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Biokinetics of Carbohydrate and Lipid Metabolism in Normal Laying Hen -II. Incorporation of Activity in Plasma Lipid After Injection of Glucose-U-$C^{14}$- (정상산란계(正常産卵鷄)에 있어서 탄수화물(炭水化物)과 지질대사(脂質代謝)의 생동역학(生動力學) -제2보(第二報) 방사능(放射能)$(C^{14})$포도당 주사후(注射後) 혈장(血漿) 지질(脂質)로의 방사능(放射能)의 병합(倂合)-)

  • Chiang, Y.H.;Riis, P.M.
    • Applied Biological Chemistry
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    • v.21 no.1
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    • pp.63-67
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    • 1978
  • The incorporation of activity in plasma lipid was determined after injection of $u-C^{14}-glucose$ to normal laying hen. The extraction of total lipid from plasma was carried out by the method of Floch et al. with some modifications. The counting of carbon-14 activity was conducted by a Beckman Liquid Scintillation System, The concentration of plasma lipid was estimated as much as 3,070mg per 100ml of plasma taken at 5 minutes after injection of tracer amount of $u-C^{14}-glucose$. The specific activity per gram of plasma lipid carbon atom per injected dose per kg body weight increased gradually following the time after injection until 120 minutes, whereas the glucose activity decreased logarithmically. The partial incorporation quotient of activity in plasma lipid from that of glucose was 0.73% until 120 minutes after the injection.

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The Site-Directed A184S Mutation in the HTH Domain of the Global Regulator IrrE Enhances Deinococcus radiodurans R1 Tolerance to UV Radiation and MMC Shock

  • Zhang, Chen;Zhou, Zhengfu;Zhang, Wei;Chen, Zhen;Song, Yuan;Lu, Wei;Lin, Min;Chen, Ming
    • Journal of Microbiology and Biotechnology
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    • v.25 no.12
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    • pp.2125-2134
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    • 2015
  • IrrE is a highly conserved global regulator in the Deinococcus genus and contributes to survival from high doses of UV radiation, ionizing radiation, and desiccation. Drad-IrrE and Dgob-IrrE from Deinococcus radiodurans and Deinococcus gobiensis I-0 each share 66% sequence identity. However, Dgob-IrrE showed a stronger protection phenotype against UV radiation than Drad-IrrE in the D. radiodurans irrE-deletion mutant (ΔirrE), which may be due to amino acid residues differences around the DNA-binding HTH domain. Site-directed mutagenesis was used to generate a Drad-IrrE A184S single mutant, which has been characterized and compared with the ΔirrE mutant complemented strain with Drad-irrE, designated ΔirrE-E. The effects of the A184S mutation following UV radiation and mitomycin C (MMC) shock were determined. The A184S mutant displayed significantly increased resistance to UV radiation and MMC shock. The corresponding A184 site in Dgob-IrrE was inversely mutated, generating the S131A mutant, which exhibited a loss of resistance against UV radiation, MMC shock, and desiccation. qPCR analysis revealed that critical genes in the DNA repair system, such as recA, pprA, uvrA, and ddrB, were remarkably induced after UV radiation and MMC shock in the ΔirrE-IE and A184S mutants. These data suggested that A184S improves the ability against UV radiation and MMC shock, providing new insights into the modification of IrrE. We speculated that the serine residue may determine the efficiency of DNA binding, leading to the increased expression of IrrE-dependent genes important for protection against DNA damage.

Effect of Artificially Decreased Visual Acuity upon Eye-Hand Coordination using Lee-Ryan Eye-Hand Coordination Test (Lee-Ryan Eye-Hand Coordination Test를 이용한 인위적 시력저하가 눈-손 협응능력에 미치는 영향)

