• Title/Summary/Keyword: foreign case study

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Expression Profiles and Pathway Analysis in HEK 293 T Cells Overexpressing HIV-1 Tat and Nucleocapsid Using cDNA Microarray

  • Park, Seong-Eun;Lee, Min-Joo;Yang, Moon-Hee;Ahn, Ka-Young;Jang, Soo-In;Suh, Young-Ju;Myung, Hee-Joon;You, Ji-Chang;Park, Jong-Hoon
    • Journal of Microbiology and Biotechnology
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    • v.17 no.1
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    • pp.154-161
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    • 2007
  • Human immunodeficiency virus type 1 (HIV-1) infections are responsible for a substantial number of deaths annually and represent a significant threat to public health. According to the latest study, the Tat (Transactivator of transcription) protein is essential in transcription and replication of viral genes, and is among the early expression genes involved in the life cycle of HIV. The virion NC (nucleocapsid) plays an important role in early mRNA expression and contributes to the rapid viral replication that occurs during HIV-1 infection. Therefore, we attempted to elucidate the relationship between the Tat protein and nucleocapsid protein. In a comparison of two independently prepared and hybridized samples, flag NC overexpressed HEK 293T cells and pTat overexpressed HEK 293T cells, and hybridization showed the differences in expression in each case. Among the microarray results confirmed with real-time reverse transcriptase assay, twelve genes were identified to be involved according to their gene expression profiles. Of approximately 8,208 human genes that were analyzed, we monitored candidate genes that might have been related to NC and Tat genes from gene expression profiles. Additionally, the pathways could be viewed and analyzed through the use of Pathway Studio software. The pathways from the gene list were built and paths were found among the molecules/cell objects/processes by the curation method.

대학도서관에 있어서 사서중심의 장서개발은 가능한가\ulcorner-부산대학교 도서관을 중심으로-

  • 김정근
    • Journal of Korean Library and Information Science Society
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    • v.20
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    • pp.61-105
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    • 1993
  • For decades, general services and accounting officers have been dominant forces in collection development activities in college and university libraries in Korea. The role of certified librarians has been rather peripheral. This has been allowed by the fact that library acquisitions departments had to be headed by non-librarian general administrative officers by the government regulation. The philosophy behind this regulation was that acquiring library materials was not any different from simple purchasing act of other useful goods in the marketplace. In affiliation with the element of general administrative officers, domestic book-sellers also had a great influence in collection building activities in college and university libraries in Korea. This has been made possible by the fact that no other people could su n.0, pply library materials, especially foreign library materials. It has been pointed out for years that the mechanism in which general administrative officers and domestic book-sellers had a greater say in library acquisitions activities was especially inefficient in acquiring wanted materials in wanted speed and in wanted price. In this mechanism, books and periodicals were mere goods. They were not perceived as intellectual property holding information and knowledge in them. Since the student movement to revolutionize the library system of the Pusan National University, September 1987 to December 1988, the creative and progressive elements in this university library have been making great efforts to change the acquisitions system in this library into a more efficient one by putting certified librarians at the center of the whole acquisitions process. These efforts have been successful to a certain degree. In this discursive study of the case of the Pusan National University Library, I have tried to achieve a social description of the library process in which progressively motivated librarians succeeded in alienating administrative officers and book-sellers and in grasping in their hands the hegemony in the collection building aspect of library activities. It has been discovered that this was possible only when the librarians were mature enough to have their kind of professionalism, i.e., professional ethics and craftsmanship.

