• 한국방사선학회논문지
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• 제17권5호
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• pp.725-733
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• 2023

본 연구의 목적은 가상 그리드 소프트웨어(VGS)의 유효성을 평가하기 방법으로 이동형 그리드를 사용하지 않은 상태에서 VGS를 사용할 때와 사용하지 않을 때(Without-VGS)로 구분하여 에너지와 피사체 두께에 변화를 주고 흉부 팬텀과 대퇴부 팬텀을 이용하여 영상을 획득하고, SNR과 CNR을 분석하여 VGS의 유효성을 알아보고자 하였다. 흉부 팬텀과 대퇴부 팬텀에서 관전류는 2.5 mAs로 고정하고, 관전압을 60 ~ 100 kVp에서 10kVp 씩 변화하여 X선 조사한 후 SNR과 CNR을 측정한 결과 흉부 팬텀에서 SNR은 Without-VGS 보다 VGS에서 약 1.09 ~ 8.86% 높게 나타났고, CNR은 Without-VGS 보다 VGS에서 4.18 ~ 14.56% 높게 나타났다. 그리고 대퇴부 팬텀에서는 SNR이 Without-VGS 보다 VGS에서 약 9.78 ~ 18.05% 높게 나타났고, CNR은 Without-VGS 보다 VGS에서 21.07 ~ 44.44% 높게 나타났다. 흉부 팬텀과 대퇴부 팬텀에서 관전압을 70 kVp로 고정하고, 관전류량은 2.5 ~ 16 mAs에서 각각 변화하여 X선 조사한 후 SNR과 CNR을 측정한 결과 흉부 팬텀에서 SNR은 Without-VGS 보다 VGS에서 약 1.49 ~ 11.11% 높게 나타났고, CNR은 Without-VGS 보다 VGS에서 4.76 ~ 13.40% 높게 나타났다. 그리고 대퇴부 팬텀에서는 SNR은 Without-VGS 보다 VGS에서 약 2.22 ~ 17.38% 높게 나타났고, CNR은 Without-VGS 보다 VGS에서 13.85 ~ 40.46% 높게 나타났다. 결론적으로 Without-VGS 보다 VGS를 사용할 때 SNR과 CNR이 높게 나타났다. 그러므로 이동형 X선 촬영장치로 검사를 해야 하는 경우 이동형 그리드를 사용하기 어려운 환경에서 VGS를 사용함으로써 좋은 영상의 화질을 얻을 수 있어 검사에 유용하게 사용될 것으로 판단되고, 이동형 X선 장치의 활용성을 증대시킬 수 있을 것으로 판단된다.

• 전기전자학회논문지
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• 제28권2호
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• pp.187-198
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• 2024

Estimating the phase boundary in two-phase flow is crucial for designing and optimizing industrial processes. Electrical impedance tomography (EIT) is a promising technique for imaging phase distribution in such flows. This paper proposes using a cuckoo search (CS) optimization algorithm to estimate the phase boundary with EIT. The boundary is parameterized using the Fourier series, and the coefficients are determined by the CS algorithm. The CS algorithm iteratively seeks the phase boundary configuration by minimizing a cost function. Computer simulations and phantom experiments demonstrate the effectiveness of this method in estimating phase boundaries in two-phase flow.

• 한국자기공명학회논문지
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• 제7권1호
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• pp.62-67
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• 2003

MRI of laser-polarized $^{129}$ Xe under continuous flow conditions has recently been used for imaging of porous materials, however, any attempts at using a continuously circulating flow of laser-polarized $^3$He have not been made until now, presumably due to its extremely long spin exchange time (5-10 hrs). Since the inherent NMR sensitivity of $^3$He is 80 times greater than that of $^{129}$ Xe when considering the natural abundance, $^3$He can be expected to be a better nucleus for imaging than $^{129}$ Xe even under continuous flow conditions. In this report, the first MRI with continuously flowing laser-polarized $^3$He is shown for a phantom of Teflon tubing, demonstrating the feasibility of $^3$He imaging under continuous flow.