  • Lee, Ki-Seok
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.3
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    • pp.371-376
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    • 2014
  • Purpose: The aim of this study was to explore the effect of artificially decreased eye in normal vision on eye-hand coordination (EHC) when using the Lee-Ryan Eye-Hand Coordination Test recently reported. Methods: Eleven adults with normal vision aged $29.46{\pm}5.94$ years participated for this study where a non-dominant eye artificially induced moderate refractive amblyopic vision at near by adding a plus lens conducted EHC tasks and then did the test again under normal vision following 2 weeks. To investigate the ability of EHC, 7 tasks including individually different level of difficulty in the Lee-Ryan EHC Test were selected to compare and analyze EHC in terms of two independent variables such as time taken and the number of errors. Results: In time taken, subjects with artificially decreased vision took more time than normal vision under monocular conditions (p=0.013), while those with the decreased vision completed their tasks faster than normal vision under binocular conditions (p=0.001). In the number of errors, subjects with the decreased vision made more mistakes (p<0.001) as shown in time taken, whereas there was no difference between monocular and binocular viewing conditions in the decreased vision. Conclusions: Unlike previous EHC tests including limitations for application, deficit in EHC can be screened by the Lee-Ryan EHC Test developed based on simple computer-based system. Therefore, it is considered that further studies relevant to deficits in visual function such as amblyopia will be carried out in clinics as well as research.

Muscle Activities in the Lower Limbs for the Different Movement Patterns on an Unstable Platform

  • Piao, Yong-Jun;Choi, Youn-Jung;Kwon, Tae-Kyu;Hwang, Ji-Hye;Kim, Jung-Ja;Kim, Dong-Wook;Kim, Nam-Gyun
    • Journal of Biomedical Engineering Research
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    • v.28 no.5
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    • pp.590-600
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    • 2007
  • We performed experimental studies on the muscle activities in the lower limbs for the different movement patterns on an unstable platform. A training system for postural control using an unstable platform that we previously developed was applied for the experiments. This unstable platform provides 360 degrees of movement allowing for training of posture in various directions and provides simultaneous excitations to visual sensory, somatic sensation and vestibular organs. Compare with the stable platform, keeping body balance on the unstable platform requests more effective sensation from vision, vestibular sense and somatic sense. Especially, the somatosensory inputs from the muscle proprioceptors and muscle force are crucial. To study the muscle activities for the different movement patterns and find the best training method for improving the ability of postural control through training and improving the lower extremity muscular strength, fifteen young healthy participants went through trainings and experiments. The participants were instructed to move the center of pressure following the appointed movement pattern while standing on the unstable platform. The electromyographies of the muscles in the lower limbs were recorded and analyzed in the time and the frequency domain. Our experimental results showed the significant differences in muscle activities for the different movement patterns. Especially, the spectral energy of electromyography signals in muscle for the movement pattern in anterior-posterior direction was significantly higher than those occurred in the other patterns. The muscles in the lower leg, especially tibialis anterior and gastrocnemius were more activated compared to the others for controlling the balance of body on the unstable platform. The experimental results suggest that, through the choice of different movement pattern, the training for lower extremity strength could be performed on specific muscles in different intensity. And, the ability of postural control could be improved by the training for lower extremity strength.

An Analysis of Trends in Quantitative Studies on Female North Korean Refugees (탈북여성 관련 양적 연구동향 분석)

  • Lee, Soon Min;Shim, Woochan
    • The Journal of the Korea Contents Association
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    • v.18 no.7
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    • pp.470-483
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    • 2018
  • This study was conducted to analyze the trend of quantitative research regarding female North Korean refugees in order to broaden our understanding of North Korean women and provide directions for future research. In August 2017, the Korean studies Information Service System (KISS) and Nuri Media (DBpia) databases were used to search academic peer reviewed journal articles with the following keywords: "North Korean female", "North Korean female refugees" and "North Korean female defectors". Trend analysis included a content analysis of the study finding section, along with analysis of the general characteristics of the study such as published journals, year of publication, study methodologies, and subject of the study. The main findings are as follows: First, Korean Journal of Woman Psychology was the journal with the most studies on female North Korean refugees. Second, as a result of looking at research trends by year, there was only one study on North Korean female refugees published between 2000 and 2004, and the number started to increase in 2010(8 articles, 22.22%). Third, according to the analysis of research trends by research methods, survey method was most frequently used. Fourth, statistical analysis was most often utilized analysis methodology(34 studies, 94.44%). Fifth, in the content analysis, North Korean female refugees' mental health and emotional issues(17 studies, 47.22%) were the most often the focus of studies being analyzed, followed by social adjustment issues((5 studies, 13.89%). Based on these results, directions for future studies were suggested.

