• 대한수학교육학회지:학교수학
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• 제11권3호
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• pp.463-477
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• 2009

수학적으로 그리고 역사적으로 중요한 의미를 갖는 소수는 초등학교부터 고등학교에 이르기까지 오랜 기간 동안 다루어지고 있다. 학생들이 소수 개념을 충실히 이해하도록 지도하기 위해서는 먼저 소수의 다양한 측면을 지도 과정에서 고려할 필요가 있다. 소수의 다양한 의미 지도를 간과할 경우, 이전에 배운 수 체계가 학생들의 소수 개념 이해를 제한하거나, 소수의 의미가 한 가지에 국한되어 소수의 계산이 힘들어 질뿐만 아니라 실수의 이해까지도 약화될 수 있다. 이에 따라 이 연구에서는 소수를 사용하는 다양한 상황에서의 소수의 역할과 기능에 주목하여 소수의 의미를 등분할 소수, 양 소수, 조작 소수, 비율 소수, 몫 소수, 배 소수로 구분하였고, 그것을 바탕으로 제7차 교육과정에 따른 초등학교 교과서에서 소수를 어떻게 도입하고 있는지 분석 비판하였다.

• 한국자동차공학회논문집
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• 제18권2호
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• pp.7-13
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• 2010

To satisfy the needs on fuel economy and engine performance, continuous variable valve lift systems are applying to engines. In the CVVL system, fuel economy can be improved by reducing pumping loss during the induction process, and engine performance can be also improved by controlling volumetric efficiency and the residual gas fraction. Because the residual gas fraction directly affects volumetric efficiency, engine performance, combustion efficiency and emissions in SI engines, controlling residual gas fraction is one of the important things in engine development process. This analysis investigates the residual gas fraction and volumetric efficiency with changes of intake valve lifts and intake valve timings. In this study, unsteady state solutions were solved during exhaust and induction processes. Results show variation of the residual gas fraction and volumetric efficiency by changing intake valve timing and lift. Decreasing intake valve lift leads to increase the residual gas fraction and to decrease volumetric efficiency.

• 소성∙가공
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• 제8권4호
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• pp.374-383
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• 1999

To determine the flow stress of semi-solid materials, a new combined method has been studied by experimental and analytic technique in the current approach. Using backward extrusion experiment and its numerical analysis, the characterization scheme of semi-solid materials according to the change of initial solid volume fraction has been proposed. Because that solid volume fraction is sensitive to temperature change, it is required to precisely control the temperature setting. Model materials can guarantee the establishment of material characterization technique from the noise due to temperature change. Thus, clay mixed with bonded abrasives was used for experiment and the change of initial solid fraction was copied out through the variation of mixing ratio. Upper bound method was adapted to increase in efficiency of the calculation in numerical analysis and new kinematically admissible velocity field was employed to improve the accuracy of numerical solution. It is thought that the material characterization scheme proposed in this study can be applied to not only semi-solid materials, but also other materials that is difficult to obtain the simple stress state.

• International Journal of Precision Engineering and Manufacturing
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• 제4권2호
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• pp.49-56
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• 2003

As semi-solid forging (SSF) is compared with conventional casting such as gravity die-casting and squeeze casting, the product without inner defects can be obtained from semi-solid forming and globular microstructure as well. Generally, SSF consists of reheating, forging, and ejecting processes. In the reheating process, the materials are heated up to the temperature between the solidus and liquidus line at which the materials exists in the form of liquid-solid mixture. The process variables such as reheating time, reheating temperature, reheating holding time, and induction heating power has large effect on the quality of the reheated billets. It is difficult to consider all the variables at the same time for predicting the quality. In this paper, Taguchi method, regression analysis and neural network were applied to analyze the relationship between processing conditions and solid fraction. A356 alloy was used for the present study, and the learning data were extracted from the reheating experiments. Results by neural network were in good agreement with those by experiment. Polynominal regression analysis was formulated using the test data from neural network. Optimum processing condition was calculated to minimize the grain size and solid fraction standard deviation or to maximize the specimen temperature average. Discussion is given about reheating process of row material and results are presented with regard to accurate process variables fur proper solid fraction, specimen temperature and grain size.

• KIEAE Journal
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• 제16권6호
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• pp.13-19
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• 2016

Purpose: In this study, we examined outdoor air fraction using historical data of actual Air Handling Unit (AHU) in the existing building during intermediate season and analyzed optimal outdoor air fraction by control types for economizer. Method: Control types for economizer which was used in analysis are No Economizer(NE), Differential Dry-bulb Temperature(DT), Diffrential Enthalpy(DE), Differential Dry-bulb Temperature+Differential Enthalpy(DTDE), and Differential Enthalpy+Differential Dry-bulb Temperature (DEDT). In addition, the system heating and cooling load were analyzed by calculating the outdoor air fraction through existing AHU operating method and control types for economizer. Result: Optimized outdoor air fraction through control types was the lowest in March and distribution over 50% was shown in May. In case of DE control type, outdoor air fraction was the highest of other control types and the value was average 63% in May. System heating load was shown the lowest value in NE, however, system cooling load was shown 1.7 times higher than DT control type and 5 times higher than DE control type. For system heating load, DT and DTDE is similar during intermediate season. However, system cooling load was shown 3 times higher than DE and DEDT. Accordingly, it was found as the method to save cooling energy most efficiently with DE control considering enthalpy of outdoor air and return air in intermediate season.

