• Title/Summary/Keyword: exposure age

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Projected lifetime cancer risk from cone-beam computed tomography for orthodontic treatment

  • Jha, Nayansi;Kim, Yoon-Ji;Lee, Youngjun;Lee, Ju Young;Lee, Won Jin;Sung, Sang-Jin
    • The korean journal of orthodontics
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    • v.51 no.3
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    • pp.189-198
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    • 2021
  • Objective: To estimate the projected cancer risk attributable to diagnostic cone-beam computed tomography (CBCT) performed under different exposure settings for orthodontic purposes in children and adults. Methods: We collected a list of CBCT machines and their specifications from 38 orthodontists. Organ doses were estimated using median and maximum exposure settings of 105 kVp/156.8 mAs and 130 kVp/200 mAs, respectively. The projected cancer risk attributable to CBCT procedures performed 1-3 times within 2 years was calculated for children (aged 5 and 10 years) and adult (aged 20, 30, and 40 years) male and female patients. Results: For maximum exposure settings, the mean lifetime fractional ratio (LFR) was 14.28% for children and 0.91% for adults; this indicated that the risk to children was 16 times the risk to adults. For median exposure settings, the mean LFR was 5.25% and 0.58% for children and adults, respectively. The risk of cancer decreased with increasing age. For both median and maximum exposure settings, females showed a higher risk of cancer than did males in all age groups. Cancer risk increased with an increase in the frequency of CBCT procedures within a given period. Conclusions: The projected dental CBCT-associated cancer risk spans over a wide range depending on the machine parameters and image acquisition settings. Children and female patients are at a higher risk of developing cancer associated with diagnostic CBCT. Therefore, the use of diagnostic CBCT should be justified, and protective measures should be taken to minimize the harmful biological effects of radiation.

SUMRAY: R and Python Codes for Calculating Cancer Risk Due to Radiation Exposure of a Population

  • Michiya Sasaki;Kyoji Furukawa;Daiki Satoh;Kazumasa Shimada;Shin'ichi Kudo;Shunji Takagi;Shogo Takahara;Michiaki Kai
    • Journal of Radiation Protection and Research
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    • v.48 no.2
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    • pp.90-99
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    • 2023
  • Background: Quantitative risk assessments should be accompanied by uncertainty analyses of the risk models employed in the calculations. In this study, we aim to develop a computational code named SUMRAY for use in cancer risk projections from radiation exposure taking into account uncertainties. We also aim to make SUMRAY publicly available as a resource for further improvement of risk projection. Materials and Methods: SUMRAY has two versions of code written in R and Python. The risk models used in SUMRAY for all-solid-cancer mortality and incidence were those published in the Life Span Study of a cohort of the atomic bomb survivors in Hiroshima and Nagasaki. The confidence intervals associated with the evaluated risks were derived by propagating the statistical uncertainties in the risk model parameter estimates by the Monte Carlo method. Results and Discussion: SUMRAY was used to calculate the lifetime or time-integrated attributable risks of cancer under an exposure scenario (baseline rates, dose[s], age[s] at exposure, age at the end of follow-up, sex) specified by the user. The results were compared with those calculated using another well-known web-based tool, Radiation Risk Assessment Tool (RadRAT; National Institutes of Health), and showed a reasonable agreement within the estimated confidential interval. Compared with RadRAT, SUMRAY can be used for a wide range of applications, as it allows the risk projection with arbitrarily specified risk models and/or population reference data. Conclusion: The reliabilities of SUMRAY with the present risk-model parameters and their variance-covariance matrices were verified by comparing them with those of the other codes. The SUMRAY code is distributed to the public as an open-source code under the Massachusetts Institute of Technology license.

A Study on Noise Exposure Dose and Blood Pressure in an Automobile (모 자동차 공장의 소음폭로와 혈압에 관한 연구)

  • 김성천
    • Journal of Environmental Health Sciences
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    • v.17 no.2
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    • pp.48-53
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    • 1991
  • This study was carried out to investigate age, noise intensity, work period, hearing loss at frequencies, hypertension and to examine correlation of the total quantity of noise exposure(Dose) and blood pressure (Response) in the auto industry during May 1987-December 1987. To perform this study 65 workers were tested. Results of this study were as follows: 1. In frequency analysis, the CS-dip phenomenon occurred around 4000 Hz. 2. Between under of ten years group and over of ten years group, average hearing loss value was statitically significant (P < 0.05). 3. The prevalence of hypertension of 65 workers was 7.84% . 4. At 90dB(A) over and 10 years under and workers in the 20's group, the total quantity of noise exposure (Dose) and systolic blood pressure (Response) were statistically significant (P < 0.05). 5. At under 10 years of work period group, the total quantity of noise exposure(Dose) and diastolic blood pressure (Response) were statistically significant(r =0.234, P < 0.1).