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(An) Empirical Study on Relationship Between Technology Fator and Foreign Newly created Market Entry Timing : In the case of Born Global Firm (기술요인과 해외신규시장 진입시기관계에 대한 실증연구 : 본글로벌 중소기업을 대상으로)

  • Kim, En-Sun;Choi, Yun-Jeong;Park, Ji-Ho
    • Proceedings of the KAIS Fall Conference
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    • 2010.11b
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    • pp.870-873
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    • 2010
  • 본 연구는 국내 Born Global Firm의 기술요인들이 해외신규시장 진입시기에 미치는 영향에 관한 연구모형을 제시하고, 국내 Born Global Firm을 대상으로 이에 대한 인과관계를 실증 분석하였다. 기존의 해외시장 진입시기에 관한 선행연구를 토대로 기술경쟁력, R&D 네트워크, R&D 정보력을 독립변수로 설정하고, 이러한 요인이 Born Global Firm의 해외신규시장 진입시기에 영향을 미칠 것이라는 가설을 설정하였다. 기존 선행연구를 통하여 기술경쟁력의 대용변수로 지적재산권, R&D 투자비용, R&D 전담기구 기능을, R&D 네트워크는 부서간 협력, 국내외 공동연구, R&D 정보력은 R&D 관련 정보 수집능력(경쟁업체 R&D 동향정보, 관련 주요연구자 정보 등), R&D 관련 정보 분석능력(기술이슈 및 트렌드 분석, 기술수준 분석 등), R&D 정보 활용능력(R&D 기획, 응용 분야 확장 등) 등을 사용하고 기업 내부요인과 수출관련에 대한 가설을 설정하였다. 특히, 해외시장 진입형태 중 FDI, 계약에 의한 해외시장진입 보다는 국내에서 가장 많은 해외진입 형태인 수출에 초점을 맞추었다. 연구결과는 다음과 같다. 국내 107개의 Born Global Firm을 대상으로 다중회귀분석 한 결과, Born Global Firm의 직접수출에 가장 큰 영향을 주는 요인으로는 지적재산권과, 부서간 협력, R&D 정보 활용능력 등으로 나타났다. 특히 기술이슈 및 트렌드 분석 정보력은 해외시장 진입시기를 앞당기는 것으로 나타났다.

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Study on the Relationship between the Pay TV Subscriber's Genre Preference and VOD Purchase : Focusing on the Movie VOD of IPTV Service (<유료 방송 가입자의 장르 선호도와 VOD 구매의 관계에 관한 연구:IPTV 영화 VOD 이용을 중심으로>)

  • Jo, Sungkey;Lee, Yeong-Ju
    • The Journal of the Korea Contents Association
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    • v.16 no.11
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    • pp.91-102
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    • 2016
  • This paper investigates the relationship between the Pay TV subscriber's genre preference and VOD purchase by analyzing actual purchase data of movie VOD of IPTV subscribers for 8 months. The result shows as follows. First, in case of purchasing movie contents below 4000 won, user's genre preference was higher than that of using contents over 4,000 won. This means the subscribers tend to follow their genre preference when the mass-typed recommendation is limited. Second, those who purchase foreign contents show higher genre preference than those who purchase domestic movies. Third, subscribers who purchase more frequently and much more tend to use more diverse genres. Heavy users or those who have higher willingness to pay would consume more diverse contents. It implies that VOD use would increase by supplying the personal recommendation service based on the subscriber's genre preference.

A Study on the Principles of Good Faith under International Transaction -Focused on the CISG- (국제거래상 신의성실의 원칙에 관한 연구 - CISG를 중심으로 -)

  • Han, Nak-Hyun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.46
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    • pp.61-104
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    • 2010
  • The purpose of this work aims to analyse the principles of good faith under international transaction with CLOUT and UNILEX cases. Article 7(1) CISG sets the stage for the interpretation by promoting a uniform approach using good faith and the international charter of the convention. In other words, article 7(1) defines the purpose and the principle of interpretation and is applied to the Convention as a whole. As such, it also includes article 7(2), which goes beyond the big picture and settles the problems of gap filling. It is also important to understanding that the mandate of the CISG is to look for a solution, which is not only restricted to interpretation but extends to solving a problem. The problem in this work is to find out how gap filling is achieved and, because of the autonomous mandate of interpretation, to explain and understand its relationship with domestic law. The solution to the interpretation of article 7(2) must be found within the four corners of the CISG. To restate, article 7(2) describes two situations where gap filling is needed. First, if the matter is governed by the Convention but not expressly settled, then a gap must be filled in conformity with general principles on which it is based. Second, if the matter is not covered then the gap must be filled taking domestic law into consideration. There are two reasons why a matter may not be covered by the Convention. First and most obviously, it has been specifically exclude from the sphere of Application by the CISG itself, such as validity in article 4. Second, changes in business methods will lead to gaps. The United Nations has established a service known as CLOUT. This contains abstracts of hundreds of selected decisions of both courts and arbitration tribunals. And UNILEX is cosponsored by the Italian Centre for Comparative and Foreign Law Studies and UNIDROIT Contract Principles. The cases are in abstract format, but, when available, the full text of the case in the original language is also supplied.

