• Clinical and Experimental Reproductive Medicine
• /
• 제21권2호
• /
• pp.221-226
• /
• 1994

Copper T 380A intrauterine devices were inserted to nine thousand and nine hundred twenty women by 51 KAVS-member physicians since January 1, 1993 through December 31, 1993. This study was undertaken for the clinical analysis on a total of 9,920 women wearing Copper T 380A to grasp the effectivness as well as the expulsion rate due to a various side effects. The following features were the results of the study: 1. During the twelve months period, from January 1993 to December 1993, the largest number of IUD insertion per one physician is 740 cases and the smallest number 60 cases, the mean 195 cases. 2. After insertion of Copper T 380A, a total of 117 cases were removed the IUD;81 cases(0.8%) were due to extensive bleeding and 36 cases(O.36%) were due to pain. The pregnancy failure rate represented comparatively lower rate, 0.08% (8 cases) and the expulsion rate was 0.06%(6 cases). 3. The removal rate of Copper T 380A was different by physicians. The highest removal rate for bleeding was 3.13% and 13 physicians(25.5%) did not experience any bleeding cases. 4. For the removal rate for pain, 30 physicians(58.8%) did not experience any removal of IUD due to pain while 21 physicians(41.2%) removed IUD due to pain: 17 physiciansC33.4 %) had 0.1-1.5% of removal rate and 4 physiciansC7.0%) had 1.6-2.1% of removal rate. 5. A total of 43 physicians(84.3 %) did not experience any pregnancy failure case while 8 (15.7%) physicians was experienced pregnancy failure rate. Four physicians(7.8%) had 0.1-0.5% of pregnancy failure rate and 4 physicians had 0.6-1.0% of pregnancy failure rate. 6. Expulsion rate showed comparatively lower, 0.06% in this study. A total of 45 physicians (88.2%) did not experience any expulsion cases while 6 physicians(11.7%) had expulsion rate with the highest expulsion rate of 2.0%.

• 한국임상수의학회지
• /
• 제29권3호
• /
• pp.203-206
• /
• 2012

심부전의 치료는 심방의 용적 과부하를 줄이기 위한 이뇨제, 심실 압력 과부하를 줄이기 위한 혈관확장제, 심근의 수축력을 향상시키기 위한 강심제 치료로 이루어진다. 이 중 이뇨제가 개의 심부전 조절에서 가장 중요하다. 하지만 장기간의 이뇨제 사용으로 급성 신부전이나 전해질 이상과 같은 부작용이 발생할 수 있다. 따라서 이 연구는 개에서 부작용이 적으면서 더 나은 이뇨효과를 가지는 생약성분의 이뇨제를 찾기 위해 설계되었다. 5마리의 건강한 개를 대상으로 한 예비실험에서 목통(Akebia quinata Decaisne) 추출물은 경도에서 중등도의 이뇨효과(furosemide 2 mg/kg 용량 효과의 0.3-0.5배의 효력)를 보였으며 혈청화학 수치와 전해질 변동은 거의 없었다. 실험 개체 수가 적고 기간이 충분하지 않지만 이 실험을 통해 심부전 환자에서 furosemide의 사용량을 줄이거나 대체할 수 있는 생약성분의 이뇨제 성분을 발굴하였다.

• 지식경영연구
• /
• 제16권1호
• /
• pp.71-93
• /
• 2015

With the rapid growth of the internet, electronic commerce has become accepted as one of the major purchasing channels for consumers. As more and more consumers search for and purchase products through the internet, intra-industry competition of electronic commerce has become fierce. Therefore, electronic commerce service providers pay attention to factors that prevent existing customers from leaving there services in the service failure situation. In this regard, electronic commerce service providers should make service recovery efforts for consumer recovery satisfaction after service failure. In this study, we suggest that procedural justice, interactional justice, distributive justice and authenticity have positive impacts on recovery satisfaction. In addition, we also propose that involvement plays moderating roles in the relationships between procedural justice, interactional justice, distributive justice, authenticity and recovery satisfaction. We collected empirical data for this study over a period of two weeks from subjects who had service failure recovery experiences through electronic commerce. A total of 224 complete and valid responses were obtained. We carried out data analysis using a two-step methodology with SPSS 20.0 and SmartPLS 2.0. The first step in the data analysis was to establish the internal consistency, convergent validity, discriminant validity of the constructs. In the second step, we examined the structural model. The empirical results support the proposed model and partly identify the moderating effect of involvement differences. The moderate effect results show that procedural justice, distributive justice and authenticity have different impacts on recovery satisfaction in two groups. Cognitive factor such as the procedural justice and distributive justice have stronger impacts on recovery satisfaction in the high-involvement goods than in the low-involvement goods, while emotional factor such as authenticity has a stronger impact on recovery satisfaction in the low-involvement goods than in the high-involvement goods. We expect that this result will provide researchers and managers who are interested in electronic commerce service failure recovery with useful theoretical and practical implications.

