• Journal of the Korean Society of Food Science and Nutrition
• /
• v.46 no.1
• /
• pp.34-38
• /
• 2017

Myelophycus simplex Papenfuss, a type of brown algae, is known to be majorly distributed in along the southern coast of Korea and Japan. The purpose of this study was to investigate the effects of M. simplex Papenfuss methanol extract (MSPME) on melanogenesis in ${\alpha}$-melanocyte-stimulating hormone-stimulated B16F10 melanoma cells. Melanin contents of B16F10 melanoma cells were decreased by 27, 41, and 59% in a dose-dependent manner, upon MSPME treatment at 100, 300, and $500{\mu}g/mL$, respectively. Tyrosinase activities in B16F10 melanoma cells were decreased by 18, 49, and 61% in a dose-dependent manner, upon MSPME treatment at 100, 300, and $500{\mu}g/mL$, respectively. MSPME suppressed expression of tyrosinase, tyrosinase-related protein-1, tyrosinase-related protein-2, and melanocyte-inducing transcription factor in B16F10 melanoma cells. Concentration of $50{\mu}g/mL$ of MSPME especially induced greater decreases in tyrosinase activity, melanin contents, and melanogenic enzyme protein expressions. This results indicate that MSPME inhibits melanin synthesis and tyrosinase activity, and M. simplex Papenfuss extract may be an ideal candidate as a skin whitening agent.

• Journal of Korean Academy of Nursing
• /
• v.4 no.1
• /
• pp.121-134
• /
• 1974

This study is an attempt to evaluate the use of an oral contraceptive by: 1. Deforming the acceptance rate of the oral contraceptive according to socio-demographic characteristics 5. Estimating the duration of the use of the contraceptive f. Discovering reasons why the contraceptive was discontinued 4. Computing the cumulative continuation and discontinuation rate according to socio-demographic characteristics, history of pregnancies, and attitude of husband at the time of selection of the contraceptive. One hundred sixty-eight women of child bearing age (14-49 years), residing in Yonhee Dong, Seoul, Korea and registered as oral contraceptive accepters at Yonsei Community Health Center, were interviewed during a three week period in 1973. The questionnaire was designed to determine the socio-demographic characteristics of the oral contraceptive accepters, the current status of their family planning practice, medical reactions if any, discontinuation practice, and the duration of the use of the contraceptive. The major findings of the study were as follows; 1. The acceptance rate was highest for women between 30 and 34 years of age, the mean age being 34.4 years. 2. Fifty six point five percent of all respondents said that thirty years of age was the ideal age to stop having children. 3. The average number of living children was 3.5 and fifty four point eight percent of respondents felt 2 boys and I girl was the ideal number of children. 4. The average number of pregnancies was 5.2 and the average number of induced abortion was I. 4. 5. Fifty eight point eight percent of the respondents had experience in the use of contraceptive methods in the past. 6. Forty one point seven percent of the respondents replied that they chose the oral contraceptive because, "it was not complicated to use." 7. Sixty four point eight percent of the women said their husband approved of their taking the pill. 8. The cumulative discontinuation rate was sixty point five percent of the total respondents for one year in first segment. 9. Sixty six point nine percent of the respondents had experienced side-effect while using the pill. The side effects for 68.9 percent of these women were castro-intestinal upsets. Twenty point eight percent of the women who had side effects consulted with medical personnel about them. Women who had more education had more side effects. 10. Seventy three point two percent of the women who discontinued the pill did so because of medical reasons. Women who were younger discontinued the pill for personal reasons more-often than older women. Among personal reasons listed for discontinuing the pill was the attitude of the husband. 11. The average duration of continuance of the contraceptive was 5.3 cycles under 29 years of age; 7.4 cycles between 30 and 34 years of age; and 8.4 cycles over 40 years of age. 12. The discontinuation rate was seem to increase sharply in the early cycle and increase more slowly in later cycle. Conclusions and suggestions: Since the attitude of the husband was shown to be important, the current family planning program should be expended to include approach to husband. For women who must use the oral contraceptive, education and support must be enhanced so that the discontinuation rate due to side effects will be decreased.

