• 대한물리치료과학회지
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• 제27권3호
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• pp.1-11
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• 2020

Background: The purpose of this study was to investigated the effects of threshold resistance inspiratory muscle training on respiratory function in chronic stroke patients. Design: Randomized Controlled Trial Methods: Eighteen patient with stroke were randomly assigned to the experimental group (n=9) and control group (n=9) all testing and training. The experimental group underwent threshold resistance inspiratory muscle training with resistance adjusted of maximal inspiratory pressure, 60 breathing a day and general physical therapy 30 minutes a day, 5 times a week for 4 weeks. The control group was taken general respiratory muscle training and general physical therapy for 4 weeks in the same way. Respiratory function, walking ability were evaluated before and after the intervention. Statistical significance of the results were evaluated by ANCOVA between control group and experimental group after intervention. Results: There was a significant increase in FVC and FEV1 in the experimental group in pulmonary function tests (p<0.05). There was a significant difference with the maximum inspiratory pressure and the maximum inspiratory flow rate between experimental and control group (p<0.05). There was no significant difference with the maximum inspiratory capacity between experimental and control group (p>0.05) but the maximum inspiratory capacity of experimental group some increased than that of control group. Conclusion: These finding gave some indications that the threshold resistance inspiratory training may benefit on pulmonary function in people with stroke, and it is feasible to be included in rehabilitation interventions with this population.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제11권7호
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• pp.205-216
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• 2022

딥러닝 분산 학습에 사용되는 많은 도구 중 하나는 컨테이너 오케스트레이션 도구인 쿠버네티스에서 실행되는 큐브플로우이다. 그리고 큐브플로우에서 기본적으로 제공하는 오퍼레이터를 사용하여 텐서플로우 학습 작업을 관리할 수 있다. 하지만 파라미터 서버 아키텍처 기반의 딥러닝 분산 학습 작업을 고려할 때 기존의 오퍼레이터가 사용하는 스케줄링 정책은 분산학습 작업의 태스크 친화도를 고려하지 않으며 자원을 동적으로 할당하거나 해제하는 기능을 제공하지 않는다. 이는 작업의 완료 시간이 오래 걸리거나 낮은 자원 활용률로 이어질 수 있다. 따라서 본 논문에서는 작업의 완료 시간을 단축시키고 자원 활용률을 높이기 위해 딥러닝 분산 학습 작업을 효율적으로 스케줄링하는 새로운 오퍼레이터를 제안한다. 기존 오퍼레이터를 수정하여 새로운 오퍼레이터를 구현하고 성능 평가를 위한 실험을 수행한 결과, 제안한 스케줄링 정책은 평균 작업 완료 시간 감소율을 최대 84%, 평균 CPU 활용 증가율을 최대 92%까지 향상시킬 수 있음을 보여준다.

• 문화기술의 융합
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• 제7권4호
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• pp.203-210
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• 2021

본 연구는 노력성 호흡 운동 중심의 촛불끄기 호흡훈련이 성인의 몸통 근력 강화를 의미하는 호흡 능력 향상에 어떤 유의한 효과가 있는지를 알아보기 위하여 실시하였다. 4주간의 촛불끄기 훈련을 통해 실험 전-후의 노력성폐활량(FVC)은 통계학적으로 유의하게 증가하였다(p<.05). 4주간의 촛불 끄기 훈련을 통해 실험 전-후의 1초간 노력성 날숨량(FEV1)의 변화는 통계학적으로 유의한 차이를 보이지 않았다(p>.05). 4주간의 촛불 끄기 훈련을 통해 실험 전-후의 최대날숨유속(PEF)은 유의하게 증가하였다(p<.05). 본 연구는 건강한 성인을 대상으로 노력성 호흡 운동 중심의 촛불끄기 호흡운동을 실시하여 성인의 몸통 근력 강화를 의미하는 노력성 폐활량(FVC), 1초간 노력성 날숨량(FEV1), 최대날숨유속(PEF) 등의 노력성 호흡훈련과 허파기능의 관계에 대해 조사하여 유의한 결과를 얻었다. 앞으로 물리치료가 꼭 필요한 중증 호흡기계 질환자를 대상으로 하는 연구가 진행되어야 할 것으로 사료된다.

