• Title/Summary/Keyword: food and drug

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INHIBITION OF NEURITE OUTGROWTH AND TRANSCRIPTION FACTOR ACTIVATION BY OCHRATOXIN A IN CULTURED PC-12 CELLS

  • Hong, Jin-Tae;Oh, Jae-Ho;Jung, Kyoung-Mi;Lee, Eun-Hee;Park, Ki-Sook;Song, Chi-Won;Jung, Hai-Kwan;Lee, Myung-Koo;Yang, Ki-Hwa;Chung, Soo-Youn
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.168-168
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    • 2001
  • The mycotoxin, ochratoxin A (OTA) has been known to induce microcephaly in animals and in vitro whole embryo. Cytotoxic effect and inhibition of cell differentiation were proposed as underlying mechanisms responsible for OTA-induced microcephaly.(omitted)

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Classification based on Near-IR spectra with application to Cnidium Rhizome

  • Cho, Chang-H.;Ze, Keum-R.;Sung, Rak-S.;Lee, Jog-P.;Park, Ju-Y.;Park, Sang-Y.;Jung, Young-J.;Cho, So-Y.;Jin, Zhexiong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.405.2-405.2
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    • 2002
  • A near infrared (NIR) method was developed to analyze specious diversity for morphologically similar umbelliferous herbal medicine. Cnidium officinale Makino. This herbal medicine has been widely used as 'chungung' without any discrimination of its quality and original plants. though it has the ambiguous origins of plants between various countries especially Korea. China and Japan. It is named by Cnidium officinale Makino in Korea and Japan. in comparison with Ligusticum chuanxiong Hort. in China. (omitted)

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Total Diet Studies as a Tool for Ensuring Food Safety

  • Lee, Joon-Goo;Kim, Sheen-Hee;Kim, Hae-Jung;Yoon, Hae-Jung
    • Toxicological Research
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    • v.31 no.3
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    • pp.221-226
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    • 2015
  • With the diversification and internationalization of the food industry and the increased focus on health from a majority of consumers, food safety policies are being implemented based on scientific evidence. Risk analysis represents the most useful scientific approach for making food safety decisions. Total diet study (TDS) is often used as a risk assessment tool to evaluate exposure to hazardous elements. Many countries perform TDSs to screen for chemicals in foods and analyze exposure trends to hazardous elements. TDSs differ from traditional food monitoring in two major aspects: chemicals are analyzed in food in the form in which it will be consumed and it is cost-effective in analyzing composite samples after processing multiple ingredients together. In Korea, TDSs have been conducted to estimate dietary intakes of heavy metals, pesticides, mycotoxins, persistent organic pollutants, and processing contaminants. TDSs need to be carried out periodically to ensure food safety.

A Collaborative Study to Establish a Korea National Biological Standard for Antithrombin III Concentrate

  • Kang, Hye-Na;Oh, Ho-Jung;Kim, Soon-Nam;Hong, Choong-Man;Lee, Ki-Hong;Yoo, Si-Hyung;Shin, In-Soo;Choi, Seung-Eun;Lee, Seok-Ho
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.149.2-149.2
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    • 2003
  • We have carried out a collaborative study to evaluate a candidate preparation of antithrombin III concentrate whether it is suitable to serve as a Korea National Biological Standard. Three National Control Laboratories and three manufacturers participated in this study. The potency of this candidate preparation was determined by using a heparin cofactor chromogenic method described in the Minimum Requirements for Biological Products and the European Phamacopoeia. (omitted)

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