• 제목/요약/키워드: exposure pattern

검색결과 457건 처리시간 0.032초

Gene Structure and Estrogen-Responsive mRNA Expression of a Novel Choriogenin H Isoform from a Marine Medaka Oryzias dancena

  • Lee, Sang Yoon;Kim, Dong Soo;Nam, Yoon Kwon
    • Fisheries and Aquatic Sciences
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    • 제15권3호
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    • pp.221-231
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    • 2012
  • The marine medaka Oryzias dancena choriogenin H gene (odChgH) and its mRNA expression during estradiol-$17{\beta}$ (E2) exposure were characterized. At the amino acid level, the choriogenin H protein is predicted to possess the conserved repetitive N-terminal region, as well as zona pellucida (ZP) and Trefoil factor family (TFF) domains. At the genomic level, odChgH has an eight-exon organization with a distribution pattern of transcription factor binding sites in the 5'-upstream region, which is commonly found in other estrogen-responsive genes. The tissue distribution pattern of odChgH mRNA was found to be gender-specific, whereby females showed a higher expression level and wider tissue distribution than did males. During embryonic development, odChgH mRNA was robustly detected from the stage of visceral blood vessel formation. Experimental E2 exposure of males resulted in odChgH mRNA being induced not only in the liver, but also in other several tissues. The E2-mediated induction was fairly dose-dependent. The basal expression levels of hepatic odChgH mRNA were lower in males that were acclimated to 30 ppt salinity than in those acclimated to 0 or 15 ppt salinity. In contrast, the inducibility of odChgH mRNA during E2 exposure was greater in seawater-acclimated fish than in brackish water- or freshwater-acclimated fish.

UVA LED를 이용한 근접 노광용 렌즈 설계 기술 연구 (A Study of Lens Design Technique for Proximity Exposure Using a UVA LED)

  • 이정수;조예지;이현화;공미선;강동화;정미숙
    • 한국광학회지
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    • 제30권4호
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    • pp.146-153
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    • 2019
  • 노광기는 회로 패턴을 원하는 위치에 전사시켜주는 장비로 패턴을 광학적 특성의 변형 없이 기재 상에 나타내기 위해서는 노광광학계의 특성이 매우 중요하다. 따라서 미세회로 패턴을 형성하기 위해서는 조사 면적에 작은 발산각으로 입사되어야 한다. 또한, 광원에서 나온 빛이 감광제와 균일하게 반응해야 하기 때문에 높은 광효율과 조도 균일도를 가져야 한다. 본 논문에서는 협각 구현의 문제점을 해결하기 위한 방법으로 반사형 타입인 파라볼라 반사경과 비구면 렌즈 설계를 진행하였고, 배열 후 시뮬레이션 분석 결과 광속 각도, 균일도, 최대조도가 목표 성능을 만족하는 것을 확인하였다.

2차원 광결정 제작에 패턴 특성을 향상시키기 위한 공정 기술 (Fabrication Technology for Improving Pattern Quality in Two-Dimensional Photonic Crystal Structure)

  • 김해성;신동훈;김순구;이진구;이범석;김혜원;이재은;한영수;최영호
    • 한국전기전자재료학회논문지
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    • 제16권6호
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    • pp.515-521
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    • 2003
  • There are now many theoretical investigations and real manufactures for numerous applications of photonic crystals (PCs) associated with photonic band gap and photonic integrated circuits. However, there are some difficulties to design and fabricate the desired pattern quality. It is not easy to satisfy accurate critical dimension (CD) for patterns with arbitrary shapes and pitch sizes aligned in various directions. In this work, we report the optimum conditions to better fabricate and design, and greatly improve pattern quality in delineating two-dimensional (2D) PCs in the nanometer range using single- step e-beam lithography system with conventional exposure mode.

충남대학교 학술림 산책로 훼손실태 및 관리방안에 관한 연구 (A Study on Trail Deteriorations and Management in University Forest of Chungnam National University)

  • 이준우;김명준;최윤호;전용준;오도교;김민호;이소연;이경형
    • 농업과학연구
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    • 제31권2호
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    • pp.87-96
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    • 2004
  • This study concentrates on the trail of the CNU(Chungnam National University) forest. The amount of use and the pattern of damage are considered, as well as the extent of environmental damage. Finally, some managerial strategies are proposed in connection with sustainable maintenance. The trail of the university forest is composed of three sections; one is the neighborhood park and the Institute of Information Technology/Communications, the second is the Institute of Information Technology/Communications and the Dormitory, and the third section is the Dormitory and the Foreign prof's Apt. The total length of the trail is 2.6km. The daily amount of use is 1,269 visitors per day. The amount of using increased three times the amount of that in 1998. This study shows the pattern of damage of the trail in the order of root-exposure, widening, rock-exposure, deepening and the divergence in the frequency of occurrence of all these factors. Environmental damage is also graded thus: grade 3 is 27.4m, grade 4 is 0.8m, grade 5 is 1.5m, and grade 6 is 0.2m. Accordingly, some managerial strategies were proposed in connection with the sustainable trail maintenance.

