• Title/Summary/Keyword: following system

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Effect of GE-132 on the Hepatic Bromobenzene Metabolizing Enzyme System in Rats (유기게르마늄(GE-132)이 Bromobenzene의 대사계에 미치는 영향)

  • 김석환;조태현;최종원
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.6
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    • pp.702-708
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    • 1993
  • The study was attempted to elucidate the mechanism of GE-132(100mg/kg, p.o. for 6 weeks) on the metabolism of bromobenzene (460mg/kg, i.p. bid, for 2 days), which has potent carcinogenicity, mutagenicity and hepatotoxicity. It showed that activities of cytochrome p-450, aminopyrine demethylase and aniline hydroxylase, which have epoxide generating property, were not changed by GE-132 treatment. On the other hand, epoxide hydrolase was not changed but that glutathione S-transferase was significantly increased by GE-132 treatment. And also ${\gamma}-glutamylcysteine$ synthetase was not changed following the GE-132 treatment, but the activity of glutathione reductase was significantly increased. The level of hepatic glutathione which was decreased by bromobenzene recovered markedly by GE-132 pretreatment. It is concluded that the mechanism for the observed effect of GE-132 on bromobenzene metabolism is due to the induction of glutathione S-transferase.

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Removal of Rhodamine B Dye Using a Water Plasma Process (수중 플라즈마 공정을 이용한 Rhodamine B 염료의 제거)

  • Kim, Dong-Seog;Park, Young-Seek
    • Journal of Environmental Health Sciences
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    • v.37 no.3
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    • pp.218-225
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    • 2011
  • Objectives: In this paper, a dielectric barrier discharge (DBD) plasma reactor was investigated for degrading the dye Rhodamine B (RhB) in aqueous solutions. Methods: The DBD plasma reactor system in this study consisted of a plasma component [titanium discharge (inner), ground (outer) electrode and quartz dielectric tube], power source, and gas supply. The effects of various parameters such as first voltage (input power), gas flow rate, second voltage (output power), conductivity and pH were investigated. Results: Experimental results showed that a 99% aqueous solution of 20 mg/l Rhodamine B is decolorized following an eleven minute plasma treatment. When comparing the performance of electrolysis and plasma treatment, the RhB degradation of the plasma process was higher that of the electrolysis. The optimum first voltage and air flow rate were 160 V (voltage of trans is 15 kV) and 3 l/min, respectively. With increased second voltage (4 kV to 15 kV), RhB degradation was increased. The higher the pH and the lower conductivity, the more Rhodamine B degradation was observed. Conclusions: OH radical generation of dielectric plasma process was identified by degradation of N, N-dimethyl-4-nitrosoaniline (RNO, indicator of OH radical generation). It was observed that the effect of UV light, which was generated as streamer discharge, on Rhodamine B degradation was not high. Rhodamine B removal was influenced by real second voltage regardless of initial first and second voltage. The effects of pH and conductivity were not high on the Rhodamine B degradation.

Anti-inflammatory Effects of Gastrodia elata Extract in Lipopolysaccharide-stimulated BV-2 Microglia Cell

  • Heo, Young Hyun;Choi, Na Hyun;Seo, Young Kyung;Jang, Ji Yeon;Lee, Jun Hyuk;Kim, Jae Kyu;Choi, Byung Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.738-744
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    • 2012
  • Gastrodia elata Blume is used for a variety of purposes including treatment of inflammation in the Korean medicine. The present study investigated whether the G. elata extracts have the anti-inflammatory effect on lipopolysaccharide(LPS)-stimulated BV-2 microglia cells. G. elata extracts showed an anti-inflammatory effects in the morphological and nitric oxide(NO) analysis, especially in hexane extract. So we investigated the hexane extract from G. elata in the following experiments. Hexane extract significantly inhibited the secretion of NO with protein level of inducible nitric oxide synthase in LPS-stimulated BV2 microglia cells. Hexane extract also inhibited LPS-stimulated inflammatory responses involving the degradation of cytosolic inhibitory(I)-${\kappa}B{\alpha}$ and the translocation of nuclear factor(NF)-${\kappa}Bp65$ to nucleus in LPS-stimulated BV-2 microglia cells by morphological analysis. Western blot analyse confirmed that I-${\kappa}B{\alpha}$ and NF-${\kappa}Bp65$ showed a similar pattern as morphological analysis. Our results suggest that G. elata extracts, especially hexane extract, may act as a therapeutic agent for inflammatory disease in the central nervous system through a selective regulation of NO production and NF-${\kappa}B$ activation.

