• 가정과삶의질연구
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• 제15권2호
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• pp.155-172
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• 1997

The purpose of this study is to examine the relation between the later personality adjustment types and the elderly percepted conflict with their married children. The subjects for this study are the aged over 60 years in Seoul both having the eldest sons' couples and perceiving their own economics level as the middle-upper. The results based on this are as followed: 1) The Active Integrated Coper is appeared in the higher educational level group in the better health condition in the 11-30 thousand won of personal expense in the professional and management occupation and in the more vigorous for social activity. The Failing Overcoper the Dependent Passive Coper and the Self-negating Undercoper is appeared in th female elder group in the later group of the older age in the lower educational level in the worse health condition in the group without spouse in one without income in the below 10 thousand won in the less preparation for the later life. 2) The problems of emotion and iew of values bring about the conflicts between them and theirs rather than the financial problem. when they are in the worse health condition in the group without religion in the group not cohabiting their eldest sons' couples and in the group not well-prepared for their later life as the socio-demographic variables the old recognized the seriousness of the conflict with their eldest sons' couples. 3) The lower the Active Integrated Coper is and the higher the Failing Overcoper is the more intense the conflict between them and their eldest sons' couples is. 4) The t-test to examine the difference in the old's conflict with their eldest sons' couples among the later groups shows that it is in the less the Active Integrated Coper and in the more the Failing Overcoper that the conflict is more surfaced. 5) The educational level the level of the later life preparation the contact frequency with their daughter the level of their social activity as the socio-demographic variables and the Failing Overcoper as the later personality adjustment type answer for 22 percentage of the conflict.

• 한국임상약학회지
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• 제27권4호
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• pp.214-220
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• 2017

Background: Dapagliflozin is an oral selective inhibitor of sodium-glucose cotransporter 2(SGLT2), the kidney transporter chiefly responsible for glucose reabsorption from the glomerular filtrate. Because this mechanism does not require the action of insulin, dapagliflozin rarely causes hypoglycemia. Dapagliflozin may affect blood glucose control as well as blood pressure and the body weight which are one of the cardiovascular disease risk factors. However, dehydration and ketoacidosis are reported as the side effects of the dapagliflozin treatment and the safety issues have been occurred. The aim of this study is to analyze the effectiveness and adverse events of dapagliflozin in Korean patients. Methods: From December 2014 to August 2015, we retrospectively reviewed the electronic medical records of type 2 diabetes patients who were prescribed dapagliflozin at Severance Hospital. Results: A total of 202 Korean patients were enrolled in this study. The effectiveness in the reduction of blood glucose was statistically significant(p<0.001). Dapagliflozin decreased 0.74% of HbA1c after 24 weeks. Significantly more participants achieved the target HbA1c level(HbA1c<7%) after 24 weeks(n=42, 35.3%) than before taking dapagliflozin(n=21, 17.6%). Blood pressure decreased 5.7 mmHg systolic blood pressure(SBP), 1.9 mmHg diastolic blood pressure(DBP) after 24 weeks. More than one quarter of participants(n=35, 29.4%) experienced weight loss. Most common adverse event was genitourinary symptoms. Conclusion: In this study, the effectiveness of dapagliflozin in improving glycemic control, blood pressure control, and weight loss was statistically significant. However, elderly and female patients, who have higher incidence of adverse events, should use dapagliflozin cautiously.

• 대한한방내과학회지
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• 제32권3호
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• pp.371-386
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• 2011