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강화도 남단 조간대에서의 수온 및 염분 변동양상 분석 (Water Temperature and Salinity Variation Analysis in the Inter-Tidal Zone, South of Ganghwado, Korea)

  • 조홍연;구본주
    • 한국해안·해양공학회논문집
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    • 제20권3호
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    • pp.310-320
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    • 2008
  • 조간대가 발달한 강화도 남단 여차리, 동막리, 동검도에서의 정점 CTD 관측 자료를 이용하여 수온 및 염분변동 양상 및 원인 분석을 수행하였다. 조간대 관측 자료는 조간대의 침수기간동안의 자료만을 이용하였다. 침수기간동안의 기온자료와 수온자료를 비교분석한 결과 상관관계가 매우 작은 것으로 파악되었으며, 수온변화는 조위의 상승하강과 반대되는 양상을 뚜렷하게 보여 주었다. 반면, 장기적인 지하수 유입의 영향으로 조석주기 동안 해수에서의 염분경사는 해안선에서 바다방향으로 갈수록 증가하는 경향(수온의 경우에는 해안선에서 바다방향으로 갈수록 수온이 감소)이 있기 때문에 수온과는 반대되는 변화양상을 보이고 있다. 즉 조석의 침수기간동안의 염분변화는 침수시점을 기준으로 조위가 상승하여 고조에 도달할 때 까지 증가하고, 조위가 감소하여 노출되는 시점까지 다시 염분이 감소하는 뚜렷한 양상을 보이고 있는 것으로 파악되었다.

Digital Micromirror Device와 Polygon scanner의 Lithography 특성에 따른 산업적 분석 (Industrial analysis according to lithography characteristics of digital micromirror device and polygon scanner)

  • 김지훈;박규백;박정래;고강호;이정우;임동욱
    • Design & Manufacturing
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    • 제15권4호
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    • pp.65-71
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    • 2021
  • In the early days of laser invention, it was simply used as a measuring tool, but as lasers became more common, they became an indispensable processing tool in the industry. Short-wavelength lasers are used to make patterns on wafers used in semiconductors depending on the wavelength, such as CO2 laser, YAG laser, green laser, and UV laser. At first, the hole of the PCB board mainly used for electronic parts was not thin and the hole size was large, so a mechanical drill was used. However, in order to realize product miniaturization and high integration, small hole processing lasers have become essential, and pattern exposure for small hole sizes has become essential. This paper intends to analyze the characteristics through patterns by exposing the PCB substrate through DMD and polygon scanner, which are different optical systems. Since the optical systems are different, the size of the patterns was made the same, and exposure was performed under the optimal conditions for each system. Pattern characteristics were analyzed through a 3D profiler. As a result of the analysis, there was no significant difference in line width between the two systems. However, it was confirmed that dmd had better pattern precision and polygon scanner had better productivity.

디지털 프린팅을 위한 전도성 배선에 관한 연구 (Investigation of Conductive Pattern Line for Direct Digital Printing)

  • 김용식;서상훈;이로운;김태훈;박재찬;김태구;정경진;윤관수;박성준;정재우
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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    • pp.502-502
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    • 2007
  • Current thin film process using memory device fabrication process use expensive processes such as manufacturing of photo mask, coating of photo resist, exposure, development, and etching. However, direct printing technology has the merits about simple and cost effective processes because inks are directly injective without mask. And also, this technology has the advantage about fabrication of fine pattern line on various substrates such as PCB, FCPB, glass, polymer and so on. In this work, we have fabricated the fine and thick metal pattern line for the electronic circuit board using metal ink contains Ag nano-particles. Metal lines are fabricated by two types of printing methods. One is a conventional printing method which is able to quick fabrication of fine pattern line, but has various difficulties about thick and high resolution DPI(Dot per Inch) pattern lines because of bulge and piling up phenomenon. Another(Second) methods is sequential printing method which has a various merits of fabrication for fine, thick and high resolution pattern lines without bulge. In this work, conductivities of metal pattern line are investigated with respect to printing methods and pattern thickness. As a result, conductivity of thick pattern is about several un.

