• 제목/요약/키워드: form defect

검색결과 310건 처리시간 0.026초

성견에서 Acelluar dermal matrix가 1면 골내낭 결손부의 치주조직 재생에 미치는 영향 (The effects of Acellular dermal matrix on the healing of 1 wall intrabony defects in dogs)

  • 박주언;김병옥;박주철;장현선
    • Journal of Periodontal and Implant Science
    • /
    • 제36권1호
    • /
    • pp.27-37
    • /
    • 2006
  • Although the main purpose of periodontal treatment to regenerate is the complete regeneration of periodontal tissue due to periodontal disease, most of the treatment cannot meet such purpose because healing by long epithelial junction. Therefore, diverse materials of resorbable and non-resorbable have been used to regenerate the periodontal tissue. Due to high risk of exposure and necessity of secondary surgical procedure when using non-resorbable membrane, guided tissue regeneration using the resorbable membrane has gain popularity, recently. However, present resorbable membrane has the disadvantage of not having sufficient time to regenerate date to the difference of resorption rate according to surgical site. Meanwhile, other than the structure stability and facile manipulation, acellular dermal matrix has been reported to be a possible scaffold for cellular proliferation due to rapid revascularization and favorable physical properties for cellular attachment and proliferation. The purpose of this study is to estimate the influence of acellular dermal matrix on periodontal ligament, cementum and alveolar bone when acellular dermal matrix is implanted to 1-wall alveolar bone defect. 4 dogs of 12 to 16 month old irrelevant to sex , which below 15Kg of body weight, has been used in this study. ADM has been used for the material of guided tissue regeneration. The 3rd premolar of the lower jaw was extracted bilaterally and awaited for self-healing. subsequently buccal and lingual flap was elevated to form one wall intrabony defect with the depth and width of 4mm on the distal surface of 2nd premolar and the mesial surface of 4th premolar. After the removal of periodontal ligament by root planing. notch was formed on the basal position. Following the root surface treatment, while the control group had the flap sutured without any treatment on surgically induced intrabony defect. Following the root surface treatment, the flap of intrabony defect was sutured with the ADM inserted while the control group sutured without any insertion. The histologic specimen was observed after 4 and 8 weeks of treatment. The control group was partially regenerated by periodontal ligament, new cementum and new alveolar bone. the level of regeneration is not reached on the previous formed notch. but, experimental group was fully regenerated by functionally oriented periodontal ligament fiber. new cementum and new alveolar bone. In conclusion, we think that ADM seems to be used by scaffold for periodontal ligament cells and the matrix is expected to use on guided tissue regeneration.

흡수성 차폐막과 동종탈회동결건조골 이식에 의한 치조골 재생의 병용효과 (Alveolar Bone Formation in Dogs using Vicryl Absorbable Mesh(Polyglactin 910) and Decalcified Freeze-Dried Bone Grafting)