• Journal of Korean Philosophical Society
• /
• v.130
• /
• pp.187-218
• /
• 2014

Nietzsche stellt in seiner Philosophie den "${\ddot{U}}bermensch$" als existenziales Ideal des Menschen sowie als Menschentyp der Zukunft und "die ${\ddot{u}}bermenschliche$ Zukunft" als Zukunft des gesunden Menschen vor. Der ${\ddot{U}}bermensch$ und die ${\ddot{u}}bermenschliche$ Zukunft beinhalten in Nietzsches Philosophie den Sinn des gesunden Menschen und seiner gesunden Zukunft. Nach Nietzsche kann dieses gesunde Ideal durch die aktive Praxis des Menschen endlich verwirklicht werden. Nietzsche unterscheidet das aktive und das passive Verhalten des Menschen und leitet daraus die zwei $gegens{\ddot{a}}tzlichen$ Menschentypen her, also den aktiven Menschen (Herr der Moral des Lebens - geistig Starker) und den passiven Menschen (Sklave der Moral des Lebens - geistig Schwacher). Aber die Typologie dieser anthropologischen Differenz zielt nicht auf die Dualisierung der absoluten Differenz, sondern auf seine relativistisch-relationale ${\ddot{U}}berwindung$. Auf diese Weise setzt die philosophische Anthropologie Nietzsches im Grunde seine eigene praktische Philosophie voraus. Ferner bestimmt Nietzsche den Menschen als Zwischenwesen, das $hei{\ss}t$, dass der Mensch in Also sprach Zarathustra an der existenzialen Grenze zwischen Tier und ${\ddot{U}}bermensch$ und in seiner anthropologischen ${\ddot{A}}sthetik$ an der ${\ddot{a}}sthetischen$ Grenze zwischen $Versch{\ddot{o}}nerung$ und $Verh{\ddot{a}}sslichung$ des Lebens steht, sowie als $M{\ddot{o}}glichkeitswesen$, das an dieser Grenze durch die existenziale $Selbst{\ddot{u}}berwindung$ und die ${\ddot{a}}sthetische$ Selbstgestaltung in jedem Moment seine $Ver{\ddot{a}}nderungsm{\ddot{o}}glichkeit$ $sch{\ddot{o}}pferisch$ verwirklichen kann. Das Ziel dieser Arbeit ist es, aufgrund Nietzsches anthropologischen $Verst{\ddot{a}}ndnisses$ die anthropologische Methodologie zu $er{\ddot{o}}rtern$, die er $f{\ddot{u}}r$ die Verwirklichung der immanenten $Ver{\ddot{a}}nderungsm{\ddot{o}}glichkeit$ des Menschen in seiner Philosophie vorstellt.

• Journal of the Korean Society of Radiology
• /
• v.13 no.2
• /
• pp.261-270
• /
• 2019

The separation permeation characteristics of $N_2-O_2$ gas in air at cell membrane model of skin which irradiated by high energy electron(linac 6 MeV) were investigated. The cell membrane model of skin used in this experiment was a sulfonated polydimethyl siloxane(PDMS) non-porous membrane. The pressure range of $N_2$ and $O_2$ gas were appeared from $1kg_f/cm^2$ to $6kg_f/cm^2$. In this experiment(temperature $36.5^{\circ}C$), the permeation change of $N_2$ and $O_2$ gas in non-porous membrane by non-irradiation were found to be $1.19{\times}10^{-4}-2.43{\times}10^{-4}$, $1.72{\times}10^{-4}-2.6{\times}10^{-4}cm^3(STP)/cm^2{\cdot}sec{\cdot}cmHg$, respectively. That of $N_2$ and $O_2$ gas in non-porous membrane by irradiation were found to be $0.19{\times}10^{-4}-0.56{\times}10^{-4}$, $0.41{\times}10^{-4}-0.76{\times}10^{-4}cm^3(STP)/cm^2{\cdot}sec{\cdot}cmHg$, respectively. The irradiated membrane was significantly decreased about 4-10 times than membrane which was not irradiated. And ideal separation factor of $N_2$ and $O_2$ gas by non-irradiation was found to be from 1.32 to 0.42 and that of $N_2$ and $O_2$ gas by irradiation was found to be from 0.237 to 0.125. The irradiated membrane was significantly decreased about 4-5 times than membrane which was not irradiated. When the operation change(cut) and pressure ratio(Pr) by non-irradiation were about 0, One was increased to the oxygen enrichment and the other was decreased to the oxygen enrichment. The irradiated membrane was significantly decreased about 4-19 times than membrane which was not irradiated. As the pressure of $N_2$ and $O_2$ gas was increased, the selectivity was decreased. As separation permeation characteristics of $N_2-O_2$ gas in cell membrane model of skin were abnormal, cell damages were appeared at cell.

