• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.2
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• pp.345-351
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• 2010

Alcoholic hepatitis is an acute and severe liver disease associated with high mortality rate. This study was conducted to develop the instrument of criterion for symptoms improvement after temperance. We made the symptoms improvement questionnaire for alcoholic hepatitis patients through reviewing traditional oriental medical literatures and got advices from the advisor committee with delphi technique. The advisor committee on this study was organized by 10 professors of internal medicine of oriental medical colleges nationwide. The questionnaire was composed of questions about 10 symptoms - fatigue, pain, anorexia, abdominal bloat, heaviness of the body, itch, nausea, sleep, dryness in the mouth and stools. We named it Alcoholic Hepatitis Symptoms Improvement Questionnaire(AHSIQ). We surveyed 65 male alcoholic hepatitis patients and checked liver function profile and AHSIQ before and after temperance four times for six weeks. As a result of factor analysis the scales of AHSIQ had content validity and construct validity. And internal consistency reliability was good(Cronbach's alpha=0.768-0.871). The total scale scores were statistically significant in gamma-GTP related validity. We suggest that AHSIQ would be effective for measuring symptoms improvement degree in alcoholic hepatitis patients through further investigations with larger clinical trials.

• Toxicological Research
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• v.31 no.2
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• pp.173-180
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• 2015

Extract from Gryllus bimaculatus crickets inhibits oxidation at the DNA level, with reduced production of 8-hydroxy-2'-deoxyguanosine (8-OHdG). Microarray analyses were performed with a rat 28K cDNA clone set array to identify the gene expression profiles of aged (10 months old) Wistar Kyoto rats treated for one month with 100 mg/kg G. bimaculatus ethanol extract to assess the effects. The extract produced a meaningful anti-edema effect, evident by the inhibition of creatinine phosphokinase activity. The weights of abdominal and ovarian adipose tissues were reduced and the proportion of unsaturated fatty acids in adipose tissues was increased in an extract dose-dependent manner. Compared with untreated control rats, rats treated with the extract displayed the upregulation of 1053 genes including Fas (tumor necrosis factor receptor superfamily, member 6), Amigo3 (adhesion molecule with an immunoglobulin-like domain), Reticulon 4, 3-hydroxy-3-methylglutaryl-coenzyme (Hmgcr; a reductase), related anti-fatigue (enzyme metabolism), and Rtn antioxidant, and the downregulation of 73 genes including Ugt2b (UDP glycosyltransferase 2 family), Early growth response 1, and Glycoprotein m6a. Data suggest that G. bimaculatus extract may have value in lessening the effects of aging, resulting in a differential gene expression pattern indicative of a marked stress response and lower expression of metabolic and biosynthetic genes.

• Journal of Korean Physical Therapy Science
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• v.19 no.4
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• pp.53-59
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• 2012

Background : The purpose of the study was: to investigate muscle activation of upper arm according mouse shape. Methods : Twenty person(mean age : 23. 7) who have healthy condition was participated this study, we collected data of muscle activation using by EMG from upper trapezius(Tr), deltoid middle fiber(De), extensor digitorum(Ed), first dorsal interosseous(Di) during participants was performed click and drag according various mouse. Mouse shape was divided 4 level as follow shape 1 was very small, 2 was small, 3 was moderate, 4 was large. Data was analyzed ANOVA, independent t-test using by SPSS ver18.0. Results : There was significantly difference of muscle activation among each muscle according mouse shape in drag and click. In shape 1, 4, there was significantly difference of muscle activation of Tr, De, Ed between drag and click except Di. In shape 2, 4, there was significantly difference of muscle activation of all muscle between drag and click. Conclusion : We knew that extensor digitroum showed more higher muscle activation than other muscle in drag, first dorsal interoseous showed more higher muscle activation that other muscle in click. We suggest that mouse shape was very important factor in order to prevent skeletal muscular disorder for computer user, and mouse shape can reduce muscle fatigue during computer work.

• Journal of Industrial Convergence
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• v.18 no.1
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• pp.97-107
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• 2020

Since long ago, there has been a saying that "Drink water to quench thirst, drink alcohol to remove anguish and anxiety, and drink tea to recover from fatigue and refresh mind." Tea is really better for body and mind than water when it is drunken long and is valuable Jinda(眞茶) given by mother nature. In particular, curing tea reflecting characteristics of climate changes in all seasons helps in keeping health. Since tea contains the Yin-Yang system, which is a philosophical ideology of ancient people, old predecessors knew which tea they should brew and drink for curing in harmony with Yin and Yang. As a factor that influences component changes of tea, a complex interaction of heaven, earth and man is important and especially, mind of a person to handle tea is most important. Tea is a natural curing drink, which plays a role as a bridge between humans and nature.

