• Journal of Convergence for Information Technology
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• v.12 no.4
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• pp.158-165
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• 2022

Journal of Convergence for Information Technology. This study explores how native speakers (NSs) and non-native speakers (NNSs) of English negotiate meanings during conversational interactions to achieve successful communication. This study involved 40 participants: 20 native English speakers and 20 Korean university students. The participants were divided into 20 pairs, with each pair consisting of one NS and one NNS. Tasks for conversation were given and the execution recorded in order to collect data. 37 recorded conversations were transcribed and used for analysis, including statistical analyses. Results showed that both NSs and NNSs mutually put in effort for successful communication. While NSs mostly played the role of leading the natural flow of the conversation, encouraging their non-native interlocutors to speak, NNSs used various strategies to compensate for their lack of linguistic competence in the target language. NNSs employed a wide range of communicative strategies to keep the conversation going. The results of this study contribute to a better understanding of interactions between NSs and NNSs and yield pedagogical implications.

• Tuberculosis and Respiratory Diseases
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• v.85 no.2
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• pp.147-154
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• 2022

Background: The expression of calcium signaling pathway molecules is altered in various carcinomas, which are related to the proliferation and altered characteristics of cancer cells. However, changes in calcium signaling in anti-cancer drug-resistant cells (bearing a T790M mutation in epidermal growth factor receptor [EGFR]) remain unclear. Methods: Afatinib-mediated changes in the level of store-operated Ca²⁺ entry (SOCE)-related proteins and intracellular Ca²⁺ level in non-small cell lung cancer cells with T790M mutation in the EGFR gene were analyzed using western blot and ratiometric assays, respectively. Afatinib-mediated autophagic flux was evaluated by measuring the cleavage of LC3B-II. Flow cytometry and cell proliferation assays were conducted to assess cell apoptosis and proliferation. Results: The levels of SOCE-mediating proteins (ORAI calcium release-activated calcium modulator 1 [ORAI1], stromal interaction molecule 1 [STIM1], and sarco/endoplasmic reticulum Ca²⁺ ATPase [SERCA2]) decreased after afatinib treatment in non-small cell lung cancer cells, whereas the levels of SOCE-related proteins did not change in gefitinib-resistant non-small cell lung cancer cells (PC-9/GR; bearing a T790M mutation in EGFR). Notably, the expression level of SOCE-related proteins in PC-9/GR cells was reduced also responding to afatinib in the absence of extracellular Ca²⁺. Moreover, extracellular Ca²⁺ influx through the SOCE was significantly reduced in PC-9 cells pre-treated with afatinib than in the control group. Additionally, afatinib was found to decrease the level of SOCE-related proteins through autophagic degradation, and the proliferation of PC-9GR cells was significantly inhibited by a lack of extracellular Ca²⁺. Conclusion: Extracellular Ca²⁺ plays important role in afatinib-mediated autophagic degradation of SOCE-related proteins in cells with T790M mutation in the EGFR gene and extracellular Ca²⁺ is essential for determining anti-cancer drug efficacy.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.589-600
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• 2022

Investigations on the molten-pool sloshing behavior are of essential value for improving nuclear safety evaluation of Core Disruptive Accidents (CDA) that would be possibly encountered for Sodium-cooled Fast Reactors (SFR). This paper is aimed at synthesizing the knowledge from our recent studies on molten-pool sloshing behavior with solid particles conducted at the Sun Yat-sen University. To better visualize and clarify the mechanism and characteristics of sloshing induced by local Fuel-Coolant Interaction (FCI), experiments were performed with various parameters by injecting nitrogen gas into a 2-dimensional liquid pool with accumulated solid particles. It was confirmed that under different particle-bed conditions, three representative flow regimes (i.e. the bubble-impulsion dominant, transitional and bed-inertia dominant regimes) are identifiable. Aimed at predicting the regime transitions during sloshing process, a predictive empirical model along with a regime map was proposed on the basis of experiments using single-sized spherical solid particles, and then was extended for covering more complex particle conditions (e.g. non-spherical, mixed-sized and mixed-density spherical particle conditions). To obtain more comprehensive understandings and verify the applicability and reliability of the predictive model under more realistic conditions (e.g. large-scale 3-dimensional condition), further experimental and modeling studies are also being prepared under other more complicated actual conditions.

• Wind and Structures
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• v.34 no.1
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• pp.81-90
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• 2022

To better understand the vortex-induced vibration (VIV) characteristics of a 5:1 rectangular cylinder, the distribution of aerodynamic force and the non-dimensional power spectral density (PSD) of fluctuating pressure on the side surface were studied in different VIV development stages, and their differences in the stationary state and vibration stages were analyzed. The spanwise and streamwise correlations of surface pressures were studied, and the flow field structure partitions on the side surface were defined based on the streamwise correlation analysis. The results show that the variation tendencies of mean and root mean square (RMS) pressure coefficients are similar in different VIV development stages. The RMS values during amplitude growth are larger than those at peak amplitude, and the smallest RMS values are observed in the stationary state. The spanwise correlation coefficients of aerodynamic lifts increase with increase of the peak amplitude. However, for the lock-in region, the maximum spanwise correlation coefficient for aerodynamic lifts occurs in the VIV rising stage rather than in the peak amplitude stage, probably due to the interaction of vortex shedding force (VSF) and self-excited force (SEF). The streamwise correlation results show that the demarcation point positions between the recirculation region and the main vortex region remain almost constant in different VIV development stages, and the reattachment points gradually move to the tailing edge with increasing amplitude. This study provides a reference to estimate the demarcation point and reattachment point positions through streamwise correlation and phase angle analysis from wind tunnel tests.

