• Title/Summary/Keyword: frequency-response

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Nitric oxide(NO)-mediated relaxation of bovine retractor penis muscle (소 음경후인근의 Nitric oxide(NO) 매개성 이완)

  • Yang, Il-suk;Chang, Hee-jung;Kang, Tong-mook;Lee, Jang-hern
    • Korean Journal of Veterinary Research
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    • v.36 no.3
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    • pp.599-605
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    • 1996
  • This study was designed to examine the mechanism of penile erection in adult bull by analyzing the responses of bovine proximal retractor penile muscle strips(BRP) to electtical field stimulation(EFS), exogenous nitric oxide(NO), NO synthesis precursor(L-arginine), NO synthase inhibitors(L-NAME, L-NMMA), guanylate cyclase inhibitor(methylene blue) and nonspecific potassium channel blocker(tetraethylammonium, TEA) treatments. Isometric tension of BRP was measured using physiograph. Results were summarized as follows: 1. EFS of nonadrenergic noncholinrgic(NANC) nerve in BRP produced frequency-dependent inhibitory responses to the contraction induced by co-treatment of epinephrine, guanethidine and atropine. The inhibitory responses to EFS were blocked by tetrodotoxin(TTX, $1{\mu}M$). 2. Treatment of L-NAME ($10,\;20{\mu}M$) inhibited the relaxation to EFS whereas L-NMMA ($100{\mu}M$) had no effect. 3. Treatment of NO($20,\;40{\mu}M$; as an acidified solution of $NaNO_2$) induced concentration-dependent relaxation whereas preincubation of TTX($1{\mu}M$) and L-NAME($20{\mu}M$) had no effect on the relaxation response. 4. L-arginine treatment(10mM) blocked the inhibitory effect of L-NAME($20{\mu}M$). 5. Pretreatment of methylene blue($40{\mu}M$) reduced the NANC-induced relaxation of BRP. 6. Tetraethylammonium(TEA, 80mM) reduced NANC relaxation. These results suggest that NO may act as a NANC neurotransmitter in BRP and the effects might be mediated by cGMP and potassium channel.

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Dynamic Property Identification of Structural Systems with Hinge Joint Using Equivalent Stiffness (등가강성모델을 활용한 힌지체결부 동특성 동정)

  • Won, Junho;Lim, Che Kyu;Lee, Doo-Ho;Choi, Joo-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.12
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    • pp.1635-1642
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    • 2012
  • The identification of the dynamic properties of structural joints is important for predicting the dynamic behavior of assembled systems. However, the identification of the properties using analytical or experimental approaches is extremely difficult or even impossible. Several studies have proposed hybrid or synthesis methods that simultaneously used analytical and experimental approaches to identify the dynamic properties of a joint. However, among the many types of joints, only the bolt joint was treated as a practical example in these studies. In this study, for a simple assembly system comprising two plates and one hinge joint, a simple methodology involving the use of the static-based subpart analysis method to identify the dynamic properties is proposed. Finally, the proposed method is applied to a glove box in a passenger vehicle that includes hinge joints.

Signal Processing for MoC Brake Rattle Noise of Moving Vehicles Using Prony Analysis (프로니 분석을 이용한 주행 환경에서의 브레이크 래틀 소음 발생 특성 분석)

  • Lee, Jaecheol;Kwak, Yunsang;Park, Junhong
    • Journal of the Korean Society for Nondestructive Testing
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    • v.35 no.4
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    • pp.245-250
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    • 2015
  • To verify the possibility of generating rattling noise from a motor on caliper brake system, a test was conducted using a caliper excited with vibrations similar to that in a vehicle running on actual roads; this test was conducted using a quiet shaker installed in an anechoic room. After several hours of external excitation, the test assembly was loosened, and the frequency of rattling noise generation increased. A microphone was used to record the generated noise. The measured signals were analyzed by conventional spectrum analysis. Since the noise is generated as an impact response, the advantages of employing Prony analysis was discussed, and the results were compared to those obtained using conventional fast Fourier transforms. The accuracy of Prony analysis was through endurance tests on different brake systems.

Rotordynamic Analysis of a Turbo-Chiller with Varying Gear Loadings Part II : A Driven High-Speed Compressor Pinion-Impeller Rotor-Bearing System (터보 냉동기의 변동 기어하중을 고려한 로터다이나믹 해석 Part II : 피동 고속 압축기 피니언-임펠러 로터-베어링 시스템)

  • 이안성;정진희
    • Journal of KSNVE
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    • v.9 no.5
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    • pp.1042-1049
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    • 1999
  • In the Part I has been reported a rotordynamic analysis of the driving motor-bull gear rotor-bearing system of a turbo-chiller. In this study, Part II, a rotordynamic analysis is performed with the turbo-chiller compressor pinion-impeller rotor system supported on two fluid film bearings. The pinion-impeller rotor system is driven to a rated speed of 14,600 rpm through a speed-increasing pinion-bull gear. It is modeled utilizing the finite element method for analysis. As loadings on the bearings due to the gear action are significant in the system considered, each resultant bearing load is calculated statically by considering the generalized forces of the gear action as well as the rotor itself. The two support bearings, the generalized forces of the gear action as well as the rotor itself. The two support bearings, partial and 3-axial groove bearings, are designed to take their varying loads along with their varying load angles, and they are also analyzed to give their rotordynamic coefficients. Then, a complex rotordynamic analysis of the compressor pinion-impeller rotor-bearing system is carried out to evaluate its stability, whirl natural frequencies and mode shapes, and unbalance responses under various loading conditions. Results show that the bearings and entire rotor system are well designed regardless of operating conditions, i.e., loads and operating speeds.