Background : Vertigo is a very common complaint in clinical practice. The number of patients who complain of vertigo has been increasing due to rapid growth of the elderly population. This study was designed to review the clinical features and success of oriental medical treatment of positional vertigo. Methods : This observation was made on 70 subjects diagnosed with positional vertigo. They were hospitalized in the Semyung University Oriental Medicine Hospital. Results : The results were as follows 1. Female patients (82.9%) were more than male patients. The most common age group was 8th decade and the patients rapidly increased after the 5th decade of age. 2. The most common past history of positional vertigo was hypertension, the second was cerebral infarction, and the third was hyperlipidemia. 3. In the oriental medicine diagnosis, phlegm-dampness syndrome (痰濕交阻 眩暈) was the most common disease (92.9%), and in western medicine, BPPV was the most (82.9%). 4. In herbal medication, Banhabaekchulchunma-tang gami (45.7%) was the most commonly used, the second being Taeksa-tang (30%). 5. The vertigo score of 94.3% patients improved and none got worse. 6. In general characteristics, men over 64 years improved best. Past history had no effect on the improvement of vertigo. 7. The sooner patients visited hospital after onset, the shorter hospitalization time was. Conclusions : Vertigo attacks patients well in advanced age, with various causative diseases. Oriental medical treatments have considerable effects on positional vertigo, especially treated with Banhabaekchulchunma-tang gami and Taeksa-tang.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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• pp.1102-1109
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• 1993

This paper describes the research and development of Walking Tractors and Tillage Implements for Phase I (1991-1992) . The project consists of : (1) the study and need for the development of the walking tractors for Thailand and other Southeast Asian countries ; (2) the comparison in the use of the walking tractors and their transmission systems that are made in Thailand and aborad : and (3) the design of future walking tractors for Asian farmers in developing countries. The design of the walking tractors is concentrated to provide the ease to farmers, especially the elderly and female which will play an important role in the future agriculture of Thailand due to the lack of manpower. In addition , the design of the walking tractors is also aiming for small-scale farmers, the majority that have limited land capital. The walking tractors consist of several components but the most important one is the " Transmission System" . Thus, the research is concentrated in the devel pment an design of the a new transmission system. The new machine , currently developed, is named after the Chulalongkron University as " Chular Walking Tractor " , model SPJS -60. The tractor uses a 6-7 horsepower diesel engine with three forward gears and one reverse gear. The tractor also uses the latest gearing technology so called planetary gearing system with steering clutches system that never been used in any earlier model. The advantages of the planetary gearing system are : (1) the final drive gear can be small, and can be designed to provide higher strength with less wearing resistance, (2) the system eliminates a shaft which is used in other systems, thus reduces the weight and the manufacturing cost . Furthermore, the Chular Walking Tractor has an additional power take off shaft that can be used or linked with other standard agricultural implements.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1375-1379
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• 2014

Background: Differences in clinicopathological characteristics of gastric cancer (GC) between young and older patients are controversial and a matter of debate. Determining the statistical significance of clinicopathological information with respect to age might provide clues for better management and treatment ofGC. Materials and Methods: A total ofl03 Indiao GC patients were enrolled for study and specimens were classified according to the AjCC-TNM system. Patients were grouped into two age-wise categories, young patients (<40 years; n=13) and older patients (${\geq}40$ years, n=90). The clinicopathological features of both groups were retrospectively examined and compared. p53 alterations were analyzed by polymerase chain reaction-single strand conformational polymorphism and immunohistochemistry methods at gene and protein levels respectively. The cases were considered p53 over-expressed if it was present in more than 25% of the tumor cells and p53 alterations was correlated with the clinicopathological characteristics of the patients as well as etiological factors for GC in both groups. Results: We found significant association of young patients with cancer stage (p=0.01), and very strong association with histology grade (p=0.064) and poorly differentiated (p=0.051) state of GC. However, neither young nor elderly patients showed associations with location, gender, etiological factors and p53 expression and alteration. Overall the male-to-female ratio of GC patients was 3.12 and the value was higher in the young (5.5) than in the older group (2.91). Conclusions: Clinicopathological features of GC like caocer stage, cell differentiation and histological grades were significantly different among young and old age cohorts. We observed a male predominance among the young group that decreased significantly with advancing age. More awareness of GC onset is required to detect cancer at an early stage for successful treatment.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2473-2476
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• 2014

