• Title/Summary/Keyword: fibril

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A Study on Fibrillation of Tencel Material(Part I) -Based on Change of Properties of Tencel by Cellulase- (텐셀소재의 fibrillation에 관한 연구(제I보) -셀룰라제로 처리한 텐셀의 물성변화를 중심으로-)

  • 정영희;송경헌;양진숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.3
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    • pp.507-515
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    • 2001
  • Tencel is a high quality cellulosic fiber, which is controlled and processed by an environmentally sound route. But, the point about tencel and the reason why it achieves its unique touch in its finished state is that it is a fibrillating fiber. That means it can take a great deal of punishment during the finishing process, which raise the fiber to produce the characteristics handle, without destroying the cloth. The aim of cellulase treatment is to improve appearence of tencel, plus the fiber ends protruding from the fabric surface. But enzymatic hydrolysis can weakens the fiber ends and changes the properties of fabrics. This study examined about the changes of properties according to several conditions and effect of cellulase to fibril of tencel. The results are as follows. The weight loss was occurred, tensile strength was decreased, softness was increased. And cellulase treatment reduced amount of fibril.

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보령제약 중앙연구소 - 연구소 탐방

  • 백우현
    • The Microorganisms and Industry
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    • v.20 no.1
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    • pp.50-52
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    • 1994
  • Ultrastructural observations of mycelial and tissue phase with dimorphic fungal pathogen Coccidioides immitis were studied by electron microscopy of thin sections. 1. In mycelial phase of C.immitis contains normal cell components such as nucleus, mitochondria, endoplamsic reticulum, intracytoplasmic membrane system, cell wall and cell membrane as observed in the other encaryotic cells. 2. In tissue phase of C. immitis was larger than mycelial phase in cell size and observed much more vacuoles than mycelial phase. 3. In the contrast of mycelial phase of C. immitis, the tissue phase of cells were observed fibril form of capsular layer.

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Isolation and Characterization of Chitin from Crab Shell (게 껍질로부터 Chitin의 분리 및 특성 규명)

  • 김성배;박태경
    • KSBB Journal
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    • v.9 no.2
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    • pp.174-179
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    • 1994
  • Chitin was isolated from crab shell wastes and characterized for its chemical and physical properties. White powdered chitin was obtained through demineralizaticn, deproteinization and decoloration process. The contents of inorganics was less than 0.5%, whereas protein and lipid were almost removed. The results of IR spectroscopic analysis for the isolated chitin showed similar characteristics with that of Sigma product. Degree of deacetylation of purified chitin was significantly higher than Sigma product and viscosity average molecular weights was $2.3{\times}10^5~3.2{\times}10^5$. SEM analysis showed that the obtained chitin had the fibril shaped morphology.

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Protein Folding and Diseases

  • Lee, Cheol-Ju;Yu, Myeong-Hee
    • BMB Reports
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    • v.38 no.3
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    • pp.275-280
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    • 2005
  • For most of proteins to be active, they need well-defined three-dimensional structures alone or in complex. Folding is a process through which newly synthesized proteins get to the native state. Protein folding inside cells is assisted by various chaperones and folding factors, and misfolded proteins are eliminated by the ubiquitin-proteasome degradation system to ensure high fidelity of protein expression. Under certain circumstances, misfolded proteins escape the degradation process, yielding to deposit of protein aggregates such as loop-sheet polymer and amyloid fibril. Diseases characterized by insoluble deposits of proteins have been recognized for long time and are grouped as conformational diseases. Study of protein folding mechanism is required for better understanding of the molecular pathway of such conformational diseases.

Accelerating repaired basement membrane after bevacizumab treatment on alkali-burned mouse cornea

  • Lee, Koon-Ja;Lee, Ji-Young;Lee, Sung Ho;Choi, Tae Hoon
    • BMB Reports
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    • v.46 no.4
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    • pp.195-200
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    • 2013
  • To understand the corneal regeneration induced by bevacizumab, we investigated the structure changes of stroma and basement membrane regeneration. A Stick soaked in 0.5 N NaOH onto the mouse cornea and 2.5 mg/ml of bevacizumab was delivered into an alkali-burned cornea (2 ${\mu}l$) by subconjunctival injections at 1 hour and 4 days after injury. At 7 days after injury, basement membrane regeneration was observed by transmission electron microscope. Uneven and thin epithelial basement membrane, light density of hemidesmosomes, and edematous collagen fibril bundles are shown in the alkali-burned cornea. Injured epithelial basement membrane and hemidesmosomes and edematous collagen fibril bundles resulting from alkali-burned mouse cornea was repaired by bevacizumab treatment. This study demonstrates that bevacizumab can play an important role in wound healing in the cornea by accelerating the reestablishment of basement membrane integrity that leads to barriers for scar formation.

