• 디지털융복합연구
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• 제16권1호
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• pp.35-45
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• 2018

본 연구는 유아들이 유치원이라는 공간을 실존적으로 경험함으로써 형성되는 장소성의 의미를 유아들의 놀이를 중심으로 탐구하고 있다. 이를 위해 유아들이 경험하게 되는 유치원의 모든 공간을 연구관찰 대상범위로 선택하였다. 연구를 수행하기 위해 유아 관찰과 비형식 면담 교사 심층면담을 통해 유아들의 자유선택활동 시간과 바깥놀이를 중심으로 동영상 촬영이 이루어 졌다. 연구결과 유아와 교사가 경험하는 실존적 공간으로서 유치원의 장소성은 경험과 관계속에서 형성되는 공간으로서의 장소성, 놀이의 공동생산 공간으로서의 장소성, 교육과 생활이 공존하는 공간으로서의 장소성, 유아들의 경험한 유치원에 의해 만들어진 특별한 공간, 소통에 의해 공유된 공간으로서의 장소성을 나타내는 것을 알 수 있었다. 유치원의 장소성은 유아들의 실존적인 경험과 관계를 맺고 있었으며 교사들은 공간에 대한 재해석이 필요함을 시사한다.

• 동아시아식생활학회지
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• 제19권1호
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• pp.96-104
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• 2009

Three kinds of grape yakju (Kyoho, Campbell and Moru) and grape-free control were fermented with rice using koji of Aspergillus kawachii as a fermenting agent, and their fermentation characteristics were investigated. For the three yakju, reducing sugar content decreased slowly over 2 days fermentation after an initial rapid decrease. In case of Brix, the reducing sugar content increased gradually after increasing rapidly during the first 2 days of fermentation. The Kyoho and Moru groups displayed a gradual increase in reducing sugar content after an initial 2-day decrease, and the sugar content of the Campbell group increased gradually during fermentation. Uniformly, pH increased gradually after an initial 2-day decrease, however total acid increased continuously throughout fermentation. Alcohol content of yakju showed almost no change after increasing until day 6 (Kyoho) of day 4 (others), with the control displaying the highest content. Control $\alpha$-amylase activity decreased gradually after an initial 2-day increase, while that of the three yakju decreased throughout fermentation. Activities of $\beta$-amylase activities paralleled the results of reducing sugar. Concerning total anthocyanin, the Moru and Campbell groups displayed a rapid increase until day 2, a decrease until day 12, and a gradual increase thereafter. While the Kyoho and control groups displayed virtually no change after an initial 2-day increase until day 12, after which a gradual increase also occurred. In concerning sensory evaluation, Moru yakju scored highest for violetness, flavor of grape, and sweet taste, and also displayed a low alcohol content. These attributed Moru yakju the preferred choice.

• 융합보안논문지
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• 제13권6호
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• pp.77-82
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• 2013

최근 네트워크 사용자의 가치 변화와 이용 패턴을 살펴보면, 단순 웹 정보, 단방향 정보습득의 일방적인 데이터 전달에서, 멀티미디어 활용의 증가, 보안 및 개인화의 요구 증대, 자유로운 이동성에 대한 욕구 증가 등의 변화가 생기고 있다. 이러한 욕구의 변화로 인해 개별적으로 제공되는 각각의 서비스는 점차 융합화된 형태의 통합 서비스로 발전하고, 네트워크 또한 각각의 서비스를 위한 개별 망에서 이용자의 다양한 통합 욕구를 실현시켜 주는 지능형 통합망의 형태로 발전할 것으로 전망되며, 관련한 기술의 핵심이 되는 통신망 제어기술 또한 급속히 발전하고 있다. 본 논문에서는 자원의 효율적 사용은 물론 다중 도메인 (multi-domain)환경에서 다계층 (multi-layer)간의 정보 전달을 최소화하고, 최적의 경로선택을 할 수 있는 방법을 제안하였다. 기존의 경로선택에서 각각의 계층에 대한 정보를 이용하여 경로를 선택한 것에 비하여 다계층 구조상에서 다 계층의 정보를 활용하여 경로선택에 대한 다각화를 통한 최적의 경로선택이 수행되도록 제안하였다.

• 한국전자통신학회논문지
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• 제6권5호
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• pp.739-748
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• 2011

2010년도 말 현재 국유지의 면적은 $24,086km^2$로 전체 국토면적인 $100,033km^2$의 24%를 차지하고 있다. 그동안 국유재산 관리정책은 국유재산법이 제정된 이래 다양하게 변화해 왔지만 여전히 문제점들이 나타나고 있다. 또한 최근인 2011년 4월 1일에 국유재산법이 전면 개정 시행되어 어느 정도 문제점이 해소되고 있지만 여전히 국유재산은 효율적, 경제적으로 관리 운용되지 못하고 있을 뿐만 아니라 국가의 공공목적과 국민의 복지향상을 위해서도 합리적으로 사용되지 못하고 있어 아직도 개선되어야 할 여지가 남아 있는 실정이다.

• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 1994년도 추계학술발표회 및 정기총회
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• pp.1-2
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• 1994

With the prevalence of computers in modern organizations, simulation is receiving more atention as an effectvie decision -making tool. Simualtion is a computer-based numerical technique which uses mathmatical and logical models to approximate the behaviror of a real-world system. However, iptimization of synamic stochastic systems often defy analytical and algorithmic soluions. Although a simulation approach is often free fo the liminting assumption s of mathematical modeling, cost and time consiceration s make simulation the henayst's last resort. Therefore, whenever possible, analytical and algorithmica solutions are favored over simulation. This paper discussed the issues and procedrues for using simulation as a tool for optimization of stochastic complex systems that are dmodeled by computer simulation . Its emphasis is mostly on issues that are speicific to simulation optimization instead of consentrating on the general optimizationand mathematical programming techniques . A simulation optimization problem is an optimization problem where the objective function. constraints, or both are response that can only be evauated by computer simulation. As such, these functions are only implicit functions of decision parameters of the system, and often stochastic in nature as well. Most of optimization techniqes can be classified as single or multiple-resoneses techniques . The optimization of single response functins has been researched extensively and consists of many techniques. In the single response category, these strategies are gradient based search techniques, stochastic approximate techniques, response surface techniques, and heuristic search techniques. In the multiple response categroy, there are basically five distinct strategies for treating the responses and finding the optimum solution. These strategies are graphica techniqes, direct search techniques, constrained optimization techniques, unconstrained optimization techniques, and goal programming techniques. The choice of theprocedreu to employ in simulation optimization depends on the analyst and the problem to be solved. For many practival and industrial optimization problems where some or all of the system components are stochastic, the objective functions cannot be represented analytically. Therefore, modeling by computersimulation is one of the most effective means of studying such complex systems. In this paper, after discussion of simulation optmization techniques, the applications of above techniques will be presented in the modeling process of many flexible manufacturing systems.

• Restorative Dentistry and Endodontics
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• 제45권2호
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• pp.21.1-21.12
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• 2020

The aim of this article was to review age-dependent clinical recommendations for appropriate root canal instrumentation techniques. A comprehensive narrative review of canal morphology, the structural characteristics of dentin, and endodontic outcomes at different ages was undertaken instead of a systematic review. An electronic literature search was carried out, including the Medline (Ovid), PubMed, and Web of Science databases. The searches used controlled vocabulary and free-text terms, as follows: 'age-related root canal treatment,' 'age-related instrumentation,' 'age-related chemo-mechanical preparation,' 'age-related endodontic clinical recommendations,' 'root canal instrumentation at different ages,' 'geriatric root canal treatment,' and 'pediatric root canal treatment.' Due to the lack of literature with practical age-based clinical recommendations for an appropriate root canal instrumentation technique, a narrative review was conducted to suggest a clinical algorithm for choosing the most appropriate instrumentation technique during root canal treatment. Based on the evidence found through the narrative review, an age-related clinical algorithm for choosing appropriate instrumentation during root canal treatment was proposed. Age affects the morphology of the root canal system and the structural characteristics of dentin. The clinician's awareness of root canal morphology and dentin characteristics can influence the choice of instruments for root canal treatment.

• 한국산학기술학회논문지
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• 제16권11호
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• pp.7838-7843
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• 2015

본 논문에서는 제 2형 당뇨병의 1차 선택약으로 사용되는 메트포르민 염산염이 통상적으로 1일 1000mg~2000mg의 고용량으로 투여되고 동시에 매우 높은 수성용해도를 가지므로 1일 1회 복용을 위한 약물방출제어시스템에 다량의 서방성 부형제를 필요로 하여 제형의 크기가 커져 복용이 어려운 문제점이 있다. 따라서 이를 개선하고자 상대적으로 수성용해도가 낮은 새로운 메트포르민 산부가염을 합성하여 서방성 정제에 적용하여 메트포르민의 방출을 확인하고자 하였다. 이를 위해 메트포르민 염산염을 원료로 하여 NaOH하에서 메트포르민 base를 만들고 여기에 산부가염을 반응시켜 6개의 새로운 메트포르민 산부가염들을 합성하였다. 또한 이들의 수성용해도를 측정하여 메트포르민 염산염에 비해 현저히 낮은 수성용해도를 가지는 메트포르민 스테아린산염을 확인하였고 메트포르민 서방성 제형에 적용하여 실제 약물의 방출제어에도 용출시험 결과, 12시간에서 약 2배의 약물방출제어 효과를 확인하였다. 결론적으로 새로운 메트포르민 산부가염을 통해 서방성 부형제의 양을 줄여 제형의 크기를 줄임으로써 보다 높은 환자의 복약순응도를 기대할 수 있을 것이다.