A Study on the Reference Evaluation Applying Conjoint Analysis of the Marketing Research (마케팅조사의 결합분석법을 활용한 참고봉사의 평가에 관한 연구)

  • Bae Soon Ja
    • Journal of the Korean Society for Library and Information Science
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    • v.21
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    • pp.141-168
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    • 1991
  • The Purpose of this study is to explore and analyse ways of enhancing the effectiveness of reference service through reference evaluation. Marketing research technique combined with pre-evaluation theory was applied in this study to find out information for practice the service based on current concept of reference service. Aims and results of this study can be summarised as follows: First, the evaluation of effectiveness of reference service should be conducted for the purpose of finding out the ways of increasing user's satisfaction. Second, the policy evaluation was understood as the appropriated evaluation concept. The policy evaluation in principle coincides with reference service in sense that the satisfaction of public should have priority and hence be the criterion of the evaluation. Third, marketing research based on recently developed 'marketing concept', which concentrates all its efforts to meet user's demand and attempt to acquire the information for better marketing management of non-profit organization such as library, is examined to find out the evaluation method practically applicable to the pre-evaluation of reference service. In this study , conjoint analysis was adopted as the method of pre-evaluation about reference service. The Reference Room of the Central Library Yonsei University, was selected as the arget sample to find out the expected condition for the maximization of the user's satisfaction from the reference service. Based on this example study, the analysis indicates as the most desirable combination for reference service in terms of the user's satisfaction is following condition: the younger librarian with aimable personality who displays willingness In his/her assistance, plus as the method of reference service, sufficient and practical introduction to the reference materials available, plus immediate and satisfactory result of the service, and finally a library equipped with inter-library use system.

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Thermal Hazards of Polystyrene Polymerization Process by Bulk Polymerization (벌크 중합법에 의한 폴리스티렌 중합공정의 열적위험성)

  • Han, In-Soo;Lee, Jung-Suk;Lee, Keun-Won
    • Journal of the Korean Institute of Gas
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    • v.17 no.4
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    • pp.1-8
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    • 2013
  • The aim of this study is to assess thermal hazards of polystyrene polymerization process by bulk polymerization with accelerating rate calorimeter(ARC) and Multimax reactor system(MM). From this study, we found out that the polymerization process should be operated at reaction temperature of $120^{\circ}C{\sim}130^{\circ}C$. At reaction temperature over $130^{\circ}C$, there was a runaway reaction hazard due to the temperature control failure following a viscosity increase of reaction products. With a cooling failure of a reactor in the early stage of process operation at the reaction temperature ($120^{\circ}C{\sim}130^{\circ}C$), there was a high thermal hazard of burst of a reactor's rupture disk or explosion of a reactor caused by the rapid rise of temperature and pressure to $340^{\circ}C$, 5.3 bar respectively within 30 - 50 minutes.

A Study on Color Images and Emotional Evaluation of Them in University Library - Focusing on the Survey of the Situation of the H University Library - (대학도서관에서의 색채이미지와 감성평가 연구 - H대학교 도서관의 현황조사를 중심으로 -)

  • Ham, Yu-Jin;Oh, Young-Keun
    • Korean Institute of Interior Design Journal
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    • v.24 no.5
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    • pp.42-50
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    • 2015
  • In the 21st century, university library is changing into a new paradigm. Among others, color image emerges as an important aspect of the library. Up to now, studies on colors of indoor space have been limited on partial and specific spaces. But, this study, using the tool of emotional evaluation, aims to do a comprehensive research on color image of the whole space. This research uses the H University library completed in March 2015. This research is performed in the following procedure. First, previous related researches for the past ten years from 2005 to 2015 is examined, which will help understand the trends in this kind of research, and set up the concrete goal of research. By literature review, color image is established in the environmental psychological aspect. Second, to analyze colors, all the spaces of the library from the entrance lobby are filmed. Filmed images are changed into mosaic, and color palettes are composed, and color values are calculated using the Munsell color system. Third, emotional words are extracted, and emotional evaluation is made. Using the Semantic Differential scale method, emotional differences among subjects are compared, and the validity of the survey data is tested using the statistical program SPSS 18.0. As the outcome of the research shows, the color image and emotion in space are closely related. And, through emotion, it is possible to get color image, and this aspect can be scholastically systemized and developed.

