• Korean Journal of Acupuncture
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• 제28권4호
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• pp.159-167
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• 2011

Objectives : This study was performed to find a desirable way for acupuncture treatment of Alzheimer Disease. Methods : The authors reviewed several literatures about 'Alzheimer Disease' and 'Dementia'. Based on the review, we interpreted the causes and symptoms on viewpoint of three yin and three yang, and also researched desirable way for acupuncture treatment of Alzheimer Disease. Results and Conclusions : The symptoms of Alzheimer Disease belong to the unbalance between reverting yin and lesser yang. The factors affecting attack rate of Alzheimer Disease are also related with the unbalance between reverting yin and lesser yang. It is necessary to inhibit the function of reverting yin and to activate the function of lesser yang for the acupuncture treatment of Alzheimer Disease.

• International Journal of Oral Biology
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• 제45권1호
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• pp.1-7
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• 2020

Oral lichen planus (OLP) is a chronic inflammatory disease observed in approximately 0.5-2.2% of the population, and it is recognized as a premalignant lesion that can progress into oral squamous cell carcinoma (OSCC). The rate of malignant transformation is approximately 1.09-2.3%, and the risk factors for malignant transformation are age, female, erosive type, and tongue site location. Malignant transformation of OLP is likely related to the low frequency of apoptotic phenomena. Therefore, apoptosis-related genetic factors, like p53, BCL-2, and BAX are reviewed. Increased p53 expression and altered expression of BCL-2 and BAX were observed in OLP patients, and the malignant transformation rate in these patients was relatively higher. The involvement of microRNA (miRNA) in the malignant transformation of OLP is also reviewed. Because autophagy is involved in cell survival and death through the regulation of various cellular processes, autophagy-related genetic factors may function as factors for malignant transformation. In OLP, decreased levels of ATG9B mRNA and a higher expression of IGF1 were observed, suggesting a reduction in cell death and autophagic response. Activated IGF1-PI3K/AKT/mTor cascade may play an important role in a signaling pathway related to the malignant transformation of OLP to OSCC. Recent research has shown that miRNAs, such as miR-199 and miR-122, activate the cascade, increasing the prosurvival and proproliferative signals.

• 수산해양교육연구
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• 제26권4호
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• pp.838-845
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• 2014

The objective of this study was to propose the priorities among the possible development strategies that can activate the industry while the market potential of cruise tourism industry has been increasing. To achieve the research aim, the A'WOT (SWOT-AHP) method was adopted in this study focusing on Jeju cruise industry. As a result of analysis, the strength factor (0.421) was the most important thing among the proposed factors. And, opportunity (0.348), weakness (0.135), and threat (0.096) factors were calculated in turn. Based on the A'WOT analysis, the most urgent thing among the strategy alternatives was 'Installation of dedicated department for Jeju cruise industry'. Accordingly, this result can be utilized as the fundamental data in order to make an optimal decision following by the environmental changes in Jeju cruise industry.

• KIEAE Journal
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• 제9권5호
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• pp.85-96
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• 2009

This study analyzed a characteristic by types of urban regeneration helping the establishment of urban identity under social condition change. It will be foundation of sustainable urban development with strategy that secures world-wide competitive power. For this, sample cases that established identity from urban regeneration were reviewed about the main subject and the supporting subject in business side and hardware, software, system, and finance in design factors. 4samples each in inheritance intensification type and change creation type were selected and analyzed. The result said it is most effective to establish urban identity when inheritance intensification type is the private-centered for urban regeneration. And it is better to do the project that the main subject and the supporting subject are taken by the private or the private-leading partnership. It is necessary to manage the region and plan events with software design factors more than hardware design factors. In addition, for urban identity, it was found to be desirable to utilize and preserve fully current resources such as historical scenery and activate the communities than making new facilities. On the contrary, the project based on change creation type needs to be under the public management with innovative idea. Also, when it comes to design factors, facilities related to culture and art and community spaces should open and run actively. It is important for the region to improve its image by New design style such as TOD. In software side, it is important to manage the region by monitoring about urban regeneration business and solve social mix and employment problem. On the other hand, in terms of system and administration, both types don't show a difference in urban identity establishment, since it is same that both should make partnership and get a support of subsidy to be most effective.

• 기술경영경제학회:학술대회논문집
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• 기술경영경제학회 2006년도 제28회 동계학술발표회 논문집
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• pp.226-247
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• 2006

Korea has accomplished remarkable economic growth based on the accumulating technological capability. Science and Technology policy aiming at quantitative growth has concentrated on S&T hardware infra-structure construction but it overemphasizes technological factors. This policy has not sufficiently reflected social and cultural elements that should be incorporated in S&T development process. Therefore many experts have been emphasizing the importance of science culture as an important ingredient of S&T policy. This paper aims at investigating how science culture could be diffused. Nowadays, many countries have a strong interest in science shop as an important instrument of science culture. Science shop, however, has been activated in European area so it is not familar to Korea. However there are already a few science shops in Korea. In this paper, we will investigate the Korea science shops. In particular, we will analyze the current status, organizational structure and problems of Korea science shops. we will draw some important policy implications to activate science shops and to strengthen S&T policies in Korea.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 추계학술대회논문집B
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• pp.715-719
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• 2000

It is reported that we are facing the serious environment pollution difficulties such as acid rain, green house effects, etc. The gaseous matter CO, NOx, SOx, VOCs which are regarded as main factors for these current pollutions are mainly emitted from power plants and vehicles. Therefore several leading countries are regulating the related laws strictly, especially exhaust emissions from a Diesel engine without an after treatment device. The Objective of this study is to find out NOx removal characteristics focused on emissions of a Diesel engine using radical at each engine speed and load. It is generated from outer air and put into a mixing chamber in the end of exhaust line. In addition, the optimum temperature condition to activate reaction by radical is experimentally carried out. Concentration of exhaust emissions is analyzed from the gas anlayzer(KaneMay) and FTIR to estimate by-products.

