• 한국융합학회논문지
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• 제9권1호
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• pp.241-251
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• 2018

본 연구는 지역사회와의 융합을 위해 학교를 기반으로 고위험 문제행동을 보이는 초등학생을 대상으로 실시한 구조화된 인지행동 중재 프로그램의 효과에 관한 예비연구이다. 개발한 프로그램은 준전문가를 통해 실시하여 효과를 검증하였다. 고위험군 선별을 위해 도농복합지역의 한 초등학교 3학년 전체 102명을 대상으로 한국판 아동행동평가척도(K-CBCL)를 실시하였고 문제행동증후군 척도의 T점수가 60점 이상인 고위험군 학생 32명을 선정하여 개입집단과 대조집단으로 나누었다. 인지행동치료를 기반으로 9회기의 구조화된 집단 프로그램을 개발하였고, 심리상담 전공의 대학원생 및 대학생이 전문가의 지도를 받아 개입집단에게 프로그램을 실시하였다. 개입 후 내재화 집단은 내재화 문제, 불안 및 우울증상이 유의하게 감소되었으며 외현화 집단은 외현화 문제, 공격행동에 유의미한 감소를 보였지만, 혼합형 집단에서는 유의미한 변화가 관찰되지 않았다. 질적인 분석을 통해 점수의 의미를 추가적으로 살펴보았다. 결과에 대한 시사점과 연구의 제한점 그리고 후속연구에 대해 제언하였다.

• Parasites, Hosts and Diseases
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• 제52권4호
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• pp.355-365
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• 2014

The enteric protozoan parasite Entamoeba histolytica is the causative agent of human amebiasis. During infection, adherence of E. histolytica through Gal/GalNAc lectin on the surface of the amoeba can induce caspase-3-dependent or -independent host cell death. Phosphorylinositol 3-kinase (PI3K) and protein kinase C (PKC) in E. histolytica play an important function in the adhesion, killing, or phagocytosis of target cells. In this study, we examined the role of amoebic PI3K and PKC in amoeba-induced apoptotic cell death in Jurkat T cells. When Jurkat T cells were incubated with E. histolytica trophozoites, phosphatidylserine (PS) externalization and DNA fragmentation in Jurkat cells were markedly increased compared to those of cells incubated with medium alone. However, when amoebae were pretreated with a PI3K inhibitor, wortmannin before being incubated with E. histolytica, E. histolytica-induced PS externalization and DNA fragmentation in Jurkat cells were significantly reduced compared to results for amoebae pretreated with DMSO. In addition, pretreatment of amoebae with a PKC inhibitor, staurosporine strongly inhibited Jurkat T cell death. However, E. histolytica-induced cleavage of caspase-3, -6, and -7 were not inhibited by pretreatment of amoebae with wortmannin or staurosporin. In addition, we found that amoebic PI3K and PKC have an important role on amoeba adhesion to host compartment. These results suggest that amebic PI3K and PKC activation may play an important role in caspase-independent cell death in Entamoeba-induced apoptosis.

• 중소기업융합학회논문지
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• 제1권1호
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• pp.75-83
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• 2011

Unified Modeling Language (UML)는 산업계에서 소프트웨어 설계 표준 언어로서 인정되고 있으며 특히 UML State Machine Diagram은 클래스의 동적인 행위(behavior)를 묘사하는데 많이 사용되고 있다. 이 논문은 UML State Machine Diagram을를 이용하여 시스템의 데드락 (deadlock)을 찾는 방법에 대해서 논한다. 보통 State Machine Diagram는 개별의 클래스의 행위를 나타내는 데 사용되므로 시스템 범위의 행위를 알고 싶으면 시스템에 있는 클래스들 중 관심 있는 클래스들의 State Machine Diagram을 합하여 시스템의 행위를 나타낼 수 있는 State Machine Diagram이 필요하여진다. 일반적으로 이러한 시스템 수준의 State Machine Diagram은 매우 복잡하고 실제로는 타당하지 않은 State나 Transition들을 포함하게 된다. 실제 시스템의 행위를 나타내기 위해서 synchronization과 externalization을 적용하여 State Machine Diagram을 유효한 수준으로 줄이는 것이 필요하다. 이렇게 만들어진 State Machine Diagram은 시스템의 행위를 나타내는데 사용될 수 있으며 통상의 모델 체킹 방법이 적용될 수 있다. 이 논문은 데드락 탐지를 하는 방법을 간단한 예제를 통해서 보여준다. 모든 과정은 툴에서 자동으로 지원되며 필요한 알고리즘도 같이 설명된다.

