Ray, Sujit Kumar;Macoy, Donah Mary;Kim, Woe-Yeon;Lee, Sang Yeol;Kim, Min Gab
Molecules and Cells
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v.42
no.7
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pp.503-511
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2019
As sessile organisms, plants have developed sophisticated system to defend themselves against microbial attack. Since plants do not have specialized immune cells, all plant cells appear to have the innate ability to recognize pathogens and turn on an appropriate defense response. The plant innate immune system has two major branches: PAMPs (pathogen associated molecular patterns)-triggered immunity (PTI) and effector-triggered immunity (ETI). The ability to discriminate between self and non-self is a fundamental feature of living organisms, and it is a prerequisite for the activation of plant defenses specific to microbial infection. Arabidopsis cells express receptors that detect extracellular molecules or structures of the microbes, which are called collectively PAMPs and activate PTI. However, nucleotidebinding site leucine-rich repeats (NB-LRR) proteins mediated ETI is induced by direct or indirect recognition of effector molecules encoded by avr genes. In Arabidopsis, plasmamembrane localized multifunctional protein RIN4 (RPM1-interacting protein 4) plays important role in both PTI and ETI. Previous studies have suggested that RIN4 functions as a negative regulator of PTI. In addition, many different bacterial effector proteins modify RIN4 to destabilize plant immunity and several NB-LRR proteins, including RPM1 (resistance to Pseudomonas syringae pv. maculicola 1), RPS2 (resistance to P. syringae 2) guard RIN4. This review summarizes the current studies that have described signaling mechanism of RIN4 function, modification of RIN4 by bacterial effectors and different interacting partner of RIN4 in defense related pathway. In addition, the emerging role of the RIN4 in plant physiology and intercellular signaling as it presents in exosomes will be discussed.
In this paper, conceptual structural design of the main wing for a small scale WIG(Wing in Ground Effect) among high speed ship projects, which will be a high speed maritime transportation system for the next generation in Rep. of Korea, was performed. The Carbon/Epoxy material was selected for the major structure, and the skin-spar with a foam sandwich structural type was adopted for improvement of lightness and structural stability. As a design procedure for the present study, firstly the design load was estimated through the critical flight load case study, and then flanges of the front and rear spars from major bending loads and the skin and the spar webs from shear loads were preliminarily sized using the netting rule and the rule of mixture. Stress analysis was performed by a commercial FEA code, NASTRAN. From the stress analysis results for the first designed wing structure, it was confirmed that the upper skin between the front spar and the rear spar was unstable fer the buckling. Therefore in order to solve this problem, a middle spar and the foam sandwich type structure at the skin and the web were added. After design modification, the structural safety and stability for the final design feature was confirmed. In addition to this, the insert bolt type structure with eight high strength bolts to fix the wing structure to the fuselage was adopted for easy assembly and removal as well as in consideration of more than 20 years fatigue life.
Cheol-Hoon Kim;Dong-Han Jung;Young-San Kim;Hyo-Jo Lee
Journal of the Korea Society of Computer and Information
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v.29
no.2
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pp.119-126
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2024
The IISS(Integrated Interface Storage System) software performs the function of transmitting tactical domain messages of Combat Management System for interface analysis of Naval Combat System. The source code is relatively large because the IISS software handles most messages. The modifications of source code of the IISS software occur frequently due to changes in interconnected equipment and messages. Therefore, additional effort and cost are required during the development process. In this paper, we studied standardization of the IISS software to improve reusability. Through the feature model, the components of the IISS software were divided by function and modification elements were separated. And the structure of the IISS software was improved by applying design patterns. As a result, it was possible to minimize modifications of the IISS software by changes in interconnected equipment and messages and a reduction in development costs could be expected.
Journal of the Korea Society of Computer and Information
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v.29
no.8
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pp.201-208
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2024
This study aimed to improve the EPL education platform, Rewond (rewond.com), which was built as a prototype, into an EPL educational tool based on Embodied Cognition. In the first phase, the heuristic evaluation, five experts were selected to evaluate the subject using evaluation items that included learning principles of Embodied Cognition. Based on the evaluation results, debriefing session analysis, and consultations with co-researchers, three improvement points were identified and specific modification plans were proposed. During the beta version development phase, the co-researchers implemented an increase in coding content, provided help for each content, and added a feature that allows progression to the next learning stage upon completion of the previous one. In the final usability testing phase, the usability of the beta version was tested with ten fourth-grade elementary school students.