Background: Little is known about the cancer screening prevalence and correlates in older adults from different racial backgrounds. In the context of heightened efforts for prevention and early diagnosis, we collected information on screening for two major types of cancers: cervical and breast cancer in order to establish their prevalence estimates and correlates among older South African women who participated in the Study of Global Ageing and Adults Health (SAGE) in 2008. Materials and Methods: We conducted a national population-based cross-sectional study with a multi-stage stratified cluster sample of 3,840 individuals aged 50 years or older in South Africa in 2008. In this analysis, we only considered the female subsample of (n=2202). The measures used included socio-demographic characteristics, health variables, anthropometric and blood pressure measurements. Multivariable regression analysis was performed to assess the association of socio-demographic factors, health variables and cancer screening. Results: Overall, regarding cervical cancer screening, 24.3% ever had a Papanicolaou (PAP) smear test, and regarding breast cancer screening, 15.5% ever had a mammography. In multivariate logistic regression analysis, younger age, higher education, being from the White or Coloured population group, urban residence, greater wealth, and suffering from two or more chronic conditions were associated with cervical cancer screening, and higher education, being from the White or Indian/Asian population group, greater wealth, having a health insurance, and suffering from two or more chronic condtions were associated with breast cancer screening. Conclusions: Cancer screening coverage remains low among elderly women in South Africa in spite of the national guideline recommendations for regular screening in order to reduce the risk of dying from these cancers if not detected early. There is a need to improve accessibility and affordability of early cervical and breast cancer screening for all women to ensure effective prevention and management of cervical and breast cancer.

• Journal of Chest Surgery
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• 제47권5호
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• pp.451-457
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• 2014

Background: The balance of the risks and the benefits of cardiac surgery in the elderly remains a major concern. We evaluated the early and mid-term clinical results of patients aged over 75 years who underwent major cardiovascular surgery. Methods: Two hundred and fifty-one consecutive patients, who underwent cardiac surgery at Seoul National University Bundang Hospital between July 2003 and June 2011, were included in this study (mean age, $78.7{\pm}3.4$ years; male:female=130:121). Elective surgery was performed in 112 patients, urgent in 90, and emergency in 49. Results: Early mortality was 12.7% (32/251). Follow-up completion was 100%, and the mean follow-up duration was $2.8{\pm}2.2$ years. Late mortality was 24.2% (53/219). There were 283 readmissions in a total of 109 patients after discharge. However, the reason for readmission was related more to non-cardiac factors (71.3%) than to cardiac factors. The overall survival estimates were 79.2% at the 1-year follow-up and 58.4% at the 5-year follow-up. Patients who underwent elective surgery had a lower early mortality rate (elective, 4.5%; urgent, 13.3%; emergency, 30.6%) and better overall survival rate than those that underwent urgent or emergency surgery (p<0.001). Conclusion: The timing of cardiac surgery was found to be an independent risk factor for early and late mortality. Thus, earlier referral and intervention may improve operative results. Further, comprehensive coordinated postoperative care is needed for other comorbid problems in aged patients.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.793-796
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• 2015

Background: Chronic lymphoid leukemia (CLL) is not an uncommon hematological malignancy which primarily affects elderly individuals. It is more common in developed world than in developing countries. The rational of this study was to determine the clinico-hematological profile in Pakistan. Materials and Methods: In this prospective cross sectional study, sixty patients with CLL were enrolled from January 2011 to June 2013. Data were analyzed with SPSS version 21. Results: The mean age was $59.0{\pm}9.2years$ (range 40-82) and the male to female ratio was 2.1:1. Peak age group was 60-70 years (38.3%) and 18.3% were under 50 years old. Major complaints were weakness (51.7%), fever (18.3%) and abdominal discomfort (13.3%). Main clinical findings were splenomegaly (46.6%), lymphadenopathy (36.6%) and pallor (26.7%). Some 16.7% were diagnosed incidentally. The mean hemoglobin was $10.8{\pm}2.4g/dl$, with a total leukocyte count of $91.5{\pm}87.8{\times}10^9/l$ and platelets $197.8{\pm}103.2{\times}10^9/l$. Anemia and thrombocytopenia were seen in 26.7% and 21.7% of cases, respectively. High LDH and hyperuricemia were detected in 15% each and elevated serum creatinine was seen in 11.6%. According to Rai staging 11.6% were in stage 0, 13.3% stage 1, 26.7% each for stage II and stage III while 21.7% patients were in stage IV. Conclusions: CLL in our patients in Pakistan, unlike in the West, is seen in a relatively young population with male predominance. Primarily disease is of B-cell origin and about 2/3 of the patients present at advanced stage.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8629-8631
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• 2016