• 한국경제지리학회지
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• 제11권3호
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• pp.334-349
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• 2008

본 연구에서는 고령친화산업의 개인 행위주체 네트워크 형성 과정을 지식창출 과정(SECI/ba 모델)에 적용하여 분석하였다. 고령친화산업과 관련된 해외탐방단, 세미나, 심포지엄, 각종 협의회, 교육프로그램, 사이버공간의 포럼 등은 사회화, 외부화, 종합화, 내면화 과정을 가능하게 하는 장(場)을 제공하였다. 이러한 만남의 장(시작의 장, 상호작용의 장, 사이버 장, 실행실습의 장)을 통해서 개인 행위주체들은 동일 지역에 입지하지 않더라도 네트워크를 형성할 수 있는 기회를 가질 수 있었다. 네트워크 형성 과정을 공간적 측면에서 고찰해 보면, 개인의 이동성을 이용한 일시적 지리적 근접성이 중요하고, 이를 통해 개인 행위주체들은 대면접촉을 통해 관계를 형성하고 네트워크를 구축할 수 있었다. 또한 인터넷 커뮤니티 등 가상공간에서의 만남이 네트워크 형성에 중요한 영향을 미치고 있었다.

• 한국초등과학교육학회지:초등과학교육
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• 제38권4호
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• pp.484-495
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• 2019

This study divided pre-service elementary school teachers' knowledge conversion into four types, socialization, externalization, combination and internalization, based on their inquiry activities on the life cycle of cabbage butterfly. As research subjects, this study collected results from 24 pre-service elementary school teachers who carried out inquires on the life cycle of cabbage butterfly for about 2 months. The type of socialization indicates the conversion of tacit knowledge into tacit knowledge, and this study found out that pre-service elementary school teachers acquired and accumulated tacit knowledge from their fellow pre-service teachers, professors and even acquaintances inside and outside the lab. However, there appeared no process that they shared their tacit knowledge with other pre-service teachers or delivered it to them. The type of externalization indicates the conversion of tacit knowledge into explicit knowledge, and this study discovered some cases that pre-service elementary school teachers expressed their inner tacit knowledge into explicit knowledge. However, there was no case found that they converted the verbally-unexpressed tacit knowledge of their fellow teachers or experts into well-defined explicit knowledge. The type of combination indicates the conversion of explicit knowledge into explicit knowledge, and this study discovered some cases that they collected explicit knowledge and converted it into new explicit knowledge for the acquisition, integration and delivery or distribution of explicit knowledge. However, there were few cases that they creatively devised new explicit knowledge by acquiring new knowledge through direct observation and supplementing the existing explicit knowledge. The type of internalization indicates the conversion of explicit knowledge into tacit knowledge, and this study discovered both explicit knowledge embodied through personal experiences and explicit knowledge embodied through simulations and experiments that formed tacit knowledge in process of examining the existing explicit knowledge.

