• 가정과삶의질연구
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• 제13권4호
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• pp.101-114
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• 1995

The purpose of this study was to investigate the factors which influenced the quality of life of elderly women living alone or with the spouse. A survey using interview was administered to 221 elderly women living in Seoul and Pusan The major findings were as follows: 1) The family life satisfaction of elderly women was determined by the quality of relationship with her eldest son's wife shared activities financial strain and location. The determinants of consumer life satisfaction were financial strain materialism tenure and the number of income sources, Housing life satisfaction was influenced by the convenience of neighborhood facilities tenure and housing structure type. 2) The quality of relationship with her eldest son's wife social activities financial strain tenure and the reason for independent household formation explained the variance of the life satisfaction about 29% by using a stepwise multiple regression method.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1677-1682
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• 2015

Cancer progression is attained by uncontrolled cell division and metastasis. Increase in tumor size triggers different vascular channel formation to address cell nutritional demands. These channels are responsible for transferring of nutrients and gaseous to the cancer cells. Cancer vascularization is regulated by numerous factors including vascular endothelial growth factors (VEGFs). These factors play an important role during embryonic development. Members included in this group are VEGFA, VEGFB, VEGFC, PIGF and VEGFD which markedly influence cellular growth and apoptosis. Being freely diffusible these proteins act in both autocrine and paracrine fashions. In this review, genetic characterization these molecules and their putative role in cancer staging has been elaborated. Prognostic significance of these molecules along with different stages of cancer has also been summarized. Brief outline of ongoing efforts to target hot spot target sites against these VEGFs and their cognate limitations for therapeutic implications are also highlighted.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2009년도 추계학술발표대회 논문집
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• pp.95-99
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• 2009

To avoid monotony of functionalistic architecture that may be considered the mainstream of modernism architecture, in recent days, the modern architecture displays diversified characteristics. Geometric manipulation method that creates an open space having manipulated a basic geometric shape like hexahedron (cutting out or joining the spatial area onto one side of the figure) is the space manipulation technique that has been introduced and emerged on a full scale since 1970. This technique has been developed as a type of living quarters that has equipped with passive control function, making outside climate flow into the interior. Recently methods for diversified space creation by means of geometry manipulation have begun to appear in domestic low rise multi-family housings other than inflexible box type high-rise building constructions, which comprise the mainstream of multi-family housing.

• BMB Reports
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• 제49권8호
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• pp.424-430
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• 2016

Autophagy, an evolutionarily conserved cellular degradation pathway of the lysosome, is associated with many physiological and pathological processes. The hallmark of autophagy is the formation of the autophagosome that engulfs and degrades cytosolic components via its fusion with the lysosome, in either a selective or a non-selective manner. Autophagy is tightly regulated by proteins encoded by autophagy-related (atg) genes. Among these proteins, ATG8/LC3 is essential for autophagosome biogenesis/maturation and it also functions as an adaptor protein for selective autophagy. In mammalian cells, several homologs of yeast Atg8 such as MAP1LC3, GABARAP, and GABARAPL 1/2 have been identified. However, the biological relevance of this gene diversity in higher eukaryotes, and their specific roles, are largely unknown. In this review, we describe the mammalian ATG8/LC3 family and discuss recent advancements in understanding their roles in the autophagic process.

• Journal of Species Research
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• 제7권1호
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• pp.9-12
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• 2018

In 2016, as part of a larger effort to discover indigenous prokaryotic species in Korea, we isolated the family Deinococcaceae and Planctomycetaceae as unrecorded bacterial species. From the high 16S rRNA gene sequence similarity (>98.5%) and formation of a robust phylogenetic clade with known species, it was determined that each strain was a distinct bacterial species. There are no official reports that these two species have been described in Korea; therefore, the bacterial strains of Deinococcus and Blastopirellula are described for the first time in Korea. Gram reaction, colony and cell morphology, basic biochemical characteristics, and isolation sources are also described in the species description section.

• 한국산업정보학회논문지
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• 제16권4호
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• pp.119-125
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• 2011

The part family (PF) formation in a cellular manufacturing has been a key issue for the successful implementation of Group Technology (GT). Basically, a part has two different attributes; i.e., design and manufacturing. The respective similarity in both attributes is often conflicting each other. However, the two attributes should be taken into account appropriately in order for the PF to maximize the benefits of the GT implementation. This paper proposes a clustering algorithm which considers the two attributes simultaneously based on pareto optimal theory. The similarity in each attribute can be represented as two individual objective functions. Then, the resulting two objective functions are properly combined into a pareto fitness function which assigns a single fitness value to each solution based on the two objective functions. A GA is used to find the pareto optimal set of solutions based on the fitness function. A set of hypothetical parts are grouped using the proposed system. The results show that the proposed system is very promising in clustering with multiple objectives.