• Ocean and Polar Research
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• v.45 no.3
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• pp.155-172
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• 2023

The collapse of ice shelves is a process that can severely increase the rise of global sea-levels through the reduction of the buttressing effect of ice shelves and the consequent acceleration of the ice flow of ice sheets. In recent years, the West Antarctic ice shelves in the Amundsen Sea, whose buttressing effect is essential for a great part of the West Antarctic ice sheet, have been experiencing the most rapid melting and thinning in the world. The melting of the West Antarctic ice shelves is caused primarily by heat transported by Circumpolar Deep Water (CDW). For this reason, it is important to investigate ice-ocean interactions that could influence the melting of ice shelves and evaluate the stability of West Antarctic ice shelves. A lot of researchers have been actively investigating the West Antarctic ice shelves in the Amundsen Sea. High-impact journals have recognized the importance of and published studies on ice-ocean interactions occurring near and under the ice shelves as well as the connections among ice shelves. However, in situ observations are limited due to extreme weather and sea-ice conditions near the ice shelves; therefore, many scientific questions remain unanswered. This study introduces the characteristics of the Amundsen Sea and investigate the past and latest research issues in this region. This study also gives suggestions regarding important scientific questions and directions for future research that should help early-career scientists take the lead in future research on the melting dynamics of the West Antarctic ice shelves in the Amundsen Sea.

• Structural Engineering and Mechanics
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• v.81 no.1
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• pp.81-91
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• 2022

The effects of interaction between concrete-gypsum interface and edge crack on the failure behavior of the specimens in senicircular bend (SCB) test were studied in the laboratory and also simulated numerically using the discrete element method. Some quarter circular specimens of gypsum and concrete with 5 cm radii and hieghts were separately prepared. Then the semicircular testing specimens were made by attaching one gypsum and one concrete sample to one another using a special glue and one edge crack is produced (in the interface) by do not using the glue in that part of the interface. The tensile strengths of concrete and gypsum samples were separately measured as 2.2 MPa and 1.3 MPa, respectively. during all testing performances a constant loading rate of 0.005 mm/s were stablished. The proposed testing method showed that the mechanism of failure and fracture in the brittle materials were mostly governed by the dimensions and number of discontinuities. The fracture toughnesses of the SCB samples were related to the fracture patterns during the failure processes of these specimens. The tensile behaviour of edge notch was related to the number of induced tensile cracks which were increased by decreasing the joint length. The fracture toughness of samples was constant by increasing the joint length. The failure process and fracture pattern in the notched semi-circular bending specimens were similar for both methods used in this study (i.e., the laboratory tests and the simulation procedure using the particle flow code (PFC2D)).

• Design Convergence Study
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• v.16 no.3
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• pp.69-84
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• 2017

Service blueprint is used to show the interaction between each service element at a glance and to understand the flow of the whole service centering on the customer at the stage of proposing a new service system. It was proposed in the 1980s before online business was developed. However, current services are changing in a way that provides various forms and channels, and the service blueprint seems to be not enough. To reflect this problem consciousness, we selected PSS among diversified service business models and propose a service blueprint type optimized for each business. After collecting 137 PSS cases to be used in the research, we made a business matrix and classified the cases and selected two representative cases to conduct two experiments. As a result, six types of service blueprint corresponding to the matrix could be derived: online service type, online remote support type, self rental type, online order type, traditional type, and offline support type. The validity of the proposed types of service blueprint was verified to confirm the suitability of those types.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.4B
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• pp.429-439
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• 2008

The purpose of this study is to examine the characteristics of run-up height over sandy beach due to the shape of submerged breakwater. For the discussion on it in detail, 3-Dimensional numerical model with Large Eddy Simulation, which is able to simulate directly interaction of Wave Structure Sandy beach (hereafter, LES-WASS-3D; Hur and Lee, 2007) has been used to simulate run-up height over sandy beach as well as wave field around submerged breakwaters. Using the results obtained from numerical simulation, the effects of the shape of submerged breakwaters (crown height, crown width, crown length and submerged breakwater's slope gradient) on run-up height over sandy beach have been discussed related to the wave height distribution and characteristics of up-layer flow around ones.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.5B
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• pp.591-594
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• 2008

Present study aims at the development of a reasonable boundary condition for a structure over inclined seabed in case of the numerical model with quadrilateral mesh system. The technique for the inclined impermeable/permeable boundary in the quadrilateral mesh is newly proposed. The new technique and LES-WASS-3D model (Hur and Lee, 2007) have been used for the investigation of the dynamics of fluid field, and validated through the comparison with a typical stair-type boundary condition. 3-Dimensional numerical model with Large Eddy Simulation is called LES-WASS-3D, and is able to simulate directly interaction of WAve Structure Sea bed/Sandy beach.

• The Journal of the Convergence on Culture Technology
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• v.9 no.4
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• pp.253-258
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• 2023

In comics, panels serve a variety of dramatic purposes, including controlling the flow of the story through the size, placement, and order of panels; directing the eye to where characters or specific actions take place; expressing the passage or sequence of time; and using backgrounds, lighting, and color to emphasize emotion and convey mood. When applied to VR animation, these comic panels can give users a more immersive experience of the cartoon world in the VR space. In the VR animation "Mescaformhill: Missing Five," produced in 2022, the comic panels directing is very important to guide the viewer's attention, and in the VR space, the camera angle can be freely changed to realize various visual effects, and the physical interaction brings the comic panels directing to life. This can open up new ways of storytelling in VR animation and contribute to its successful expansion into new mediums.