• Proceedings of the KSRS Conference
• /
• 2008.10a
• /
• pp.437-440
• /
• 2008

In recent years, pollution load calculation has become a topic for research that resulted in the development of numerous GIS modeling methods. The existing pollution method for nonpoint source (NPS) can not be indentified and calculated the amount of the pollution precisely. This research shows that the association of typical pollutant concentrations with land uses in a watershed can provide a reasonably accurate characterization of nonpoint source pollution in the watershed using Expected Mean Concentrations (EMC). The GIS based pollution assessment method is performed for three pollutant constituents: BOD, TN, and TP. First, the runoff grid by means of the precipitation grid and runoff coefficient is estimated. Then, the NPS pollution loads are calculated by grid based method. Finally, the final outputs are evaluated by statistical technique. The results illustrate the merits of the approach. This model verified that GIS based method of estimating spatially distributed NPS pollution loads can lead to more accurate representation of the real world.

• Tuberculosis and Respiratory Diseases
• /
• v.78 no.2
• /
• pp.78-84
• /
• 2015

Background: Reports of therapeutic drug monitoring (TDM) for second-line medications to treat multidrug-resistant tuberculosis (MDR-TB) remain limited. Methods: A retrospective cohort from the Virginia state tuberculosis (TB) registry, 2009-2014, was analyzed for TDM usage in MDR-TB. Drug concentrations, measured at time of estimated peak ($C_{max}$), were compared to expected ranges. Results: Of 10 patients with MDR-TB, 8 (80%) had TDM for at least one drug (maximum 6 drugs). Second-line drugs tested were cycloserine in seven patients (mean $C_{2hr}$, $16.6{\pm}10.2{\mu}g/mL$; 4 [57%] below expected range); moxifloxacin in five (mean $C_{2hr}$, $3.2{\pm}1.5{\mu}g/mL$; 1 [20%] below); capreomycin in five (mean $C_{2hr}$, $21.5{\pm}14.0{\mu}g/mL$; 3 [60%] below); para-aminosalicylic acid in five (mean $C_{6hr}$, $65.0{\pm}29.1{\mu}g/mL$; all within or above); linezolid in three (mean $C_{2hr}$, $11.4{\pm}4.1{\mu}g/mL$, 1 [33%] below); amikacin in two (mean $C_{2hr}$, $35.3{\pm}3.7{\mu}g/mL$; 1 [50%] below); ethionamide in one ($C_{2hr}$, $1.49{\mu}g/mL$, within expected). Two patients died: a 38-year-old woman with human immunodeficiency virus/acquired immune deficiency syndrome and TB meningitis without TDM, and a 76-year-old man with fluoroquinolone-resistant (pre-extensively drug-resistant) pulmonary TB and low linezolid and capreomycin concentrations. Conclusion: Individual pharmacokinetic variability was common. A more standardized approach to TDM for MDR-TB may limit over-testing and maximize therapeutic gain.

• 한국공간정보시스템학회:학술대회논문집
• /
• 2007.06a
• /
• pp.246-251
• /
• 2007

The purpose of this study is to develop a grid based model for calculating the critical nonpoint source (NPS) pollution load (BOD, TN, TP) in Nak-dong area in South Korea. In the last two decades, NPS pollution has become a topic for research that resulted in the development of numerous modeling techniques. Watershed researchers need to be able to emphasis on the characterization of water quality, including NPS pollution loads estimates. Geographic Information System (GIS) has been designed for the assessment of NPS pollution in a watershed. It uses different data such as DEM, precipitation, stream network, discharge, and land use data sets and utilizes a grid representation of a watershed for the approximation of average annual pollution loads and concentrations. The difficulty in traditional NPS modeling is the problem of identifying sources and quantifying the loads. This research is intended to investigate the correlation of NPS pollution concentrations with land uses in a watershed by calculating Expected Mean Concentrations (EMC). This work was accomplished using a grid based modelling technique that encompasses three stages. The first step includes estimating runoff grid by means of the precipitation grid and runoff coefficient. The second step is deriving the gird based model for calculating NPS pollution loads. The last step is validating the gird based model with traditional pollution loads calculation by applying statistical t-test method. The results on real data, illustrate the merits of the grid based modelling approach. Therefore, this model investigates a method of estimating and simulating point loads along with the spatially distributed NPS pollution loads. The pollutant concentration from local runoff is supposed to be directly related to land use in the region and is not considered to vary from event to event or within areas of similar land uses. By consideration of this point, it is anticipated that a single mean estimated pollutant concentration is assigned to all land uses rather than taking into account unique concentrations for different soil types, crops, and so on.