Attacking OpenSSL Shared Library Using Code Injection (코드 주입을 통한 OpenSSL 공유 라이브러리의 보안 취약점 공격)

  • Ahn, Woo-Hyun;Kim, Hyung-Su
    • Journal of KIISE:Computer Systems and Theory
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    • v.37 no.4
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    • pp.226-238
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    • 2010
  • OpenSSL is an open-source library implementing SSL that is a secure communication protocol. However, the library has a severe vulnerability that its security information can be easily exposed to malicious software when the library is used in a form of shared library on Linux and UNIX operating systems. We propose a scheme to attack the vulnerability of the OpenSSL library. The scheme injects codes into a running client program to execute the following attacks on the vulnerability in a SSL handshake. First, when a client sends a server a list of cryptographic algorithms that the client is willing to support, our scheme replaces all algorithms in the list with a specific algorithm. Such a replacement causes the server to select the specific algorithm. Second, the scheme steals a key for data encryption and decryption when the key is generated. Then the key is sent to an outside attacker. After that, the outside attacker decrypts encrypted data that has been transmitted between the client and the server, using the specified algorithm and the key. To show that our scheme is realizable, we perform an experiment of collecting encrypted login data that an ftp client using the OpenSSL shared library sends its server and then decrypting the login data.

A Study on the Causes That Have Influence over the Effect of PPL in the Game (게임 속 PPL의 효과에 영향을 미치는 요인에 관한 연구)

  • Kim, Young-Rak;Cho, Youn-Gon;Choi, Gui-Young
    • Journal of Korea Multimedia Society
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    • v.13 no.8
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    • pp.1256-1262
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    • 2010
  • The game has been rapidly evolving through various media such as computer, console game machine, cellular phone and PMP based on the advanced development of scientific technology. In terms of demand, the interest in and desire to consume the game as a way of spending people's spare time have been on the increase constantly while the level of income has been improved. Eventually, the game has gradually expanded its scope of supply and demand, has established its own status as one of the media that is scientifically-intensive and has been developed into a game industry, a large-scale industry. Unlike image media, the methods of exposure in PPL are varied in accordance with the genre of games. This study divides the causes that have influence over the effect of PPL in the game into the genre of game and the skill of gamer. The results of the experiment on how much the aforementioned two elements have influence over the effect of PPL are as in the following: It has been demonstrated that the effect of PPL could appear different according to the genre of game and the skill of gamer on the game. Besides, the genre of game that is dynamic in its screen change in the game has relatively lower effect of PPL than that is not dynamic. Meanwhile, the persons who are highly skilled in the game have higher degree of recognition and preference to the inserted PPL than those who are lowly skilled. In this regard, it has given us a theoretical ground that the fees system for PPL ads should be established variously in accordance with the genre of game and the level of online game users.

The Effect of Career Self-efficacy on the Course of Retirement for Baby Boomer Generation (베이비부머 세대의 진로자기효능감이 은퇴경로에 미치는 영향)

  • Kim, Ki-Seung;Yun, Sung-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.4
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    • pp.1585-1593
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    • 2012
  • Year 2010 was the first year in which the baby boomer generation began to regularly retire by the corporate retirement system. For the following 10 years from then, large scale retirement of the baby boomer generation that used to be the driving force of economic growth in Korean society is expected to cause various social problems such as reduction in labor force and economic loss from transfer to welfare subjects. In relation to reemployment of the baby boomer generation after retirement, this study was attempted first, for analysis on the difference in the course of retirement according to average monthly income and current occupation and second, with an assumption that career self efficacy will influence the course of retirement. Total of 500 surveys for this study were distributed to baby boomer generations through direct visit or mail post in Seoul, Gyeonggi, Gangwon, Chungnam, Gyeongnam, Jeonnam and Jeju for one month during January 17 and February 16, 2012. 443 surveys were returned, among which 400 effective responses were selected as study subjects. As a result, the course of retirement according to average monthly income was verified to be significant for all factors. Significant results were found for the course of retirement according to current occupation in job transfer, complete non-employment and repetitive non-employment. In relation to the effect of career self efficacy on the course of retirement, job movement factor was affected by 21%. This study will be a good guide for the establishment of a social policy and retirement life preparation of the baby boomer generation.

