replicon containing luciferase gene as a reporter was constructed and fecund to be replication-compotent in HeLa and BHK cells as well as MDBK cells. Therefore, BVDV viral replicon developed in our study will be a useful tool to express a protein of interest in various mammalian cells.