• Korean Journal of Environment and Ecology
• /
• v.24 no.5
• /
• pp.539-546
• /
• 2010

To investigate the variation of anion concentrations in relation to forest type, forest-related factors, forest survey and anion concentrations measurement were carried out on the 52 quadrats located at the national forest areas in Yangyang-gun, Kangwon-do. The relationship between anion concentrations and forest-related factors were correlated. Total mean of anion concentration was 2,405 ea/$cm^3$, which was slightly higher than general figures 2,000ea/$cm^3$. Highly significant positive correlations were observed between anion concentrations and soil moisture contents, and also between anion concentrations and altitude. Significant positive correlations were observed between anion concentrations and topography. Anion concentrations were significantly different among soil moisture levels. Mean anion concentration were highest at 4,524.4ea/$cm^3$ in on wet sites, and followed slightly wet sites and moderate sites. Mean anion concentrations was highest on valley sites at 3,372.4ea/$cm^3$, followed by slope and ridge areas. Mean anion concentrations measured before noon was highest at 3,133.4ea/$cm^3$, and measurements during 12:00~15:00 and after 15:00, showed relatively low anion concentrations. Mean anion concentrations was highest at mixed deciduous forests at 3,503.9ea/$cm^3$, followed by oak forests, pine forests, and pine-oak forests. Results of this study are expected to be used in planning therapeutic forests.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.32 no.4
• /
• pp.425-434
• /
• 2022

Objectives: This study analyzes TVOC concentrations in root industry workplaces in order to prevent probable occupational disease among workers. Root industry includes all the infrastructure of manufacturing, such as casting and molding. Methods: Real-time TVOC sensors were deployed in three root industry workplaces. We measured TVOC concentrations with these sensors and analyzed the results using a data-analysis tool developed with Python 3.9. Results: During the study period, the mean of the TVOC concentrations remained in an acceptable range, 0.30, 2.15, and 1.63 ppm across three workplaces. However, TVOC concentrations increased significantly at specific times, with respective maximum values of 4.98, 28.35, and 26.65 ppm for the three workplaces. Moreover, the analysis of hourly TVOC concentrations showed that during working hours or night shifts TVOC concentrations increased significantly to higher than twice the daily mean values. These results were scrutinized through classical decomposition results and autocorrelation indices, where seasonal graphs of the corresponding classical decomposition results showed that TVOC concentrations increased at a specific time. Trend graphs showed that TVOC concentrations vary by day. Conclusions: Deploying a real-time TVOC sensor should be considered to reflect irregularly high TVOC concentrations in workplaces in the root industry. It is expected that the real-time TVOC sensor with the presented data analysis methodology can eradicate probable occupational diseases caused by detrimental gases.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.4 no.1
• /
• pp.7-16
• /
• 1994

This study was designed to establish the relationship between airborne trichloroethylene concentrations and total trichloro-compounds and trichloroacetic acid in urine samples of the trichloroethylene exposed workers, to examine if the biological screening value for trichloroacetic acid in urine set by the Ministry of Labor is appropriate, and to suggest a suitable biological screening value for total trichloro-compounds in urine. Seventy male workers from the cleaning, the packing, and the inspcetion areas were selected as the study group and eighty male office workers were chosen as the control group. The results were as follows: 1. The mean values of total trichloro-compounds and trichloroacetic acid in the exposed group ($48.1{\pm}1.5mg/{\ell}$, $19.7{\pm}1.9mg/{\ell}$) were significantly higher than those in the control group($4.3{\pm}1.5mg/{\ell}$, $1.8{\pm}1.2mg/{\ell}$). 2. The airborne tichloroethylene concentrations were significantly related with the concentrations of total trichloro-compounds in urine(r=0.8212) and the concentrations of trichloroacetic acid in urine(r=0.7216). 3. The average trichloroethylene concentrations in the manual cleaning plants and that in the automatic cleaning plants were 40.1 ppm and 7.7 ppm, respectively. The difference between two groups was statistically significant. 4. The geometric mean of 49.6 ppm trichloroethylene concentration was resulted in the $185.4mg/{\ell}$ total trichloro-compounds in urine, and the 50 ppm trichloroethylene concentration was expected to produce $170.4{\pm}28.5mg/{\ell}$ total trichloro-compounds in urine. 5. With the geometric mean of 49.6 ppm trichloroethylene concentration, the corresponding geometric mean concentration of trichloroacetic acid in urine was $74.7mg/{\ell}$. In conclusion, the level of personal exposure to trichloroethylene concentration was significantly correlated with the concentrations of total trichloro-compounds and trichloroacetic acid in urine. Current biological screening value of $75mg/{\ell}$ for trichloroacetic acid in urine set by the Ministry of Labor was thought to be appropriate, and a biological screening value for total trichloro-compounds in urine should be set in the range of $170.4{\pm}28.5mg/{\ell}$ as a reference value for trichoroethylene exposure.

