• Bulletin of the Korean Chemical Society
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• v.25 no.6
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• pp.838-842
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• 2004

Amyloid peptide (A${\beta}$) is the major component of senile plaques found in the brain of patient of Alzheimer's disease. ${\beta}$-amyloid peptide (25-35) (A${\beta}$25-35) is biologically active fragment of A${\beta}$. The three-dimensional structure of A${\beta}$25-35 in aqueous solution with 50% (vol/vol) TFE determined by NMR spectroscopy previously adopts an ${\alpha}$-helical conformation from $Ala^{30}$ to $Met^{35}$. It has been proposed that A${\beta}$(25-35) exhibits pH- and concentration-dependent ${\alpha}-helix{\leftrightarrow}{\beta}$sheet transition. This conformational transition with concomitant peptide aggregation is a possible mechanism of plaque formation. Here, in order to gain more insight into the mechanism of ${\alpha}$-helix formation of A${\beta}$25-35 peptide by TFE, which particularly stabilizes ${\alpha}$-helical conformation, we studied the secondary-structural elements of A${\beta}$25-35 peptide by molecular dynamics simulations. Secondary structural elements determined from NMR spectroscopy in aqueous TFE solution are preserved during the MD simulation. TFE/water mixed solvent has reduced capacity for forming hydrogen bond to the peptide compared to pure water solvent. TFE allows A${\beta}$25-35 to form bifurcated hydrogen bonds to TFE as well as to residues in peptide itself. MD simulation in this study supports the notion that TFE can act as an ${\alpha}$-helical structure forming solvent.

• Economic and Environmental Geology
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• v.35 no.6
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• pp.533-544
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• 2002

In order to investigate the relative mobility (RM) of dissolved elements during processes controlling major and trace element content, the concentrations of major, minor and trace elements were reviewed from the previous data of $CO_2$-rich waters and granites from Kangwon Province. The relative mobility of elements dissolved in $CO_2$-rich waters is calculated from $CO_2$-rich water/granite ratio with normalizing by sodium. The results show that gaseous input of magmatic volatile metals into the aquifer is negligible in this study area, being limited by cooling of the rising fluids. Granite leaching by weakly acidic, $CO_2$-charged water is the overwhelming source of metals. Poorly mobile element (Al) is preferentially retained in the solid residue of weathering, while alkalis, alkaline earth and oxo-hydroxo anion forming elements (especially As and U) are mobile and released to the aqueous system. Transition metals display an intermediate behavior and are strongly dependent on either the redox conditions (Fe and Mn) or solid surface-related processes (adsorption or precipitation) (V, Zn and Cu).

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.265-271
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• 2020

This study aims to help the creative idea of nail art design and the expansion of artistic realm by presenting nail art applied with dot, line, and plane, which are the basic elements of the sculpture that make up the space for visual expression of nail art. The research method considered the concepts and characteristics of the molding elements through professional books, prior research, and Internet website. Along with various expression techniques, the characteristics of dot, line, and plane were applied to nail art and expressed as visual messages, and a total of six works were produced according to each characteristic. This research aims to find a new perspective on nail art expression by reinterpreting the characteristics of dot, line, and plane, which are formative elements, in an artistic approach, and to contribute to enhancing the infinite possibilities of nail art design by utilizing them.

• Korean Institute of Interior Design Journal
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• v.24 no.5
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• pp.51-61
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• 2015

The purposes of this study were to examine the characteristics of elements composing the cultural identity of Chinese architectural and spatial design, and to analyze the expression characteristics and influencing factors of contemporary restaurant design. With these purposes, first, this study reviewed related literature in order to find the characteristics of tangible elements observed in intangible elements and space expression characteristics forming the cultural identity of China. Second, this study conducted a case study in order to understand the expression characteristics of the design of Chinese restaurants in Shanghai and to find factors influencing the design. In order to sample the subjects of the case study, the researcher selected 18 restaurants that were recommended repeatedly in books on Chinese restaurants and tourism and major Internet sites or highly evaluated by visitors, and then choose 15 of them that were found to be fit for the purpose of the survey. According to the result of the survey, the restaurants were largely grouped by type into 10 cases of fine dining, 3 of middle-class casual dining, 1 of fast food, and 1 of luxury tea house serving traditional tea and snacks. Of these restaurants, 46.7% (7 cases) were of CM-CM-CM type, namely, using contemporary simple elements in all of external spaces, indoor spaces, and decorations, 20% (3 cases) were of CM-CM-CT type, using contemporary and simple external and indoor spaces, and traditional furniture or articles, 20% (3 cases) were of CT-CM-CT type, using traditional external spaces such as traditional buildings, contemporary simple finishing of indoor spaces, and traditional articles such as palace lanterns and traditional doors and windows, and 13.3% (2 cases) were of CT-CT-CT type, using traditional elements in their original forms in general. Through this research and survey, cultural identity showing Chinese traditions observed in the expression characteristics of restaurant spatial designs was confirmed, and it was also found that the identity was underlain by ideologies, values, lifestyles, etc. that had long accumulated through the long history of the country and exerted a great influence.