Journal of Korean Library and Information Science Society
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v.24
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pp.413-448
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1996
Nowadays, the World Wide Web (WWW) has become an important resource of timely information for the information-related people such as information scientists, librarians, and students in Library and Information Sciences area. They are information professionals who navigate the information on the internet. Also, they need to be information providers who build a WWW homepage. This paper is a study of the necessity, preparation, and building WWW Homepage files for school of Library and Information Sciences in the age of competition among disciplines. It is particularly focused on the colleges and universities in Republic of Korea (ROK) and North America area. The purpose of this study is to provide various kinds of reference information to prepare a homepage in the future as utilizing information on the internet effectively. Even though a Web page was necessary for a school of Library and Information Sciences to show news, and introduce the purpose of the disciplines and the curriculum of the school, and the professors of a class etc., it was not well-prepared yet in ROK. However, a web page was used well enough and prosperous in North America area (Canada, the United States, and Puerto Rico) comparatively. Those web pages were analyzed and studied to prepare for a good designing of homepages for school of Library and Information Sciences in Korea and for the age of competition among disciplines in this paper. Suggestions for designing a good homepage and guidelines for preparing a best one were studied after both reviewing literature and utilizing experiences by the author who currently serves in the School of Library and Information Sciences in Keimyung University and builds homepage for the school. As a result, the major suggestions are ; premiered, and they are as follows: (1) English version of a homepage is necessary, (2) Provide a multimedia presentation about the nature of a school (3) Incorporate a place to let people make suggestions on the contents (of a homepage), (4) Bear in mind that potential users must be familiar with abbreviations you used, (5) Absolutely do not use abbreviations that may make the content more difficult to understand, (6) Add a feature on the every single page that will take the user back to the main page, (7) Use clear, short and well-structured sentences and remember to divide text into paragraphs, (8) Date with a creation or modification date in the homepage to indicate the updated date, (9) Being a multimedia environment, use colors effectively (the guidelines were also suggested), and (10) Put colleges' name into the title of bookmarks to find out them easily.
Latent topic models are statistical models which automatically captures salient patterns or correlation among features underlying a data collection in a probabilistic way. They are gaining an increased popularity as an effective tool in the application of automatic semantic feature extraction from text corpus, multimedia data analysis including image data, and bioinformatics. Among the important issues for the effectiveness in the application of latent topic models to the massive data set is the efficient learning of the model. The paper proposes an accelerated learning technique for PLSA model, one of the popular latent topic models, by an incremental EM algorithm instead of conventional EM algorithm. The incremental EM algorithm can be characterized by the employment of a series of partial E-steps that are performed on the corresponding subsets of the entire data collection, unlike in the conventional EM algorithm where one batch E-step is done for the whole data set. By the replacement of a single batch E-M step with a series of partial E-steps and M-steps, the inference result for the previous data subset can be directly reflected to the next inference process, which can enhance the learning speed for the entire data set. The algorithm is advantageous also in that it is guaranteed to converge to a local maximum solution and can be easily implemented just with slight modification of the existing algorithm based on the conventional EM. We present the basic application of the incremental EM algorithm to the learning of PLSA and empirically evaluate the acceleration performance with several possible data partitioning methods for the practical application. The experimental results on a real-world news data set show that the proposed approach can accomplish a meaningful enhancement of the convergence rate in the learning of latent topic model. Additionally, we present an interesting result which supports a possible synergistic effect of the combination of incremental EM algorithm with parallel computing.