Disaggregation Simulation Analysis on Distinct Aβ40 Fibril Models

  • Cho, Tony;Yu, Youngjae;Shin, Seokmin
    • Proceeding of EDISON Challenge
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    • 2016.03a
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    • pp.55-61
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    • 2016
  • $A{\beta}_{40}$ peptides form oligomers that later aggregate into a plaque, which is deemed to be a leading cause of Alzheimer's Disease. Its non-crystalline morphology has limited an understanding of comprehensive structural study. In this research, computational biomolecular simulations were performed in the following order: solvent and ion addition in a box, energy minimization of protein, equilibration, and periodic boundary condition disaggregation of a monomer from fibril. The result founded the two-fold model is 25% more stable in the simulation environment, and the steric zippers held on most tightly until 220 ps of simulation. The study supports the previous findings that two-fold aggregate $A{\beta}_{40}$ is more stable at 310 K and discusses further how much contribution steric-zipper and hydrogen bonding are making.

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Morphology of Styetched Poly(ethylene terephthalate)/ Poly(m-xylene adipamide) Blends (연신된 폴리(에틸렌 테레프탈레이트)/ 폴리(메타-자이렌 아디프아미드) 블렌드의 형태구조)

  • 남주영;박수현;이광희;정지원;박동화
    • Polymer(Korea)
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    • v.27 no.4
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    • pp.313-322
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    • 2003
  • The morphology of poly(ethylene terephthalate) (PET)/poly(m-xylene adipamide) (MXD-6) blends, which was prepared by adding compatibilizer and interchange reaction agent, was investigated. The morphological change in the stretched blend films was also studied. The stretched film showed a dispersed MXD-6 fibril. This fibril became finer with increasing draw ratio (DR). The addition of compatibilizer and interchange reaction agent had no effect on the improvement of interfacial adhesion but caused a defect between the continuous phase and the dispersed phase, leading to the formation of irregular fibril. The change in the superstructure of blends with composition and draw ratio was examined with light scattering (LS). The H$\sub$v/ LS patterns showed a double-cross type pattern consisting of a broad rod-like pattern and a sharp cross streak. On the basis of the model calculation of the H$\sub$v/ pattern, it was found that the appearance of the double-cross type pattern was attributed to the stacking of crystals oriented along the draw direction. The crystals were gradually oriented to the stretching direction with draw ratio. As a result, the high level of orientation was obtained fur the sample of draw ratio is 6.0.

Application of Biofilter Using Fibril-form Matrix for Odor Gas Removal

  • Lee, Gwang-Yeon;Jeong, Gwi-Taek;Lee, Kyoung-Min;Snuwoo, Chang-Shin;Lee, Woo-Tae;Cha, Jin-Myoung;Jang, Young-Seon;Park, Don-Hee
    • 한국생물공학회:학술대회논문집
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    • 2005.04a
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    • pp.247-251
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    • 2005
  • This research was performed for developing of biological treatment process of odor gas such as MEK, $H_{2}S$, and toluene, which is generated from the food waste recycling process. To establish the operational conditions of odor gas removal by small-scale biofiltration equipment, it was continuously operated by using toluene as a treating odor object. When the odor treating microorganisms were adhered to fibril form biofilter, high removal efficiency over 93% was obtained by biofilm formation. At 400 ppm of inlet odor gas concentration and 10 sec of retention time, the removal efficiency was 76% and 93% in 1st stage reactor and 2nd stage reactor, respectively. However, the removal efficiency remained over 97% at the operational conditions above 15 sec of retention time.

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Seed-Conjugated Polymer Bead for ${\beta}2$-Microglobulin Removal at Neutral pH

  • Kim, Mi-Ra;Kang, Sung-Soo;Myung, Eun-Kyung;Ahn, Min-Koo;Choi, Jeong-Hyun;Paik, Seung-R.;Lee, Yoon-Sik
    • Journal of Microbiology and Biotechnology
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    • v.19 no.9
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    • pp.960-965
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    • 2009
  • ${\beta}2$-Microglobulin (${\beta}2m$) is known to be a major factor for dialysis-related amyloidosis. We have studied ${\beta}2m$ removal through an aggregation process, which was initiated by a ligand that could catch the ${\beta}2m$ monomer and promote its aggregation into fibril. As a ligand, we have prepared ${\beta}2m$ fibril fragments and used them as a seed. The seed was coupled to PEGylated-PS beads to remove the monomeric ${\beta}2m$ from solution. The ${\beta}2m$ seed-conjugated resin effectively adsorbed the ${\beta}2m$ monomers with a capacity of 3.6 mg/ml via promoting their aggregation into fibrils on the resin at pH 7.4.