• Molecules and Cells
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• 제45권6호
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• pp.353-361
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• 2022

Chronic rhinosinusitis (CRS) is a multifactorial, heterogeneous disease characterized by persistent inflammation of the sinonasal mucosa and tissue remodeling, which can include basal/progenitor cell hyperplasia, goblet cell hyperplasia, squamous cell metaplasia, loss or dysfunction of ciliated cells, and increased matrix deposition. Repeated injuries can stimulate airway epithelial cells to produce inflammatory mediators that activate epithelial cells, immune cells, or the epithelial-mesenchymal trophic unit. This persistent inflammation can consequently induce aberrant tissue remodeling. However, the molecular mechanisms driving disease within the different molecular CRS subtypes remain inadequately characterized. Numerous secreted and cell surface proteins relevant to airway inflammation and remodeling are initially synthesized as inactive precursor proteins, including growth/differentiation factors and their associated receptors, enzymes, adhesion molecules, neuropeptides, and peptide hormones. Therefore, these precursor proteins require post-translational cleavage by proprotein convertases (PCs) to become fully functional. In this review, we summarize the roles of PCs in CRS-associated tissue remodeling and discuss the therapeutic potential of targeting PCs for CRS treatment.

• Journal of Korea Trade
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• 제27권3호
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• pp.87-102
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• 2023

Purpose - Although the importance and necessity of "sustainable supply chain management (SCM)" is emphasized, it is often not realized due to conflicting results, the long time required, and large-scale changes brought about by sustainability. This study used the innovation resistance model to confirm the influence of sustainable SCM innovation resistance factors and dynamic capabilities on adoption intentions. This approach made it possible to understand the factors that hinder adoption of sustainability practices and to identify the relationships among influencing factors. It should also help to establish effective policies or strategies. Design/methodology - Through a literature review, the characteristics of sustainable SCM were classified into relative advantage, compatibility, perceived risk, and complexity. The effects of these innovation characteristics on innovation resistance in sustainable SCM and the effects of innovation resistance on adoption intentions were confirmed. In addition, the effects of SCM capabilities on innovation resistance and adoption intentions were analyzed, and the mediating effect of innovation resistance was analyzed. Findings - Compatibility, perceived risk, and flexibility had significant effects on innovation resistance. In turn, innovation resistance had a significant effect on adoption intention, and flexibility had a significant effect on intention to adopt. A partial mediating effect of resistance to innovation was confirmed. Originality/value - Although many previous studies have acknowledged trade-offs with sustainability, most sustainable SCM studies dealt with the correlations among positive drivers of adoption, practices, and performance. This study confirmed the process of accepting sustainable SCM innovation in a single model and is expected to serve as a cornerstone for future sustainable SCM adoption studies. In addition, our findings should help establish effective policies or strategies to activate SSCM adoption by identifying the factors that hinder the adoption of sustainable SCM.

• 정보관리학회지
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• 제39권1호
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• pp.17-44
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• 2022

본 연구는 대학도서관 이용자의 도서관 불안 요인을 분석하여 비대면 서비스가 도서관 불안해소에 미치는 영향에 관한 방안 제시를 목적으로 하였다. 이를 위해 코로나19 사태에 따른 대학도서관의 이용자 서비스 대응 활동 사례를 살펴보고, 재학생 5,000명 이상 10,000명 이하의 국내 4년제 대학도서관에서 재학생 1인당 도서관 방문자수가 가장 높은 순위부터 40교를 선정하여 비대면 방식의 정보 서비스 및 프로그램 사례를 분석하였고, K대학도서관을 이용하는 재학생을 대상으로 K-LAS를 재구성하여 설문조사를 실시하였다. 수집된 데이터를 대상으로 빈도분석, 기술통계분석, 탐색적 요인분석, 신뢰도분석, 상관관계분석, 다중회귀분석을 적용하여 이용자의 도서관 불안 요인을 분석하였다. 도서관의 물리적·환경적 요인, 자료검색선정 요인, 디지털 정보시스템 요인, 사서(직원) 요인, 심리·정서적 요인등 5가지 도서관 불안 요인과 비대면 서비스 활성화 요인간 관계를 파악하고, 비대면 서비스 활성화 요인이 도서관 불안요인에 미치는 영향을 살펴보았으며, 그 결과, 비대면 서비스 활성화 요인들이 도서관 디지털 정보시스템 불안 요인에 가장 크게 영형을 끼치는 것으로 나타났다. 분석결과에 기초하여 비대면 서비스 활성화를 통하여 이용자의 도서관 불안해소 방안을 도출해보고자 하였다.

• 대한안전경영과학회지
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• 제12권1호
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• pp.83-96
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• 2010

Learning Organization is a learning based community to make the most important value in the era of Knowledge Economy, Creation. That's why people share, facilitate personal, individual's knowledge & experience systems each other and make good thoughts & ideas in the organization. This study measures the building practices having conducted the F team in Samsung electronics using DLOQ that indicates the activate degree of Learning Organization and the quantitative degrees of Learning Organization through comparing the cross-evaluation between the already measured companies in addition to analyzing the F team's success factors. Learning Organization requires sustainable and continuous activity, not completes by changing many factors with human resources. The study will have the achievement if we measure the successful activity through global companies built a Learning Organization and facilitate the improvement activity sustainably.