• Korean Institute of Interior Design Journal
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• v.16 no.2 s.61
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• pp.97-104
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• 2007

At a time of emphasized need for user-oriented design, methods such as Post Occupancy Evaluation are being used to measure the exact demands of the users. The conventional methods, however, have mostly been conducted based on questionnaires printed on paper, which has posed numerous problems in researches designed to measure the visual demands. Along with the continued development of the internet and computer media, there have been examples of interactive media applications as a means of improving the existing paper-based research methods. This study is a follow-up to the primary study that unveiled cautious variances of the media. 200 samples of media-based researches were extracted to be used in analysis of in-depth visual demands. 200 housewives from rural Iud development zones, who exercises the most influence in household purchases in these regions where the problem of rate of distribution Is coming under the limelight, were chosen as the subjects. The subjects were selected from land development zones of Gimhae-si and Haeundae. At first, the research was prepared as a web-based endeavor but it employed direct research of field personnel in consideration of that this research is in the beginning. This follow-up study deals mainly with the visual demands for which cautious variances were detected in the primary study and includes analysis of mainly ground Plan layout, space coloration, livingroom utilization, and vlsual composition of LDK. Media research had the advantage of zero rate of questionnaire error due to a pre-programmed search routine, and it was possible to ascertain the actual trade-off basis demands of the residents in terms of ground plan layout. In addition, whereas conventional research methods based on still images were susceptible to the preconceptions of the respondents, the interactive media allowed for easy understanding of the spatial layout and thus made it possible for all respondents to provide answers under the same conditions.

• Journal of Korean Neurosurgical Society
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• v.58 no.6
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• pp.504-507
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• 2015

Objective : Our aim was to evaluate the histopathological effects of tissue adhesives on peripheral nerve regeneration after experimental sciatic nerve transection in rats and to search whether these tissue adhesives may possess a therapeutic potential in peripheral nerve injuries. Methods : This experimental study was performed using 42 female Wistar-Albino rats distributed in 6 groups subsequent to transection of right sciatic nerves. Group I underwent external circumferential neurolysis; Group II received suture repair; Group III had local polymeric hydrogel based tissue adhesive administration; Group IV received suture repair and polymeric hydrogel based tissue adhesive application together; Group V had gelatin based tissue adhesive application and Group VI had suture repair and gelatin based tissue adhesive together. After a 6-week follow-up period, biopsies were obtained from site of neural injury and groups were compared with respect to histopathological scoring based on inflammatory, degenerative, necrotic and fibrotic changes. Results : There were remarkable differences between control group and study groups with respect to inflammation (p=0.001), degeneration (p=0.002), necrosis (p=0.007), fibrosis (p<0.001) and vascularity (p=0.001). Histopathological scores were similar between study groups and the only noteworthy difference was that Group V displayed a lower score for necrosis and higher score in terms of vascularization. Conclusion : Our results imply that tissue adhesives can be useful in repair of peripheral nerve injuries by decreasing the surgical trauma and shortening the duration of intervention. Results with gelatin based tissue adhesive are especially promising since more intense vascularity was observed in tissue after application. However, trials on larger series with longer durations of follow-up are essential for reaching more reliable conclusions.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8383-8386
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• 2016

Background: To evaluate the safety, convenience and effectiveness of 940nm diode laser for treatment of homogenous leukoplakia. Materials and Methods: Ten patients having homogenous leukoplakia which were diagnosed clinically were selected from an Indian dental educational institution for the study. Toludine blue staining was applied locally over the lesion. The area where there was increased uptake of stain was excised using a 940 nm EZLASE TM diode laser (BIOLASE-USA). Results: Although various treatment modalities have been tried and the search continues for novel treatment modalities for complete removal of homogenous leukoplakia, from results of our preliminary pilot study it is clear that the use of 940 nm diode laser as a treatment modality for homogenous leukoplakia is a good substitute. Healing was perfect without any complication within a duration of 1 month. Pain intensity was also mild and absolutely zero on the VAS scale after 1 month follow up. Conclusions: 940 nm diode lasers are safe and can be effectively used as a treatment modality of homogenous leukoplakia, without any complication and without compromising health and oral function of patients. Considering recurrence factor, long term follow up for patients is a must.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4691-4698
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• 2015

