Objective: This entire study has two parts. Study I aimed to develop a psychological assessment scale and the study II aimed to investigate the effects of LFN (low frequency noise) on the psychological responses in humans, using the scale developed in the study I. Background: LFN is known to have a negative impact on the functioning of humans. The negative impact of LFN can be categorized into two major areas of functioning of humans, physiological and psychological areas of functioning. The physiological impact can cause abnormalities in threshold, balancing and/or vestibular system, cardiovascular system and, hormone changes. Psychological functioning includes cognition, communication, mental health, and annoyance. Method: 182 college students participated in the study I in development of a psychological assessment scale and 42 paid volunteers participated in the study II to measure psychological responses. The LFN stimuli consisted of 12 different pure tones and 12 different 1 octave-band white noises and each stimulus had 4 different frequencies and 3 different sounds pressure levels. Results: We developed the psychological assessment scale consisting of 17 items with 3 dimensions of psychological responses (i.e., perceived physical, perceived physiological, and emotional responses). The main findings of LFN on the responses were as follows: 1. Perceived psychological responses showed a linear relation with SPL (sound pressure level), that is the higher the SPL is, the higher the negative psychological responses were. 2. Psychological responses showed quadric relations with SPL in general. 3. More negative responses at 31.5Hz LFN than those of 63 and 125Hz were reported, which is deemed to be caused by perceived vibration by 31.5Hz. 'Perceived vibration' at 31.5Hz than those of other frequencies of LFN is deemed to have amplified the negative psychological response. Consequently there found different effects of low frequency noise with different frequencies and intensity (SPL) on multiple psychological responses. Conclusion: Three dimensions of psychological responses drawn in regard to this study differed from others in the frequencies and SLP of LFN. Negative psychological responses are deemed to be differently affected by the frequency, SPL of the LFN and 'feel vibration' induced by the LFN. Application: The psychological scale from our study can be applied in quantitative psychological measurement of LFN at home or industrial environment. In addition, it can also help design systems to block LFN to provide optimal conditions if used the study outcome, .i.e., the relations between physical and psychological responses of LFN.
The fabrication process of thin boron-doped nanocrystalline diamond (B-NCD) microelectrodes on fused silica single mode optical fiber cladding has been investigated. The B-NCD films were deposited on the fibers using Microwave Plasma Assisted Chemical Vapor Deposition (MW PA CVD) at glass substrate temperature of 475 ℃. We have obtained homogenous, continuous and polycrystalline surface morphology with high sp3 content in B-NCD films and mean grain size in the range of 100-250 nm. The films deposited on the glass reference samples exhibit high refractive index (n=2.05 at λ=550 nm) and low extinction coefficient. Furthermore, cyclic voltammograms (CV) were recorded to determine the electrochemical window and reaction reversibility at the B-NCD fiber-based electrode. CV measurements in aqueous media consisting of 5 mM K3[Fe(CN)6] in 0.5 M Na2SO4 demonstrated a width of the electrochemical window up to 1.03 V and relatively fast kinetics expressed by a redox peak splitting below 500 mV. Moreover, thanks to high-n B-NCD overlay, the coated fibers can be also used for enhancing the sensitivity of long-period gratings (LPGs) induced in the fiber. The LPG is capable of measuring variations in refractive index of the surrounding liquid by tracing the shift in resonance appearing in the transmitted spectrum. Possible combined CV and LPG-based measurements are discussed in this work.
Journal of Korean Society of Coastal and Ocean Engineers
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v.29
no.2
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pp.92-108
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2017
Present work shows a numerical method to analysis of interaction analysis between solitary wave and onshore bridge. Numerical simulation is carried out by TWOPM-3D (three-dimensional one-field model for immiscible two-phase flows), which is based on Navier-Stokes solver. To do this, the solitary wave is generated numerically in numerical wave channel, and numerical results and experimental results were compared and analyzed in order to verify the applicability of force acting on an onshore bridge. From this, we discussed precisely the characteristics of horizontal and vertical forces (uplift and downward forces) changes including water level and velocity changes due to the variation of solitary wave height, water depth, onshore bridge's location and type, and number of girder. Furthermore, It is revealed that the maximum horizontal and vertical forces acting on the girder bridge show different varying properties according to the number of girder, although each maximum force acting on the girder bridge is proportional to the increasement of incident solitary wave height, and the entrained air in the fluid flow affects the vertical force highly.