• 한국수소및신에너지학회논문집
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• 제16권3호
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• pp.253-261
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• 2005

석유 연료 고갈 해결 및 온실 효과 가스 배풀 저감을 위한 방안으로 제시되는 수소는 다양한 에너지 저장체로 사용되어 질 수 있으나 안전성에 대한 연구가 요구되어진다. 따라서, 일반적인 저장 형태인 고압 저장 탱크에서 누출이 되었을 경우 분사되는 수소의 거동에 대한 연구가 이루어져야하며 이를 바탕으로 한 보완책이 제시되어야 한다. 이번 연구에서는 누설 시 확산되는 수소의 밀도를 실제 거동과 유사한 3차원 컴퓨터 영상장으로 합성한 후 ART(algebraic reconstruction technique) 및 MART(multiplicative ART)를 기반으로 한 3차원 디지털 스페클 토모그래피 기법을 개발하여 재건하고 분석하였다.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2005년도 추계 학술대회논문집
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• pp.255-259
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• 2005

An analysis is made of flow and rocket motion during a supersonic separation stage of air-launching rocket from the mother plane. Three-dimensional Euler and Navier-Stokes equations are numerically solved to analyze the steady/unsteady flow field around the rocket which is being separated from two cases of mother plane configuration: one is an idealized ogive-cylinder body and the other is a real F-4E Phantom. The simulation results clearly demonstrate the effect of shock-expansion wave interaction between the rocket and the mother plane. As a result, a design-guideline of supersonic air-launching rocket for the safe separation is proposed.

• 비파괴검사학회지
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• 제25권6호
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• pp.431-438
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• 2005

Bubble behaviors in a circular tube have been analyzed numerically and experimentally by a three-dimensional tomography method, Initially, a multiplicative algebraic reconstruction technique (MART) which showed better results for previous studies of numerical simulations has been performed to confirm the accuracy of the three-dimensional reconstruction for the two-phase flow using a computer-synthesized phantom, Then, bubble behaviors have been investigated experimentally by the three-dimensional MART method using real projected data captured simultaneously by a laser and three CCD cameras for three angles of view, Also, the transient reconstructions have been attempted to analyze the real-time oxygen-bubble movements in water by the interval of 1/30 second.

• 핵의학기술
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• 제22권1호
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• pp.46-50
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• 2018

검출기 외부에 강한 선원은 collimator와 상호 작용으로 산란선이 만들어지게 되는데, 그 산란선이 영상에 얼마나 영향을 주는지 평가하고자 한다. SKY LITE를 사용하여, phantom study의 경우, $^{99m}Tc$ 1.11 GBq를 점선원으로 만들어 검출기 주변을 $10^{\circ}$ 간격으로 돌아가면서 측정하여 각 각도에서의 산란선의 정도를 계수율과 스펙트럼으로 분석을 하였다. Patient study의 경우, 3-phase bone scan을 하는 환자를 대상으로, blood flow와 blood pool 영상을 획득하면서 산란선의 양과 스펙트럼을 분석하였다. 추가로 blood pool 검사 시, 환자의 손위에 납가운을 올려놓고 영상을 획득하였고, 환자의 몸에 납가운을 입히고 영상을 획득하여 각 영상에서의 산란선과 스펙트럼을 비교, 평가하였다. 그 결과, phantom study의 경우, 후방에서는 산란선의 없었지만, 측면부터 전방 $50^{\circ}$ 까지는 산란선이 많이 검출 되었다. patient study의 경우 blood flow 영상과 blood pool 영상에서 환자 몸에서 나온 감마선으로 인해 생긴 산란선이 입사됨을 알 수 있었다. 그리고 납가운은 손 위를 차폐하는것 보다, 환자 몸을 차폐 하는 것이 산란선이 많이 줄었다. 그러므로 외부에 강한 선원이 존재하고, hand blood flow, blood pool 검사처럼 계수 자체가 낮을 검사를 할 경우, 몸에서 나오는 선원 자체를 차폐하는 것이 산란선을 줄이는데 보다 효과가 있으며, 영상에서도 배후 방사선을 줄이는데 효과가 있음을 알 수 있었다.