• Journal of muscle and joint health
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• v.9 no.2
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• pp.135-143
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• 2002

Exercise is an important strategy for health promotion in patients having osteoarthritis. But, lots of patients with osteoarthritis were underexercised. Exercise pattern and influencing factors of exercise barrier are not well-known. To address this issue, we studied the exercise pattern and influencing factors of exercise barrier in patients with osteoarthritis. The subjects of the study were 463 adult osteoarthritis (Mean age = 61.63 years) who had diagnosed osteoarthritis by rheumatologist. Data were gathered from May 1999 to February 2000 using a questionnaire and exercise barrier(Sallis et al, 1989), exercise pattern(Lee et al., 2000), physical status by WOMAC(Bellamy, 1989), socail support(Sallis et al., 1989), fatigue and pain using graphic rating scale, depression by CES-D(Radloff,1977). Data were analyzed with the SPSS win 6.0 using frequency, ANOVA, Stepwise multiple regression. The results of this study were as follows; 1) 56.4% of sample was 'do not exercise at all', 'longer rest than exercise', was 15.9%, 'longer exercise than rest' was 7.2%, 'exercise regularly' was 20.5%. 2) Social support (F=10.349, p=0.000) and exercise barrier(F=4.455, p=0.004) were showed significantly difference by exercise pattern. 3) Influencing factors of exercise barrier were depression and social support. Thoses explained 13.3% of exercise barrier. In conclusion, half of osteoarthritis patient did not do exercise and it was shown that depression and social support were major influencing factors to exercise barrier. The results of this study can be applied to develop the health promoting educational program for patients with osteoarthritis.

• The Journal of Korean Society for Radiation Therapy
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• v.6 no.1
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• pp.154-170
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• 1994

The Purpose of this study was to determine the degree and contents composing the qualify of life and to analyze the relationships among the demographic characteristics, the degree of pain and the quality of life of the cancer patients experiencing a radiation therapy. The subjects for this study were 110 out-patients experiencing a radation therapy at C University Hospital in K-city, from April to October, 1992. The data were obtained using a convenience sampling technique. The tool of this study was the quality of life scale developed by Ro, You-Ja and the data were analyzed using a SAS program for percentages, mean & standard deviation. ANOVA and Scheffe test. The results were as follows : 1. the average total score of the quality of life of the subjects was 139.65(minimum score 121-maximum score 164), item mean score grange 1-5) was 2.97. For each factor in the quality of life scale, the mean scores (range 1-5) were 3.29 in emotional state, 3.14 in relationship with neighbors. 3.04 in physical state and function. 2.92 in self-esteem, 2.81 in economic life and 2.65 in relationship with family. 2. The incidence of physical symptoms was seen fatigue ($84.5\%$). anorexia ($65.5\%$) and weight loss ($47.3\%$) in order. The 50.9 percentage of the subjects complained of moderate or severe pain. 3. The results of the analysis of the relationships between the demographic variables and the quality of life were as follows : Gender (F=8.45, P=0.0044), age (F=6.29, P=0.0001). educational level (F=5.67, P=0.0046), marital status (F=6.82. P=0.0016), occupation (F=2.86, P=0.009), monthly income (F=6.90, P=0.0003), family living together (F=3.95, P=0.0494) and person paying a medical fee (F=5.14, P=0.0023). 4. The relationship between the degree of pain and the quality of life was significant difference (F=3.12, P=0.0482).

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.406-413
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• 1997

근전도(EMG:Electromyogram)를 사용하여 국부 근육 피로(Localized Muscle Fatigue)를 정량화으로 분석 하기 위해 널리 이용되고 있는 AR(Autoregressive)모델의 1차 계수, RMS(Root Mean Square), ZCR(Zero Crossing Rate), MPF(Mean Power Frequency), MF(Median Frequency)를 선택하여, 근육이 발휘하는 힘과 시간의 흐름에 따라 근육 피로의 정도를 민감하게 나타내는 매개변수를 규명하였다. 피실험자 10명의 좌우 척추세움근(Erector Spinae Muscle)을 대상으로 등장수축(Sustained Isometric Contraction)조건에서 허리의 신전(Extension)운동을 실시하였다. 이때 발휘해야 하는 힘의 수준은 15%, 30%, 45%, 60%, 75% MVC 로 정하였고 각 수준마다 20초 동안 근전도를 측정하 였다. 데이터 분석은 총20초 구간의 근전도를 0.5초 간격으로 나누어 매개변수들을 각각 구하고 분석을 실시하였다. 시간의 흐름에 대한 피로도 분석 결과, AR 모델의 1차 계수와 MPF가 유의한 차이를 보였으며, 낮은 수준의 %MVC에서는 AR 계수가, 높은 수준에서는 MPF가 민감한 반응 결과를 나타냈다. 그리고 근육이 발휘하는 힘의 정도를 분석하기 위해 주로 사용되고 있는 RMS 보다는 더 AR 계수가 모든 수준에서 뚜렷하게 차이를 보인 것이 확인되었다. 따라서 AR 모델의 1차 계수가 근육의 피로 정도와 힘의 수준을 다른 매개변수에 비해 더욱 민감하게 구별함이 입증되었다. 이러한 결과는 다른 분야에서도 근육 피로를 정량적으로 측정하는데 사용될 수 있을 것으로 생각되며, 개인적 변이도를 고려한 확률 기법을 사용한다면 보다 정확한 근전도 분석이 이루어질 것으로 기대된다.있음을 알 수 있었다. 사료된다.의 결과는 자전거 에르고노미터의 결과가 트레드밀의 결과에 87.60%정도 나타났다.음을 관찰하였다. 특히 vitamin C와 E의 병용투여는 상승적으로 적용하여 간세포손상을 더욱 억제시킴을 알 수 있었다.mance and on TFP(Total Factor Productivity) growth which is a pure measure of firm performance. To utilize the advantage of panel data, FEM(Fixed Effect Model) and REM(Random Effect Model) were used. The empirical result shows that the entropy index as a measurement of inter-business relatedness is not significant but technological relatedness index is significant. OLS estimates on pooled data were considerably different from FEM or REM estimates on panel data. By introducing interaction effect among the three variables for business portfolio properties, we obtained three findings. First, only VI (Vertical integration) has a significant positive correlation with ROS. Second, when using TFP growth as an dependent variable, both TR(Technological Relatedness) and f[ are signif

