• Title/Summary/Keyword: external irradiation

Search Result 241, Processing Time 0.03 seconds

Dosimetric Plan Comparison of Accelerated Partial Breast Irradiation (APBI) Using CyberKnife

  • Lee, Chang Yeol;Kim, Woo Chul;Kim, Hun Jeong;Lee, Jeongshim;Park, Seungwoo;Huh, Hyun Do
    • Progress in Medical Physics
    • /
    • v.29 no.2
    • /
    • pp.73-80
    • /
    • 2018
  • Accelerated partial breast irradiation (APBI) is a new treatment delivery technique that decreases overall treatment time by using higher fractional doses than conventional fractionation. Here, a quantitative analysis study of CyberKnife-based APBI was performed on 10 patients with left-sided breast cancer who had already finished conventional treatment at the Inha University Hospital. Dosimetric parameters for four kinds of treatment plans (3D-CRT, IMRT, VMAT, and CyberKnife) were analyzed and compared with constraints in the NSABP B39/RTOG 0413 protocol and a published CyberKnife-based APBI study. For the 10 patients recruited in this study, all the dosimetric parameters, including target coverage and doses to normal structures, met the NSABP B39/RTOG 0413 protocol. Compared with other treatment plans, a more conformal dose to the target and better dose sparing of critical structures were observed in CyberKnife plans. Accelerated partial breast irradiation via CyberKnife is a suitable treatment delivery technique for partial breast irradiation and offers improvements over external beam APBI techniques.

The Effects of Baickbujasan Extract on the Skin Damage and Pigmendation Induced by Ultraviolet Irradiation (백부자산(白附子散)이 자외선 조사된 피부 손상과 색소침착에 미치는 영향)

  • Kim, Ji-Hoon;Hong, Seong-Ug
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.21 no.1
    • /
    • pp.70-82
    • /
    • 2008
  • Objective : The purpose of this study is to examine the effects of Baickbujasan(BB) on the skin damage and depigmentation. Method : The inhibition of tyrosinase activity, melanogenesis and cell viability in cultured B16 melanoma cells were measured. In order to test effects of reduction of melanogenesis, B16 F-10 mouse melanoma stem line was employed to extract melanin from cultured cell, where BB was added or not, and was dissolved in alkali for colorimetric analysis. Also, in order to test skin alteration in C57BL/6 after UV irradiation, the animals were grouped into a UV urradiation group and UV irradiation after BB application group. Dopa oxidase tissue staining was excuted to invesitage the change in the distribution of active melanin cell. The distribution of active melanin cell in inner skin of iNOS after damage from UVB irradiation and the manifestation condition of P53 which takes part in natural death of keratinocyte were examined. Result : The results indicate that BB has significant effects on tyrosinase activity, and melanogenesis in vivo test. BB seems to reduce C57BL/6, external dermatological damage, for instance, erythematous papule, eczema, loss of keratinocyte, reduction in pus, and relieves dermatological damages. Conclusion : BB can be applied externally for UV protection and depigmentation.

  • PDF

Radiation Therapy of Head and Neck Cancer with CO-60 HDR Transcatheteric Irradiation (고선량율 강내 조사를 이용한 두경부암의 방사선 치료)

  • Shin, Sei-One;Kim, Sung-Kyu;Kim, Myung-Se
    • Journal of Yeungnam Medical Science
    • /
    • v.7 no.2
    • /
    • pp.109-114
    • /
    • 1990
  • The basic strategy of irradiation is to deliver a dose to the cancer that is high enough to make cancer cells incapable of reproduction, while keeping the doses to the various healthy tissues below tolerable levels. In order to improve local control and survival, as a boost therapy after external radiotherapy, high dose rate transcatheteric irradiation using remote control afterloading system(RALSTRON-20B) was used for twelve patients with head and neck cancers. Present results showed complete remission of cancer in 9 out of 12 patients without treatment related complications. Although this procedure is easy to operate, well trained skillful hand is essential for good results. Furthermore our experience suggested that meticulous treatment planning should be developed for better results.

