• International Commerce and Information Review
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• v.10 no.4
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• pp.47-62
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• 2008

The purpose of this study is to explore the antecedent factors to the piracy of the digital copyrights in order to provide basic data for piracy prevention policy. The findings of study revealed that most respondents had experiences to copy MP3 files illegally. And many respondents answered they didn't copy pirated material by themselves but others did piracy a lot. The feeling of quilt and anxiety against piracy is shown very low level. Low copy cost and regulation level significantly impact upon the cognitive level of other's piracy. Updated contents, the higher price of authenticated materal, piracy regulation are the significant antecedent factors to the level of piracy. The level of piracy activity and anxiety against piracy are significantly different by age. The cognitive level of other's piracy, piracy activity and anxiety are significantly different by gender.

• Journal of Oriental Neuropsychiatry
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• v.12 no.2
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• pp.53-68
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• 2001

This study was performed to investigate the anti-depression effect of Guibiondamtang in rat model of depression. The rats in the experiment were stratified into 3 groups, ie, Guibiondamtang, saline, normal (non-stressed) groups. Chronic exposure to mild unpredictable stress such as white noise, flashing lights and restriction of food and water, causes the behavioral symptoms correspondent to depression. Consumption of 1% sucrose solution fell in rats exposed to CMS for 4 weeks. In the open field test , the exploratory activity ie. locomotion and centering decreased after CMS. We then evaluated the sucrose consumption and activity during 4 weeks of treatment with experimental drugs. The results were as follows: 1) There was no relation between sucrose intake and weight. 2) The Guibiondamtang(歸脾溫膽湯) group reinstated sucrose consumption within 5-6 weeks while having no influence on sucrose intake in normal group. 3) The Guibiondamtang(歸脾溫膽湯) group restored some exploratory activity in the open field test. 4) The Guibiondamtang-group had a-reduced potentiated startle response.

• Advances in Traditional Medicine
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• v.6 no.1
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• pp.34-38
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• 2006

The hot water extract of the seeds of Vernonia anthelmintica Kuntze (Compositae) in a dose of 10 ml/kg body weight of mice, showed significant analgesic activity on the hot plate analgesic method throughout the 4 h experimental period. The hole cross scores and the climbing out scores are of lower than the control animals. The hot water extract reduced the defecation in hole board study and significantly reduces the exploratory ambulation and head dipping behaviour. The seed also showed significant depressant activity on the exploratory ambulation of the open field scores. The drug decreased the spontaneous locomotion activity on brick-chip displacement method up to 45 min and also showed the ability to lessen the amphetamine induced hyperactivity up to 20 min. But it didn't show any effect on pentobarbital induced sleeping time test. The extract reduced gastrointestinal motility.

• Journal of Korean society of Dental Hygiene
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• v.20 no.6
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• pp.913-924
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• 2020

Objectives: This study was conducted to develop a dental hygienist's job satisfaction scale and to evaluate its validity and reliability. Methods: A total of 34 preliminary questions were composed based on the components commonly defined in previous studies and in-depth interviews. Results: The results of the study were practice activity, professional satisfaction, income, working conditions, patient relations, and co-worker relations using the exploratory factor analysis. Goodness of fit of the model assessed using confirmatory factor analysis generally met the criteria. On verification of the internal consistency, the Cronbach's alpha for the factors were as follows: 0.821 for practice activity, 0.822 for professional satisfaction, 0.847 for income, 0.765 for working condition, 0.743 for patient relations, and 0.747 for co-worker relations, which implied that the measurement tool was reliable. Through exploratory and confirmatory factor analyses, a total of 24 items for six factors: six items for practice activity factors, four items for professional satisfaction, three items for income, four items for working conditions, three items for patient relationships, and three items for coworker relations. Conclusions: Based on the aforementioned results, the validity and reliability of the dental hygienist's job satisfaction measurement tool were satisfactory. Thus, it may be used for assessing the job satisfaction of the dental hygienists in future.

• The Korean Journal of Pharmacology
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• v.10 no.2
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• pp.1-11
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• 1974