• IMMUNE NETWORK
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• 제12권6호
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• pp.291-295
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• 2012

We previously reported that Hydnocarpi Semen (HS) has a wound healing effect on diabetic foot ulcer lesion in mice. In this study, ethylacetate (EtOAc) fraction from HS extract were evaluated for their wound healing activity by using in vitro acute inflammation model. GC and GC/MS analysis shows that the main constituents in EtOAc fraction are chaulmoogric acid, hydnocarpic acid, and gorlic acid. EtOAc fraction activated macrophages to increase the production of TNF-${\alpha}$. The fraction also increased the production of TGF-${\beta}$ and VEGF, which induced fibroblast activation and angiogenesis. These results suggest that the mechanism that the fraction helps to enhance healing of skin wound is possibly associated with the production of TNF-${\alpha}$, as well as secretion of VEGF, TGF-${\beta}$ and HS may have a new bioactive material for the treatment of skin wound.

• 동의생리병리학회지
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• 제17권3호
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• pp.643-647
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• 2003

The Methylene Chloride(MC) fraction of Trichosanthis kirilowii Maxim has been investigated anti-tumor activities in vitro. The MC fraction of Trichosanthis kirilowii Maxim significantly inhibited the proliferation of human leukemic U937 cell with an IC50 of approximately 10μg/ml in a dose-dependent manner. We found that the MC fraction upregulated of caspase9 and caspase-3 activity and cleaved PARP expression but it didn't affect bax and bcl-2. which were demonstrated by western blot analysis. Taken together, these results exerted that the MC fraction suppessed human leukemic U937 cell proliferation by inducing apoptosis, suggesting the MC fraction of Trichosanthis kirilowii Maxim is possible to show anti-cancer activity in vivo.

• 한국태양에너지학회 논문집
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• 제39권6호
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• pp.41-54
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• 2019

The purpose of this study is to analyze the performance of solar thermal system according to regional weather conditions and feedwater temperature. The performance analysis of the system was carried out for the annual and winter periods in terms of solar fraction, collector efficiency and it's optimal degree. The system is simulated using TRNSYS program for 6 cities, Seoul, Incheon, Gangneung, Mokpo, Gwangju, and Ulsan. Simulation results prove that the solar fraction of the system varies greatly from region to region, depending on weather conditions and feedwater temperatures. Monthly average solar fraction for winter season from November to February, a time when heat energy is most required, indicated that the highest is 73.6% in Gangnueng and the lowest is 56.9% in Seoul. This is about 30% relative difference between the two cities. On the other hand, the collector efficiency of the system for all six cities was analyzed in the range between 40% and 42%, indicating small difference compare to the solar fraction. The annual average solar fraction is rated the highest at 40 collector degree, while monthly average solar fraction during winter season is rated at 60 degree.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권2호
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• pp.154-163
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• 2000

Growth factors and the receptors play an important role in the regulation of the growth and development of mammalian cells. In particular, epidermal growth factor is a polypeptide with potent mitogenic activity that stimulates proliferation of various normal and neoplastic cells through the interaction with its specific receptor(EGFR). EGFR has been described as a parameter of poor prognosis in many human neoplasms such as breast, bladder, and vulvar cancers. The objectives of this study are the evaluation of the expression of EGFR and cell cycle analysis in the head and neck squamous cell carcinomas(SCC), and the evaluation of the correlation between clinico-patholgic features and expression of EGFR and S-phase fraction. 37 head and neck squamous cell carcinoma specimens were evaluated for expression of EGFR by Western blot analysis and S-phase fraction by cell cycle analysis using the flow cytometry. The obtained results were as follows : 1. The expressions of EGFR were observed in 20 specimens(54%) among 37 head and neck SCC specimens. In case of oral SCC, 15 specimens(56%) out of 27 specimens were observed, and in case of nasopharyngeal SCC 5 specimens(50%) out of 10 specimens. 2. There was no correlation between clinical features(location, stage) of head and neck SCC and expression of EGFR (p>0.05). 3. There was a significant correlation between histo-pathological differentiation of head and neck SCC and expression of EGFR (p<0.02). 4. There was a significant correlation between expression of EGFR and S-phase fraction of cell cycle in the head and neck SCC (p<0.05). The above results suggest that expression of EGFR and S-phase fraction of cell cycle are adjunctive prognostic marker in the head and neck squamous cell carcinomas.

• 한국안전학회지
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• 제21권2호
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• pp.15-21
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• 2006

The railroad bogie's components experience repeated loading during service. Especially, oil damper bush has been fatigue fractured on the plane between rubber and steel stem during service, and which results in inferior of performance of the bogie. In this study, in order to offer a proper maintenance method of the bush, bubber bush used for the oil damper was fatigue tested and its damage fraction during service was estimated. Also, FEM analysis on the bush was conducted. When 1400, 1200, and 1000kgf of repeated loads were applied to the oil damper bush, final damage fraction exhibited 63.7%, 50% and 40%. From the results of FEM analysis, deformation energy density was found to be $0.5452kgf/mm^{2}$ at an applied load of 1400kgf and the location with maximum value coincided with the fractured location of the bush. Finally, it will be desirable to adopt the normalized damage fraction rather than absolute damage fraction in estimating remaining service lifetime of the bush.