• The Korean Journal of Rehabilitation Nursing
• /
• v.3 no.1
• /
• pp.27-42
• /
• 2000

The purpose of this study was to identify the degree of sexual adjustment and quality of life in married men with spinal cord injuries and to furnish primary data to sexuality rehabilitation nursing practice which can lead to ideal sexual life and quality of life those men with SCI. Seventy married men with SCI were conveniently sampled in Kwangju, Suncheon, Mokpo and Seoul for responding the questionnaire, which was based on this research. With the research scale, SIS (Sexual interest and satisfaction) by Siosteen et al.(1990) and SB(Sexual behaviour) by Kreuter et al.(1996) were used for the measurement of sexual adjustment. And, for measuring quality of life was used SCI QL-23(Spinal cord injury of life-23) scale by Lundqvist et al.(1997). Data were collected from January 20 to March 20, 1999, using a structured questionnaire. A hundred volumes of questionnaire were used. and 85 volumes were collected, 70 volumes were used as research data after excluding 15 volumes unsuitable to data analysis. The obtain data were analysed using percentage, t-test, ANOVA, Duncan test, and Pearson's correlation by SAS PC+ program. The results were as follows: 1. The mean score of sexual interest and satisfaction of the subjects was 8.42. out of 18. The ways of their sexual behavior after spinal cord injuries were embracing and caressing (62.9%), kissing(58.6%), caressing breast with hands (55.7%), caressing breast with hands (52.9%), caressing genitals with hands (37.2%), caressing genitals with mouth(30.0%) and sexual intercourse (18.6%). The mean score of quality of life was 52.53 out of 100. 2. Age(F=3.24, p=.045) and caregiver (F=4.02, p=.022)were major variables which reveals significant differences in terms for sexual interest and satisfaction. The later results on Duncan's test showed that subjects who were in their 30s or 40s were significant higher than subjects whose age were in their 50s in their sexual interest and satisfaction. Also subjects with their spouse's care or mother's care were higher than those with other's care. 3. Subjects with incomplete paraplegia were higher than those with the complete paraplegia in sexual interest and satisfaction (F=3.01, p=.036). 4. Variables that showed the significant differences in the quality of life were education(t=2.860, p=.007) and period of marriage(t=2.125, p=.037). and occupational status(t=-2.161, p=.034). High school graduates, those who married before spinal cord injuries and those who didn't have occupation were higher than the other subjects. 5. Variables that revealed significant differences in the quality of life were time passage after spinal cord injuries(F=8.72, p=.001) and injured level of spinal cord(F=3.32, p=.042). Duncan's test showed that subjects who had lived for less than 4 years were higher those with time passage of 5-9 years and 10 years. Also subjects with lumbar injuries were higher than those with thoracic injuries in terms of quality of life. 6. There was negatively correlated between sexual interest and satisfaction and quality of life(r=-.256, p<.05). As a result of these findings sexuality rehabilitation for individuals with SCI was very important issue for their quality of life. Thus, registered nurses who care clients with SCI should activily participate in the client's sexual needs. Also, various sexual behaviors as well as sexual intercourse should be encouraged for the sexual adjustment of client's with SCI.

• Journal of Families and Better Life
• /
• v.23 no.2 s.74
• /
• pp.149-157
• /
• 2005

The purpose of this study was to identify current housing status and housing awareness such as housing values, satisfaction, and preferences among households with one child. Data were obtained from a questionnaire completed by both husbands and wives living in metropolitan area and aged between 25 and 45. Selected variables were the age, education level, and employment status of housewives, ideal number of children, monthly income, plan to give birth, and so on. Using purposive sampling method, five hundred questionnaires were administered and 360 questionnaires were analyzed. In accordance with the questions related to housing values, housing satisfaction of respondents was examined. In order to compare the housing values, preferences, and satisfaction among diverse variables of respondents, mean, t-test, F test, Duncan's multiple range test, $x^2$ test, and factor analysis were used. The major findings of this study are as follows: First, there were significant differences in current housing type, tenure type, and floor area according to housewives' age, education level, monthly income, and plan to give birth. Interestingly, households not having a plan to give birth in the future were living in larger house than the households having a plan to give birth. Second, housing values of households with one child were divided into 4 factors-environmental comfort, economy and convenience, social status symbolism, and adequacy of space planning. Items related to privacy showed the biggest difference between housing values and housing satisfaction. Third, most of the respondents wanted larger house than current housing. However, the need for quality of housing including floor area and amenities was significantly higher among households not having a plan to give another birth than households having a plan to give birth in the future.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.8 no.2
• /
• pp.143-149
• /
• 2008

A novel compact model for a five-port transformer balun is proposed for the efficient circuit design of hybrid balun. Compared to the conventional model, the proposed model provides much faster computation time and more reasonable values for the extracted parameters. The hybrid balun, realized in $0.18\;{\mu}m$ CMOS, achieves 2.8 dB higher gain and 1.9 dB lower noise figure than its passive counterpart only at a current consumption of 0.67 mA from 1.2 V supply. By employing the hybrid balun, a differential zero-IF receiver is designed in $0.18\;{\mu}m$ CMOS for IEEE 802.15.4 ZigBee applications. It is composed of a differential cascode LNA, passive mixers, and active RC filters. Comparative investigations on the three receiver designs, each employing the hybrid balun, a simple transformer balun, and an ideal balun, clearly demonstrate the advantages of the hybrid balun in fully differential CMOS RF receivers. The simulated results of the receiver with the hybrid balun show 33 dB of conversion gain, 4.2 dB of noise figure with 20 kHz of 1/f noise corner frequency, and -17.5 dBm of IIP3 at a current consumption of 5 mA from 1.8 V supply.