Results of an experiment on the behavior of rats and mice in order to explore the possible pharmacological actions of Panax ginseng upon the central nervous system can be summarized as follows: 1. Spontaneous motor activity. In the case of mice, those groups who were administered 2.5 mg and 5.0mg of ginseng saponin per kilogram of body weight were observed to have increased their activity compared with the control group, while the 50.0 mg and 100.0 mg per kilogram body weight groups demonstrated lower levels of activity, with the peak of activity appearing at 30 minutes after administration of drugs. In the case of rats, those groups of animals who were given injections in the dosage of 2.5 mg, 5.0 mg and 50.0 mg per kilogram body weight demonstrated higher activity than the control group, while the 100.0 mg per kilogram group appeared to have decreased in their activity, with the peak action appearing 30 minutes after the administration of ginseng saponin. The 50.0 mg per kilogram group demonstrated no significant differential. 2. General behavior analysis. In the case of mice, decrease in sleeping component of behavior and increase in the walking and roaring components, compared those with the control group, turned out to be a common phenomenon among the groups who were administered 2.5 mg, 5.0 mg and 50.0 mg of ginseng saponin per kilogram body weight, with the 5.0 mg per kilogram group standing out of all the other groups in terms of their reactions. In the case of rats, ginseng saponin appeared to reduce sleeping component with 2.5 mg, 5.0 mg and 50.0 mg per kilogram body weight groups, while increased the walking and rearing components. It was observed that administratoin of ginseng saponin in a dose of 2.5 mg per kilogram appeared to markedly increase the lying and grooming components of animal behavior. 3. Open-field exploratory behavior. Adminstration of ginseng saponin to mice in doses of 5.0 mg, 50.0 mg and 100.0 mg per kilogram body weight decreased activity, but increased their exploratory behavior. In the case of rats, however, administration of ginseng saponin in the doses of 2.5 mg and 5.0 mg per kilogram body weight markedly increased their activities, while decreased activities with the 50.0 mg per kilogram and 100.0 mg per kilogram groups. The exploratory behavior of rats appeared to have decreased, while grooming increased ramarkably. 4. The above findings from a series of experiment appear to suggest a stimulating effect on the central nervous system when ginseng saponin is administered in small doses, but that larger doses might result in an inhibitory effect, though differential results can be anticipated with modification of experimental conditions.

• Journal of Microbiology and Biotechnology
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• v.18 no.1
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• pp.171-175
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• 2008

Here, we report that Vibrio parahaemolyticus induces a rapid remodeling of macrophage actin and activates RhoB GTPase. Mutational analysis revealed that the effects depend on type III secretion system 1 regulated translocation of a V. parahaemolyticus effector protein, VP1686, into the macrophages. Remodeling of actin is shown to be necessary for increased bacterial uptake followed by initiation of apoptosis in macrophages. This provides evidence for functional association of the VP1686 in triggering an eat me-and-die signal to the host.

• Natural Product Sciences
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• v.26 no.2
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• pp.165-170
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• 2020

Carica papaya is a medicinal and fruit plant owing biological activities including antioxidant, antiviral, antibacterial and anticancer. The present study aims to investigate the acetyl (AChE) and butyryl (BChE) cholinesterase inhibitory potentials of C. papaya extracts as well as their chemical compositions. The chemical composition of the active extract was identified using a gas chromatography-mass spectrometry (GC-MS). Ellman enzyme inhibition assay showed that the alkaloid-enriched leaf extract of C. papaya possessed significant anti-BChE activity with an enzyme inhibition of 75.9%. GC-MS analysis showed that the alkaloid extract composed mainly the carpaine (64.9%) - a major papaya alkaloid, and some minor constituents such as aliphatic hydrocarbons, terpenes and phenolics. Molecular docking of carpaine revealed that this molecule formed hydrogen bond and hydrophobic interactions with choline binding site and acyl pocket. This study provides some preliminary findings on the potential use of C. papaya leaf as an herbal supplement for the prevention and treatment of Alzheimer's disease.

• Communications for Statistical Applications and Methods
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• v.10 no.3
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• pp.679-694
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• 2003

The purpose of this paper is to develop the Index of Balanced Life from the Korean life style. This paper presents How Koreans live for 24 hours a day, generally. The Index of Life Style is composed of necessary life, duty life and leisure life. Specifically, this paper considers moving time of activity between indexes of balanced life. We suggest that there is a difference among the characteristics, i.e., a sex, week, state of student and region that are explained by analyzing the exploratory data. Thereafter we obtain the statistical inference from each characteristic table.

• Advances in Traditional Medicine
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• v.2 no.2
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• pp.101-105
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• 2002

A battery of neuropharmacological experiments showed the hot water extract of Ocimum sanctum Linn. (Labiateae) had a depressant effect on the central nervous system (CNS), but the aqueous extract showed no effect on it. The hot water extract reduced the spontaneous locomotor activity, exploratory head dipping, propulsive locomotion and exploratory ambulation as well as prolonged the pentobarbital induced sleeping time. The depressant effect starts from 60 minutes after the drug administration and continued to 180 minutes. The drug may exert central depressant effect by interfering with the function of the cortex.

• Journal of Information Technology Services
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• v.10 no.4
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• pp.33-46
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• 2011

This research focus on the economic activity as consumer and producer traits of future customers in the convergence age. We assess level of convergence for digital devices and services respectively by questionnaire survey and interview for 14 professions. And then, for evaluating convergence level and usage of digital services of each respondents, we conducted the questionnaire survey for 343 samples. Findings of our research hold that the group who showed higher level of convergence tends to use the socialized digital services more. Convergence generation were heavy users in appstore on smart-phone and wireless game and more participating. In digital service area, facebook/cyworld, twitter, UCC, portal, internet community in digital service. Convergence generation are global network communication, buying decision making activity, actively opinion expression, prosumer attitude, dependency on digital device, experience based purchase behavior, enthusiastic information sharing.