Headache is a symptom with varied etiologies and extraordinarily frequent. Headaches can be a symptom of another diseases, such as meningitis, subarachnoid hemorrhage or brain tumor, may represent the disease entity itself as the case in migraine. The international Headache Society criteria were the first to distinguish between primary and secondary headache disorders. When evaluating a patient who presents with headache, the physician abviously needs to identify or exclude the myriad conditions that can cause secondary headache and initial diagnostic workup should be considered. If patient meets the criteria for a primary headache disorder, treatment commonly initiated without additional neurodiagnostic tests. The headache type, its associated feature, and the duration and the intensity of the pain attack all can influence the choice of acute therapy in migraine. Pharmacologically, such as NSAIDs, combination analgesics, vasoactive antimigraineous drugs, neuroleptics, antidepressants, or corticosteroids. Other approches to managing headache include a headache diary to identify triggers, biofeedback, relaxation technique and behavioral modification. Daily preventive medication should be considered by his attack frequency and intensity, and maintained for 4 to 6 months. Tension-type headaches are distinguished between episodic and chronic tension-type headache, but physician must make sure that patient is not drug-overuse or independent during symptomatic abortive therapy or preventive medication. The most difficult headache patients to treat are those with chronic daily headache. They often have physical dependency, low frustration tolerance, sleep problems, and depression. So discontinuation of overused medication is crucial. New developments in migraine therapy are broadening the scope of abortive and prophylactic treatment choices available to the physician. The enhanced ease of the use of sumatriptan and DHE will likely increase patient compliance and satisfaction.
Journal of the Korean Society of Propulsion Engineers
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v.15
no.2
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pp.62-67
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2011
Launching tube is a kind of case to protect the guided weapons from external environments and conducted as a guide when they are fired. The guided weapons have been firmly kept at the launching tube and transferred, and would be separated at the required time when they are fired To meet the aim, it has been used explosive bolts which are reliable and efficient mechanical fastening devices having the special feature of a built-in release. The disadvantage of explosive bolt lies in that it is based on the high explosive effect of a pyrotechnic charge. When the explosive bolt is ignited, there are some bad effects; a flame, fragments and pyro-shock. Because of these bad effects there are many restriction to use bolt as joining devices to precision guided weapons. To solve these problems, the aim of the present work is to invent the ball-type separation bolt which is a pyrotechnically releasable mechanical linking device for two mechanical elements that does not suffer from such drawbacks. A standard pressure cartridge can moreover be easily integrated inside the device according to the present work and this with no modification to its structure. The present work was represented quantitatively the margin of separation safety and analysed separation mechanism in ball type separating bolt to perform the dynamic separation test.
This study try to analyze feature of model creation and model developing process for gifted students and the activity of students and teachers affected those processes in scientific model constructing class for phase change of moon. For this, I teach scientific model constructing class for science gifted students. I shoot video and record the voice for whole class and each group activity, have a face-to-face talk for selected group members, analyze the paper of activities. I reconstruct model creation and model developing process for each groups and each students, draw a influence that activity aspects of the students and role of the teacher affected modelling process based on those data. After analyzing, I find that discussion in the group contribute model creation and model developing process and developing process of each model changed according to the similarity between target model and first model. The more the students actively participate group activities, the more first model is diversified and final model is more elaborated. Also, the teacher influence model creation and developing process.
The National Base Map construction consists of the regular correction work of dividing the whole country into two regions and carrying out the modification Plotting by aerial photographs every two years as well as the real time updating work of correcting the major change feature within two weeks by the field survey and the As-Built Drawing. In the case of the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS) used for real time updating work of the National base map, the coordinate transformation error is included in the positional error when applied to the National Base Map based on the World Geodetic Reference System as the coordinate system based on the Regional Geodetic Reference System. In addition, National Base Map is registered based on the outline(eaves line) of the building in the Digital Topographic Map, and the Cadastral and Architecture are registered based on the building center line. Therefore, the Building Object management standard is inconsistent. In order to investigate the improvement method, the network RTK survey was conducted directly on a location of the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS) and the problems were analyzed by comparing with the plane plotting position reference in National Base Map. In the case of the general structure with the difference on the Building center line and the eaves line, beside the location information was different also the difference in the ratio of the building object was different between Building center line and the eave. In conclusion, it is necessary to provide the Base data of the double layer of the Building center line and the outline of the building(eaves line) in order to utilize the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS). In addition, it is necessary to study an organic map update process that can acquire the up-to-dateness and the accuracy at the same time.
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