Purpose : There are two modalities, those are small bowel series(SBS) and abdominal pelvic computed tomography(CT), for diagnosis of small bowel disease. The aim of this study is to lend radiological technologists who are doing the two modalities assistance in the understanding characteristic of disease by comparing the two results. Meterials and method : 284 patients were examined the two SBS and abdominal pelvic CT together from 1999 to 2003. 250 ml $BaSO_4$ suspension 40 w/v% and 600ml carboxy methyl cellulose 0.5 w/v% were used for SBS. Abdominal Pelvic CT was examined in one hour before taking 450 ml $BaSO_4$ suspension 1.5 w/v%. The CT scan was done in 72 sec after 150 ml contrast media injection. the used protocol was helical mode 5:5 mm pitch 1.375:1, speed 27.50, exposure 120 kv, 240 mA, tube rotation time 0.5 sec. the statistic analysis was conducted with statistical program SPSS 10 version with frequency and crossing analysis. P-value less than 0.05 were considered significant. Results : In the results of SBS, normal findings were 131 patients(46.1%), inflammatory bowel disease(IBD) 64(22.9%), ischemia+ileocolitis+vasculitis 22(7.7%), Obstruction+stricture 21(7.7%) and Others 45(15.9%). In the results of abdominal pelvic CT, normal findings were 103 patients(36.3%), inflammatory bowel disease 65(22.9%), wall thickening+lymphadenopathy 42(14.8%), Fluid collection 17(6%), and Others 57case(20%). The same results of the two were 130patients(45.8%). 30patients(10.6%) of normal finding in SBS were diagnosed as wall thickening+lymphadenopathy and IBD in CT, and 15patients(5.3%) of normal finding in CT were diagnosed as ischemia+ileocolitis+vasculitis, mass and IBD in SBS(p<0.05). Transit time delay was diagnosed in 10patients(3.5%) on only SBS, wall thickening+lymphadenopathy was diagnosed in 20patients(7%) in only CT(p<0.05). Conclusion : We think that proper examination method will be selected in the small bowel disease, if we understand the characteristics of the disease and method.
Journal of the Korean Society of Marine Environment & Safety
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v.22
no.5
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pp.564-575
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2016
The present study provides numerical simulations to predict the added resistance and ship motion of the KVLCC2 in regular waves using the unsteady Reynolds-Averaged Navier-Stokes (URANS) and 3-D potential methods. This numerical analysis is focused on added resistance and vertical ship motions (heave and pitch) under a wide range of wave conditions at three ship speeds (design, operating and zero speeds). Firstly, the characteristics of the CFD and 3-D potential flow methods are presented to predict added resistance and ship motions in regular waves taking into account various wave conditions at design speed to provide a validation study as well as at operating and zero speeds. Secondly, analyses of added resistance and ship motion with unsteady wave patterns and time history results as simulated by CFD were performed at each ship speed. Systematic validation and verifications of the numerical computations in this study were made against available Experimental Fluid Dynamics (EFD) data including grid convergence tests to demonstrate that reliable numerical results were obtained for the prediction of added resistance and ship motion in waves. Relationships between added resistance, vertical motion and changes in ship speeds were also found.
