Background: Post-tuberculosis (TB) sequelae is a commonly encountered clinical entity, especially in high TB burden countries. This may represent chronic anatomic sequelae of previously treated TB, with frequent symptomatic presentation. This pilot study was aimed to investigate the pulmonary functions and systemic inflammatory markers in patients with post-TB sequelae (PTBS) and to compare them with post-TB without sequelae (PTBWS) participants and healthy controls. Methods: A total of 30 participants were enrolled, PTBS (n=10), PTBWS (n=10), and healthy controls (n=10). Pulmonary function tests included spirometry and measurement of airway impedance by impulse oscillometry. Serum levels of matrix metalloproteinase (MMP)-1, transforming growth factor-β, and interferon-γ were estimated. Results: Slow vital capacity (SVC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, and peak expiratory flow were significantly lower in PTBS as compared to controls. SVC and FEV1 were significantly less in PTBS as compared to PTBWS. Total airway impedance (Z5), total airway resistance (R5), central airway resistance (R20), area of reactance (Ax), and resonant frequency (Fres) were significantly higher and respiratory reactance at 5 and 20 Hz (X5, X20) were significantly lower in PTBS as compared to PTBWS. Spirometry parameters correlated with impulse oscillometry parameters in PTBS. Serum MMP-1 level was significantly higher in PTBS as compared to other groups. Conclusion: Significant pulmonary function impairment was observed in PTBS, and raised serum MMP-1 levels compared with PTBWS and healthy controls. Follow-up pulmonary function testing is recommended after treatment of TB for early diagnosis and treatment of PTBS.
Journal of the Korea Academia-Industrial cooperation Society
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v.13
no.7
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pp.3030-3036
/
2012
The purpose of this study was to investigate the efficacy of mechanical in-exsufflator (MI-E) with on pulmonary rehabilitation in stroke patients with trachostomy tube. Methods: We studied ten stroke patients who had neither history nor radiologic finding of pulmonary disease. The pulmonary function was evaluated by measuring forced vital capacity (FVC), forced expiratory volume at one second (FEV1) and forced expiratory ratio (FEV1/FVC) The capacity of cough was evaluated by measuring manual assisted peak cough flow (MPCF). Data were analyzed statistically using repeated ANOVA test. Results:The results were as follows : 1) There are significant improvement of FVC and FEV1 according to training period (p<.05). 2) There are significant improvement of MPCF according to training period (p<.05). Conclusion:These results suggest that MI-E training can be used as an effective therapeutic modality for improvement of pulmonary function and capacity of cough in stroke patients with tracheostomy.
Purpose: This study examined the effects of gym ball stabilization exercises on the physical functions of elementary school baseball players. Methods: The elementary school baseball players were assigned to an experimental group (n=21). The group performed gym ball stabilization exercises and the changes in the physical functions were measured using the visual response speed test, functional movements, physical balance ability, and pulmonary function. Results: The results of the visual response speed test showed changes in the time response speed. There was a significant change in the number of touches in 15 seconds in the upper arms and left and right legs (p<0.05) after 10 weeks. Also, there was a significant change in the reaction times of the left and right legs after 10 weeks (p<0.05). Further, there were significant differences in functional movements involving rotational stability and the total functional scores after 10 weeks (p<0.05). The player's body balance ability showed a significant difference after 10 weeks in the posterior-lateral and posterior-medial composite scores of the left and right legs (p<0.05). There was a significant change in the forced lung capacity and forced expiratory volume in 1 second after 10 weeks (p<0.05). Conclusion: These results show that the gym ball stabilization exercises effectively improved the visual response speed and functional movements, balance, and vital capacity of elementary school baseball players.
Journal of Korean Academy of Fundamentals of Nursing
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v.16
no.2
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pp.214-222
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2009
Purpose: The purpose of this study was to evaluate the effects of a walking-support program on the pulmonary ventilatory functions of elderly people who had undergone upper-abdominal surgery. Method: The study was a quasi-experimental research design. There were 26 partcipants who were admitted for upper-abdominal surgery to P University Hospital in B city. Walking exercise education was provided individually to the experimental group the day before their operation and 20 minutes a day for five days after the surgery using the 'Walking Exercise Guide Document'. Pulmonary ventilatory function was with FVC (Forced Vital Capacity), PEF (Peak Expiratory Flow), FEVI (Forced Expiratory Volume in 1 Second), FER (Forced Expiratory Ratio), Oxygen Saturation, and VAS (Visual Analog Scale). Results: The objective indexes of pulmonary ventilatory function were not significantly different between the two groups, but the subjective index was significantly different. Conclusion: With the above results, the walking support program could be an effective nursing intervention for improving pulmonary ventilatory function of surgical patients.