• 한국생활과학회지
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• 제15권1호
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• pp.17-29
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• 2006

This study investigated the behavior problems of children, both institutionalized and home-reared, depending on their sex, age, and entry to institution. The subjects included 621 children (274 institutionalized, 347 home-reared; 298 boys and 323 girls; 209 preschoolers, 223 first to third graders, 189 fourth to sixth). The data collected were analyzed with t-test, 3-way ANOVA, Scheffe test, and Pearson's correlation. Children's emotionality had two sides: Positive (happiness) and negative (sadness, anger, and fear). Measures of behavior problems included internalization (anxiety, immaturity, withdrawal, physical symptom) and externalization (hyperactivity, aggression). The results of this study indicated that the institutionalized were higher in negative emotionality than their counterparts, whereas the home-reared higher in positive emotionality. The institutionalized children also had higher externalizing problems than the home-reared. Furthermore, children's negative emotionality was positively related to their internalizing and externalizing behavior problems, while their positive emotionality was negatively related to the internalizing behavior problems.

• 한국지역사회생활과학회지
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• 제25권3호
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• pp.303-319
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• 2014

This study considers structural equation model and examines the-relationships between various model variables to identify the causal relationships of between the attention span temperament, affectionate rearing attitudes of mothers, and family support (individual external variables) to children's behavioral problems though self-reliance, psychological variable. According to the results, the attention span temperament had significant direct, indirect, and total effects on the externalization of behavioral problems, but affectionate rearing attitudes and family support had only significant indirect effects. Self-resilience had a significant direct effect. These results can be used as basic data to prevent behavioral problems of children and increase their self-resilience.

• Biomolecules & Therapeutics
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• 제8권1호
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• pp.22-26
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• 2000

In order to study the cytotoxic properties of sesquitepenes, dehydrocostus lactone (DL) and costunolide from Saussurea lappa, cytotoxicity was measured by SRB method using various human cancer cell lines. Dehydrocostus lactone(DL) and costunolide exhibited significant cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT 15 cells. The U937 human leukemia cells treated with DL showed several apoptotic evidences like chromosome condensation and formation of apoptotic bodies. From the results of FACS analysis, early apoptosis was observed by phosphatidylserine externalization detected by annexin V-FITC. Furethermore, these studies determined hypodiploid contents and effects on the cell phase distribution of DL-treated U937 cells. After exposure of U937 cells to $30\mu\textrm{M}$ DL effectively led to G2/M modified cell cycle distribution within 24hr. These observations suggest that DL can be used efficiently for the cancer treatment.

• 아동학회지
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• 제21권1호
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• pp.19-33
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• 2000

This study explored the relationship between peer support, strategies used to cope with interpersonal stressors, and social skills among 4th and 5th graders. Instruments were the Social Support Appraisal Scale, the Self-Report Coping Scale, and the Teenage Inventory of Social Skills. Results showed that children used different coping strategies by the level of peer support. Children with more peer support were more active in seeking social support and in solving peer conflict. Children with more problems in peer relationships used more avoidance strategies such as internalization and externalization. Children with a high level of social skills were more likely to use approach strategies in peer conflict while children with a low level of social skills were more likely to employ avoidance strategies. Internalization was the most important strategy in explaining inappropriate peer relationships. For girls, social skill was the most essential variable in their peer relationships.

• 한국시스템다이내믹스연구
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• 제11권1호
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• pp.103-131
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• 2010

This paper aims to investigate a dynamic mechanism underlying the process of knowledge creation and growth with a focus on the 'knowledge-friendly culture' conceptually coined by Davenport and Prusak in 2000. To achieve this objective, key attributes of knowledge are first identified by exploring the generic characteristics and information and interpreting the definitions of knowledge, from which four modes of knowledge growth (Socialization, Externalization, Combination, Internalization) are delineated into a dynamic SECI model by identifying cultural attributes underlying each mode and modeling their casual relationships based on the systems thinking. Further, a series of sensitivity analysis through computer simulation were made to find how 'knowledge-friendly' cultural factors affect the knowledge growth. It is found that individual knowledge is most influenced by organization's cohesion whereas organizational knowledge is most affected by the openness of organization.