• Journal of the East Asian Society of Dietary Life
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• v.4 no.2
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• pp.17-26
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• 1994

This study was an attempt to investigate various factions, such as the calorie, nutrient intake, physical activity, blood lipids, obesity prevalence and body fat distribution on NIDDM male diabetics. General characteristics, physical activity and exercise levels of subjects were invesigated by interviewing, daily calorie and nutrient intake were measured by convenient method. The following anthropometric measurements were made on all participats : weight, height. Also waist and hip circumference were measured on 174 male diabetics to get waist-to-hip circumference ratio as index of the body fat distribution. For measurement of plasma lipids, 12-hour fasting blood samples were drawn The results of this study were summarized as follows : 1. At the onset of diabetes, the major self-diagnosed symptoms were polydipsia, fatigue, and body weight redution 2. The average of daily energy intake of male diabetics was 2106 Kcal which is 96% of the RDA Percentage of energy is that carbohydrate:protein : pat=70:14:16. 3. Among the NIDDM male subjects, 59% was exercise regularly. 4. Obese subjects above in the ideal body weight of 120% are presently 17%, but 39% of subjects were reported to be obese in the past. The mean BMI of the male NIDDM diabetics is 23.3${\pm}$2.6 and the past mean BMI was 25.2${\pm}$2.7 The mean WHR was 0.93${\pm}$0.10. 5. When diabetics were divided into obese and nonobese group according to RBW, energy intake, blood pressure, blood glucose and total cholesterol were not significantly different between the two groups, but LDL and VLDL-cholesterol were significantly higher in the obese group. 6. RBW did not correlate with cholesterol and triglyceride, but WHR correlated significantly with cholesterol and triglyceride. In conclusion, these results from a present study support previous findings indicating that not only the degree of obesity but also the localization of fat is a risk factor for diabetes.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.12
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• pp.1937-1941
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• 2014

The effects of Tabebuia avellanedae (Taheebo) on exercise endurance capacity were investigated using mice in an adjustable-current water pool. Compared to the control group, a 1.8~2.0 fold increase in swimming time was observed in mice administered hot water extract (TAW) and 80% ethanol extract (TAE) of inner bark from T. avellanedae. Blood lactate level, an important fatigue relevance factor, was significantly lower in the TAW and TAE groups than in the control group. The total phenolic contents of TAW and TAE were $93.3{\pm}1.6$ and $115.7{\pm}1.5mgGAE/g$, respectively. The levels of flavonoids in the extracts were $77.3{\pm}1.3$ and $95.9{\pm}1.7mgCE/g$, respectively. Higher antioxidant activities of TAE were observed in each assay at the same concentration as compared to TAW. Correlation between antioxidant activities of TAE with total polyphenol contents was observed. These results suggest that extracts of Taheebo increase exercise endurance capacity by elevating antioxidative potentials.

• Journal of Digital Contents Society
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• v.18 no.5
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• pp.957-967
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• 2017

In this study, factor, is focused on user's psychology and SNS using style, of intention to use SNS continuously being affeted to who want to stop using SNS. This study utilized the foundational frame of PCM and TAM2 and indepednent variable and Mediating variable were based on previous research. I used statistical programs such as AMOS 18.0 and SPSS 18.0 to verify the practical examination of the hypothesis of this study and the questionnaire was distributed to the public and IT students who once used SNS, and made the 443 questionnaires to analyze on final except missing values and insincere responses. The result of study was that intention to use SNS continuously are affected by positive and negative psychological factors and will be helpful to provide a service plan for SNS and establish for marketing strategy.