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The Influences of Immune Function and Respiratory System on Aerobic Exercise by Exposed Acute Hypobaric Hypoxic Environment. (급성 저압.저산소 노출에서의 유산소성 운동이 면역기능 및 호흡기계에 미치는 영향)

  • Lee, Dong-Jun
    • Journal of Life Science
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    • v.19 no.6
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    • pp.825-831
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    • 2009
  • The purpose of this study was to investigate the influences of immune function and respiratory system on aerobic exercise of 75 %HRmax intensity in an exposed acute hypobaric hypoxic environment. The subjects were 20 male college students, 10 of which were soccer players (19.6${\pm}$0.8 yr, BMI 22.3${\pm}$1.0, V02max 56.5${\pm}$4.8 mljkgjmin) and 10 general students (22.2${\pm}$2.3 yr, BMI 22.7${\pm}$2.1, $VO_{2max}$ 50.5${\pm}$6.6 ml/kg/min). Items of measurement after exercise on level and high altitude were $O_{2}$, $CO_{2}$, ventilation (VE), respiratory frequency, respiratory quotient, RBC, MCV, MCH, MCHC, Hb, Hct, reticulocyte, WBC, neutrophil, lymphocyte, monocyte, basophil, and immunoglobulin (IgA, IgD, IgG, IgM). As the result of the verifying hypothesis, these results may suggest three new findings: first, to produce hypoxic ventilatory depression not only at level land but also at 3,000 m high altitude during 30 minute aerobics exercise of 75 %HRmax intensity, second to be more excellent for soccer players in adaptation and sensibility on response of respiratory system at high altitude, and third, to change each other by regular exercise habits or altitude in the monocyte.

Differential Diagnosis of Hyperphenylalaninemias (고페닐알라닌혈증의 진단 및 평가)

  • Lee, Jeongho
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.15 no.3
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    • pp.110-117
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    • 2015
  • All infants should be screened for phenylketonuria (PKU) within the three days of life, in order to allow timely dietary intervention to protect children with PKU from neurologic damage in Korea. A commonly used cut-off level for diagnosis of PKU is $240{\mu}mol/L$ (4 mg/dL). Up to 2% of cases of hyperphenylalaninemias (HPA) detected by the screening test will account for a disorder of $BH_4$ metabolism. Therefore, analysis of blood or urinary pterins is essential, backed up with measurement of DHPR activity, as this allows differentiation of $BH_4$ disorders. A $BH_4$ loading test and measurement of neurotransmitters in CSF provide further important information to the severity of $BH_4$ deficiency and $BH_4$ loading test can detect patients with $BH_4$ deficiency and $BH_4$ responsive PKU. Several protocols for $BH_4$ loading test have been described, involving treatment with $BH_4$ for periods ranging from 1 day to 1 month, and using doses of $BH_4$ of 10-20 mg/kg. There is general agreement that a reduction on blood phenylalanine of at least 30% in response to $BH_4$ loading indicates a clinically significant effect, although in some tests a lower cut-off value may be defined for individual patients, or no specific cut-off value is proposed. The frequency of $BH_4$ responsiveness is highest in patients with mild HPA and mild to moderate PKU resulting from PAH mutations with residual activity.

Thermo-sensitive Clothing Development by Consumer Investigation and Wearing Test (소비자 조사와 착의 실험을 통한 온도감응형 기능성 의류개발을 위한 기초연구)

  • Sang, Jeong-Seon;Chung, Kyunghwa;Park, Juhyun;Oh, Kyung Wha
    • Fashion & Textile Research Journal
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    • v.19 no.1
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    • pp.90-100
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    • 2017
  • In this research, consumer awareness investigation and wearing test were carried out for obtaining useful data on the development of thermo-sensitive functional clothing material. A survey involved 216 people in Seoul and Kyeonggi-do, and 200 questionnaires data were analyzed by descriptive statistics and frequency using SPSS 17.0. Four healthy men in twenties were participated for wearing test. Subjects in normal loungewear were exposed to temperature change from the initial temperature $30^{\circ}C$ down to $5^{\circ}C$ for an hour in a climate chamber. The environmental temperature, surface temperature of garment and skin were measured. As a result, most of respondents have all season clothing products such as underwear, hosiery, and jogging suit for loungewear. Also, thermo regulator y functional clothes are frequently used as underwear and sweat shirt. The consumer awareness investigation on thermo regulatory functional clothing showed that the most important key buying factor is quick climate temperature response, easy maintenance, design and cost, in that order. Surface temperature of garment went down with the cooling down of environmental temperature. The lower environmental temperature, the greater temperature difference by body part showed. Skin temperature change by environmental temperature showed similar tendency of garment surface temperature. In comparison between garment surface and body skin, temperature difference became larger under the lower environmental temperature.