Seo, Chang-Seob;Ha, Hyekyung;Lee, Ho Young;Lee, JunKyung;Jung, Dayoung;Lee, Jin-Ah;Shin, Hyeun Kyoo
Korean Journal of Pharmacognosy
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v.43
no.4
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pp.279-285
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2012
The Mume Fructus (MF) has been used for relieves cough, arrests arrest chronic diarrhea, treat fluid depletion, and treat ascariasis in Korea. In this study, a high-performance liquid chromatography (HPLC) method was established for simultaneous determination of six main components of MF. Additionally, we were investigated the anti-inflammatory and anti-allergic effects of MF extract on lipopolysaccharide (LPS)-treated RAW264.7 cells and tumor necrosis factor (TNF)-${\alpha}$/interferon (IFN)-${\gamma}$-treated HaCaT cells. The analytical column for separation was used a Gemini $C_{18}$ column maintained at $40^{\circ}C$. The mobile phase consisted of 1.0% (v/v) acetic acid in water (A) and 1.0% (v/v) acetic acid in acetonitrile (B). The flow rate was 1.0 mL/min and the detector was a photodiode array (PDA) set at 280 nm and 320 nm. We evaluated the inhibitory effect of MF extract on the production of inflammatory markers, nitric oxide (NO) and prostaglandin $E_2$ ($PGE_2$) in LPS-stimulated RAW264.7 cells and thymus- and activation-regulated chemokine (TARC/CCL17) in TNF-${\alpha}$/IFN-${\gamma}$-treated HaCaT cells, respectively. We confirmed the genes expression related with TARC, macrophage-derived chemokine (MDC/CCL22) and regulated on activation, normal T cell expressed and secreted (RANTES/CCL5) in HaCaT keratinocyte cells by MF extract. The contents of the five compounds in MF were 0.22-1.01 mg/g. Also, the MF extract show inhibition of about 78% and 75% on NO and $PGE_2$ production at the concentration 1000 mg/mL in RAW264.7 cells. MF extract suppressed the hTARC level and genes expression such as TARC, MDC, and RANTES on TNF-${\alpha}$/IFN-${\gamma}$-treated HaCaT cells.
Jin-kwan Choi;Won-kyung Yang;Su-won Lee;Seong-cheon Woo;Seung-hyung Kim;Yang-chun Park
The Journal of Internal Korean Medicine
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v.45
no.1
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pp.11-30
/
2024
Objectives: This study evaluated the effects of Ssanghwa-tang (SHT) on lung injury and muscle loss in a COPD mouse model. Methods: C57BL/6 mice were challenged with cigarette smoke extract and lipopolysaccharide, and then treated with two concentrations of SHT (250 and 500 mg/kg). After sacrifice, the bronchoalveolar lavage fluid (BALF) or lung tissue was analyzed by cytospin, ELISA, real-time PCR, flow cytometry analysis, and H&E and Masson's trichrome staining. The grip strength of COPD mice was measured using a grip strength meter. The running time of COPD mice was measured by a treadmill test. Muscle tissue of the quadriceps was stained with H&E and Masson's trichrome staining. Results: SHT significantly inhibited the increase in neutrophil numbers in BALF and significantly decreased immune cell activity in BALF and lung tissue. It also significantly inhibited the increase in TNF-α, IL-17, and MIP2 in BALF. Real-time PCR analysis revealed that the mRNA expression of TNF-α, IL-17, MIP2, and TRPV1 in lung tissue showed a significant decrease compared with the control group. Lung tissue damage was significantly reduced in the histological analysis. The grip strength and running time of the COPD mice showed a significant decrease compared with the control group. In histological staining, SHT was found to reduce the damage to muscle tissue. Conclusions: This study indicates that SHT can be used as a therapeutic agent for COPD patients by inhibiting lung injury and muscle loss.