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An Experimental Study on the Durability and Reinforcement Corrosion of Polymer Cement Based Repair Material (폴리머시멘트계 단면복구재의 내구성 및 철근부식특성에 관한 실험적 연구)

  • Kim Young Sun;Kim Young Duck;Na Chul Sung;Cho Bong Suk;Kim Gyu Yong;Kim Moo Han
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.11a
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    • pp.487-490
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    • 2005
  • In this study, for the establishment of the performance evaluation methods and the quality control standards of durability recovery method, the data of indoor durability test and the data of the long term exposure test under the coast are accumulated and analyzed. As a result of the indoor test, durability of repair material was more superior to that of plain concrete, but as a result of investigating and evaluating exposure test at 30 month of exposure age under the coastal environment, the difference in electric potential and the reinforcement corrosion at place replaced with repair material are found.

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Study on Subjective Symptoms that was Complained by Organic Solvent Handling Workers (유기용제 취급의 자각증상호소에 대한 연구)

  • Cheon, Yong-Hee;Moon, Young-Hahn
    • Journal of Preventive Medicine and Public Health
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    • v.17 no.1
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    • pp.295-298
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    • 1984
  • The subjective symptom and other responded relations for 69 male workers handling organic solvent in xxx a pharmacy as exposure group and 87 male workers in noise workshop were studied and analyzied. It was concluded as follows. 1. The age of both exposure group and control group with the subjective symptom indicated a negative correlation. 2. Drinking and smoking of the exposure group complained of the subjective symptom shown the negative correlation and the control group also shown the positive correlation. 3. The occupational experience of the exposure group complained of the subjective symptom indicated the negative correlation and the control group also indicated the positive correlation.

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Occupational Injuries Among Construction Workers by Age and Related Economic Loss: Findings From Ohio Workers' Compensation, USA: 2007-2017

  • Harpriya Kaur;Steven J. Wurzelbacher;P. Tim Bushnell;Stephen Bertke;Alysha R. Meyers;James W. Grosch;Steven J. Naber;Michael Lampl
    • Safety and Health at Work
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    • v.14 no.4
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    • pp.406-414
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    • 2023
  • Background: This study examined age-group differences in the rate, severity, and cost of injuries among construction workers to support evidence-based worker safety and health interventions in the construction industry. Methods: Ohio workers' compensation claims for construction workers were used to estimate claim rates and costs by age group. We analyzed claims data auto-coded into five event/exposure categories: transportation incidents; slips, trips, and falls (STFs); exposure to harmful substances and environments; contact with objects and equipment (COB); overexertion and bodily reaction. American Community Survey data were used to determine the percentage of workers in each age group. Results: From 2007-2017, among 72,416 accepted injury claims for ~166,000 construction full-time equivalent (FTE) per year, nearly half were caused by COB, followed by STFs (20%) and overexertion (20%). Claim rates related to COB and exposure to harmful substances and environments were highest among those 18-24 years old, with claim rates of 313.5 and 25.9 per 10,000 FTE, respectively. STFs increased with age, with the highest claim rates for those 55-64 years old (94.2 claims per 10,000 FTE). Overexertion claim rates increased and then declined with age, with the highest claim rate for those 35-44 years old (87.3 per 10,000 FTE). While younger workers had higher injury rates, older workers had higher proportions of lost-time claims and higher costs per claim. The total cost per FTE was highest for those 45-54 years old ($1,122 per FTE). Conclusion: The variation in rates of injury types by age suggests that age-specific prevention strategies may be useful.

A Study of Working Environment for Automotive Painting in Auto Repair Shops and Workers' Exposure to Hazardous Chemicals (자동차 정비업체 도장공정의 작업환경 및 근로자 노출 실태에 관한 연구)

  • Sim, Sang-Hyo;Jeoung, Chun-Hwa;Lim, Jin-Suk;Lee, Hyung-Gu;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
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    • v.35 no.3
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    • pp.153-161
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    • 2009
  • The purpose of this paper is to evaluate 1) blood lead levels of workers at auto repair shops as Biological Exposure Indices (BEI) of toxic substances such as lead and toluene that are produced during automotive painting process, 2) the differences depending on personal characteristics of workers who have been exposed to toluene by using urine hippuric acid concentration as a marker and 3) the correlation between the concentration of hazardous chemicals in each workplace and the BEL. All subjects were male with a mean age of 36.2 years. In terms of age, most were in the 30 to 40 age group (13 persons, 48.1%). In relation to the length of work experience, the highest proportion had experience of 10 years of less (18 persons, 66.7%). Twenty three workers were cigarette smokers (85.2%) while 4 (14.8%) were non-smokers. In addition, more than 80% of the workers drank alcohol. Dust concentration and toluene exposure during automotive painting showed no significant difference with age, length of work experience, smoking and drinking while a significant difference (p<0.05) has been detected between lead concentration and smoking. The geometric mean of dust concentration, lead concentration and toluene concentration were $0.38mg/m^3,\;0.0021mg/m^3$ and 1.08ppm respectively. In addition, the geometric mean of blood lead levels and urine hippuric acid concentration were $1.70{\mu}g/dl$ and 0.25g/g respectively, which were lower than the standard levels suggested by the Ministry of Labor. To determine the influential factors on blood lead and urine hippuric acid concentrations, a correlation analysis has been conducted with variables of air, lead and toluene concentrations, age, length of work experience and amount of cigarette smoking. According to the analysis, a relatively high correlation (p<0.01) has been observed between air lead concentration and biological sample concentration.