  • PDF

Detection of Irradiated Model Food Containing Salt by Thermoluminescence Measurement

  • Chung, Hyung-Wook;Kwon, Joong-Ho
    • Preventive Nutrition and Food Science
    • /
    • v.3 no.1
    • /
    • pp.22-26
    • /
    • 1998
  • Model food containing common salt(NaCl) was subjected to the thermoluminescene(TL) detection whether it is irradiated or not. Salt irradiated with $^60Co$-gamma ray and electron beam exhibited a characteristic TL gowcurve depending on the irradiation dose, showing major peaks at $206^{\circ}C$ and $326^{\circ}C$. The intensity of TL glowcurves was directly proportional to the irradiated doses regardless of irradiation sources at each concentration of salt. A high correlation coefficient was observed for irradiated salt between the irradiation doses and the corresponding TL responses. At the same dose, the intensity of TL glowcurve increased as the concentration of salt increased in the test sample. TL glowcurves of nonirradiated salt and irradiated model food without salt were negligible and similar to a baseline . However, irradiated model food containing salt gave rise to a characteristic TL glowcurve with two major peaks at about $240^{\circ}C$ and $300^{\circ}C$, respectively. The results showed that salt played a role as an internla as well as external indicator in TL measurements, indicating that TL will be applicable to other condiments and spices with salt for their detection whether they are irradiated or not.

  • PDF

Analysis of Characteristic of Wound Therapy Apparatus using ${\mu}$-Controller (마이크로컨트롤러를 이용한 창상 치유기의 특성 평가)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil;Lee, Ho-Sik;Kim, Tae-Gon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2007.11a
    • /
    • pp.497-497
    • /
    • 2007
  • We developed the light medical therapy apparatus for external injury cure using a ${\mu}$-controller. This equipment was fabricated by using a high brightness LEDs and a ATmega 128, and designed to enable us to control irradiation timer, intensity and reservation. Especially, to control the light irradiation frequency, and to control the change of output value, TLC5941 was used. Control stage is divided into 4 step by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and the output of a high brightness LEDs could be controlled, stage by stage. In this paper, the designed device was used to find out how a high brightness LEDs light source affects the skin wound of a small animal. In result, compared with none light irradiation animal, the lower incidence of inflammation and faster recovery was shown in light irradiation animal.

  • PDF

Comparison of Muscle Activity in the Contralateral Lower Extremity from the PNF Arm Pattern and Leg Pattern (PNF 팔·다리 패턴에 따른 반대측 다리의 근활성도 비교)

  • Kim, Hee-Gwon
    • PNF and Movement
    • /
    • v.15 no.2
    • /
    • pp.177-183
    • /
    • 2017
  • Purpose: This study compared and analyzed the effect of the proprioceptive neuromuscular facilitation (PNF) arm extension pattern and leg flexion pattern on the contralateral lower extremity muscles when the patterns were applied to the same subject. Methods: In the study, 35 healthy men and women who understood the PNF patterns were selected as participants. The participants completed the PNF arm extension-abduction-internal rotation pattern and leg flexion-adduction-external rotation with knee flexion pattern in the supine position. While the patients' completed each pattern, the contralateral leg muscle activity was measured to examine the irradiation effect. The maximum isometric contraction time of the muscles to be measured was kept for 5 seconds, and the mean value was obtained by repeating the pattern three times. Results: When the leg flexion-adduction-external rotation with knee flexion pattern was completed, the muscle activity in the vastus lateralis, vastus medialis, biceps femoris, tibialis anterior, and gastrocnemius of the contralateral lower extremity was significantly greater than that found in the PNF arm extension-abduction-internal rotation pattern. Conclusion: The PNF leg flexion pattern showed greater muscle activity on the contralateral lower extremity than the arm extension pattern. Thus, the PNF leg extension pattern is more effective in the activation of the muscles associated with weight-bearing activity.