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Developing the requirements of "National Important Facilities" according to the certification criteria of (ISO) (국제표준화기구(ISO)의 인증기준에 준하는 「국가중요시설」의 요구사항 개발)

  • Yim, Heon-Wook
    • Convergence Security Journal
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    • v.17 no.3
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    • pp.65-71
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    • 2017
  • "National important facilities" refers to facilities that have a great influence on national security and people's live s if enemy occupation, destruction, or functional paralysis is imposed by the Ministry of Defense Directive. In view of the case of nuclear plant hacking and the attack on the government building "National important facilities" could be the target of anti-social crimes. In the meantime, the "National important facilities" check is limited to the facilit y survey. so The purpose of this study is to develop generalized requirements. Therefore, comparing the requiremen ts of ISO 9001:2015 and ISO 27001:2013. There are only 8 differences(operating) out of 1-10. And the rest are used in common. In addition, we confirmed that the results of comparing the cases of domestic and foreign CPTED are within the "Six Principles". In Chapter 8, the principle of application of CPTED was inserted and the certification re quirements of the "National important facilities" management system were derived.

A Comparative Study of Outsourcing Culinary Part of Foodservice Industry Development. (외식사업발전을 위한 조리분야 아웃소싱 전략에 관한 연구 (평가측정치 개발절차를 중심으로))

  • 김기영
    • Culinary science and hospitality research
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    • v.7 no.3
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    • pp.13-34
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    • 2001
  • The case which it contracts with the dynamic result measurement system when actual outsourcing evaluation measurement is composed and then one result standard between the service supplier and the user is set, which owns jointly the expense which is reduced from that or the benefit which is created from that is increasing In the conclusion, for outsourcing management strategy of domestic foodservice industry in order to succeed, first it is accurate and examined that for what and how outsourcing should be introduced and as a result, what kind of result can be raised from that result\ulcorner Food service industry should be outsourced if you want to make more many investment in better humane resources, food & beverage-goods-security and education to provide eating-out service out of various business in food industry. When considering the actuality of the domestic foodservice industry that time it is appropriate, it sees. The foreign-brand goods which is introduced in the country are being executing in the 1ink of part management strategy. One of the most influential factor of domestic foodservice industry's management pressure is overspent management expenses, Does the namely expenses preparation effect reach which degree\ulcorner what kind of method can most decrease these expenses\ulcorner Doing grows the success and failure of the Korean foodservice industry controls result with the fact that it will operate with a big variable sees. The background which the domestic foodservice industry should introduce inevitably the outsiurcing system is to develop continuously nation foodservice industry in the way of cost curtailment of food-material, a labor cost curtailment with efficient application and synergic effect like specialty manpower utilization. The kindred competitive enterprises gradually concentrate management resource to the point ability from the present point of view which is increasing and a strategy position they secure, to prepare a competitive power, what sees it is important national industry must prepare a new paradigm. It is important to measure the result based on sales accomplishment in operation system dimension, and it is more important to appropriately apply regard of the evaluation measurement

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Developing Prevention System of Overseas Infectious Disease Based on MERS and Zika Virus Outbreak (중동호흡기증후군과 지카바이러스의 대응사례분석을 통한 해외유입 신종감염병 예방시스템 구축 방안)

