• The Journal of the Acoustical Society of Korea
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• v.39 no.5
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• pp.414-423
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• 2020

In this paper, we propose a Dilated Convolution Gate Linear Unit (DCGLU) to mitigate the lack of sparsity and small receptive field problems caused by the segmentation map extraction process in sound event detection with weak labels. In the advent of deep learning framework, segmentation map extraction approaches have shown improved performance in noisy environments. However, these methods are forced to maintain the size of the feature map to extract the segmentation map as the model would be constructed without a pooling operation. As a result, the performance of these methods is deteriorated with a lack of sparsity and a small receptive field. To mitigate these problems, we utilize GLU to control the flow of information and Dilated Convolutional Neural Networks (DCNNs) to increase the receptive field without additional learning parameters. For the performance evaluation, we employ a URBAN-SED and self-organized bird sound dataset. The relevant experiments show that our proposed DCGLU model outperforms over other baselines. In particular, our method is shown to exhibit robustness against nature sound noises with three Signal to Noise Ratio (SNR) levels (20 dB, 10 dB and 0 dB).

• Journal of Korean Society on Water Environment
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• v.24 no.4
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• pp.473-479
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• 2008

Environment problem has been arising in many countries. Especially, soil erosion has been deemed as one of the biggest issues because sediment causes muddy water and pollutants, such as agricultural chemicals, flow in the stream with this sediment. Many studies, regarding soil loss and non-point source pollution from watershed, has been performed while serious problem has been known. Soil loss occurred in most agricultural area by rainfall and runoff. It makes hydraulic structure unstable, causes environmental economical problems because muddy water destroys ecosystem and causes intake water deterioration. As revealing serious effects of muddy water by sediment, many researches have been doing with various methods. Hydraulic structures establishments such as soil erosion control dams and grit chamber are common. Vegetative filter strip is investigated in this study because vegetative filter strip is designed for reducing sediment from upland areas of the watershed, and it has many functions, not only sediment reduction but also runoff water quality improvement and wildlife habitat. With these positive functions of the vegetative filter strip, the study about vegetative filter strip has been increasing for reducing sediment because it is more effective than hydraulic structures from an environmental perspective. But the sediment trapping efficiency by vegetative filter strip, needs to be investigated and designed first. Therefore the model, VFSMOD-W, was used in this study as it can estimate sediment trapping efficiency of vegetative filter strip under various field, vegetation, weather condition. Sensitive factors to sediment trapping efficiency are studied with VFSMOD-W, and sediment trapping efficiency equation has been derived using two most sensitive factors. It is thought that the equation suggested in this study can be used in Soil and Water Assessment Tool (SWAT), to overcome the limit of SWAT filter strip module, which is based solely on filter strip width.

• Journal of the Korean Wood Science and Technology
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• v.27 no.3
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• pp.73-81
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• 1999

This paper was intended to evaluate the effect of the blending condition of pigments on the packing structure of coating color and the interaction between pigments and latices on the optical and interior properties of coated paper. It has been studied many ways to modify the coating structure to induce the interaction among coating components as followings ; 1) to use dispersant for pigment, 2) to control the charge density and the type of surface charge of latex, 3) to support the water retention by adding water retention agent or flow modifier. This paper was performed through the introduction of interaction between pigments which were two kinds of clays and one precipitated calcium carbonate(PCC) and ionic latices of which anionic and amphoteric respectively under the certain blending condition of pigments where their blending ratio of clays to calcium carbonate was 70pph to 30pph. The reason is that packing volume of pigments was highest in that region and thixotropical behavior appears in measuring rheology of coating color. We measured the properties of coating color, interaction with pigments and latex, and properties of coated paper and its printability. As a results, we could find out that amphoteric latex had a great influence on the interaction with pigments, especially clays, no matter what grade and also affected the coating structure significantly in case that this blending condition was 70(clays) to 30(PCC). It produced a powerful effect on the forming of bulky and smooth coating structure and in turn improved the printability of coated paper.

• Journal of Life Science
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• v.25 no.2
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• pp.249-255
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• 2015

Schisandrae fructus [Schizandra chinensis (Turcz.) Baillon] is a medicinal herb widely used for treating various inflammatory and immune diseases in East Asian countries. The Schisandrae Semen essential oil (SSeo) from this plant has pharmacological activities, including antioxidant, antimicrobial, and antitumoral activities. Nevertheless, the biological activities and underlying molecular mechanisms of the potential anti-cancer effects of this oil remain unclear. In the present study, we investigated the potential inhibition of apoptosis signaling pathways by SSeo in human leukemia U937 cells and evaluated the underlying molecular mechanism. Exposure to SSeo resulted in a concentration-dependent growth inhibition due to apoptosis, which was verified by DNA fragmentation, the presence of apoptotic bodies, and an increase in the sub-G1 ratio. Induction of apoptotic cell death by SSeo was correlated with the down-regulation of members of the inhibitor of apoptosis protein (IAP) family (including X-linked inhibitor of apoptosis protein (XIAP), cIAP-1, and surviving) and anti-apoptotic Bcl-2, and with up-regulation of death receptor (DR) 4 and DR5, depending on dosage. SSeo treatment also induced Bid truncation, mitochondrial dysfunction, proteolytic activation of caspase-3, -8 and -9, and concomitant degradation of activated caspase-3 target proteins such as poly (ADP-ribose) polymerase. Taken together, these findings suggest that SSeo may be a potential chemotherapeutic agent for use in the control of human leukemia cells. Further studies are needed to identify its active compounds.