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Expression of Cu/Zn Superoxide Dismutase (Cu/Zn-SOD) mRNA in Shark, Schyliorhinus torazame, Liver during Acute Cadmium Exposure

  • Cho, Young-Sun;Ha, En-Mi;Bang, In-Chul;Kim, Dong-Soo;Nam, Yoon-Kwon
    • 한국양식학회지
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    • 제18권3호
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    • pp.173-179
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    • 2005
  • Superoxide dismutase (SOD), an antioxidant enzyme catalyzing the first step for scavenging the reactive oxygen species is important as an early warning indicator to address various biological stresses. For this reason, the monitoring the expressed pattern of SOD gene in fish organs is one of important biomarkers to assess the aquatic pollution caused by many toxic chemicals. Based on the Northern blot hybridization, semi-quantitative and/or realtime RT-PCRs, the alteration of SOD gene transcripts in shark liver was examined during the experimental acute exposures to cadmium. The expression of SOD at mRNA level was up-regulated both by injection (0, 0.5, 1 or 2 mg $CdCl_2/kg$ body weight for 48 hours) and by immersion (0 or $5{\mu}M$ Cd for 0, 1, 4 and 7 days) treatments of cadmium. The transcriptional stimulation of shark SOD gene by cadmium exposure was dependent upon doses and durations: there was a trend toward more increase in higher dose and longer durations of exposure. The hepatic SOD mRNA levels showed also a general agreement with the tissue cadmium concentrations accumulated in immersion exposure. This result may provide useful strategy to develop a fine molecular biomarker at mRNA level for detecting aquatic pollution caused by toxic metals.

Use of Portable Global Positioning System (GPS) Devices in Exposure Analysis for Time-location Measurement

  • Lee, Ki-Young;Kim, Joung-Yoon;Putti, Kiran;Bennett, Deborah H.;Cassady, Diana;Hertz-Picciotto, Irva
    • 한국환경보건학회지
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    • 제35권6호
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    • pp.461-467
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    • 2009
  • Exposure analysis is a critical component of determining the health impact of pollutants. Global positioning systems (GPS) could be useful in developing time-location information for use in exposure analysis. This study compares four low cost GPS receivers with data logging capability (Garmin 60, Garmin Forerunner 201, GeoStats GeoLogger and Skytrx minitracker MT4100) in terms of accuracy, precision, and ease of use. The accuracy of the devices was determined at two known National Geodetic Survey points. The coordinates logged by the devices were compared when the devices were carried while walking and driving. The Garmin 60 showed better accuracy and precision than the GeoLogger when they were placed at the geodetic points. The Forerunner and Skytrx did not record when they were kept stationary. When the subject wore the devices while walking, the location of the devices differed by about 8 m on average between any two device combinations involving the four devices. The distance between the coordinates logged by the devices decreased when the devices were carried with their antennas facing the sky. All the devices showed similar routes when they were used in a car. All the devices except the Forerunner had satisfactory signal reception when they were worn and when they were carried in the car. The GeoLogger is less comfortable for the subject because of specific wearing requirements. This evaluation found that the Garmin 60 and the Skytrx may be useful in personal exposure analysis studies to record time-location data.

급격한 저염분 노출에 따른 참돔 Pagrus major 치어의 단기 행동반응 및 내성 한계에 관한 연구 (Short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings following sudden low salinity exposure)

  • 윤성진
    • 환경생물
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    • 제39권4호
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    • pp.495-506
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    • 2021
  • In this study, using a continuous behavior measurement technique, the short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings to sudden exposure to low salinity in a controlled environment were observed. The activity of the fingerlings suddenly exposed to 21.4, 17.3, and 9.8 psu increased temporarily at the initial exposure to show irregular swimming behavior, but then recovered a stable activity pattern through rapid salinity adaptation. However, the organisms suddenly exposed to 7.3 and 4.3 psu could not withstand the salinity stress, and their swimming behavior was severely disturbed and all individuals died within 48 hours. The findings suggest that red seabream underwent a temporary salinity stress process at the beginning of the exposure to concentrations of 10.0 psu or higher. At these concentrations, osmotic control was possible within at least 11 hours, so stable metabolic activity was also possible. However, organisms suddenly exposed to concentrations below 5.0 psu exceeded the tolerance to low salinity and the sublethal limit. In red seabream exposed to this concentration range, severe behavioral and metabolic disturbances were observed, and death was observed due to osmotic control failure. In conclusion, a salinity range of 5.0 to 10.0 psu can be predicted to correspond to a concentration range in which the osmotic control ability of the red seabream fingerlings is lost, and sub-lethal reactions occur.