• 한국해안·해양공학회논문집
• /
• 제22권2호
• /
• pp.120-125
• /
• 2010

재현기간에 따른 설계파고 산정시 Gumbel 극치분포함수의 축척모수와 위치모수를 확률변수로 고려할 수 있는 Monte-Carlo 모의법을 제안하였다. 축척모수의 불확실성의 정도에 따라 설계파고의 불확실성의 정도가 결정되며 그 분포형태는 Gumbel 분포함수를 따른다. 또한 내용년수에 해당하는 최대 유의파고 분포특성을 이용하여 재현기간에 따른 설계파고를 산정하는 경우에 더 많은 불확실성이 포함된다. 한편 피복재의 파괴모드에 대한 신뢰성 해석을 수행하여 설계파고의 불확실성에 대한 영향을 검토하였다. 설계파고의 불확실성을 고려하는 방법에 따라 재현기간 50년 동안 5% 피해수준에 해당하는 파괴확률을 산정하여 비교하였다. 설계파고의 불확실성이 년 최대 유의파고자료의 불확실성과 같다고 가정하면 파괴확률이 넓은 범위에 걸쳐서 산정된다.

• Radiation Oncology Journal
• /
• 제11권1호
• /
• pp.83-90
• /
• 1993

During the period from January, 1975, to June, 1989, one hundred patients with histopathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatmemt results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement ($56{\%}$), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was $24{\%}$. Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were $38.4{\%}$. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following: local failure alone (30/55=$54.6{\%}$), systemic failure alone (9/55=$16.4{\%}$), both local and systemic failure (16/55=$29.0{\%}$). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.

• Radiation Oncology Journal
• /
• 제38권1호
• /
• pp.18-25
• /
• 2020

Purpose: This study was aim to evaluate the patterns of failure according to radiotherapy (RT) target volume for cervical lymph nodes in metastases of unknown primary origin in head and neck region (HNMUO). Materials and Methods: Sixty-two patients with HNMUO between 1998 and 2016 were retrospectively reviewed. We analyzed the clinical outcomes and primary site failure depending on the radiation target volume. The target volume was classified according to whether the potential head and neck mucosal sites were included and whether the neck node was treated involved side only or bilaterally. Results: Potential mucosal site RT (mucosal RT) was done to 23 patients and 39 patients did not receive mucosal RT. Mucosal RT showed no significant effect on overall survival (OS) and locoregional recurrence (LRR). The location of primary site failure encountered during follow-up period was found to be unpredictable and 75% of patients with recurrence received successful salvage therapies. No significant differences in OS and LRR were found between patients treated to unilateral (n = 35) and bilateral neck irradiation (n = 21). Treatment of both necks resulted in significantly higher mucositis. Conclusions: We found no advantages in OS and LRR of patients with HNMUO when mucosal sites and bilateral neck node were included in the radiation target volume.

• Journal of Yeungnam Medical Science
• /
• 제36권2호
• /
• pp.115-123
• /
• 2019

Background: This study aimed to assess the in-field lymph node (LN) failure rate according to LN size and to investigate effect of LN size on the survival outcome of patients with locally advanced cervical carcinoma treated with concurrent chemoradiotherapy (CCRT). Methods: A total of 310 patients with locally advanced cervical carcinoma treated with CCRT were enrolled in retrospective study. LN status was evaluated by magnetic resonance imaging. All patients received conventional external beam irradiation and high-dose rate brachytherapy, and concurrent cisplatin-based chemotherapy. In-field LN failure rate according to LN size was analyzed. Results: The median follow-up period was 83 months (range, 3-201 months). In-field LN failure rate in patients with pelvic LN size more than 10 mm was significantly higher than that in patients with pelvic LN size less than 10 mm (p<0.001). A similar finding was observed in the infield para-aortic LN (PALN) failure rate (p=0.024). The pelvic and PALN size (${\geq}10mm$) was a significant prognostic factor of overall-survival (OS) and disease-free survival rate in univariate and multivariate analyses. The OS rate was significantly different between groups according to LN size (<10 mm vs. ${\geq}10mm$). Conclusion: A LN of less than 10 mm in size in an imaging study is controlled by CCRT. On the other hand, in LN of more than 10 mm in size, the in-field LN failure rate increase and the prognosis deteriorate. Therefore, a more aggressive treatment strategy is needed.