A Study of node Authentication in Ad-hoc Network using Java Card (자바 카드를 이용한 Ad-hoc망의 노드 인증에 관한 연구)

  • Lee, Cheol-Seung;Shin, Myeong-Sook;Lee, Joon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.1
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    • pp.902-905
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    • 2005
  • In this paper we challenge the mobile node Authentication using Java Card authentication protocol in Ad-hoc network environment. Ad-hoc network is a collection of wireless mobile nodes without the support of a stationary infrastructure. and DSR routing protocol, which is one of famous mobile ad-hoc rooting protocols, has the following network path problem. this paper is the security structure that defined in a mobile network and security and watches all kinds of password related technology related to the existing authentication system. It looks up weakness point on security with a problem on the design that uses Ad-hoc based structure and transmission hierarchical security back of a mobile network, and a server-client holds for user authentication of an application level all and all, and it provides one counterproposal. Java Card Authentication of mobile node can possibly be applied to the area of M-Commerce, Wireless Security, and Ubiquitous Computing and so on.

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A Study on Architectural Type and Design Characteristics of Floating Architecture (플로팅건축의 유형 및 디자인 특성에 관한 연구)

  • Pak, Sung-Sine
    • Journal of Navigation and Port Research
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    • v.35 no.5
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    • pp.407-414
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    • 2011
  • Floating architecture is the most effective way to accommodate itself to sea-level rise due to climate change. At the same time floating architecture is the best model to offer the new spatial experience through water-friendly environment. Domestic floating architecture is still on the early stage compared to Europe which has several companies specialized in designing and building floating architecture. Floating architecture is divided into 8 types according to its criteria such as program, form, scale, level, location, access, mobility and energy. The following are design characteristics of floating architecture : (1) composed of 2 stories, (2) having large deck, (3) designing rectangular plan and balanced mass, (4) maximizing view, (5) having water-friendly space, (6) multi-using space and minimizing surface, (7) planning section to control light reflecting from the water, (8) modular and unit system.

Influence of modeling agents on the surface properties of an esthetic nano-hybrid composite

  • Kutuk, Zeynep Bilge;Erden, Ecem;Aksahin, Damla Lara;Durak, Zeynep Elif;Dulda, Alp Can
    • Restorative Dentistry and Endodontics
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    • v.45 no.2
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    • pp.13.1-13.10
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    • 2020
  • Objective: The aim of this study was to evaluate the influence of different modeling agents on the surface microhardness (Vickers hardness number; VHN), roughness (Ra), and color change (ΔE) of a nano-hybrid composite with or without exposure to discoloration by coffee. Materials and Methods: Sixty-four cylinder-shaped nano-hybrid composite specimens were prepared using a Teflon mold. The specimens' surfaces were prepared according to the following groups: group 1, no modeling agent; group 2, Modeling Liquid; group 3, a universal adhesive (G-Premio Bond); and group 4, the first step of a 2-step self-adhesive system (OptiBond XTR). Specimens were randomly allocated into 2 groups (n = 8) according to the storage medium (distilled water or coffee). VHN, Ra, and ΔE were measured at 24 hours, 1 week, and 6 weeks. The Kruskal-Wallis test followed by the Bonferroni correction for pairwise comparisons was used for statistical analysis (α = 0.05). Results: Storage time did not influence the VHN of the nano-hybrid composite in any group (p > 0.05). OptiBond XTR Primer application affected the VHN negatively in all investigated storage medium and time conditions (p < 0.05). Modeling Liquid application yielded improved Ra values for the specimens stored in coffee at each time point (p < 0.05). Modeling Liquid application was associated with the lowest ΔE values in all investigated storage medium and time conditions (p < 0.05). Conclusion: Different types of modeling agents could affect the surface properties and discoloration of nano-hybrid composites.

A Study on the Recognition of Polyhedral Object using 3-D Information (3차원 정보를 이용한 다면체의 물제인식에 관한 연구)

  • 김영일;우동임;백남칠;우광방
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.38 no.6
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    • pp.458-469
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    • 1989
  • A measurement method is proposed which finds 3-D position and attitude of a known polyhedra utilizing shading information. Through the systematic interpretation of relations between polyhedra and its image as well as shadow image and also the determination of candidate position, 3-D information with respect to vertex of polyhedra is extracted. Following preprocessing of this information, the image of polyhedra is represented in terms of the scene with positioned object and the correspondence is searched by means of matching process between a scene description of the object and the correspondence is searched by means of matching process between a scene description of the object and a model description stored in data-base. In the experiments, initially 3-D information is employed to select several model regions, and objects are recognized through matching process with respect to scene regions. The results demonstrate that the recognition system performs with a high efficiency by proper selection of the threshold values.