Background: The tumor suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. However, available results for the prognostic value of PTEN expression in patients with cancer remain controversial. Therefore, a meta-analysis of published studies investigating this issue was performed. Materials and Methods: A literature search via PubMed and EMBASE databases was conducted. Statistical analysis was performed by using the STATA 12.0 (STATA Corp., College, TX). Data from eligible studies were extracted and included into the meta-analysis using a random effects model. Results: A total of 3,810 patients from 27 studies were included in the meta-analysis, 22 investigating the relationship between PTEN expression and overall survival (OS) using univariate analysis, and nine with multivariate analysis. The pooled hazard ratio (HR) for OS was 1.64 (95% confidence interval (CI): 1.32-2.05) by univariate analysis and 1.56 (95% CI: 1.20-2.03) by multivariate analysis. In addition, eight papers including two disease-free-survival analyses (DFSs), four relapse-free-survival analyses (RFSs), three progression-free-survival analyses (PFSs) and one metastasis-free-survival analysis (MFS) reported the effect of PTEN on survival. The results showed that loss of PTEN expression was significant correlated with poor prognosis, with a combined HR of 1.74 (95% CI: 1.24-2.44). Furthermore, in the stratified analysis by the year of publication, ethnicity, cancer type, method, cut-off value, median follow-up time and neoadjuvant therapy in which the study was conducted, we found that the ethnicity, cancer type, method, median follow-up time and neoadjuvant therapy are associated with prognosis. Conclusions: Our study shows that negative or loss of expression of PTEN is associated with worse prognosis in patients with cancer. However, adequately designed prospective studies need to be performed for confirmation.

• Clinics in Shoulder and Elbow
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• v.21 no.3
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• pp.120-126
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• 2018

Background: Treatment of distal humerus fractures in osteoporotic elderly patients is often challenging. For non-reconstructible fractures with open reduction and internal fixation, total elbow arthroplasty (TEA) is an acceptable alternative. However, the relatively high complication rates and lifelong activity restrictions make TEA less ideal for elderly or low-demand patients. Efforts to identify or develop alternate procedures that benefit relatively young, high-demand patients have resulted in increased interest in hemiarthroplasty. This systematic review reports the clinical outcomes of hemiarthroplasty for distal humeral fractures. Methods: We systematically reviewed the databases of PubMed, Ovid MEDLINE, and Cochrane Library. All English-language studies published before June 2017 were considered for possible inclusion. Search terms included 'distal humerus fracture' and 'hemiarthroplasty'. Studies reporting outcomes (and a minimum of 1 year clinical follow-up) in human subjects after hemiarthroplasty (Latitude system) for distal humeral fractures were assessed for inclusion. Patient demographics, clinical and radiographic outcomes, and complications were recorded, and homogenous outcome measures were analyzed. Results: Nine studies with a total of 115 patients met the inclusion criteria. Among the included studies, the weighted mean follow-up time was 35.4 months. Furthermore, the weighted mean of the postoperative range of motion ($107.6^{\circ}$ flexion-extension, $157.5^{\circ}$ for pronation-supination) and functional outcomes (Mayo elbow performance scores: 85.8, Disabilities of the Arm, Shoulder and Hand score: 19.6) were within the acceptable range. Conclusions: Our study indicates that hemiarthroplasty is a viable option for comminuted distal humerus fracture. Satisfactory functional outcomes were observed in most patients.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.122.2-122.2
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• 2011

For more than a decade, NEA (Near-Earth Asteroid) survey teams equipped with 1 meter-class telescopes discovered thousands of NEAs in the northern sky. As of August 2011, some 8,200 NEAs have been cataloged, yet only five percent of them has been investigated for their physical and chemical properties. In order to improve current situation, we propose a deep ecliptic survey utilizing KMTNet, for detection and characterization of NEAs in the southern sky. Thanks to the wide-field capability (four square degrees) of the telescopes, we will be able to considerably expand the search volume carrying out precision photometry down to 21.5th magnitude. We plan to focus our survey on opposition and two "sweet spots" in the ecliptic belt. Since SDSS colors characterize mineralogical properties of NEAs, g', r', i', z' filters will be employed. Based on the round-the-clock observation, we will study their rotational properties; for multiple systems, mass, density and other physical parameters can be obtained. We plan to maintain a dedicated database of the physical and mineralogical properties of NEAs. With this archive, it is expected that our understanding on the population will see a drastic change. We also plan to participate in the GAIA Follow-Up Network for ground based observation of the Solar System Objects (GAIA-FUN-SSO). The follow- up astrometry will be performed upon alerts issued by the GAIA-FUN-SSO Central Node in France.