The study on the height standard and the slenderness ratio according to location types of Mixed-use Residential Tall buildings (초고층 주상복합건축물 입지유형에 따른 높이기준 및 세장비 제안에 관한 연구)

  • Sung, Lee-Yong;Kim, Yun-Jun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.6
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    • pp.2779-2788
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    • 2012
  • The housing market is now difficult because of excess of the increase rate of housing and long-term recession but high-rise mixed-use buildings can mix residential facilities with various demand facilities focusing and they have the advantages to secure open space and excellent view by high-rise apartment. But there are problems by hindrance of skyline formation and height of buildings. Therefore, the purpose of this study is to suggest the height standard and the slenderness ratio to location types of Mixed-use Residential Tall buildings. For the method of the study, term arrangement through literature search and the precedent research survey were first done, the level of urban design and the details related to the height of buildings were done as the case research focusing on the 16 cases in Seoul. The following results were drawn by suggesting the height standard and the slenderness ratio by location type based on them. First, the height of mixed-use building by location type in the level of urban design gets higher starting from the secondary center of the city and can be suggested as from less than 150m to more than 200m. Second, the slenderness ratio shall be planned as more than 1:3 because the area of the ground level of mixed-use building is large unlike Mixed-use Residential Tall buildings and visual passage shall be placed so that unity of openness and group formation will be planned. Third, for the height related to Mixed-use Residential Tall buildings, amendment of the special architectural district system and the special law related to super high-rise buildings shall be enacted.

The Use Intention of Mobile Travel Apps by Korea-Visiting Chinese Tourists (방한 중국 관광객의 모바일 여행 앱 이용의도에 관한 연구)

  • Wu, Runze;Lee, Jong-Ho
    • Journal of Distribution Science
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    • v.15 no.5
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    • pp.53-64
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    • 2017
  • Purpose - This study focuses on use intention of mobile travel Apps by Chinese tourists visiting Korea based on UTAUT model, ISS model and ITM model. And the corresponding market promotion schemes are proposed for operators of mobile travel Apps by the research results. Research design, data, and methodology - After collecting 326 respondents in China with cross-sectional questionnaires, this study begins the empirical research with users of mobile travel Apps, and analyzes data with IBM SPSS 23.0 and IBM AMOS 23.0. Results - The results of this study include the following aspects: firstly, the System quality and Information quality are accepted for hypotheses of Satisfaction and Performance expectancy. Secondly, the Personal Propensity to Trust and Firm Reputation are accepted for Initial Trust hypothesis, and the hypotheses of Firm Reputation and Initial Trust are accepted for Use Intention. Thirdly, the Performance expectancy, Effort expectancy, Social influence are accepted for Use Intention hypothesis. Conclusions - With the increase of tourists visiting Korea, it can be predicted that the needs visiting Korea will be increased persistently for Chinese - this trend brings about the increase of the Chinese travel. First, information quality greatly influences satisfaction and performance expectancy. The research result shows that, the higher the mobile traveling App's information quality is, the higher the satisfaction and performance expectancy will be. Therefore, operators of mobile traveling App should have in-depth investigations towards users, to know the latter's real demand to the information quality and then provide corresponding services. Second, performance expectancy and effort expectancy greatly influence users' intention. Therefore, mobile traveling App operators should improve Apps' convenience and efficiency and, in doing so, find an effective method for market expansion. Third, social influence greatly affects users' intention. The result shows that mobile traveling App operators should pay attention to the influence of mass media and friends' recommendation on users, thereby it is necessary to improve advertisement activities. Fourth, initial trust also influences users' intention. The result shows that initial trust is a key element inducing users to generate use intention. Therefore, mobile traveling Apps operators should make efforts to catch elements that influence users' initial trust.