  • 오은정;정현주;김영준
    • Journal of Periodontal and Implant Science
    • /
    • 제29권3호
    • /
    • pp.469-484
    • /
    • 1999
  • The purpose of this study was to evaluate new bone formation following guided bone regeneration by resorbable and nonresorbable membrane. Six adult mongrel dogs were used. The first, second, third, fourth premolars in the mandible of each dog were extracted. Two months after tooth extraction, a buccal dehiscence defect was surgically created on each edentulous area. The experimental sites were divided into three groups according to the treatment modalities ; Group I-a: surgical treatment only ; Group I -b: allogenic decalcified freezed dried bone grafting ; Group II-a : e- PTFE membrane placement only ; Group II-b : allogenic decalcified freezed dried bone grafting and e-PTFE membrane placement ; Group III-a : Vicryl(R) mesh placement only ; Group III-b : allogenic decalcified freezed dried bone grafting and Vicryl(R) mesh placement . The animals were sacrificed at 8 weeks after operation and the specimens were prepared for histologic and histometric examination. The results were as follows : Clinically, all defect sites were healed without exposure of barrier membrane after the eight weeks. In Group I-a, dense connective tissues were impinged in the bony defect area. Well vascularized and fibrous bone marrow indicated that bone formation was still taking place was found. In Group I-b, in areas closer to the periphery, lamellation of the newly formed bone would found. In Group II-a, beneath the e-PTFE membrane a dense layer of connective tissue covering the most external portions of the regenerated tissue was seen. The new bone surfaces were lined with osteoid and osteoblast. In Group II-b, a dense layer of connective tissue covering the most external portions of the regenerated tissue was observed beneath the e-PTFE membrane. A notable amount of alveolar ridge regeneration was seen with new rigdes with well-contoured form. In Group III-a, the new bone surface were lined with osteoid and osteoblast, indicating active bone formation. A clear demarcation could not be noted between the host bone and new bone. In Group III-b, a notable amount of alveolar ridge regeneration was seen with new ridges assuming wellcontoured form. In areas closer to the periphery, lamellation of the newly formed bone would found. As histometric examination, the amount of bone formation was gained from $12.8mm^2$ to $26.3mm^2$. It was significantly greater in group II-b and group III-b compared to other groups(p<0.05) . These results suggest that Vicryl(R) mesh after DFDB grafting used in guided bone regeneration could create and sustain sufficient space for new bone formation.

  • PDF

소형항공기용(반디호) 몰드 제작 기술개발 (Development of Mold Manufacturing Technology for Small)

  • 정도희;신성관;성기정;송병흠
    • 한국항공운항학회지
    • /
    • 제13권1호
    • /
    • pp.43-49
    • /
    • 2005
  • There are several ways to mold the complex material, and it is divided to vacuum pack mold, compression mold, and hand lay up for a high molecular substance as a basic material. Moreover, it can be divided to general manufacturing (Single form) and mold manufacturing(Mold form) under normal temperature for Firefly. Firefly was manufactured with hand lay up and general manufacturing that using the foam core, glass fabric, and template without mold. However, mold manufacturing that is producing the surface by semi-sandwich using thin foam core and glass fabric then reinforce the inside with spar and rib is on developing. Mold manufacturing can make easy to production, standardize the quality, and possible to mass producing. In this paper, we present the mold producing process for canard aircraft "Firefly", and the problems and solutions during producing Firefly. Moreover, it complements the defect that the problems caused by master manufacturing error when produce several masters of a large part, and make the manufacturing process to be shortened by the replacement from the supplementary plate to the foam that is installed when producing lay up mold.

  • PDF

펄스 레이저 증착법에 의한 ZnO:Li 박막 성장과 열처리 효과 (Effect of Thermal Annealing and Growth of ZnO:Li Thin Film by Pulesd Laser Deposition)

  • 홍광준
    • 한국재료학회지
    • /
    • 제15권5호
    • /
    • pp.293-300
    • /
    • 2005
  • ZnO:Li epilayers were synthesized on sapphire substrates by the pulesd laser deposition (PLD) after the surface of the ZnO:Li sintered pellet was irradiated by the ArF (193 nm) excimer laser. The growth temperature was fixed at $400^{\circ}C$. The crystalline structure of epilayers was investigated by the photoluminescence (PL) and double crystal X-ray diffraction (DCXD). The carrier density and mobility of epilayers measured by van der Pauw-Hall method are $2.69\times10cm^{-3}$ and $52.137cm^2/V{\cdot}s$ at 293 K, respectively. The temperature dependence of the energy band gap of epilayers obtained from the absorption spectra is well described by the Varshni's relation, $E_g(T)=3.5128eV{\cdot}(9.51\times10^{-4}eV/K)T^2/(T+280K)$. After the as-grown ZnO:Li epilayer was annealed in Zn atmospheres, oxygen and vaccum the origin of point defects of ZnO:Li has been investigated by PL at 10 K. The Peaks of native defects of $V_{zn},\;V_o,\;Zn_{int},\;and\;O_{int}$ showned on PL spectrum are classified as a donors or accepters type. We confirm that $ZnO:Li/Al_2O_3$ in vacuum do not form the native defects because ZnO:Li epilayers in vacuum existe in the form of stable bonds.