• Journal of the Korean Society of Hazard Mitigation
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• v.6 no.3 s.22
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• pp.69-76
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• 2006

An hydraulic and hydrologic analysis procedure was proposed to reduce the inundation damage of highway in urban stream, that could contribute the EAP and Traffic control planning of Dongbu highway in the Jungrang stream basin which is one of the representative urban area in Korea. We performed the HEC-HMS runoff analysis, and the UNET unsteady flow modeling to decide the inundation reaches and their characteristics. The high inundation risk areas were of Emoon railway bridge and the Wollueng bridge, which are inundated in the case of 10 year and 20 year frequency flood respectively. We also analyze the inundation characteristics under the various conditions of the accumulation rainfall and the duration. Flood elevation at the Wolgye-1 bridge exceed over Risk Flood Water Level(EL.17.84 m) when the accumulation rainfall is over 250 mm and shorter duration than 7 hr. When neglecting backwater effect from the Han river, inundation risk are highly at the reach C2(Wolgye-1 br. ${\sim}$Jungrang br., left bank), C1(Wolgye-1 br. ${\sim}$Jungrang br., right bank), D(Jungrang br. ${\sim}$Gunja br.) in order, but when consider the effect, the inundation risk are higher than the others at the reach D2(Jungrang br. ${\sim}$Gunja br., left bank) and E(Gunja br. ${\sim}$Yongbi br.), which are located downstream near confluence.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.7
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• pp.819-824
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• 2007

The present study describes the cytotoxic effect of Artemisia fukudo extracts. The extract from A. fukudo by 80% ethanol was fractionated with n-hexane, dichloromethane, ethylacetate, and butanol in serial. The cytotoxicity of A. fukudo extracts was examined for its effect on the growth of HL-60 cells by the colorimetric 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium bromide (MTT) assay. In addition, we used the HL-60 cells to see what effects the A. fukudo extracts will have on apoptosis of cancer cells. We checked the cell activity, cell morphologic changes, DNA fragmentation, and DNA content after 24 hr incubation with administering 25 ${\mu}g/mL$ of the A. fukudo extracts. In the treatment of the low concentration of n-hexane and dichloromethane fractions, the survival rate of HL-60 cells is lower than that of the control. The laddering-pattern DNA fragmentation was observed in the treatment with n-hexane and dichloromethane fractions. The DNA content of the cells apoptosis measured as the density of sub-$G_{1}$ hypodiploid cells by flow cytometric analysis. The number of sub-$G_{1}$ hypodiploid cells increased in the treatment with n-hexane and dichloromethane fractions. These fractions obstructed the cell cohesion and caused the blebbing of the cell membrane and fragmentation of the nucleus, both of which are symptoms of apoptosis. These results suggest that A. fukudo has a great potential value as food additives, medicinal supplements for patients with chronic diseases, and preventive measures against cancer.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.10 no.4
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• pp.107-115
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• 2011

Since 2009 The Korean National Police Agency has been pushed "permissive left-turn" forward in order to making progress in Korean traffic operations system. Preceding researches manuals and guidelines present 6 standards(# of accidents # of lanes, pedestrian volume sight # of permissive left-turn lanes vehicle volume) as installation permissive left-turn. But in practical affairs it is most important that secure enough Gap-time between permissive left-turn vehicle and opposite through lane vehicle to make permissive left-turn vehicle move safer and more efficiently. This study suggests applying gap acceptance theory in microscopic model to permissive left-turn installation standards. Analysis methods of this study are field data survey statistical analysis and microscopic simulation analysis. This study collected field data by using AVI recording and measured permissive left-turn vehicle intersection passing time(T1) and against the opposite through lane vehicle Gap-time(T2). And statistical analysis performed about two values that measured before to predict the functionality between T1 and T2. These studies to overcome the limit of sample size carried out a microscopic simulation(VISSIM) plan and collect more samples to input statistical analysis.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.4
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• pp.306-311
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• 2005