Estimation of ELF-MF Exposure Levels in the Korean Population through 24-Hour Personal Exposure (개인 노출량 조사를 통한 한국인의 극저주파 자기장 노출 수준)

  • Jung, Joon-Sig;Kim, Keun-Young;Hong, Seung-Cheol;Cho, Yong-Sung;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
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    • v.38 no.1
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    • pp.18-30
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    • 2012
  • Objectives: The purpose of this study was to estimate the exposure level to extremely low frequency-magnetic fields (ELF-MF) among a selected Korean population using 24-hour personal exposure measurement. Methods: Participants were randomly selected for the measurement of MF exposure under the assumption that the subjects are representative of the overall Korean population. Levels of personal exposure to MF were measured according to the subject's daily activities. Results: The 24-hour time-weighted average (TWA) of 250 participants was $1.56{\pm}4.56$ mG (GM, GSD: 0.79, 2.46 mG). Personal exposure levels for females were higher than for males. The highest personal exposure level was shown in the age group between 20-60 years old. Personal exposure levels according to job category were higher for the non-occupational group than for the occupational group. Conclusions: Our results showed MF exposure exceeding 2 mG per day among 11.3% of the Korean population, indicating a somewhat higher percentage compared to the EMF RAPID Program's results for the U.S population.

Estimation of Exposure to Boron from Children's Slime Use in Korea (슬라임(액체괴물) 중 붕소 함량과 어린이의 붕소 노출량 추정)

  • Park, Ji Young;Lim, Miyoung;Lee, Kiyoung
    • Journal of Environmental Health Sciences
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    • v.44 no.6
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    • pp.556-562
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    • 2018
  • Objectives: This study was conducted to investigate the boron concentrations in 30 slime products and estimate children's dermal exposure to boron. Methods: Thirty slime products from online and offline stores were purchased for boron analysis. The boron content of each slime sample was analyzed using ICP-OES. A nationwide survey was performed to determine use patterns of slimes by a home-visit survey of 10,000 children divided into three age groups: 0-2, 3-6, and 7-12 years. The dermal exposure to boron was calculated using an exposure algorithm for child slime users. Results: The proportion of the child population using slime was 45.8%, and the mean use frequency was $2.5{\pm}3.8$ per week (range: 0.08-35). Mean time spent playing with slime was $19.6{\pm}11.3min$ (range: 1-100). Twenty-five of the thirty slimes contained a boron concentration exceeding the EU limit for toys made with sticky material of 300 mg/kg. Dermal exposure ranged from $0.0008-13.78{\mu}g/kg/day$ with the maximum weight fractions of boron in the 30 products. The dermal exposure estimate was the highest in 7-12 years old group. Conclusion: Slime use among Korean children may cause high exposure to boron. Regulation is needed to minimize boron exposure from slime products.

Maternal Exposure to Environmental Tobacco Smoke(ETS) and Pregnancy Outcome(low birth weight or preterm baby) in Prospective Cohort Study (임산부 간접흡연과 저체중아 및 조산아 출생에 관한 코호트 연구)

  • Lee, Bo-Eun;Hong, Yun-Chul;Park, Hye-Sook;Lee, Jong-Tae;Kim, Jeong-Youn;Kim, Young-Joo;Kim, Sang-Hyun;Kang, Jung-Goo;Kim, Joo-Oh;Ha, Eun-Hee
    • Journal of Preventive Medicine and Public Health
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    • v.36 no.2
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    • pp.117-124
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    • 2003
  • Objectives : This study was performed to examine the relationship between maternal exposure to environmental tobacco smoke (ETS) and pregnancy outcomes (low birth weight or preform baby) in a prospective cohort study. Methods : We made a pregnant women's cohort, and followed the pregnancy outcomes, between May 1st 2001 and August 31st 2002. We surveyed 2,250 women who visited our hospital during their 35th gestational week, with a self-administered questionnaire. The final total of mother-infant pairs analyzed in this study was 1,712. We used a multiple logistic regression analysis to analyze the effect of maternal ETS on the incidence of preform or low birth weight, and a linear regression analysis for the birth weight and gestational age. Results : Higher exposure to ETS (>=1 hours/day) during pregnancy was more negatively associated with the gestational age and birth weight, than no exposure to ETS (no or less than 1 hour). Maternal exposure to ETS was associated with preform baby(adjusted odds ratio (AOR) 1.7; 95% confidence interval (CI) 0.9, 3.3) and low birth weight (AOR 2.3; 95% CI 0.9, 5.5). In addition, we found that maternal ETS may reduce the birth weight by 70g after adjusting for potential confounding factors. Conclusions : This study suggests that maternal exposure to ETS during pregnancy may increase the frequency of low birth weights and preform births.