A Case of Deficiency of the Seventh Component of Complement with Recurrence of Meningococcal Meningitis and Septicemia (C7 결핍증과 연관된 재발성 수막구균 혈증 1례)

  • Lee, Jong-Seung;Yoo, Jung-Min;Yoo, Soo-Jung;Ko, Tae-Sung;Yoo, Han-Wook
    • Pediatric Infection and Vaccine
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    • v.11 no.2
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    • pp.212-215
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    • 2004
  • The complement system is important in the generation of the normal inflammatory response and in host defense against systemic infection. Therefore, inherited or acquired deficiency of complement is associated with an increased frequency of infection. As a major effector of the complement cascade, the membrane attack complex is responsible for direct complement dependent serum bactericidal activity. Especially late complement component deficiency has a markedly increased risk of meningococcal infection and is subject to recurrent infection. We experienced a patient who had recurrent meningococcal meningitis and septicemia. The patient was 13-years old boy and he had a recurrent episode after 20 months. At second admission, we examined complement level and C7 deficiency was confirmed. He was treated without complication. We report a case of deficiency of C7 with recurrent meningococcal meningitis and septicemia.

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Rotordynamic Model Development and Critical Speed Estimation Through Modal Testing for the Rotor-Bearing System of a MW Class Large-Capacity Induction Motor (MW급 대용량 유도전동기 축계의 모드실험 기반 회전체 동역학 해석모델 수립 및 위험속도 예측)

  • Park, Jisu;Choi, Jae-Hak;Kim, Dong-Jun;Sim, Kyuho
    • Tribology and Lubricants
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    • v.36 no.5
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    • pp.279-289
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    • 2020
  • In this paper, a method is proposed for establishing an approximate prediction model of rotor-dynamics through modal testing. In particular, the proposed method is applicable to systems that cannot be established according to conventional methods owing to the absence of information regarding the dimensions and material of the rotor-bearing system. The proposed method is demonstrated by employing a motor dynamometer driven by a 1 MW class induction motor without dimension and material information. The proposed method comprises a total of seven steps, wherein an initial model is established by incorporating approximate dimensions and material information, and the model is improved on the basis of the natural frequency characteristics of the system. During model improvement, the modification factor is introduced for adjusting the elastic modulus and shear modulus of the system. Analysis of critical speed and imbalance response indicates that the separation margin is 67% and the maximum vibration amplitude is less than the amplitude limit of 0.032 mm under the API 611 standard, which means that the motor dynamometer can stably operate at a rated speed of 1800 rpm. Hence, the obtained results validate the feasibility of the proposed method. Furthermore, for broad usage, it is necessary to accordingly apply and validate the proposed method for various rotor-bearing systems.

Ecological characteristics of cigarette beetle, Lasioderma serricorne F., on several leaf litters (몇가지 낙엽에서의 궐련벌레, Lasioderma serricorne F.(Coleoptera : Anobiidae), 생태적 특성에 관한 연구)

  • 오명희
    • Journal of the Korean Society of Tobacco Science
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    • v.22 no.1
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    • pp.51-57
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    • 2000
  • The feeding preference of cigarette beetles, Lasioderma serricorne F., was tested using various leaf litters. The number of the trapped L. serricome was 45.25$\pm$10.44 at flue-cured leaf tobacco, Nicotiana tabacum L., 23.50$\pm$6.0 at chinese juniper, Juniperus chinensis L., 1l.75$\pm$4.99 at oak, Qqercus acutissiuma C., and 1l.50$\pm$2.52 at rice-straw, (Oryza. sativa L.). The response of oviposition was 93.20$\pm$26.22 at flue-cured leaf tobacco, 53.60$\pm$11.82 at chinese juniper, 48.20$\pm$20.90 at oriental arborvitae, Thuja orientalis L., 31.80$\pm$18.10 at cherry-tree, Prunus serrulata var. spontanea M., and 29.40$\pm$13.7 at rice-straw. However, the oviposition was respectively low at gingko, Ginkgo biloba L.,(5.40$\pm$2.97), turf grass, Zoysia japonica S., (5.20$\pm$13.7), and oak (3.00$\pm$l.41). The augmentation was maximum at chinese juniper (27.33$\pm$19.44 of emerged adults) followed by Magnolia obovata (8.50$\pm$9.33). Fifty percent of the tested species leaf litters including cherry-tree did not show any augmentation. The adult activities after hibernation were primarily found in May and June at Kwangju and Suwon, and in April at Chungju. The field activity of L. serricome at Suwon was mostly lower than that at other places, except in August at Chungju. The first appearance of L. serricome was observed earlier at Chungju and Kwangju than at Suwon, and the frequency of insect appearance was high in July, August, and September. L. serricome could hibernate by feeding on many kinds of plant leaf litters and it's population could be maintained in the open field in Korea.

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