• 한국정보통신학회논문지
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• 제26권12호
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• pp.1832-1837
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• 2022

대학교에서 컴퓨터 관련 학과를 졸업하거나 관련된 직업을 갖지 않은 자를 말하는 비전공자의 SW교육에서 교양교육을 접하는 학습자는 처음 접하는 SW 개발환경과 이해, 전공과의 관련성, 융합 사고능력 등의 어려움을 겪게 된다. 교양교육에서 비전공 학습자의 어려움을 보완하고자 비교적 쉽게 접근할 수 있는 소프트웨어를 활용하여 SW교육 초보자에게 적용할 수 있는 시연 중심모델을 활용하였다. 실생활에서 사용되는 애플리케이션과 문제해결의 논리적 흐름을 파악할 수 있도록 교수자의 시연과 학습자의 모방을 통한 반복적인 구현과 학습자의 학습 만족도와 성취도를 높이기 위한 학습지표를 결합한 융합 SW 교수법을 제안하였다. 본 논문에서 제안한 교수학습법을 적용한 실험에서 SW 교육의 학습 효과, 학업 성취도, 학습 만족도, 교수학습법 측면을 평가할 때 의미 있는 결과를 보였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.319-319
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• 2023

Flows of water in the environment (e.g. in a river or estuary) generally occur in complex conditions. This complexity can hinder a general understanding of flows and their related sedimentary processes, such as erosion and deposition. To gain insight in simplified, controlled conditions, hydraulic flumes are a popular type of laboratory research equipment. Linear flumes use pumps to recirculation water. This isn't appropriate for the investigation of cohesive sediments as pumps can break fragile cohesive sediment flocs. To overcome this limitation, the rotating annular flume (RAF) was developed. While not having pumps, a side-effect is that unwanted secondary circulations can occur. To counteract this, the top and bottom lid rotate in opposite directions. Furthermore, a larger flume is considered better as it has less curvature and secondary circulation. While only a few RAFs exist, they are important for theoretical research which often underlies numerical models. Many of the first-generation of RAFs have come into disrepair. As new measurement techniques and models become available, there is still a need to research cohesive sediment erosion and deposition in facilities such as a RAF. New RAFs also can have the advantage of being automatic instead of manually operated, thus improving data quality. To further advance our understanding of cohesive sediment erosion and deposition processes, a large, automatic RAF (1.72 m radius, 0.495 m channel depth, 0.275 m channel width) has been constructed at the Hydraulic Laboratory at Chungnam National University (CNU), Korea. The RAF has the ability to simulate both unidirectional (river) and bidirectional (tide) flows with supporting instrumentation for measuring turbulence, bed shear stress, suspended sediment concentraiton, floc size, bed level, and bed density. Here we present the current status and future prospect of the CNU RAF. In the future, calibration of the rotation rate with bed shear stress and experiments with unidirectional and bidirectional flow using cohesive kaolinite are expected. Preliminary results indicate that the CNU RAF is a valuable tool for fundamental cohesive sediment transport research.

• Journal of Microbiology and Biotechnology
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• 제33권10호
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• pp.1384-1389
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• 2023

This work aimed to evaluate the feasibility of biohydrogen production from Barley Straw and Miscanthus. The primary obstacle in plant biomass decomposition is the recalcitrance of the biomass itself. Plant cell walls consist of cellulose, hemicellulose, and lignin, which make the plant robust to decomposition. However, the hyperthermophilic bacterium, Caldicellulosiruptor bescii, can efficiently utilize lignocellulosic feedstocks (Barley Straw and Miscanthus) for energy production, and C. bescii can now be metabolically engineered or isolated to produce more hydrogen and other biochemicals. In the present study, two strains, C. bescii JWCB001 (wild-type) and JWCB018 (ΔpyrFA Δldh ΔcbeI), were tested for their ability to increase hydrogen production from Barley Straw and Miscanthus. The JWCB018 resulted in a redirection of carbon and electron (carried by NADH) flow from lactate production to acetate and hydrogen production. JWCB018 produced ~54% and 63% more acetate and hydrogen from Barley Straw, respectively than its wild-type counterpart, JWCB001. Also, 25% more hydrogen from Miscanthus was obtained by the JWCB018 strain with 33% more acetate relative to JWCB001. It was supported that the engineered C. bescii, such as the JWCB018, can be a parental strain to get more hydrogen and other biochemicals from various biomass.

• 한국자원식물학회지
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• 제36권6호
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• pp.588-596
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• 2023

Long-term culture of cell lines is an important issue in in vitro culture and in plant science. In this study, the regeneration ability and ex vitro acclimatization of regenerants were evaluated. The ploidy level of regenerants derived from long-term cultured cell lines was measured in Imperata cylindrica 'Rubra', Poaceae. Adventitious buds (shoots) were successfully induced from five-year-cultured calli on MS medium containing 0.1 mg/L BA or 2.0 mg/L TDZ, combined with 0.01 mg/L auxins (IAA, IBA, NAA and 2,4-D), respectively. Adventitious roots were also induced on MS medium containing 0.01 mg/L auxins (IBA, NAA and 2,4-D), respectively. Interestingly, regenerants with both red and green leaf were successfully obtained when regenerants were cultured on MS medium with 9% sucrose. Regenerants derived from long-term cultured calli were transferred to pots using an optimal acclimatization process and successfully adapted to both pot and soil conditions. Moreover, the ploidy level was measured using calli and regenerants that had been kept on MS medium containing various kinds of plant growth regulators (PGRs).

