• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.9 no.1
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• pp.16-24
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• 1996

In order to satisfy the demand of good treatment of Oriental medicine, I investigated many books mentioned about Liver spot. The results were as follows: 1. They have called the Liver spot many other terms in the oriental medicine. 2.. The Liver spot is facial disease, so it is deeply related with yang-myong kyong(陽明經) 3. As the external cause of the Liver spot, wind and fire evil have been emphasized. 4. Intoxication of bud of banha(半夏) poison and alcohol absorption can be one of the causes. 5. As the internal cause of the Liver spot, each other vapour asthenia fever from constipation seven modes of emotion, asthenia of the spleen and stomach and insufficiency of kidney-yin(腎陰) 6. Nowadays, the deficiency of kidney-yang(腎陽) is also included as the cause of the Liver spot. 7. Many oriental doctors have talked about the relationship between the Liver spot and women, but I can't find any concrete talking about the relationship between menstration and the Liver spot, pregnancy and the Liver spot. 8. They have administrated many other herb medicines for the treatment the Liver spot.

• Journal of Sasang Constitutional Medicine
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• v.34 no.4
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• pp.49-56
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• 2022

Objectives The purpose of this study is to compare the changes before and after constitutional acupuncture treatment in soyangin who received embedding therapy for wrinkle improvement. Methods A retrospective study reviewing medical records was conducted. The patient was classified as a Soyangin by a specialist based on K-PRISM, personality, appearance, voice and usual symptoms. Records on the degree of wrinkles, postoperative symptoms, and patient satisfaction were reviewed. Results The patient's wrinkles were improved after the embedding therapy. After therapy symptoms were fever, flushing, and burning sensation. After acupuncture, these symptoms were reduced. Patient satisfaction increased after constitutional acupuncture treatment. Conclusion As a result of embedding treatment in Soyangin patients, there was an effect of wrinkle improvement. As a result of constitutional acupuncture treatment, anxiety and stress were reduced before the procedure, and symptoms of heat, burning, and flushing were reduced after the procedure.

• Pediatric Infection and Vaccine
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• v.22 no.3
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• pp.210-215
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• 2015

Macrophage activation syndrome (MAS) is a rare complication in systemic lupus erythematosus (SLE) that can be triggered by infections. Due to the fact that MAS may mimic clinical features of underlying rheumatic disease, or be confused with an infectious complication, its detection can prove challenging. This is particularly true when there is an unknown/undiagnosed disease; and could turn into an even greater challenge if MAS and SLE are combined with a viral infection. A-14-year-old female came to the hospital with an ongoing fever for 2 weeks and a painful facial skin rash. Hepatomegaly, pancytopenia, increased aspartate aminotransferase, elevated serum ferritin and lactate dehydrogenase were reported. No hemophagocytic infiltration of bone marrow was reported. The patient was suspected for hemophagocytic lymphohistiocytosis. Her skin rashes were eczema herpeticum, which is usually associated with immune compromised conditions. With the history of oral ulcers and malar rash, positive ANA and low C3, C4 and the evidence of hemolytic anemia, she was diagnosed as SLE. According to the diagnostic guideline for MAS in SLE, she was diagnosed MAS as well, activated by acute HSV infection. After administering steroids and antiviral agent, the fever and skin rash disappeared, and the abnormal laboratory findings normalized. Therefore, we are reporting a rare case of MAS triggered by acute HSV infection as the first manifestation of SLE.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.4
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• pp.381-388
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• 2019

Recently, the importance of individual skin characteristic is emphasized for customized beauty products. There are many studies on the concept of the syndrome differentiation, related to individual cosmetics in Korean Medicine. However, skin characteristic according to Yin deficiency syndrome (YDS), which is associated with aging, are yet to be clarified. The objective of this study was to evaluate the skin characteristic and questionnaire of female with YDS compare to with non-YDS. 218 healthy females between 40 and 59 years of age were assessed for the skin hydration, elasticity, brightness (L^* value), redness (a^* value), pore, pigmentation, wrinkle, and sebum by Corneometerr^®, Cutometerr^®, and Janus lll. Independent t-test showed lower hydration, lower elasticity, and higher redness in the YDS group compared to the non-YDS group (all p < 0.05). There was significant difference on the facial fever, insomnia, decreased amount of urine, and skin sensitive checklist. These results suggested that using the questionnaire associated with YDS and skin characteristic could separate skin types and apply to customized beauty products.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.73-81
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• 2010