• Archives of Plastic Surgery
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• 제34권4호
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• pp.520-523
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• 2007

Purpose: Verrucous carcinoma is a rare, low-grade and well-differentiated squamous cell carcinoma, representing as a warty tumor. Estimation of the incidence for cutaneous lesions is not available because they are rare. We describe a case of verrucous carcinoma, a rare type, complication of a chronic pressure ulcer of duration more than 15 years. Methods: A 17-year-old boy presented with a large lesion involving the sacral area, which had been neglected for about 15 years. He had a history of surgical extirpation 2 years ago, but not cured. Examination revealed a cauliflower-like mass arising from an irregularly oval-shaped tumor which was $6.0{\times}4.5cm$ in size with signs of infection and ulcer. The lesion involved the sacrococcygeal area, spreading to both medial gluteal regions. The perianal skin did not appear to be directly affected. Results: A preoperative punch biopsy revealed a extremely well differentiated verrucous carcinoma. There were positive results in immunohistochemistry in the items of p53, p63, Ki-67. An 'en-bloc' excision of the tumor with the clinically normal surrounding tissue was carried out. Reconstruction was achieved by local regional flap. Histopathological findings of the excised area fully confirmed the preoperative biopsy report. It remained free of recurrence for a period of about 8 months. Conclusion: We believe that in patients with buttock involvement, regardless of the extent of such tumors, surgical therapy should be considered as the first-choice of treatment as reconstruction can be performed without excessive impairment for the patient.

• Journal of Trauma and Injury
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• 제21권1호
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• pp.8-14
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• 2008

Iatrogenic ureteral injury is a complication that can occur during a variety of pelvic or abdominal surgeries. The most frequent causes are gynecological ones, followed by colon and vascular surgeries. Management of ureteric injury depends on the time of diagnosis and the severity of organ damage. Injuries diagnosed intraoperatively should be treated immediately. Occasionally, intraoperative ureteral injury is overlooked, and symptoms of the late diagnosis of ureteral injury are usually nonspecific; therefore, the diagnosis is delayed for days or weeks postoperatively. Management of injuries diagnosed postoperatively is more complex. There are differing opinions on whether an initial conservative or immediate operative intervention is the best line of action. Delayed repair is suggested on the grounds that it will reduce inflammation and tissue edema. However, many authors are in favor of early repair, perhaps because tissue planes are easier to find before fibrosis becomes too dense. Ureteral injuries occurring at the level of the pelvic brim should be best managed with an end-to-end anastomosis, preferably around a ureteric stent. More distal injuries also should be ideally managed with an end-to-end anastomosis, after excision of the crushed or compromised segments. However, if the remaining distal segment is short, ureteral reimplantation is the procedure of choice. The Boari flap technique for ureteral reimplantation is invaluable in cases with a short proximal segment. Delayed recognition of iatrogenic ureteral injury may be associated with serious complications, so prompt recognition of ureteral injuries is important. Recognition of the injury before closure is the key to easy, successful, and complications-free repair. Increased awareness of the risk for ureteral damage during certain operative maneuvers is vital to prevent injury, and to decrease the incidence of iatrogenic injury. A sound knowledge of abdominal and pelvic anatomy is the best prevention.

• 한국가족복지학
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• 제57호
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• pp.183-215
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• 2017

본 논문은 돌봄민주주의 관점에서 중앙정부의 보육정책을 규범적 접근으로 분석했다. 저출산 고령화로 인한 돌봄공백이 신사회 위험으로 등장하면서 경제성장 중심에서 돌봄가치 중심으로의 패러다임 전환이 필요하다는 사회적 인식이 이루어졌다. 하지만 돌봄윤리가 개별 정책에 어떤 방식으로 반영되어야 하는가에 대한 구체적인 정책연구는 많이 이루어지지 못해왔다. 이에돌봄민주주의 관점의 '자유', '평등', '정의' 가치를 적용해서 보육정책을 분석하고 새로운 정책지향을 제시하고자 했다. 분석결과는 다음과 같다. 먼저, 자유 관점에서, 현재 보육정책은 자유선택의 제약으로 인해 공공성과 사회연대성이 담보되지 못하고 있다. 둘째, 평등관점에서 성별및 소득불평등으로 인한 계층화는 인종과 세대의 축이 더해지면서 더욱 복잡하고 다층적인 불평등을 초래했으며, 사적 돌봄의 악순환이 나타나고 있다. 셋째, 정의관점에서 과거로부터 축적되어 온 부정의는 조정을 통해 교정되지 못하면서 구조적 불평등이 오히려 심화되는 것으로 나타난다.