• Atmosphere
• /
• v.19 no.3
• /
• pp.227-235
• /
• 2009

Global climate warming induced by long-lived greenhouse gases is expected to cause increases in wildfire frequencies and intensity in boreal forest regions of mid- and high-latitudes in the future. Siberian forest fires are one of important sources for air pollutants such as ozone and aerosols over East Asia. Thus an accurate quantification of forest fire influences on air quality is crucial, in particular considering its higher occurrences expected under the future warming climate conditions. We here use the 3-D global chemical transport model (GEOS-Chem) with the satellite constrained fire emissions to quantify Siberian fire effects on ozone concentrations in East Asia. Our focus is mainly on spring 2003 when the largest fires occurred over Siberia in the past decade. We first evaluated the model by comparing to the EANET observations. The model reproduced observed ozone concentrations in spring 2003 with the high $R^2$ of 0.77 but slightly underestimated by 20%. Enhancements in seasonal mean ozone concentrations were estimated from the difference in simulations with and without Siberian fires and amounted up to 24 ppbv over Siberia. Effects of Siberian fires also resulted in 3-10 ppbv incresases in Korea and Japan. These increases account for about 5-15% of the ozone air quality standard of 60 ppbv in Korea, indicating a significant effect of Siberian fires on ozone concentrations. We found however that possible changes in regional meteorology due to Siberian fires may also affect air quality. Further study on the interaction between regional air quality and meteorology is necessary in the future.

• Journal of Korean Society for Atmospheric Environment
• /
• v.28 no.1
• /
• pp.59-67
• /
• 2012

Platform screen doors (PSD) installed at 289 stations in Seoul metropolitan subway from November 2005 to December 2009, are expected to prevent death from a fall and improve air quality. In this study, we systematically surveyed changes in radon concentrations before and after PSD installation in Seoul metropolitan subway stations. By solid-state nuclear track detectors (SSNTD), the radon concentrations before and after the PSD installation were measured at 54 stations of 6 lines from 2 to 7 reported to have relatively high radon concentrations. Mean radon concentrations at platforms were decreased by approximately 56% from 121.7 Bq/$m^3$ to 54.0 Bq/$m^3$. Before PSD installation, mean radon concentrations were in the decreasing order for subway lines 7, 5, 6, 3, 4 and 2. On the other hand, after PSD installation the order was changed to 5, 6, 7, 3, 4 and 2. According to a radon map of Seoul metropolitan subway, the number of platforms where radon concentration over was 74 Bq/$m^3$ decreased from 38 to 12 after PSD installation.

• Asian-Australasian Journal of Animal Sciences
• /
• v.17 no.6
• /
• pp.784-793
• /
• 2004

Major objective was to evaluate three doses of bST (POSILAC(R)) injected into Holstein cows during the transition period and through 56 d of lactation for potential to improve DMI, BCS, BW, metabolites, hormones, IGF-I and milk production. Biweekly injections of bST (0, 5.1, 10.2, or 15.3 mg bST/d) began 28 d before expected parturition and continued through 56 d postpartum. Twenty-three of the 25 multiparous Holstein cows assigned randomly to four groups completed experiment (7, 5, 6 and 5 cows/group, respectively). The DMI, BW and BCS were recorded weekly throughout the prepartum and postpartum periods and blood samples were collected thrice weekly for analyses of ST, insulin, $T_{4}$, $T_{3}$, IGF-I, glucose and NEFA. Milk yields were recorded daily through 60 d postpartum and milk components measured once weekly. Mathematical model for data analyses for prepartum and postpartum periods included treatment, calving month, and the two-factor interaction. Cows injected with 10.2 and 15.3 mg bST prepartum had greater mean prepartum concentrations of ST and IGF-I. Prepartum injections of bST did not affect prepartum BW or BCS. On average, cows injected postpartum better maintained their BCS during first 60 d of lactation (3.15$\pm$0.06, 3.12$\pm$0.007, 3.20$\pm$0.006 and 3.58$\pm$0.009). Treatments did not affect mean prepartum DMI but cows injected with 15.3 mg bST/d had greatest DMI and greatest mean daily MY during the first 3 wk and tended to be greater during first 60 d of lactation. Cows injected with two highest bST doses (10.1 and 15.2 mg/d) had greater mean postpartum concentrations of ST and $T_{3}$, but IGF-I, $T_{4}$, glucose and NEFA did not differ across groups. No adverse effects of bST treatment were observed.

• Journal of Environmental Science International
• /
• v.28 no.7
• /
• pp.595-606
• /
• 2019

This research investigated the characteristics of CO, $CO_2$, and $NO_2$ concentrations at main subway stations in Busan. The annual mean CO concentrations at the Suyeong and Nampo stations were 0.75 ppm and 0.48 ppm, respectively. Annual $CO_2$ concentration at the Seomyeon 1- platform was 649 ppm. The $NO_2$ concentrations at the Seomyeon 2- waiting room and the Yeonsan station were 0.048 ppm and 0.037 ppm, respectively. CO concentration was highest at two times of the day, and was proportional to the number of passengers commuting to and from work. The CO and $CO_2$ concentrations were highest in winter, but $NO_2$ concentration was highest in spring. CO and $CO_2$ concentrations were highest on Saturday and lowest on Sunday. The correlation of CO and $NO_2$ concentrations measured at the subway stations with those at the ambient air quality station were highest at the Seomyeon 1 and 2- waiting room and Jeonpodong. The correlation was lowest at the Yeonsan and Yeonsandong station. The number of days when $CO_2$ concentration exceeded 700 ppm over the last three years at the Seomyeon 1- platform was 174. The findings of this research are expected to deepen understanding of the fine particle characteristics at subway stations in Busan and be useful for developing a strategy for controlling urban indoor air quality.