• Environmental Analysis Health and Toxicology
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• 제19권4호
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• pp.359-366
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• 2004

Iron (Fe) is an essential metal in biological processes, which maintains a homeostasis in the human body. Divalent metal transporter 1 (DMT1) has been known as an iron transporting membrane protein, which is involved in the uptake Fe at the apical portion of intestinal epithelium, and may transport Fe across the membrane of acidified endosome in peripheral tissues. In this study, we studied the tissue distribution of DMT1 in the Fe supplemented (FeS) diet fed rats, and the regulation of DMT1 expression by depleting body Fe. Sprague-Dawley rats were divided into two groups, and fed FeS (120 mg Fe/kg) diet or Fe deficient (FeD, 2∼6 mg Fe/kg) diet for 4 weeks. The evaluation of body Fe status was monitored by measuring sFe, UIBC and tissue Fe concentration. Additionally, DMT1 mRNA levels were analyzed in the peripheral tissues by using the quantitative real time RT-PCR method. In the FeS diet fed rats, the tissue Fe was maintained at a relatively high level, and DMT1 was eventually expressed in all tissues studied. DMT1 was highly expressed in the testis, kidney and spleen, while a moderate levels of DMT1 expression was detected in the brain, liver and heart. In the digestive system, the highest level of DMT1 was found in the duodenum. Feeding the FeD diet caused a reduced body weight gain and depletion of body Fe with finding of decreased sFe, increased UIBC and decreased tissue Fe concentration. The depletion of body Fe upregulated DMT1 expression in the peripheral tissue. The expression of DMT1 was very sensitive to the body Fe depletion in the small intestine, especially in the duodenum, showing dramatically higher levels in the FeD rats than those of the FeS group. In the FeD diet fed animals, the expression of DMT1 was low significantly in other tissues compared with the duodenum. The expression of DMT1, however, was 60∼120% higher in the testis, kidney and spleen, and 30∼50% higher in the lung, liver and heart, compared to the FeS diet fed rats. In summary, DMT1 expression was ubiquitous in mammalian tissue, and the level of expression was the organ-dependent. The expression of DMT1 in peripheral tissues was upregulated by depletion of body Fe. Duodenum was the most sensitive tissue among organs studied during Fe depletion, and expressed the greatest level of DMT1, while other tissues were less higher than in duodenum. This study supports that DMT1 plays a role in maintaining the body Fe level through intestinal uptake as well as homeostasis of Fe in the peripheral tissue.

• Mycobiology
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• 제43권3호
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• pp.327-332
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• 2015

Phenylalanine ammonia-lyase (PAL) gene is known to be expressed in plants, and is involved in the differentiation, growth and synthesis of secondary metabolites. However, its expression in fungi remains to be explored. To understand its expression in mushroom fungi, the PAL gene of the edible mushroom Flammulina velutipes (Fvpal) was cloned and characterized. The cloned Fvpal consists of 2,175 bp, coding for a polypeptide containing 724 amino acids and having 11 introns. The translated amino acid sequence of Fvpal shares a high identity (66%) with that of ectomycorrhizal fungus Tricholoma matsutake. Distinctively, the Fvpal expression in the mycelium was higher in minimal medium supplemented with L-tyrosine than with other aromatic amino acids. During cultivation of the mushroom on sawdust medium, Fvpal expression in the fruit body correspondingly increased as the mushroom grew. In the fruiting body, Fvpal was expressed more in the stipe than in the pileus. These results suggest that F. velutipes PAL activity differs in the different organs of the mushroom. Overall, this is first report to show that the PAL gene expression is associated with mushroom growth in fungi.

• 동의생리병리학회지
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• 제19권4호
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• pp.1055-1061
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• 2005

In this study, the aim was to investigate the effect of Mahwangpohang-tang on the expression of obesity-related genes and cytokines in high fat diet induced obesity mice. In order to investigate the effects of Mahwangpohang-tang(MHPH) on the obesity-related genes and cytokines, C57BL/6 mice were fed with high fat diet. C57BL/6 mice were divided into three groups and fed for 13weeks. Body weight change, diet intake change, final increase of body weight, the ratio of the adipocyte in body weight, the expression of leptin gene in primary adipocytes, the expression of UCP-2 in primary adipocytes, the production change of $TNF-\alpha$ and leptin in primary adipocytes, the expression of leptin in adipocytes tissue. The body weight of Mahwangpohang-tang(MHPH) intake mice was significantly lower than high fat diet group. The amount of the adipocyte in body weight was decreased Significantly. In primary adipocytes, leptin gene expression and the expression of UCP-2 did not change significantly. In primary adipocytes, the amount of $TNF-\alpha$ was significantly decreased at dose of $100{\mu}/ml$ density. In adipocytes tissue, the expression of leptin did not change significantly. These results suggest that MHPH may inhibit the expression of obesity-related genes and cytokines in high fat diet induced obesity mice