• Computers and Concrete
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• 제6권2호
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• pp.133-153
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• 2009

Discrete element modeling (DEM) in concrete technology is concerned with design and use of models that constitute a schematization of reality with operational potentials. This paper discusses the material science principles governing the design of DEM systems and evaluates the consequences for their operational potentials. It surveys the two families in physical discrete element modeling in concrete technology, only touching upon probabilistic DEM concepts as alternatives. Many common DEM systems are based on random sequential addition (RSA) procedures; their operational potentials are limited to low configuration-sensitivity features of material structure, underlying material performance characteristics of low structure-sensitivity. The second family of DEM systems employs concurrent algorithms, involving particle interaction mechanisms. Static and dynamic solutions are realized to solve particle overlap. This second family offers a far more realistic schematization of reality as to particle configuration. The operational potentials of this family involve valid approaches to structure-sensitive mechanical or durability properties. Illustrative 2D examples of fresh cement particle packing and pore formation during maturation are elaborated to demonstrate this. Mainstream fields of present day and expected application of DEM are sketched. Violation of the scientific knowledge of to day underlying these operational potentials will give rise to unreliable solutions.

• 한국식품조리과학회지
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• 제28권6호
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• pp.731-740
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• 2012

This study was made to the adult females over 20's in the family that prepared the ritual food personally or in the family that conducts ritual or did not do the ritual for the religious reasons. And based on the prepare method of the ritual food, ritual and recognition of ritual good. 245 responses which took up 80.86% had responded they do the ritual or semi-ritual and Buddhism was most prominent religion among them. The cost for ritual food also had statically significant differences by the age, marriage status and income and on the terms of the income, more the income was more they spend on the ritual food. The ritual utensil used for the ritual food also show significant differences by the age, marriage status, family make-up formation, religion. The form and meaning of the ritual have been changed as the society changes but is still important subject matter for most of homes. Responders were preparing the ritual with all the sincerity to their ancestors with practical and realistic decisions.

• 한국주거학회논문집
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• 제22권3호
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• pp.135-144
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• 2011

This study has extracted elements and related factors in the modernization of Hanok, using an evaluation method, and has also considered the possibilities of modern images using AHP analysis. As a result, first, the elements that form the urban landscape of historical and cultural environment have to be created by extracting elements from the subject standard for construction of the elements selected. As for the aspect of blending history, culture and environment, scenic and important architectural aspects were delineated. Second, based on selected components of the basic type of features and construction, roof types, vertical and horizontal elements were simulated after setting the criteria. Third, according to its historical cultural circumstances the man-made landscape and the traditional measure of the model, specific values of the elements for the formation of structures were evaluated by priority. A region characterized by old city houses constructed of objective elements can possibly be combined. In addition, a Hanok multi-family house fitted for modern life and a variety of models to develop and validate the possibility and utilization of this study can be expected.

• The Plant Pathology Journal
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• 제39권3호
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• pp.235-244
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• 2023

Acidovorax citrulli (Ac) is a phytopathogenic bacterium that causes bacterial fruit blotch (BFB) in cucurbit crops, including watermelon. However, there are no effective methods to control this disease. YggS family pyridoxal phosphate-dependent enzyme acts as a coenzyme in all transamination reactions, but its function in Ac is poorly understood. Therefore, this study uses proteomic and phenotypic analyses to characterize the functions. The Ac strain lacking the YggS family pyridoxal phosphate-dependent enzyme, AcΔyppAc(EV), virulence was wholly eradicated in geminated seed inoculation and leaf infiltration. AcΔyppAc(EV) propagation was inhibited when exposed to L-homoserine but not pyridoxine. Wild-type and mutant growth were comparable in the liquid media but not in the solid media in the minimal condition. The comparative proteomic analysis revealed that YppAc is primarily involved in cell motility and wall/membrane/envelop biogenesis. In addition, AcΔyppAc(EV) reduced biofilm formation and twitching halo production, indicating that YppAc is involved in various cellular mechanisms and possesses pleiotropic effects. Therefore, this identified protein is a potential target for developing an efficient anti-virulence reagent to control BFB.