• 한국가시화정보학회지
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• 제21권2호
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• pp.14-23
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• 2023

The pressure difference across stenotic blood vessels is a commonly used clinical metric for diagnosing many cardiovascular diseases. At present, most clinical pressure measurements rely solely on invasive catheterization. In this study, we propose a novel method for non-invasive pressure estimation using the incompressible Navier-Stokes equations and a 3D multi-path integration approach. We verify spatio-temporal convergence on an in-silico dataset of a cylindrical straight pipe phantom with steady and pulsatile flow fields. We then evaluate the proposed method on an in vitro dataset of reconstructed control, pre-operative, and post-operative carotid artery cases acquired from 4D flow MRI. The performance of our method is compared to existing approaches based on the pressure Poisson equation and work-energy relative pressure. The results demonstrate the proposed method's high accuracy, robustness to spatio-temporal subsampling, and reduced sensitivity to noise, highlighting its great potential for non-invasive pressure estimation.

• Korean Journal of Radiology
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• 제24권7호
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• pp.647-659
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• 2023

Objective: The study was conducted to investigate the effect of correct occlusion of the left atrial appendage (LAA) on intracardiac blood flow and thrombus formation in patients with atrial fibrillation (AF) using four-dimensional (4D) flow magnetic resonance imaging (MRI) and three-dimensional (3D)-printed phantoms. Materials and Methods: Three life-sized 3D-printed left atrium (LA) phantoms, including a pre-occlusion (i.e., before the occlusion procedure) model and correctly and incorrectly occluded post-procedural models, were constructed based on cardiac computed tomography images from an 86-year-old male with long-standing persistent AF. A custom-made closed-loop flow circuit was set up, and pulsatile simulated pulmonary venous flow was delivered by a pump. 4D flow MRI was performed using a 3T scanner, and the images were analyzed using MATLAB-based software (R2020b; Mathworks). Flow metrics associated with blood stasis and thrombogenicity, such as the volume of stasis defined by the velocity threshold ($\left|\vec{V}\right|$ < 3 cm/s), surface-and-time-averaged wall shear stress (WSS), and endothelial cell activation potential (ECAP), were analyzed and compared among the three LA phantom models. Results: Different spatial distributions, orientations, and magnitudes of LA flow were directly visualized within the three LA phantoms using 4D flow MRI. The time-averaged volume and its ratio to the corresponding entire volume of LA flow stasis were consistently reduced in the correctly occluded model (70.82 mL and 39.0%, respectively), followed by the incorrectly occluded (73.17 mL and 39.0%, respectively) and pre-occlusion (79.11 mL and 39.7%, respectively) models. The surfaceand-time-averaged WSS and ECAP were also lowest in the correctly occluded model (0.048 Pa and 4.004 Pa^-1, respectively), followed by the incorrectly occluded (0.059 Pa and 4.792 Pa^-1, respectively) and pre-occlusion (0.072 Pa and 5.861 Pa^-1, respectively) models. Conclusion: These findings suggest that a correctly occluded LAA leads to the greatest reduction in LA flow stasis and thrombogenicity, presenting a tentative procedural goal to maximize clinical benefits in patients with AF.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.341-344
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• 2002

Neurodegenerative disorders, like Alzheimer's disease, are often accompanied by reduced brain perfusion (cerebral blood flow). Using the intrinsic magnetic properties of water, arterial spin labeling magnetic resonance imaging (ASLMRI) can map brain perfusion without injection of radioactive tracers or contrast agents. However, accuracy in measuring perfusion with ASL-MRI can be limited because of contributions to the signal from stationary spins and because of signal modulations due to transient magnetic field effects. The goal was to optimize ASL-MRI for perfusion measurements in the aging human brain, including brains with Alzheimer's disease. A new ASL-MRI sequence was designed and evaluated on phantom and humans. Image texture analysis was performed to test quantitatively improvements. Compared to other ASL-MRI methods, the newly designed sequence provided improved signal to noise ratio improved signal uniformity across slices, and thus, increased measurement reliability. This new ASL-MRI sequence should therefore provide improved measurements of regional changes of brain perfusion in normal aging and neurodegenerative disorders.