A Study on the Fire Hazards of Puzzle Mats in Group Day Care Home (놀이방 퍼즐매트의 화재위험성에 관한 연구)

  • Park, Hyung-Ju
    • Journal of the Korean Society of Safety
    • /
    • v.23 no.5
    • /
    • pp.73-78
    • /
    • 2008
  • The fire hazards and combustion heat of puzzle mats in group day care home were analysed using variable external irradiation level. The fire hazards such as ignition time, ignition temperature, mass loss rate, and flame temperature profile were measured. Incident heat fluxes of $15kW/m^2$, $20kW/m^2$, $25kW/m^2$, $35kW/m^2$, $50kW/m^2$ and $75kW/m^2$ were selected for these experiments. All samples were tested in the horizontal orientation and were wrapped in a single layer of aluminium foil. Each sample was nominally 20mm thick and 100mm square. Five samples of puzzle mat were tested in the study : Type A, B, C, D and E. Type A, B and C are all general grades whereas Type D and E are both Flame retardant grades. As results, Type E of FR-grade showed the best characteristics in safety of the early fire from ignition time, critical heat flux, and ignition and flame temperature data of this study. All specimen of G-grade(Type A, B and C), however, showed the weak in safety of fire.

Radiation testing of low cost, commercial off the shelf microcontroller board

  • Fried, Tomas;Di Buono, Antonio;Cheneler, David;Cockbain, Neil;Dodds, Jonathan M.;Green, Peter R.;Lennox, Barry;Taylor, C. James;Monk, Stephen D.
    • Nuclear Engineering and Technology
    • /
    • v.53 no.10
    • /
    • pp.3335-3343
    • /
    • 2021
  • The impact of gamma radiation on a commercial off the shelf microcontroller board has been investigated. Three different tests have been performed to ascertain the radiation tolerance of the device from a nuclear decommissioning deployment perspective. The first test analyses the effect of radiation on the output voltage of the on-board voltage regulator during irradiation. The second test evaluated the effect of gamma radiation on the voltage characteristics of analogue and digital inputs and outputs. The final test analyses the functionality of the microcontroller when using an external, shielded voltage regulator instead of the on-board voltage regulator. The results suggest that a series of latch-ups occurs in the microcontroller during irradiation, causing increased current drain which can damage the voltage regulator if it does not have short-circuit protection. The analogue to digital conversion functionality appears to be more sensitive to gamma radiation than digital and analogue output functionality. Using an external, shielded voltage regulator can prove beneficial when used for certain applications. The collected data suggests that detaching the voltage regulator can extend the lifespan of the platform up to approximately 350 Gy.

Residual, Unresectable and Recurrent Rectal Cancer : Role of External Radiation Therapy in 46 Patients (국소 재발성 또는 진행된 직장암의 방사선 치료 -46예의 치료 성적 분석-)

  • Gil, Hack-Joon;Oh, Yoon-Kyeong;Yoon, Sei-Chul;Shinn, Kyung-Sub;Bahk, Yong-Whee
    • Radiation Oncology Journal
    • /
    • v.6 no.1
    • /
    • pp.55-61
    • /
    • 1988
  • Fifty patients with residual, unresectable or recurrent rectal cancer were treated with external irradiation using a 6-MV linear accelerator at the Division of Therapeutic Radiology, Department of Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College during the period of April 1983 to December 1987. This paper describes the results of a retrospective analysis of the results of external irradiation for the residual, unresectable and recurrent rectal cancer in 46 patients. Four patients were lost to follow-up. Of the 46 patients, $18 (39\%)$ presented with unresectable primary lesions and $28 (61\%)$ with residual or recurrent rectal cancer. In $93\%$, the pathologic diagnosis was adenocarcinoma. Resonse to irradiation was observed in $22 (73\%)$ out of 30 patients who were treated for pain, $12 (86\%)$ out of 14 patients who were treated for mass, and $17 (77\%)$ out of 22 patients who were treated for bloody discharge. The actuarial postoperative 2-year and 3-year survival rates in recurrent and unresectable patients were $43\%$ and $22\%$, respectively. However, the post-RT 2-year survival rate was $13\% (6/46)$.

  • PDF