• Korean Journal of Human Ecology
• /
• v.12 no.4
• /
• pp.463-495
• /
• 2003

The purpose of this study was to obtain a fundamental data for developing a policy concerning women and child rearing and a parent education program for young parents who are around their childbirth, a period crucially important both for the parents in terms of the role adjustment, career management, and family finance, and for the infants in terms of its physical and psychological well-being. The subjects were 509 mothers before and after childbirth currently living in the Metropolitan City of Daejeon. Data were obtained through questionnaires and interviews in two major areas of pregnancy-delivery-childcare and parent education. Data were analyzed using SAS, mostly through frequency analysis, percentiles, t-tests, and F-tests. Results of descriptive analyses were organized along the following areas and issues: Pregnancy(family planning, regular check-ups, difficulties, prenatal education, costs, etc.); delivery(type of delivery, delivery related experience, costs, clinic/medical institute of choice, worries/problems, help/supports, etc.); postpartum care(place, kinds of help and helper, costs, postpartum care facilities, etc.); childcare circumstances(place, carer, time schedules, childcare centers or facilities feeding and weaning, etc.); husband's attitudes and involvement in the overall process; working mothers(maternity leave, temporary retirement for child rearing, etc.); and, parent education(family planning, pregnancy, delivery, postpartum care, child rearing, areas or issues needing parent education, facilitative and hindering factors to ideal parenting, etc.). Differences between groups of pregnant mothers and postpartum mothers, working- and non-working mothers, groups of different income levels, mothers and fathers of different educational levels, mothers of first pregnancy(or childbirth) and experienced mothers were also analyzed. Several conclusions with suggestions were drawn in relation to the need for strong implementation as well as developing of policies on women and childcare and for developing a new parent education program for parents before and after childbirth.

• Journal of the Korean Chemical Society
• /
• v.34 no.2
• /
• pp.130-135
• /
• 1990

The title compound (C13H17NO2S) is monoclinic, space group P21/a, with a = 13.756 (3), b = 9.310(4), c = 21.305(3) $\AA$, $\beta$ = 95.0。, Z = 8, V = 2718.11 $\AA$3, Dc = 1.23$g·{\cdot}cm-3$, (Mo k$\alpha$) = 0.71069$\AA$,$\mu$ = 2.18 cm-1, F(000) = 1071.86, T = 298, R = 0.085 for 2935 unique observed reflections with I >2.0$\sigma$(I). The structure was solved by direct methods. The C-H bond lengths and the methyl groups are fixed and refined as their ideal geometry by allowing to ride on the parent atoms. Both molecules A and B have almost same structures except for two terminal ethyl groups. The ethylene-like skeleton including the nitro group in one molecule is nearly perpendicular to the plane of the methylbenzene group and two ethyl groups form a cis-type structure which has the dfferent orientations between two molecules; in the molecule A, two terminal methyl groups being the opposite directional arrangement against the plane of its skeleton, while in the B, with the same directional structure from its plane. The molecules in the crystal are packed together by non-bonded van der Waals forces.

• Journal of the Korean Society for Precision Engineering
• /
• v.24 no.4 s.193
• /
• pp.138-146
• /
• 2007

Some biodegradable polymers and other materials such as hydrogels have shown the promising potential for surgical applications. Post surgical adhesion caused by the natural consequence of surgical wound healing results in repeated surgery and harmful effects. Recently, scientists have developed absorbable anti-adhesion barriers that can protect a tissue from adhesion in case they are in use; however, they are dissolved when no longer needed. Although these approaches have been attempted to fulfill the criteria for adhesion prevention, none can perfectly prevent adhesions in all situations. Overall, we developed a new method to fabricate an anti-adhesion membrane using biodegradable polymer and hydrogel. It employed a highly accurate three-dimensional positioning system with pressure-controlled syringe to deposit biopolymer solution. The pressure-activated microsyringe was equipped with fine-bore nozzles of various inner-diameters. This process allowed that inner and outer shapes could be controlled arbitrarily when it was applied to a surgical region with arbitrary shapes. In order to fulfill the properties of the ideal barriers f3r preventing postoperative adhesion, we adopted the pre-mentioned method combined with surface modification with the hydrogel coating by which anti-adhesion property was improved.