Journal of Korean Academy of Fundamentals of Nursing
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v.5
no.1
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pp.107-124
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1998
Based on King's goal attainment theory, this research deals with applying nursing intervention of mutual goal settings to gastrectomy patients. It tests the effects of nursing intervention, according to the patients' health locus of control, suggested as external boundary criteria for the theory by employing a quasi-experimental design which consists of a pretest-posttest non-equivalent control and experimental groups. The subjects of this research were 62 gastrectomy patients hospitalized at Y medical center and the experimental and control groups consisted of 31 subjects. The experimental group received nursing intervention at the mutual goal setting of 5 times from the day before the surgery to the 5th day after the surgery, while the control group received only routine nursing care. Recovery indicators of both groups were measured and compared. Measurement variables included patients' characteristics, health locus of control, forced vital capacity, forced expiratory volume in one second, peak expiratory flow, bowel movement recovery, mobility recovery, level of pain, patients' stress and patients' satisfaction. Data were analyzed using SPSS statistical package and the hypotheses were tested by ANOVA and ANCOVA. Results of the analyses are summarized as follows : 1) Internal health locus of control had higher effects of the nursing intervention of mutual goal setting than external health locus of control on pulmonary ventilatory functions of forced vital capacity, forced expiratory volume in one second, and peak expiratory flow. 2) There was no statistically significant difference in the effects of nursing intervention of mutual goal setting on the bowel movement recovery between the internal and external health locus of control. 3) There was no statistically significant difference in the effects of nursing intervention of mutual goal setting on the mobility recovery between the internal and external health locus of control. 4) There was no statistically significant difference in the effects of nursing intervention of mutual goal setting on the level of pain between the internal and external health locus of control. 5) There was no statistically significant difference in the effects of nursing intervention of mutual goal setting on the level of stress between the internal and external health locus of control. 6) There was a statistically significant difference in the effects of nursing intervention of mutual goal setting on the level of satisfaction with provision of nursing information between the internal and external health locus of control, and there was no statistically significant difference in the effects of nursing intervention of mutual goal setting on the level of satisfaction with outcome of nursing between the internal and external locus of control. On the basis of the research results, the following are recommended : 1) Repeated research on responses to health locus of control is necessary. 2) Not only the effectiveness of nursing intervention in acute recovery periods, but also the long term effects are to be investigated. 3) The development of instruments is needed to accurately measure mutual goal setting regarding postoperative deep breath, coughing, early ambulation, etc. so that the relationship among the postoperative recovery indicators may be explored. 4) It is required that an instrument be developed to measure perception which facilitates goal attainment in the interactive setting between patients and nurses.
This study was attempted to identify the health-related quality of life of Chronic Obstructive Pulmonary Disease (COPD) patients and factors influencing the quality of life, focusing on Health-related quality of life with 8 items (HINT-8). The subjects of this study were 451 adults aged 40 years or older who performed lung function tests and whose ratio is less than 0.7 by measuring forced respiratory volume in 1 second [FEV1] to forced vital capacity in the 2019 National Health and Nutrition Examination Survey, It was analyzed using SAS program. As a result, both the HINT-8 index and EuroQol five-dimensions 3-level version (EQ-5D-3L) index were appropriate as tools to measure the health-related quality of life in COPD patients, and the factors affecting the health-related quality of life were age, gender, income, and smoking status, comorbidities, stress, and subjective health status. Therefore, in order to improve the health-related quality of life of COPD patients, an individualized management program suitable for the characteristics of subjects such as the low-income class and the elderly, including smoking cessation education and stress management, should be developed and applied.
Journal of The Korean Society of Integrative Medicine
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v.12
no.2
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pp.133-140
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2024
Purpose : People who have suffered from COVID-19 suffer from decreased pulmonary function and various side effects. This study aims to present three respiratory exercise intervention methods to improve pulmonary function in COVID-19 survivors. Therefore, the purpose of this study will investigate the effects of breathing exercise interventions (aerobic exercise, diaphragm breathe exercise, and inspiratory muscle training on resistance) on pulmonary function in COVID-19 survivors. Methods : The subjects who participated in this study were 35 male and female college students confirmed with COVID-19. All subjects were randomly assigned to A, D, and I groups according to breathing exercise intervention method. Groups A, D, and I each performed aerobic exercise, diaphragm breathing exercise, and inspiratory muscle training on resistance, 3 times a week for 6 weeks. Pulmonary function was measured using a spirometer, and FVC (forced vital capacity), FEV1 (forced expiratory volume in one second), FEV1/FVC % (forced expiratory volume in one second / forced vital capacity ratio), and PEF (peak expiratory flow) were measured at 0, 3, and 6 weeks. Data analysis was compared by repeated measures analysis of variance, and post hoc tests for time were compared and analyzed using paired t-tests. Results : In the results of this study, FVC values showed statistically significant improvement in all groups. FEV1 values also showed statistically significant improvement in all groups. And the FEV1/FVC % value also showed statistically significant improvement in all groups. And the PEF values also showed statistically significant improvement in all groups. Conclusion : The results of this study reported that aerobic exercise, diaphragm breathing exercise, and resistance inspiratory muscle training were all effective in improving pulmonary function in COVID-19 survivors. Therefore, application of the three breathing exercise intervention methods presented in this study will help improve pulmonary function in COVID-19 survivors.