• 한국의상디자인학회지
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• 제25권1호
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• pp.65-81
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• 2023

The purpose of this study is to interpret the semantic actions of body image symbolized in body expression images shown by micro-influencers body profiles to understand the body profile phenomenon of the MZ generation. As a result of collecting body profile data from micro-influencers, the body profile image types of female influencers on SNS were classified into four types, Athletic, Slim body, Natural, and, Glamorous. Images representing each type were analyzed using the Roland Barthes' Myth model analysis frame. As a result of the semantic analysis, influencers were found to be very active and bold, emphasizing certain body parts according to the type of body image they pursue. Fashion is strategically used to emphasize these aspects. It was found that the ideology of a 'subjective modern woman' was commonly expressed through emphasis on visual signs. This study is meaningful in that it can indirectly lead to the understanding the fashion culture expressed by the MZ generation and provide consumer information and essential data that can be used for communication strategies in the fashion market.

• 한국의류학회지
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• 제26권8호
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• pp.1153-1164
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• 2002

The purpose of this study is to find out the creative visual expression in fashion illustration through the previous general theories on creativity. The creative visual expression, in fashion illustration works, can be summarized eight categories as follows. There are 'maximization & minimization'to emphasize the illustrators'emotions and contemporary trends, proposed specially in body expression, 'inversion' seen as the forms of contra-perspective, upside-down, rearrangement of parts, diverted process, etc, 'Unusual uses'to add the effect of caricature, parody, and humor to the fashion illustration works, 'extraordinary connection'seen as the shapes of various combination between animals, plants, stuff, and man, 'concealment & elimination'used frequently in creative visual expression includes a deformed human body, an abstracted human body, an extreme value contrast, simple colors, and dress in silhouette, 'association'seen in various methods; comparing the similar shapes, describing a certain situation or details for analogizing the whole, ‘illusion’ expressed in surreal, mysterious, and fairy depictions and 'substitution'to imitate the composition and colors of masterpieces, copy the parts.

• 복식문화연구
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• 제13권6호통권59호
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• pp.883-895
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• 2005

Exaggeration is to express an object or a situation in an excessive way. As the desire for aesthetic expression grows greater today, we tended to focus on the exaggerative expression as a means to acquire other's attention and praise. Also people more actively express their own intention or opinion in an exaggerated manner. The purpose of this study is to identify the social and cultural functions of modern fashion via exaggerative expression, one of the formative characteristics, and its meaning. To do so, the exaggerative features of modern fashion have been analyzed, and the social and cultural meaning of those have been examined through the background of the times and aesthetic sense. The formative form in the exaggerative expression shown in the modern fashion was classified into a body priority type emphasizing woman's body contour, a body disregarded type shown oversized silhouette regardless of body contour and a body distorted type expressing free and diverse form in various shapes of asymmetry and imbalance. The symbolic meanings of those include the changing of the body consciousness and the notions of feminity, and the desire fur formative and playable expression. The exaggeration of the costume in history meant aesthetic value of the woman's body in the society led by men. However, the exaggerative expression shown in the modern fashion is a method to express more actively, as compared with the costume in the past.

• Animal Bioscience
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• 제35권1호
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• pp.1-12
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• 2022

Objective: FKBP prolyl isomerase 5 (FKBP5) has been shown to play an important role in metabolically active tissues such as skeletal muscle. However, the expression of FKBP5 in Muscovy duck tissues and its association with body weight are still unclear. Methods: In this study, real-time quantitative polymerase chain reaction was used to detect the expression of FKBP5 in different tissues of Muscovy duck at different growth stages. Further, single nucleotide polymorphisms (SNPs) were detected in the exon region of FKBP5 and were combined analyzed with the body weight of 334 Muscovy ducks. Results: FKBP5 was highly expressed in various tissues of Muscovy duck at days 17, 19, 21, 24, and 27 of embryonic development. In addition, the expression of FKBP5 in the tissues of female adult Muscovy ducks was higher than that of male Muscovy ducks. Besides, an association analysis indicated that 3 SNPs were related to body weight trait. At the g.4819252 A>G, the body weight of AG genotype was significantly higher than that of the AA and the GG genotype. At the g.4821390 G>A, the genotype GA was extremely significantly related to body weight. At the g.4830622 T>G, the body weight of TT was significantly higher than GG and TG. Conclusion: These findings indicate the possible effects of expression levels in various tissues and the SNPs of FKBP5 on Muscovy duck body weight trait. FKBP5 could be used as molecular marker for muscle development trait using early marker-assisted selection of Muscovy ducks.