  • Kim, Ja Young;Bang, Joon Seok
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.4
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    • pp.330-340
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    • 2016
  • Objective: The outbreak of Middle East Respiratory Syndrome (MERS) started in South Korea in May 2015 and the end of crisis was declared in December 2015 by Korea Centers of Disease Control and Prevention (KCDC). However, Zika virus emerged in less than 2 months following MERS and showed higher mortality than other countries. This study is to assess the current prevention system of overseas infectious diseases, based on MERS and Zika virus outbreak and to suggest effective response system for the future. Methods: We conducted two surveys on medical specialists working at tertiary general hospitals regarding the effectiveness of responding system by KCDC against MERS and Zika virus and education in individual medical institutions using 5-Likert points. Response system was examined in three different periods as initial period, spreading period, and post disease period. Results: Although medical specialists received the notifications in initial period, no practical prevention was proven to be placed in responding stage by medical facilities (averagely 3.5/5 points in total and sub-analyses). During spreading period, there were several academic seminars conducted, which were evaluated as helpful. In post disease period, all answered that there were changes on patient treatment in all medical facilities, with mainly report system and the treatment regulations in case of suspicious patients for infection. Only 49% respondents answered positive on the possibility of initial responses. For questionnaire items regarding Zika virus, all answered that there were notifications prior to the first outbreak of the infected patient. Eighty% of respondents were aware of 'the Guideline system for traveling to dangerous areas', and answered that the system was moderately effective (averagely 3.8/5 points in total). For the effectiveness of prevention measures for foreign novel disease by KCDC, the average point was 3.0 in both of total and sub-analyses. Conclusion: There is not enough response system to prevent infectious disease in medical institutional and governmental levels in Korea. It would warrant the modification of overall medical system to improve preventive measures for initial spread of such diseases.

An Experimental Study on Thermal Damage under Tunnel Fire Scenario to Concrete PC Pannel Lining (터널 화재시나리오에 따른 콘크리트 PC패널라이닝의 열적손상에 관한 실험적 연구)

  • Kim, Heung-Youl;Park, Kyung-Hun;Kim, Hyung-Jun
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.477-480
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    • 2008
  • In tunnel, though the frequency of fire occurrence is relatively lower than other structures, the characteristics of sealed space tends to cause the temperature to rapidly rise to more than $1000^{\circ}C$ within 5 minutes after fire, which might eventually lead to a large fire that usually results in a loss of lives and the damage to the properties, not to mention a huge cost necessary for repair and maintenance after fire. Referring to foreign tunnel fire scenarios, it clarified the heat transfer characteristics of concrete PC panel lining depending on fire intensity (ISO, MHC, RWS), and to identify the range of thermal damage, the evaluation was carried out using ITA standard. As a result, 39mm under ISO fire condition, 50mm under MHC and 100mm under RWS were measured. And when it comes to spalling, 30mm was measured under RWS. When PC panel was designed to serve the support, a fire resistance to the minimum depth of 100mm of the concrete that might be damaged under the fire shall be maintained, and in case of a non-support structure, PC lining shall have at least 100mm thickness.

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COVID-19 and Changes in Global Value Chains of Korea (코로나19와 한국의 글로벌가치사슬(GVC) 변화)

  • Koo, Yangmi
    • Journal of the Economic Geographical Society of Korea
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    • v.23 no.3
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    • pp.209-228
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    • 2020
  • The purpose of this study is to analyze the changes in trade and industry of Korea and suggest implications from the perspective of global value chains following the spread of COVID-19. To this end, products for prevention of epidemics which is directly related to COVID-19 and IT industries with high GVC participation were analyzed. Due to the spread of COVID-19, the variation in import and export of products for prevention of epidemics was large. In the case of masks, import and export of final goods changed drastically, but the change in intermediate goods was not significant relatively. Korea's IT industry has been differentiated according to major trading partners amid overall changes in GVCs which is summarized as higher forward participation and lower backward participation. While no particular change resulted from COVID-19 has yet been made directly, the need for diversification strategies should be taken into account at a time when the production links with China and Vietnam are close and the dependence on trade with these countries is high. The COVID-19 is still in progress, requiring corporate strategies and policy efforts to respond to changes in GVCs in the post-COVID-19 era.