• Proceedings of the Ginseng society Conference
• /
• 1998.06a
• /
• pp.57-62
• /
• 1998

We hypothesized the primary effect of ginseng was to protect cell membrane fatty acids from decomposition caused by free radicals. To confirm the antioxidant effect of ginseng, we measured the inhibitory effect on the formation of thiobarbituric acid-reactive substances, an indicator of lipid peroxidation, and evaluated the free radical scavenging effect of ginseng by electron spin resonance spectrometer, and gas chromatography. The results showed that thiobarbituric acid-reactive substances formed and the loss of arachidonic acid during lipid peroxidation, and that hydroxyl (-like) radical peak formed by the iron complex (ferric nitrilotriacetate, an known free radical generator in vitro) were completely inhibited by ginseng extract. This antioxidant effect of ginseng may be responsible for its wide pharmacological actions in clinical practice. As the free radical reactions in general are rapid and non-specific, ginseng seems to act as a normalizer, rather than a general tonic, at the stages of acute or chronic active phase of the various diseases.

• The Korean Journal of Pharmacology
• /
• v.16 no.2 s.27
• /
• pp.1-7
• /
• 1980

As it has been reported that morphine induce antidiuresis, and antinatriuresis along with decrease in renal hemodynamics when given intracerebroventricularly[ivt], the renal action of nalorphine, a partial antagonist of morphine action, and its influence upon the morphine action were investigated in this study. $10{\mu}g/kg$ of nalorphine given into the lateral ventricle of the rabbit brain tended to decrease renal plasma flow and glomerular filtration rate and increase the reabsorption of free water in the tubules. $100{\mu}g/kg$ ivt significantly decreased urine flow rate and increased free water reabsorption, and tended to increase electrolyte excretion in spite of decrease in renal plasma flow and glomerular filtration, suggesting that ADH also involved in the antidiuresis. Morphine hydrochloride, $10{\mu}g/kg$, ivt, produced marked decrement in renal hemodynamics along with decreased excretions of sodium, potassium and water, and these morphine actions were alleviated by nalorphine given 20 min later. The natriuretic action of ivt nalorphine manifested itself uninfluenced by the morphine. These observations indicate that nalorphine ivt produces renal actions similar to those of morphine, though less potent, and that it can antagonize the latter action. It is suggested that morphine influences renal hemodynamics through nerve by stimulating the 'morphine receptor' in the brain, whereas nalorphine liberates ADH by the agonistic action on the 'nalorphine receptor'.

• Journal of Distribution Science
• /
• v.16 no.8
• /
• pp.39-50
• /
• 2018

Purpose - The ultimate purpose of this research is to analyze the influence of personal disposition on shopping value and behavioral intention by expanding the theory of planned behavior (TPB). Research design, data, and methodology - An attempt was made to examine the effects of personal disposition (reflecting duty-free shop characteristics) on three selective actions of consumers - compulsive buying, variety seeking, and price sensitivity. We conducted a questionnaire survey with the users of airport duty-free shops, downtown duty-free shops (offline), and online duty-free shops. In total, 410 copies of the questionnaire were analyzed using a structural equation model. Results - According to the results, compulsive buying, variety seeking, and price sensitivity significantly affected shopping value. Shopping value and subjective norms both had significant effects on attitude, the major variable in the TPB, and attitude had the greatest effect on behavioral intention, followed by subjective norms and perceived behavioral control in descending order. Conclusions - This study has academic implications in that it extends the existing theories of planned behavior and applies it to consumer characteristics and shopping value. It has practical implications as well in that it provides basic data that can be used to establish concrete marketing strategies for duty-free shop owners targeting segmented markets by closely examining customer desires.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.1
• /
• pp.37-43
• /
• 2021

The main objective of this study is to discuss the effect of free cash flow as a moderating variable on managers' decisions as regard earnings management. Companies with free cash flow are expected to refrain from taking opportunistic actions such as earnings management. The research used quantitative methods with sub-group moderating analysis. It is found that there is a significant relationship between past performance and earnings management, where the free cash flow is the moderating variable. The effect of past performance on earnings management is shown to slightly increase as free cash flow is considered. The findings of this study prove that earnings management is a practice that is often done by utilizing the flexibility of accounting recording and recognition mechanisms. Past performance becomes the main variable in encouraging managers to manage earnings by reducing revenue in the current period. This research can also be a reference in explaining managerial behavior and can be a reference to improving ethical human resource capabilities. This research focuses on companies in Indonesia that conduct earnings management by lowering profits as a result of declining past performance and examines aspects of free cash flow that reinforces the conduct of earnings management.