• 한국산학기술학회논문지
• /
• 제19권12호
• /
• pp.110-117
• /
• 2018

최근 무기체계가 복잡화, 다기능화 됨에 따라 최종 사용자인 소요군의 무기체계 운용, 정비 난이도가 점점 높아지고 어려워지고 있다. 그러나 이와 반대로 운용, 정비를 수행하는 운용병, 정비병의 근무(복무)기간이 단축되면서 장비 운용, 정비에 대한 숙련도가 낮아지고 있으며. 이러한 장비의 복잡화, 다기능화는 사용자와 정비자의 오작동, 실수 등을 유발시키게 되고 이로 인한 무기체계의 신뢰성 저하는 가용도, 전투준비태세 및 고장수리에 따른 수명주기비용에 영향을 미치고 있다. 이에 따라 소요군에서 운용간 발생한 고장사례 분석을 통하여 시사점을 살펴보고 이를 개선하기 위한 설계측면, 종합군수지원(ILS) 측면의 개선방안을 제시한다. 분석된 무기체계는 현재 해군에서 운용 중인 무기체계로 야전 운용간 실제 발생한 고장사례 730건에 대하여 수집하여 분석하였으며 1차 적으로 고장원인별 분류된 결과를 2차로 사전예방 가능한 고장과 사전예방 불가능한 고장으로 분류하여 사전예방 가능한 고장이 어느 정도 차지하는지 정도와 이에 대한 시사점, 사전예방 가능한 고장별 고장 최소화를 위한 대책과 제안사항을 제시하였다.

• 한국전산구조공학회논문집
• /
• 제33권6호
• /
• pp.401-409
• /
• 2020

확률론적 지진취약도 평가는 구조물 혹은 기기의 손상확률을 각 취약도 변수별 조합을 통해 이루어진다. 지진취약도로부터 구해지는 2개 이상 기기의 동시손상확률 계산은 기존에는 각 기기의 손상확률을 독립으로 가정해 왔다. 하지만 기기별 손상확률에 상관성이 있으며, 이를 평가한 결과 상관성에 따라 동시손상확률이 변화할 수 있는 결과를 보였다. 이 지진상관성을 무시하면 비보수적인 결과가 나오고 따라서 이를 고려해서 계산되어야 한다. 이 연구에서는 지진상관계수를 해석적으로 평가하기 위해 몇 가지 확률 변수를 선정하여 각 변수별로 혹은 통합하여 평가하고 그 차이를 비교했다. 그리고 단순화된 모델과, 복잡한 모델에 대한 상관계수 차이도 비교하였다. 이들 방법에 따른 상관계수의 결과와 차이를 분석했다. 그 결과 각 변수별로 평가하는 것과 통합하여 평가할 때 변수별 영향의 차이에 따라 상관성이 변화함을 확인하였고, 모델이 단순할수록 상관성이 높아짐을 확인하였다.

• Korean Journal of Radiology
• /
• 제20권4호
• /
• pp.649-661
• /
• 2019

Objective: To systematically review the evaluation of the diagnostic accuracy of pre-treatment apparent diffusion coefficient (ADC) and change in ADC during the intra- or post-treatment period, for the prediction of locoregional failure in patients with head and neck squamous cell carcinoma (HNSCC). Materials and Methods: Ovid-MEDLINE and Embase databases were searched up to September 8, 2018, for studies on the use of diffusion-weighted magnetic resonance imaging for the prediction of locoregional treatment response in patients with HNSCC treated with chemoradiation or radiation therapy. Risk of bias was assessed by using the Quality Assessment Tool for Diagnostic Accuracy Studies-2. Results: Twelve studies were included in the systematic review, and diagnostic accuracy assessment was performed using seven studies. High pre-treatment ADC showed inconsistent results with the tendency for locoregional failure, whereas all studies evaluating changes in ADC showed consistent results of a lower rise in ADC in patients with locoregional failure compared to those with locoregional control. The sensitivities and specificities of pre-treatment ADC and change in ADC for predicting locoregional failure were relatively high (range: 50-100% and 79-96%, 75-100% and 69-95%, respectively). Meta-analytic pooling was not performed due to the apparent heterogeneity in these values. Conclusion: High pre-treatment ADC and low rise in early intra-treatment or post-treatment ADC with chemoradiation, could be indicators of locoregional failure in patients with HNSCC. However, as the studies are few, heterogeneous, and at high risk for bias, the sensitivity and specificity of these parameters for predicting the treatment response are yet to be determined.