Curvilinear free-edge form effect on stability of perforated laminated composite plates

  • Zerin, Zihni;Basoglu, Muhammed Fatih;Turan, Ferruh
    • Structural Engineering and Mechanics
    • /
    • 제61권2호
    • /
    • pp.255-266
    • /
    • 2017
  • In this study, self-supporting roofing elements especially convenient for large-span structures such as stadium, airport terminal, mall, coliseum, etc. were examined with respect to critical buckling load. These elements were assumed as laminated composite plates and, variation of free-edge forms, cutout types and lamination configurations were used as design parameters. Based on the architectural feature and structural requirements, the effects of curvilinear free-edge form on critical buckling load were focused on in this research. Within this scope, 14 types of lamination configuration were specified according to various orientation angle, number and thickness of plies with a constant value of total plate thickness. Besides that, 6 different types of cutout and 3 different free-edge forms were determined. By combining all these parameters 294 different critical buckling load analyses were performed by using ANSYS Mechanical software based on finite element method. Effects of those parameters on critical buckling load were evaluated referring to the obtained results. According to the results presented here, it may be concluded that lamination conditions have more significant influence on the critical buckling load values than the other parameters. On the other hand, it is perceived that curvilinear free-edge forms explicitly undergo changings depending on lamination conditions. For future work, existence of delamination might be considered and progression of the defect could be investigated by using non-linear analysis.

Hot Wall Epitaxy(HWE) 법에 의해 성장된 $CuGaSe_2$ 에피레이어의 광발광 특성 (Photoluminescience propeerties for $CuGaSe_2$ epilayers grown by hot wall epitaxy)

  • 김혜정;홍광준
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
    • /
    • pp.100-101
    • /
    • 2008
  • To obtain the single crystal thin films, $CuGaSe_2$ mixed crystal was deposited on thoroughly etched semi-insulating GaAs(100) substrate by the hot wall epitaxy (HWE) system. The source and substrate temperatures were $610^{\circ}C$ and $450^{\circ}C$, respectively. After the as-grown $CuGaSe_2$ single crystal thin films was annealed in Cu-, Se-, and Ga-atmospheres, the origin of point defects of $CuGaSe_2$ single crystal thin films has been investigated by the photoluminescence(PL) at 10 K. The native defects of $V_{CU}$, $V_{Se}$, $Cu_{int}$, and $Se_{int}$ obtained by PL measurements were classified as a donors or acceptors type. And we concluded that the heat-treatment in the Cu-atmosphere converted $CuGaSe_2$ single crystal thin films to an optical n-type. Also, we confirmed that Ga in $CuGaSe_2$/GaAs did not form the native defects because Ga in $CuGaSe_2$ single crystal thin films existed in the form of stable bonds.

  • PDF

Nuclear Rac1 regulates the bFGF-induced neurite outgrowth in PC12 cells

  • Kim, Eung-Gook;Shin, Eun-Young
    • BMB Reports
    • /
    • 제46권12호
    • /
    • pp.617-622
    • /
    • 2013
  • Rac1 plays a key role in neurite outgrowth via reorganization of the actin cytoskeleton. The molecular mechanisms underlying Rac1-mediated actin dynamics in the cytosol and plasma membrane have been intensively studied, but the nuclear function of Rac1 in neurite outgrowth has not yet been addressed. Using subcellular fractionation and immunocytochemistry, we sought to explore the role of nuclear Rac1 in neurite outgrowth. bFGF, a strong agonist for neurite outgrowth in PC12 cells, stimulated the nuclear accumulation of an active form of Rac1. Rac1-PBR (Q) mutant, in which six basic residues in the polybasic region at the C-terminus were replaced by glutamine, didn't accumulate in the nucleus. In comparison with control cells, cells expressing this mutant form of Rac1 displayed a marked defect in extending neurites that was concomitant with reduced expression of MAP2 and MEK-1. These results suggest that Rac1 translocation to the nucleus functionally correlates with bFGF-induced neurite outgrowth.