The Journal of the Convergence on Culture Technology
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v.7
no.4
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pp.203-210
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2021
This study examined the effect of the respiratory training centered at forced breathing exercise of blowing out a candle on the improvement of adults' respiratory ability, which means the increased muscle strength of body trunk. After the four-week candle-blowing breathing training, the forced vital capacity (FVC) increased statistically significantly (p<.05). The forced expiratory volume in one second (FEV1) did not show a statistically significant difference before and after the four-week intervention(p>.05). The peak expiratory flow rate (PEF) statistically significantly increased after the four-week blowing-out-the-candle training (p<.05). This study examined the relationship between forced breathing training and pulmonary function of healthy adults including FVC, FEV1, and PEF, which means the increased muscle strength of body trunk, by implementing blowing-out-the-candle breathing exercise centered at forced respiratory exercise and obtained significant results. Further studies that use a sample of patients with advanced respiratory system disease for whom physical therapy is absolutely necessary will be required in the future.
Hye Jeon Hwang;Joon Beom Seo;Sang Min Lee;Namkug Kim;Jaeyoun Yi;Jae Seung Lee;Sei Won Lee;Yeon-Mok Oh;Sang-Do Lee
Korean Journal of Radiology
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v.22
no.10
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pp.1719-1729
/
2021
Objective: Emphysema and small-airway disease are the two major components of chronic obstructive pulmonary disease (COPD). We propose a novel method of quantitative computed tomography (CT) emphysema air-trapping composite (EAtC) mapping to assess each COPD component. We analyzed the potential use of this method for assessing lung function in patients with COPD. Materials and Methods: A total of 584 patients with COPD underwent inspiration and expiration CTs. Using pairwise analysis of inspiration and expiration CTs with non-rigid registration, EAtC mapping classified lung parenchyma into three areas: Normal, functional air trapping (fAT), and emphysema (Emph). We defined fAT as the area with a density change of less than 60 Hounsfield units (HU) between inspiration and expiration CTs among areas with a density less than -856 HU on inspiration CT. The volume fraction of each area was compared with clinical parameters and pulmonary function tests (PFTs). The results were compared with those of parametric response mapping (PRM) analysis. Results: The relative volumes of the EAtC classes differed according to the Global Initiative for Chronic Obstructive Lung Disease stages (p < 0.001). Each class showed moderate correlations with forced expiratory volume in 1 second (FEV1) and FEV1/forced vital capacity (FVC) (r = -0.659-0.674, p < 0.001). Both fAT and Emph were significant predictors of FEV1 and FEV1/FVC (R2 = 0.352 and 0.488, respectively; p < 0.001). fAT was a significant predictor of mean forced expiratory flow between 25% and 75% and residual volume/total vital capacity (R2 = 0.264 and 0.233, respectively; p < 0.001), while Emph and age were significant predictors of carbon monoxide diffusing capacity (R2 = 0.303; p < 0.001). fAT showed better correlations with PFTs than with small-airway disease on PRM. Conclusion: The proposed quantitative CT EAtC mapping provides comprehensive lung functional information on each disease component of COPD, which may serve as an imaging biomarker of lung function.
Journal of The Korean Society of Integrative Medicine
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v.8
no.4
/
pp.155-161
/
2020
Purpose : This study was conducted to investigate the effect of positive active pressure technique and active breathing technique on lung function in healthy adults. Methods : In this study, the passive lung expansion technique and active respiration enhancement technique using an air mask bag unit were conducted in 30 normal adults to observe changes in pulmonary function with forced vital capacity (FVC), Forced expiratory volume at one second (FEV1). In order to observe the change in the level of respiratory function, we would like to investigate the peak expiratory flow (PEF) and the forced expiratory flow (FEF 25-75 %). Results : As a result of this study, there was no significant difference in comparison between the passive lung expansion technique and the active breathing enhancement technique (p>.05). The passive lung expansion technique effectively increased the effortful expiratory volume and the median expiratory flow rate of 1 second (p<.05). And the passive lung expansion technique effectively increased the effortless lung capacity and the maximum expiration flow rate (p<.05). Conclusion : The passive lung expansion technique effectively increases the range of motion of the lungs and chest cages, intrathoracic pressure, and elasticity of the lungs, and the active breathing technique increases the muscle functions such as the diaphragm and the biceps muscles. It is expected that it will be able to selectively improve the respiratory function of patients with respiratory diseases or functional limitations as it is found to be effective.
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