Background: Primary idiopathic myelofibrosis (PMF) is a clonal Philadelphia chromosome-negative myeloproliferative neoplasm characterized by extramedullary hematopoiesis and marrow fibrosis. It is an uncommon hematopoietic malignancy which primarily affects elderly individuals. The rational of this study was to determine its clinico-epidemiological profile along with risk stratification in Pakistani patients. Materials and Methods: In this retrospective cross sectional study, 20 patients with idiopathic myelofibrosis were enrolled from January 2011 to December 2014. Data were analyzed with SPSS version 22. Results: The mean age was $57.9{\pm}16.5years$ with 70% of patients aged above 50. The male to female ratio was 3:1. Overall only 10% of patients were asymptomatic and the remainder presented with constitutional symptoms. In symptomatic patients, major complaints were weakness (80%), weight loss (75%), abdominal discomfort (60%), night sweats (13%), pruritus (5%) and cardiovascular accidents (5%). Physical examination revealed splenomegaly as a predominant finding detected in 17 patients (85%) with the mean splenic span of $22.2{\pm}2.04cm$. The mean hemoglobin was $9.16{\pm}2.52g/dl$ with the mean MCV of $88.2{\pm}19.7fl$. The total leukocyte count of $17.6{\pm}19.2{\times}10^9/l$ and platelets count were $346.5{\pm}321.9{\times}10^9/l$. Serum lactate dehydrogenase, serum creatinine and uric acid were $731.0{\pm}154.1$, $0.82{\pm}0.22$ and $4.76{\pm}1.33$ respectively. According to risk stratification, 35% were in high risk, 40% in intermediate risk and 25% in low risk groups. Conclusions: The majority of PMF patients were male and presented with constitutional symptoms in our setting. Risk stratification revealed predominance of advanced disease in our series.

• 디지털융복합연구
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• 제12권6호
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• pp.539-547
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• 2014

본 논문은 청소년의 스트레스와 자살생각간의 관계에서 희망의 매개효과를 파악하는데 연구 목적이 있다. 이를 위해 2010년 5월부터 8월 사이에 청소년 399명을 대상으로 전국 10개 도시에서 설문조사를 하였다. 주요 연구결과를 살펴보면, 첫째, 청소년의 스트레스는 자살생각과 정적인 상관관계를 보였고, 희망은 자살생각과 부적인 상관관계를 나타냈으며 스트레스가 희망보다도 자살생각에 더 높은 효과를 주는 것으로 나타났다. 둘째, 청소년의 자살생각은 2점이 되지 않아 낮은 편이라 할 수 있고 스트레스는 중간수준이며, 희망인 경로사고와 주도사고는 보통 이상의 수준이었다. 셋째, 청소년의 스트레스와 자살생각과의 관계에서 희망의 경로사고와 주도사고가 매개되었다. 즉 스트레스로 인해 자살생각이 높다 해도 경로사고와 주도사고가 높은 경우 그렇지 않은 경우에 비해 자살생각은 낮았다. 마지막으로 본 연구에서 자살생각에 서 가장 취약한 집단으로 나타난 대도시 및 중소도시에 거주하는 여고생의 스트레스와 자살생각간의 관계에서 주도사고는 매개효과가 검증되었으나 경로사고는 검증되지 않았다. 청소년의 자살을 예방하고 감소시키기 위한 정책적 함의를 제언하였다.