• IEIE Transactions on Smart Processing and Computing
• /
• v.3 no.5
• /
• pp.319-324
• /
• 2014

Web applications make life more convenient. Many web applications have several kinds of user input (e.g. personal information, a user's comment of commercial goods, etc.) for the activities. On the other hand, there are a range of vulnerabilities in the input functions of Web applications. Malicious actions can be attempted using the free accessibility of many web applications. Attacks by the exploitation of these input vulnerabilities can be achieved by injecting malicious web code; it enables one to perform a variety of illegal actions, such as SQL Injection Attacks (SQLIAs) and Cross Site Scripting (XSS). These actions come down to theft, replacing personal information, or phishing. The existing solutions use a parser for the code, are limited to fixed and very small patterns, and are difficult to adapt to variations. A machine learning method can give leverage to cover a far broader range of malicious web code and is easy to adapt to variations and changes. Therefore, this paper suggests the adaptable classification of malicious web code by machine learning approaches for detecting the exploitation user inputs. The approach usually identifies the "looks-like malicious" code for real malicious code. More detailed classification using sequence information is also introduced. The precision for the "looks-like malicious code" is 99% and for the precise classification with sequence is 90%.

• Korean Journal of Applied Biomechanics
• /
• v.13 no.3
• /
• pp.27-46
• /
• 2003

The purposes of this study were to determine the functions of actions of the limbs during each of the three support phases of the triple jump and their relationships with the performance of the triple jump. Four elite male triple jumpers were participated as subjects. The statistical analyses used were the Pearson product moment correlation coefficient for establishing relationships and simple regression analyses to determine and compare the relationships between the change of the horizontal velocity and the change of the vertical velocity during different support phases. A level of significance at p<.05 was set. The actions of the arms were responsible for about 25%, 25%, and 30% of the decrease in the horizontal velocity of the whole body center of gravity during the support phases of the hop, step, and jump, respectively. The change in the velocities of the whole body center of gravity due to the actions of the free limbs were significantly related with the whole body center of gravity during each support phase. The action of the support leg was associated with the decrease in the horizontal velocity and the increase in the vertical velocity of the whole body center of gravity during each support phase.

• Biomolecules & Therapeutics
• /
• v.1 no.2
• /
• pp.151-159
• /
• 1993

Effect of yohimbine, a specific antagonist for presynaptic adrenoceptor, on the renal action of clonidine, a specific presynaptic adrenoceptor agonist, was investigated in dog. Clonidine, when given intravenously, produced diuretic action accompanied with augmentation of osmolar and free water clearance (Cosm and 4C_{H_2O}$), and elicited the increase of amounts of sodium and potassium excreted in urine ($E_{Na}\; and\; E_k$). These actions of clonidine were inhibited by yohimbine either injected intravenously or infused into a renal artery. Clonidine, when infused into a renal artery, produced antidiuretic action accompanied with decreased of glomerular filtration rate (GFR) and renal plasma flow (RPF), and exhibited the reduced amounts of sodium and potassium in urine. These actions of clonidine injected into a renal artery were blocked by yohimbine administered either into vein or into a renal artery. Above results suggest that yohimbine block the renal action of clonidine only in central system, do not in kidney.

• IMMUNE NETWORK
• /
• v.9 no.1
• /
• pp.12-19
• /
• 2009

Heme oxygenase (HO)-1 is an inducible enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of free heme into ferrous iron, carbon monoxide (CO), and biliverdin (BV), the latter being subsequently converted into bilirubin (BR). HO-1, once expressed during inflammation, forms high concentrations of its enzymatic by-products that can influence various biological events, and this expression is proven to be associated with the resolution of inflammation. The degradation of heme by HO-1 itself, the signaling actions of CO, the antioxidant properties of BV/BR, and the sequestration of ferrous iron by ferritin all concertedly contribute to the anti-inflammatory effects of HO-1. This review focuses on the anti-inflammatory mechanisms of HO-1 actions and its roles in inflammatory diseases.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.10 no.9
• /
• pp.4487-4507
• /
• 2016

Recently tax authorities in the world have been adopting advanced information technology over the Internet into their processes. Websites that enable filing tax returns and paying tax electronically have been implemented in many countries. However, the tax authorities have difficulties in forcing the mandatory system because taxpayers do not feel comfortable with readily capturing their incomes by the system. This study aims to provide a guideline for successful implementation of the mandatory e-tax invoice system. First, the study foucsed on investigating whether the Korean e-tax invoice system was implemented successfully. Secondly, the study assessed actions that might contribute to its successful implementation. The analyses identify that establishing a free website for small-sized taxpayers and providing various issuing systems for diverse taxpayers are critical for its success. The results also enable the tax administrations aspiring to introduce a mandatory system to emphasize some specific actions, which have significant effects on its desired purposes. Finally, this study presents the various policy implications that previous studies have not provided.

• Journal of the Chungcheong Mathematical Society
• /
• v.31 no.4
• /
• pp.475-486
• /
• 2018

We study free actions of finite nonabelian groups on 3-dimensional nilmanifolds with the first homology ${\mathbb{Z}}^2{\bigoplus}{\mathbb{Z}}_2$ which yield an orbit manifold reversing fiber orientation, up to topological conjugacy. We show that those nonabelian groups are $D_4$(the dihedral group), $Q_8$(the quaternion group), and $C_8.C_4$(the $1^{st}$ non-split extension by $C_8$ of $C_4$ acting via $C_4/C_2=C_2$).