Gamma분포형 함수 적합을 이용한 Clark 모형의 매개변수 간접추정 (An Indirect Approach Determining Parameters of Clark's Model Based on Model Fitting to the Gamma Distribution function)

  • 성기원
    • 한국수자원학회논문집
    • /
    • 제36권2호
    • /
    • pp.223-235
    • /
    • 2003
  • Clark 모형의 매개변수 추정방법을 개선하기 위하여, 순간단위도를 gamma 분포형 함수로 가정하여 매개변수를 추정한 후 이를 Clark 모형의 매개변수로 전환하는 간접 추정방법을 제안하였다. 이 방법은 전통적인 Clark 모형의 매개변수 추정방법의 개연적인 부정확성을 개선하는 특징과 더불어 Nash 모형과의 상관성을 파악할 수 있는 장점을 갖고 있다. 제안된 매개변수 추정방법을 위천 유역에 적용한 결과 만족할 수 있는 수준의 추정값을 얻을 수 있었으며 또한 유역의 도달시간-유하면적 관계를 나타내는 합성함수를 구축할 수 있었다. 또한 제안된 매개변수 추정방법은 미계측 유역에 대한 추정에 있어서도 높은 적용성을 보였다. 따라서 제안된 방법론은 기존의 매개변수 추정방법을 보조할 수 있는 충분한 대안으로 판단된다.

Hot Wall Epitaxy (HWE) 법에 의한 $CuInSe_2$ 단결정 박막 성장과 점결함 연구 (Study point defect and growth for $CuInSe_2$ single crystal thin film by hot wall epitaxy)

  • 유상하;홍광준
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
    • /
    • pp.152-153
    • /
    • 2007
  • $CuInSe_2$ single crystal thin film was deposited on thoroughly etched semi-insulating GaAs(100) substrate by the hot wall epitaxy (HWE) system. After the as-grown $CuInSe_2$ single crystal thin films was annealed in Cu-, Se-, and In-atmospheres, the origin of point defects of $CuInSe_2$ single crystal thin films has been investigated by the photoluminescence(PL) at 10 K. The native defects of $V_{Cu}$, $V_{Se}$, $Cu_{lnt}$, and $Se_{lnt}$ obtained by PL measurements were classified as a donors or acceptors type. And we concluded that the heat-treatment in the Cu-atmosphere converted $CuInSe_2$ single crystal thin films to an optical n-type. Also, we confirmed that In in $CuInSe_2$/GaAs did not form the native defects because In in $CuInSe_2$ single crystal thin films existed in the form of stable bonds.

  • PDF

Mg Delta-Doping Effect on a Deep Hole Center Related to Electrical Activation of a p-Type GaN Thin Film

  • Park, Hyo-Yeol;Jeon, Kyoung-Nam;Kim, Keun-Joo
    • Transactions on Electrical and Electronic Materials
    • /
    • 제11권1호
    • /
    • pp.37-41
    • /
    • 2010
  • The authors investigated the photoluminescence (PL) and the electron paramagnetic resonance (EPR) from an magnesium (Mg)-doped GaN thin film with a delta-doped layer. The regularly doped sample shows a PL peak at 2.776 eV for the as-grown sample, and the peak shifts to 2.904 eV and increases in intensity for the annealed sample. The delta-doped sample also shows the same PL peak as does the regularly doped sample. However, only the annealed delta-doped layer shows a sharp EPR with a small isotropic Lande g-factor, $g_{II}$, of 2.029. This resonance is attributed to the delta-doped layer, which forms a hole-bound Mg-N atomic structure instead of the $Mg_{Ga}-V_N$ defect complex, indicating that the delta-doped sample was not optically activated to form PL centers but was instead electrically activated to form a hole-bound state.