• 한국의류산업학회지
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• 제23권2호
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• pp.200-211
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• 2021

This study examines the effects of fashion influencers' body types (realistic versus ideal body types) on self-expression, self-representation, and recommendation intentions, as mediated by familiarity toward influencers. Although fashion influencers lead to a positive consumer response compared to traditional advertisements, previous research on the effects of fashion influencers on consumers is limited. Thus, this study tests the role of consumers' socio-psychological aspects in understanding how and why fashion influencers affect consumers' behavioral intentions associated with self-expression, self-representation, and influencer recommendation. A total of 180 women in their 20s and 30s participated in the survey. The responses were collected after showing them stimuli featuring fashion influencers with either ideal or realistic body shapes. The data were analyzed using SPSS18.0 for descriptive statistics, and AMOS 18.0 for confirmatory factor analysis and structural equation modeling. The results showed that participants who were shown realistic body types perceived familiarity, which generated positive effects on self-expression, self-representation, and recommendation intentions. Hence, the effects of influencers' body types on recommendation intention are mediated by familiarity. Self-expression and self-representation intentions also increase influencer recommendation intention. Comparatively, participants who were shown ideal body types only induced higher self-representation intention, which increased their recommendation intention. The current findings can help fashion marketers select the appropriate influencers who fit their target customers as promotional models, as well as to induce changes in consumers' behavioral intention.

• 디지털융복합연구
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• 제17권12호
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• pp.289-296
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• 2019

본 연구는 입원한 알콜의존환자가 지각하는 신체상, 정서표현신념 및 의사소통 능력의 정도와 상관관계를 파악하고 의사소통능력에 영향을 미치는 요인을 알아보기 위해 실시하였다. 자료 수집은 J시 소재 2개 정신전문병원과 S시에 소재한 1개 정신전문병원에 입원 중인 151명의 알코올의존 환자들을 대상으로 구조화된 설문지를 이용하였다. 자료수집 기간은 2018년 10월 11일부터 11월 20일 까지였다. 자료는 SPSS/WIN 21.0을 이용하여 T-test, ANOVA, 상관관계 분석과 다중회귀 분석을 사용하였다. 알코올의존 환자의 신체상과 정서표현 신념은 유의한 부적 상관관계, 신체상과 의사소통능력은 정적 상관관계가 있었고. 정서표현신념과 의사소통능력은 부적 상관관계가 있었다. 의사소통능력에 영향을 미치는 요인은 신체상, 학력, 정서표현신념이었고 총 설명력은 24.9%였다. 따라서 알코올의존환자의 의사소통 능력을 향상시키기 위하여 긍정적인 신체상을 가지도록하며 정서표현신념을 낮출 필요가 있다. 본 연구결과가 알코올 의사소통능력을 향상시키는데 기초자료로 활용될 수 있을 것이다.

• 복식
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• 제56권9호
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• pp.24-36
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• 2006

The consumption became a virtue of social in 20th century, and this consumption culture created an ideal body image through mass media. Sexual image became a new standard of 'beauty' in a modern fashion, and designs which expressed sexual image appear every season. Individuals were fascinated with some parts of human body. These body parts are different based on the time period and the culture that the individual belonged to. This study focused on the erotic body parts and expression on the editorial fashion photography. Eroticism represented in the editorial fashion photographs can be divided into the expression by clothing design and by creating erotic atmospheres. Erotic expressions by clothing design can be presented by 1)exposing directly 2)exposing indirectly 3)emphasizing the body parts. The most frequently presented erotic body parts in fashion photographs were legs(25%), followed by the bodice with breast (21%), the waist (16%), the hip (12%), neck & shoulder (10%), arms (9%), and abdomen (7%). The results indicated that legs were considered to be a erotic body parts often than the traditionally referred erotic body parts, such as bodice with breast or hip. While direct exposing method (e.g., adhesion, see-though) was frequently used for other body parts.