Objectives : The purpose of this study is to establish literatural evidence about thermotherapy and cryotherapy for Korean medicine through literatural review. Methods : Applicable paragraphs which were related to the thermotherapy and cryotherapy of cutaneous and muscle meridian were phrased from in "Yibujicheng(醫部集成) and "Dongyibaojian(東醫寶鑑)" where were archiving of Oriental or Korean medicine literatures. Searched paragraphs were analysed for establishing historical and theoretical bases of thermotherapy and cryotherapy in Korean medicine. Results : Thermotherapy of cutaneous and muscle meridian(經皮經筋溫熱療法) such as hot pack, warm water therapy, paraffin bath, ultrasound is originated from yu(慰) warm water(溫水) hot water(熱水). Matching indications are various pain conditions(caused by coldness(寒), hard-work(僗若), extravasated blood(瘀血), inflammatory skin disease, frostbite and several internal diseases. It also treats gynecological diseases and facial palsy. Diathermic therapy on acupuncture points(穴位照射溫熱療法) such as infra-red, microwave, shortwave is originated from huolu(火爐), wenlu(溫爐), xianglu(香爐), lamp light(燈火). Its objective is to improve the effects of herb medicine by aiding sweating or to treat the residual symptoms of fever disease or to care skin disease and pain from bone fracture, contusion. Cryotherapy of cutaneous and muscle meridian(經皮經筋溫寒冷療法) such as ice pack, ice spray, iced whirpool, cool water bath is originated from lengfu(冷敷), lengtie(冷貼), lengshiyu(冷石熨). Matching indications are contusions, animal bite injury, corn(肉刺) and (淋病), eye disease, nasal bleeding, hemorrhoid, inflammatory skin disease and chicken pox. Conclusions : Thermotherapy and cryotherapy of cutaneous and muscle meridian(經皮經筋溫冷療法) are the treatments which were used in Korean medicine from the ancient Korean medicine. As scientific equipments were originated from yu(慰), huolu(火爐), wenlu(溫爐), xianglu(香爐), lamp light(燈火). lengfu(冷敷), lengtie(冷貼), lengshiyu(冷石熨). It can be said that these are elements of Korean medicine. More rigorous studies are needed to establish clinical evidence about not only thermotherapy and cryotherapy but also the other physiotherapy of Korean medicine.

• Journal of Acupuncture Research
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• v.19 no.3
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• pp.88-94
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• 2002

Objective : This study was done to observe the effects on the themal changes of Hominis Placenta acupuncture therapy. The objectives are as follows; If there are remarkable local thermal changes between pre- and post- Hominis Placenta acupuncture therapy on D.I.T.I. or not. If there are those, we examine how long its changes are maintained, the adequate interval and clinical applications of therapy. Methods : To study the local thermal changes in therapy, D.I.T.I. was used. Thermal temperatures were measured pre- and post-therapy (1 hour, 1st day, 2nd day, and 7th day). The study group was divided into two groups. One was HP(Hominis Placenta) group(N=20), the other was NS(Normal Saline) group. The Hominis Placenta acupuncture was injected into 4 points (Fengmen(風門: $B_{12}$), Feishu(肺兪: $B_{13}$), Fufen(附分: $B_{41}$), Pohu(魄戶: $B_{42}$)) by 0.05ml. Results : The following results were obtained. 1. PLACENTA HOMINIS is the dried placenta of a healthy woman, used to warm the kidney for impotence, infertility, lack of lactation, and replenish Gi(氣), blood, vital essence for emaciation, hectic fever, night sweating in consumptive diseases. 2. Hominis Placenta acupuncture therapy has effects on invigoration of vital energy (補氣, 益氣), nourishing blood (養血), and tonifying the essence (補精). 3. Hominis Placenta acupuncture therapy is effective at tissue regeneration, antibody formation, increasing immunity, hormone-like effects. So, it is clinically used in osteoporosis and facial nerve paralysis. 4. There was no significant dermatothermal changes at NS group, but HP group had remarkable changes between operated and non-operated area in post-therapy 1hour. But there were not any change on 1, 2, and 7th day.

• Journal of Pharmacopuncture
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• v.2 no.1 s.2
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• pp.73-91
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• 1999

This study was carried out to invastigate the researches of Snake Venom and snakes which used in treatment 1. The fist literature that used the snake for treatment is Shin Nong Ben Cao Jing 2. Composition of Snake Venom is consist of Enzymatic proteins ; Phospholipase A(A1-2), Protease, L-amino acid oxidase etc, and Non-enzymatic proteins ; Crotamine(Cytolysin), Proteolytic factor(Hematoxin), Crotoxin(Neurotoxin) etc. 3. Main toxins in Snake Venom are Hematoxin, Cytolysin, Neurotoxin and Cardiotoxin. Lethal dose 50 value of Agkistrodon brevicaudus is $45.87{\mu}g$/18g, Agkistrodon saxatilis is $10.28{\mu}g$/18g, Agkistrodon ussuriensis is $8.68{\mu}g$/18g, therefore Agkistrodon ussuriensis has strongist Snake Venom of all in Korea. 4. Pharmacological actions of Snake Venom are anticoagulation, thrombolytic function, hypotensor etc. 5. Systemic syndromes and signs after snakebite are Dizziness(25.7%), Vomitting(23.1%), Fever(22%), Visual disturbance(18%), Headache(17.7%) and Dyspnea(17.6%), etc. 6. Local syndrome and sign after snakebite is Discoloration(54.2%), Bleeding(20.2%), Bullae(10.7%), Skinulcer(10.8%), etc. 7. Pathological syndromes after snakebite are WBC increase, Urine protein, Urine sugar, Haematuria and elevation of S-GDT, S-GPT etc. These syndromes are leaded by Hematoxin and Cytolysin. 8. Complication signs after snakebite are Cellulitis, Gastritis, Lympoma, Abscess etc. 9. Common function of Viperidae(Agkistrodon acutus or Zaocys dhumnades etc) is expelling the wind(祛風), removing obstruction in the channels(通絡), antipastic function(止痙). And it is used in order to cure hemiparesis, hemiplegia, facial palsy and CVA disease, etc. 10. Using way of snake for medical treatment is various like Herbal alchol therapy, pill, powder and injection etc. The Study on the Snake Venom should be carried out continuously for using of medical treatment.