Despite advances in surgery, radiotherapy, and chemotherapy, the survival of patients with oral squamous cell carcinoma has not significantly improved over the past several decades. Gene therapy is currently under investigation and shows us new possibility of cancer curing method. This experiment was undergone to find out the cell growth inhibition effect and evidence of apoptosis by HCCS-1(human cervical cancer suppressor-1), one of the candidates of tumor suppressor gene, transducted to human oral cancer cell line. To determine the efficiency of the adenovirus as a gene delivery vector cell line was transducted with LacZ gene and analysed with X-gal staining. Northern blot was performed to confirm the transfection with HSCC-1 gene and cell viability was assessed by cell cytotoxicity assay using cell count kit(CCK). To show the evidence of apoptosis, DNA fragmentation assay and flow cytometry(FACS) were performed. We had successfully construct the recombinant HSCC-1 adenovirus(Ad5CMV-HCCS-1), and importation efficiency was 20% at 2 MOI(multiplicity of infection), 80% at 20 MOI. Northern blot analysis showed that a single 0.6kb mRNA transcript was expressed in Ad5CMV-HCCS-1 transducted cell lines. As a result of CCK, when comparing to control subjects, transducted group showed 50% growth inhibition. In DNA fragmentation assay, according to increasing of MOI, DNA volume was diminished. In FACS analysis, DNA distribution showed fragmentation. This results imply that HCCS-1gene has growth inhibition effect in human oral cancer cell lines through apoptosis induction.

• Journal of the Korean GEO-environmental Society
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• v.9 no.3
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• pp.35-43
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• 2008

This study was carried out to estimate the performance of modified sequencing batch reactor (SBR) process by the application of SBR process for small advanced wastewater treatment plant. Organic, nitrogen and phosphorus were able to remove in the unit reactor by SBR process and it would be able to select the suitable operation method. The plant was operated to achieve high performance with influent control, optimum anoxic/oxic condition using intermediate aeration method, and solid (sludge) /liquid (effluent) separation by modified decanter. The optimum operating mode was 3Cycles a day and intermediate input and aeration. Under these conditions, the treatment efficiencies were good with 60% of designed flow rate and low influent quality. When the influent concentrations of BOD and CODMn were 120.4 mg/L and 95.7 mg/L, respectively. The effluent concentrations of BOD and CODMn were 6.8 mg/L and 11.0 mg/L, respectively. The average removal efficiencies of BOD and CODMn were 94.4% and 88.5%, respectively. The removal efficiencies of T-N and T-P were 69.6% and 73.6%, respectively when the average T-N and T-P concentrations were 32.2mg/L and 4.65mg/L, respectively. The T-N and T-P removal efficiencies were slightly decreased to 58.8% and 68.5%, respectively in the winter season but its were also stable efficiencies. BOD, T-N and T-P were removed by 90%. 67% and 46% respectively in the first anoxic/oxic condition, in addition to T-P was removed by 70% in the second anoxic/oxic condition. From the results, modified sequencing batch reactor (SBR) process is suitable for small advanced wastewater treatment.

• Journal of the korean academy of Pediatric Dentistry
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• v.24 no.4
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• pp.763-770
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• 1997

The air abrasive technique is a non-mechanical method by which teeth are treated before restoration and stains and calculi are removed from tooth surfaces using the kinetic energy of small particles. The air abrasive technique in dentistry was first introduced in the 1950's with as instrument called 'Airdent'. But, as the main restorative materials of the period were amalgam and gold, and the instrument's inability to control the flow of particles caused the particles to be spread throughout the clinics, widespread use was not possible. In the 1990's, as these techincal problems were solved and more interest in new restorative materials rose in an effort to preserve sound tooth structure, new developements took place in instruments related to the air abrasive technique. The air abrasive technique produces less pressure, vibration and heat that might cause patient discomfort and facilitates the preservation of sound tooth structure. It also reduces the need for anesthesia and is less harmful to the pulp. Other advantages include increase in dentin bonding strength of composite resin, lower possibility of saliva contamination and maintenance of a dry field. But there is not direct contact between the nozzle and the tooth, the operator cannot use his or her tactile sense and must rely solely upon visual input. Other disadvantages are: the tooth preparation depends on the operator's ability; alpha-alumina particles, after bouncing off the tooth surface, cause damage to dental mirrors; the equipment is expensive and takes up a certain amount of space in the clinic. The author conducted case report using the air abrasive technique on patient visiting the Department of Pediatric Dentistry at Seoul National University Dental Hospital and arrived at the following conclusions. 1. The tooth preparation capability of different air abrasive devices varied widely among manufacturers. 2. It was more effective in treating early caries lesions and stains compared to lesions where caries had already progressed to produce soft dentin. 3. The cold stream and noise caused by the evacuation system was a major cause of discomfort to pediatric patients. 4. As there is no direct contact with tooth surface when using the air abrasive technique for tooth preparation, considerable experience and skill is required for proper tooth preparation.