• Journal of Korea Multimedia Society
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• v.24 no.10
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• pp.1449-1460
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• 2021

The visual design elements of packaging play an vital role in attracting consumers' attention, forming their sense of pleasure and sensory expectations, as well as having an important impact on the actual product experience. This study aims to explore whether the colors and textures in the packaging design elements of canned beer will affect consumers' senses, judgments and taste perception of canned beer. Participants in Survey I (N=193) evaluated their expectations for beer freshness, softness, bitterness and alcohol content by observing the packaging of canned beer, then recorded whether they could get the expected experience when tasting beer, and evaluated their preference and purchase intention. In the Survey II, 4 kind of colors and 2 types of texture shapes were applied, and all participants were provided with the same beer for multivariate cross contract analysis to evaluate the specific impact of color and texture of packaging design elements on consumers' taste and the interaction between sensory judgment and taste perception.The results showed that both colors and textures had a significant affect on the sensory expectation (pre-tasting score) of canned beer, but their effects on the sensory score after tasting (actual perception)were inobvious. The analysis of the influence of the interaction between color, texture and shape on taste perception shows that when the expected packaging appearance perception is similar to the actual drinking perception (i.e., straight line and B/G or arc line and Y/R), it is more likely to obtain consumers' favor and higher purchase intention evaluation than the inconsistent canned beer packaging (i.e., straight line and Y/R and arc line and B/G). This paper discusses the influence of these results on the packaging design of canned beer and the possibility of improving the brand efficiency by meeting the visual elements of packaging design expected by consumers.

• Transactions of the Korean hydrogen and new energy society
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• v.22 no.3
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• pp.340-348
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• 2011

Effects of various inorganic-metal oxide (Zr, Zn, Si, Al and Ca as promoters and stabilizers) additive on the reduction rate of iron oxide and the composition of forming hydrogen using the steam-iron cycle operation was investigated. The reduction rate of redox agent with additive was determined from weight change by TGA. The changes of weight loss and reduction rate according to redox agent with various additive affected the hydrogen purity and cycle stability of the process. The cyclic micro reactor showed that hydrogen purity exceeding 95% could be obtained by the water splitting with Si/Fe, Zn/Fe, Zr/Fe redox agents. The redox agents with these elements had an affect on redox cycle stability as a good stabilizer for forming hydrogen by the steam-iron process.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.185-185
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• 2009

Micropump is very useful component in micro/nano fluidics and bioMEMS applications. Using the flexural vibration mode of PZT bar, a piezopump is successfully made. The PZT bar is polarized with thickness direction. The proposed structure for the piezo-pump consists of an input and an output port, piezoelectric ceramic actuator, actuator support, diaphragm. The traveling flexural wave along the bar is obtained by dividing two standing waves which are temporally and spatially phase shifted by 90 degrees from each other. Fluid is drawn into a forming chamber, eventually the forming chamber closes trapping the fluid therein. The finite elements analysis on the proposed pump model is carried out to verify its operation principle and design by the commercial FEM software. Components of piezopump were made, assembled, and tested to validate the concepts of the proposed pump and confirm the simulation results. The performance of the proposed piezopump the highest pressure level of 83.4kHz.

• Proceedings of the KIEE Conference
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• 2001.07c
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• pp.1631-1633
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• 2001

In manufacturing processes, various and suitable pulse shapes are required for the purpose of material processing and the pulseshape is regarded as a dominant factor due to the specific property of processing materials. Therefore, in this study, a variable pulse width, high duty cycle Pulse Forming Network(PFN) is constructed by time sequently. The power supply for this experiment consists of three switching circuits. The PFN elements operate at low voltage and drive the primary of HV leakage transformer. The secondary of the transformer has a full-wave rectifier, which passes the pulse energy to the load in a continuous sequence of properly phased and nested increments. We investigated laser pulse width as various delay time among three switching circuit. As a result, we tan obtain various laser pulse width from about 4ms to 10ms. The maximum laser pulse width obtained at this experiment was about 10ms at delay time of 4ms among each switching circuit.

• The Korean Journal of Ceramics
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• v.6 no.1
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• pp.47-52
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• 2000

Lanthanides such as La, Gd and Ce have recognized as elements of high level radioactive wastes immobilized by forming solid solution with $CaTiO_3$. For easy forming solid solution between $CaTiO_3$and lanthanides, the combustion synthesis process was applied and the powder characteristics and sinterability were investigated. The proper selection of the type and the composition of fuels are important to get the crystalline solid solution of $CaTiO_3$and lanthanides. When glycine or the mixtures of urea and citric acid with stoichiometric composition was used as a fuel, the solid solution of $CaTiO_3$with $La_2O_3$or $Gd_2O_3$or $CeO_2$was produced very well by the combustion process. The combustion synthesized powder seemed to have a good sinterability with the linear shrinkage of more than 25% up to $1500^{\circ}C$, while that of the solid state reacted powder was less than 10% at the same condition.

• Journal of Ocean Engineering and Technology
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• v.12 no.2 s.28
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• pp.57-64
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• 1998

This study is concerned with criterion for membrane to shell conversion in two-dimensional elastic-plastic finite element analysis using membrane/shell mixed element. It is well known that in the sheet metal forming some parts of the sheet deform under almost pure stretching (membrane) conditions, whereas other parts in contact with sharp tooling surfaces can develop significant bending strains. The membrane analysis has a short computational time however, in the membrane analysis the bending effects can not be condidered at all. On the other hand, the shell analysis allows the consideration of bending effects, but involves too much computational time. So Onatel),2), Yang et al3),4) developed the membrane/shell mixed element. Onate introduced the energy ratio parameter and Yang et al introduced the ratio of thickness to radius of curvature as the criterion. In the present study we propose a new criterion by using the angle between both side elements in the nodal point.