• Childhood Kidney Diseases
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• v.8 no.2
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• pp.239-243
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• 2004

Acute poststreptococcal glomerulonephritis(APSGN) is the most common form of postinfectious glomerulonephritis, and acute pyelonephritis(APN) is the most severe form of urinary tract infection in childhood. However, the concurrence of two diseases is uncommon in the literature. We describe a case of APSGN accompanied with APN in a 5-year-old female who presented with fever, left flank pain, headache and facial edema. Urinalysis showed pyuria, microscopic hematuria, and mild proteinulra. Serial urine cultures grew Escherichia coli. ${^99m}$Tc-DMSA renal scan revealed a cortical defect in the upper pole of left kidney. She had a history of preceding pharyngitis, in addition, showed high blood pressure, high anti-streptolysin 0 titer, and low serum complement levels. The patient improved completely with supportive treatment, Including antibiotic and antihypertensive therapy. These findings suggested that APSGN and APN could be manifested simultaneously or be .superimposed on each other.

• Herbal Formula Science
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• v.23 no.1
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• pp.25-53
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• 2015

This report describes 90 prescriptions related to the use of Ostericum Radix(OR) blended as the main ingredient in the Dongeuibogam.

The following conclusions were reached through investigations on the prescriptions that use OR as a key component.

Prescriptions where OR was used as one of the monarch(drug) utilized for 27 therapeutic purposes in total.

It was searched that the frequency of prescriptions in the therapeutic purposes were as follows. The chapter of eyes is 22.2%, the wind is 13.4%, the child 11.1%, the cold is 8.9%, the head is 6.7%, the malaria disease 4.5% in the order.

Prescriptions that utilized OR as the main ingredient were most used for treating diplopia, facial nerve palsy, headache and a fever in the whole body. These were also used for treating 55 different types of diseases.

The dosage of OR in formulas was ranging from 2pun(about 0.75g) to 2don(about 7.5g). However, 1don(about 3.75g) was most used for clinical application.

We can find out that according to herbs or prescriptions blended with itself, OR made a variety of functions to eliminate cold with wind, humidity, pain, and convulsions from the body. And also, Bangpungtang was the most useful base prescription which used OR as the main component.

• Archives of Plastic Surgery
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• v.38 no.1
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• pp.77-80
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• 2011

Purpose: We report a patient with DiGeorge syndrome who was later diagnosed as mild metopic synostosis and received anterior 2/3 calvarial remodeling. Methods: A 16-month-old boy, who underwent palatoplasty for cleft palate at Chungnam National University Hospital when he was 12 months old of age, visited St. Mary's Hospital for known DiGeorge syndrome with craniosynostosis. He had growth retardation and was also diagnosed with hydronephrosis and thymic agenesis. His chromosomal study showed microdeletion of 22q11.2. On physical examination, there were parieto-occipital protrusion and bifrontotemporal narrowing. The facial bone computed tomography showed premature closure of metopic suture, orbital harlequin sign and decreased anterior cranial volume. The interorbital distance was decreased (17 mm) and the cephalic index was 93%. Results: After the correction of metopic synostosis by anterior 2/3 calvarial remodeling, the anterior cranial volume expanded with increased interorbital distance and decreased cephalic index. Fever and pancytopenia were noted at 1 month after the operation, and he was diagnosed as hemophagocytic lymphohistiocytosis by bone marrow study. He however, recovered after pediatric treatment. There was no other complication during the 12 month follow up period. Conclusion: This case presents with a rare combination of DiGeorge syndrome and metopic synostosis. When a child is diagnosed with DiGeorge syndrome soon after the birth, clinicians should keep in mind the possibility of an accompanying craniosynostosis. Other possible comorbidities should also be evaluated before the correction of craniosynostosis in patients as DiGeorge syndrome. In addition, postoperative management requires a thorough follow up by a multidisciplinary team of plastic surgeons, neurosurgeons, ophthalmologists and pediatricians.