• Composites Research
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• 제36권5호
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• pp.310-314
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• 2023

VaRTM(Vacuum assisted resin transfer molding)과 VAP(Vacuum assisted process) 공정은 RTM(Resin transfer modling) 공정의 한 종류로서, 대형구조물을 저가에 제작할 수 있는 대표적인 탈 오토클레이브(OOA, Out of Autoclave) 공정이다. 본 논문에서는 VaRTM과 VAP 공정을 상호 비교하기 위하여 수지 충진시험을 진행하였으며, 충진과정과 치수 안정성 등을 상호 비교하였다. 또한, 충진과정을 모사할 수 있는 해석기법을 개발하였으며, 유전센서를 사용하여 수지의 유동선단을 검출하여 이를 해석결과와 상호 비교하였다. 수지 충진시험 결과, 복합재 평판의 총 충진시간은 VAP공정은 48분, VaRTM 공정은 145분으로 측정되어, VAP 공정에 의한 충진시간이 VaRTM 대비 약 67% 단축되었으며, VAP공정이 VaRTM 공정에 비해 복합재 평판의 두께조절능력과 균일도가 우수함을 확인하였다.

• Journal of Ginseng Research
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• 제47권6호
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• pp.706-713
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• 2023

Background and objective: The ability to inhibit aggregation has been demonstrated with synthetically derived ginsenoside compounds G-Rp (1, 3, and 4) and ginsenosides naturally found in Panax ginseng 20(S)-Rg3, Rg6, F4, and Ro. Among these compounds, Rk3 (G-Rk3) from Panax ginseng needs to be further explored in order to reveal the mechanisms of action during inhibition. Methodology: Our study focused to investigate the action of G-Rk3 on agonist-stimulated human platelet aggregation, inhibition of platelet signaling molecules such as fibrinogen binding with integrin α_IIbβ₃ using flow cytometry, intracellular calcium mobilization, dense granule secretion, and thromboxane B₂ secretion. In addition, we checked the regulation of phosphorylation on PI3K/MAPK pathway, and thrombin-induced clot retraction was also observed in platelets rich plasma. Key Results: G-Rk3 significantly increased amounts of cyclic adenosine monophosphate (cAMP) and led to significant phosphorylation of cAMP-dependent kinase substrates vasodilator-stimulated phosphoprotein (VASP) and inositol 1,4,5-trisphosphate receptor (IP₃R). In the presence of G-Rk3, dense tubular system Ca²⁺ was inhibited, and platelet activity was lowered by inactivating the integrin αIIb/β₃ and reducing the binding of fibrinogen. Furthermore, the effect of G-Rk3 extended to the inhibition of MAPK and PI3K/Akt phosphorylation resulting in the reduced secretion of intracellular granules and reduced production of TXA₂. Lastly, G-Rk3 inhibited platelet aggregation and thrombus formation via fibrin clot. Conclusions and implications: These results suggest that when dealing with cardiovascular diseases brought upon by faulty aggregation among platelets or through the formation of a thrombus, the G-Rk3 compound can play a role as an effective prophylactic or therapeutic agent.

• 한국정보전자통신기술학회논문지
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• 제17권1호
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• pp.38-46
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• 2024

일반적으로 EEG 신호 분석은 의료 진단 및 재활 공학에 적용하여 뇌-컴퓨터 인터페이스 연구에 널리 사용되는 뇌 자극을 기록하는 객관적인 모드를 제공할 수 있는 능력 때문에 여러 연구의 주제가 되어 왔습니다. 본 연구에서는 뇌전도 측정하기 위한 뇌파 수신 하드웨어 개발 및 처리 시스템 구현을 통해 서버와 데이터 처리로 분류하여 개발을 진행하였다. 뇌전도를 이용한 뇌-컴퓨터 인터페이스 구현의 중간단계 연구로 진행되었으며, 측정된 뇌전도 데이터에 따라 사용자의 팔의 움직임을 예측하는 형태로 구현되었다. 네 개의 전극으로부터의 입력을 아날로그-디지털 변환기를 통해 뇌전도 측정을 수행하였다. 이를 통신 과정을 거쳐 서버에 전송한 뒤, 서버에서 합성곱 신경망 모델로 뇌전도 입력을 분류하여 그 결과를 사용자 단말로 표시하는 시스템의 흐름을 설계하고 구현하였다.