Due to the limited areal space for installation, borehole heat exchangers (BHEs) at depths deeper than 300 m are considered for geothermal heating and cooling in the urban area. The deep vertical closed-loop BHEs are unconventional due to the depth and the range of the typical installation depth is between 100 and 200 m in Korea. The BHE in the study consists of 50A (outer diameter 50 mm, SDR 11) PE U-tube pipe in a 150 mm diameter borehole with the depth of 300 m. In order to compensate the buoyancy caused by the low density of PE pipe ($0.94{\sim}0.96g/cm^3$) in the borehole filled with ground water, 10 weight band sets (4.6 kg/set) were attached to the bottom of U-tube. A thermal response test (TRT) and fundamental basic surveys on the thermophysical characteristics of the ground were conducted. Ground temperature measures around $15^{\circ}C$ from the surface to 100 m, and the geothermal gradient represents $1.9^{\circ}C/100m$ below 100 m. The TRT was conducted for 48 hours with 17.5 kW heat injection, 28.65 l/min at a circulation fluid flow rate indicates an average temperature difference $8.9^{\circ}C$ between inlet and outlet circulation fluid. The estimated thermophysical parameters are 3.0 W/mk of ground thermal conductivity and 0.104 mk/W of borehole thermal resistance. In the stepwise evaluation of TRT, the ground thermal conductivity was calculated at the standard deviation of 0.16 after the initial 13 hours. The sensitivity analysis on the borehole thermal resistance was also conducted with respect to the PE pipe diameter and the thermal conductivity of backfill material. The borehole thermal resistivity slightly decreased with the increase of the two parameters.
The Kusandong Tuff, known as a representative key bed in the Cretaceous Gyeongsang Basin, is a crystal-rich tuff of pyroclastic flow and surge origin. It is 1-4 m thick and laterally extends for more than 200 km intercalated in the upper part of the Hayang Croup. Observations and analyses of the feldspar crystals in the tuff, using polarizing microscopes, EPMA, and BSE images, reveal that the plagioclase crystals in the tuff were completely albitized (>$97\%$ Ab) whereas those in the southernmost localities where the tuff is rich in fine ash matrix are unaltered or partly albitized. K-feldspars are partly albitized at all localities, irrespective of the matrix content of the tuff, Perthitic textures, chessboard twinning, albitization along micro-fractures and cleavages, and the relationship between matrix content and the degree of albitization suggest that feldspars in the Kusandong Tuff were albitized by Na-rich fluid after burial. Albitization is interpreted to start preferentially along micro-fractures and cleavages and be hampered in matrix-rich tuffs with a low permeability. Original composition of the plagioclases in the Kusandong Tuff is also interpreted to have ranged between oligoclase and andesine ($Ab_{62.5}-Ab_{83.3}$) before the albitization.
Journal of Fisheries and Marine Sciences Education
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v.5
no.1
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pp.31-44
/
1993
Through the early 1900's, the evolution of the surface condenser was closely tied to the development of steam engine and the turbine. As the chemical and petroleum industries evolved in the 1900's, the use of surface condensers in many different processes. Today, industry uses condensers in many shapes and sizes. The actual condensation process occurs on the outside surface of tubes. The nature of this surface geometry affects the condenser's heat transfer performance. The first condensers were built with plain tubes. As tube manufacturing techniques advanced, manufacturers started making tubes with integral fins. In the 1940's, fin densities were limited to about 600 to 700 fins per meter(fpm) because of manufacturing procedure. Today new manufacturing techniques allow production of tubes with fin densities ranging from 750 to 1600 fpm. The integral-fin tubes investigated in this paper are nominally 19 mm diameter. Eight tubes have been used with trapezodially shaped integral-fins having fin density from 748 to 1654 fpm and 10, 30 grooves. For comparison, tests are made using a plain tube having the same inside diameter and an outside diameter equal to that at the root of the fins for the finned tubes. Betty and Katz's theoretical modelis is used to predict the R-11 condensation coefficient on horizontal integral-fin tubes having 748, 1024 and 1299 fpm. Experiments are carried out using R-11 as working fluid. The refrigerant condensates at a saturation state of $30^{\circ}C$ on the outside tube surface cooled by coolant. The amount of noncondensable gases present in the test loop is reduced to a negligible value by repeated purging. For a given heat input to the boiler and given cooling water flow rate, all test data are taken at steady state. The observed heat transfer enhancement for the finned and grooved tubes significantly exceeded that to be expected on grounds of increased area. For the eight fin tubes and one plain tube tested, the best performance has been obtained with a tube having a fin density of 1299 fpm, and a fin bight of 1.2mm and 30 grooves.
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