• Journal of Korean Institute of Industrial Engineers
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• v.43 no.2
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• pp.127-134
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• 2017

For product or process design and development, it is common to optimize multiple responses (characteristics) based on experimental data. To determine optimal conditions, we need to design the experiment, estimate a proper model for each response, and optimize the multiple responses simultaneously. There are several techniques and many research results on optimizing multiple responses simultaneously, when the experimental data are available. However, the experimental design issue for optimizing multiple responses has not been discussed yet. This paper proposes some idea on how to plan screening design when requirements for multiple performance characteristics are to be met in developing new products. A screening design procedure is developed for securing the requirements of multiple responses. Initial design factors are classified into three categories; specific, non-conflicting common, and conflicting common. After screening experiments, follow-up design region search method is suggested with respect to the most unsatisfied or important response, or overall desirability. A case study on a synthesis of melamine formaldehyde resin is presented to illustrate the procedure and to show the validity of the approach.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.61.3-61.3
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• 2019

We report the status of KMTNet (Korea Microlensing Telescope Network) microlensing. From KMTNet event-finder, we are annually detecting over 2500 microlensing events. In 2018, we have carried out a real-time alert for only the Northern bulge fields. It was very helpful to select Spitzer targets. Thanks to the real-time alert, KMT-only events for which OGLE and MOA could not detect have been largely increased. The KMTNet event-finder and alert-finder algorithms are being upgraded every year. From these, we found 18 exoplanets and various interesting events, such as an exomoon-candidate, a free-floating candidate, and brown dwarfs, which are very difficult to be detected by other techniques including radial velocity and transit. In 2019, the KMTNet alert will be available in real-time for all bulge fields. As before, we will continue to collaborate with Spitzer team to measure the microlens parallaxes, which are required for estimating physical parameters of the lens. Thus, the KMTNet alert will be helpful to select Spitzer targets again. Also we plan to do follow-up observations for high-magnification events to study the planet multiplicity function. The KMTNet alert will play an important role to do follow-up observations for high-magnification events. Also, we will search for free-floating planets with short timescale (< 3 days) to study the planet frequency in our Galaxy.

• Archives of Plastic Surgery
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• v.50 no.4
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• pp.361-369
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• 2023

The latissimus dorsi (LD) flap is a reliable option for breast reconstruction. This is particularly true in patients with contraindications to abdominally based autologous breast reconstruction. A systematic review of patient satisfaction and health related quality of life following LD breast reconstruction using the BREAST-Q survey was conducted. The scope of the review was to determine the degree of patient satisfaction following the procedure and to examine how patient satisfaction from the pedicled LD flap compares to other breast reconstructive procedures. A literature search on BREAST-Q in LD flap reconstruction was performed. Only articles written in English and in published peer-reviewed journals were included. Studies with less than 20 patients in their sample and those with a follow-up period of less than 1 year were excluded. Five articles representing 331 patients were reviewed, including one case-control study and four retrospective cohort studies. Level of evidence was either III (4) or IV (1). The average age was 53 with average body mass index of 25. Most reconstructions were delayed (67%) and unilateral (88%), and most patients required radiation (79%). The average length of follow-up was 36 months, and the response rate was 75%. Overall, patients who underwent LD flap reconstruction reported favorable outcomes in satisfaction domains and quality of life domains with few complications. A meta-analysis also demonstrated higher satisfaction in LD flap without implants compared with LD flap with implants. Patient-reported outcomes following LD breast reconstruction compare favorably with other techniques of breast reconstruction.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.53.4-54
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• 2021

Although the era of very large telescopes has come, small telescopes still have advantages for fast follow-up and long-term monitoring observation. Intensive monitoring survey of nearby galaxies (IMSNG) aims to understand the nature of the supernovae (SNe) by catching the early light curve from them with the network of small telescopes from 0.4-m to 1.0-m all around the world. To achieve the scientific goals with heterogeneous facilities, three factors are important. First, automatic processes as soon as data is uploaded will increase efficiency and shorten the time. Second, searching for transients is necessary to deal with newly emerged transients for fast follow-up observation. Finally, the Integrated process for different telescopes gives a homogeneous output, which will eventually make connections with the database easy. Here, we introduce the integrated pipeline, 'gppy' based on Python, for more than 10 facilities having various configurations and its performance. Processes consist of image pre-process, photometry, image align, image combine, photometry, and transient search. In the connected database, homogeneous output is summarized and analyzed additionally to filter transient candidates with light curves. This talk will suggest the future work to improve the performance and usability on the other projects, gravitational wave electromagnetic wave counterpart in Korea Observatory (GECKO), and small telescope network of Korea (SOMANGNET).