• Title/Summary/Keyword: expected efficacy

Search Result 493, Processing Time 0.024 seconds

Examining Synchronous Fluorescence Spectra of Dissolved Organic Matter for River BOD Prediction (하천수 BOD 예측을 위한 용존 자연유기물질의 synchronous 형광 스펙트럼 분석)

  • Hur, Jin;Park, Min-Hye
    • Journal of Korean Society on Water Environment
    • /
    • v.23 no.2
    • /
    • pp.236-243
    • /
    • 2007
  • Fluorescence measurements of dissolved organic matter (DOM) have the superior advantages over other analysis tools for the applications to water quality management due to their rapid analysis. It is known that protein-like fluorescence characteristics are well corelated with microbial activities and biodegradable organic matter. In this study, potential biochemical oxygen demand (BOD) predictor were explored using the fluorescence peak intensities and/or the integrated fluorescence intensities derived from synchronous fluorescence spectra and the first derivative spectra of river samples. A preliminary study was conducted using a mixture of a river and a treated sewage to test the feasibility of the approach. It was demonstrated that the better BOD predictor can be derived from synchronous fluorescence spectra and the derivatives when the difference between the emission and the excitation wavelengths (${\Delta}{\gamma}$) was large. The efficacy of several selected fluorescence parameters was rivers in Seoul. The fluorescence parameters exhibited relatively good correlation coefficients with the BOD values, ranging from 0.59 to 0.90. Two parameters were suggested to be the optimum BOD predictors, which were a fluorescence peak at a wavelength of 283 nm from the synchronous spectrum at the ${\Delta}{\gamma}$ value of 75 nm, and the integrated fluorescence intensity of the first derivatives of the spectra at the wavelength range between 245 nm and 280 nm. Each BOD predictor showed the correlation coefficients of 0.89 and 0.90, respectively. It is expected that the results of this study will provide important information to develop a real-time efficient sensor for river BOD in the future.

Developing a teaching practice program for pre-service teachers using a virtual space (가상공간을 활용한 예비교사 수업실습 프로그램 개발)

  • Park, Jung-Hwan;Cheong, Dong-Uk;Kim, Young-Tae;Yun, Seong-Chul
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.12 no.9
    • /
    • pp.3878-3886
    • /
    • 2011
  • The purpose of this research was to develop a teaching practice program using a virtual space for pre-service teachers reflecting the characteristics of both a virtual space and teaching practice. To develop the program, objectives of the developing, methods of a team grouping, conditions for effective practice were analyzed from literature review and preliminary research. In order to evaluate the effects of the constructed program, the program was applied to 99 pre-service teachers of a university in Korea, and the 46 pre-service teachers participated in the evaluating. The results obtained from the evaluation were that the program brought about the positive change of pre-service teachers' cognition on their teaching efficacy. This program is expected to be effectively used in pre-service teacher education program and connected to the field-based teaching practicum.

A Study on the Verification of Computational Thinking Effectiveness of Understanding-Oriented SW Basic Education Program (이해중심 SW기초교육 프로그램의 컴퓨팅사고 효과성 검증 연구)

  • Oh, Kyung-Sun;Kwon, Jung-In
    • Journal of Digital Convergence
    • /
    • v.17 no.10
    • /
    • pp.23-35
    • /
    • 2019
  • In order to cultivate talented people who have problem solving ability due to computational thinking according to the trend of the fourth industrial revolution, each university is actively promoting software education. This study suggests that understanding-oriented SW curriculum is needed for non-majors students to improve computational thinking. In order to achieve the purpose of the study, this study designed the basic education program based on the understanding of the SW with the backward design model. The SW Basic Education Program was applied to 15 weeks of instruction and conducted three surveys. The positive effects of the understanding-oriented SW basic education on the computational thinking efficacy and the computer perception were verified. In addition, it was found that the understanding-oriented computational thinking and programming education are effective when they are linked to one process. It is expected that understanding-based SW based education, which uses the backward design model, can be applied as one of the efficient ways to improve computational thinking in the education field.

A Review on the Insecticidal Activity of Neem Extracts (Azadirachtin) and its Current Status of Practical use in Korea (님추출물 아자디라크틴의 살충활성과 국내 이용현황에 대한 고찰)

  • Kim, Dong-soon
    • Korean journal of applied entomology
    • /
    • v.60 no.4
    • /
    • pp.463-471
    • /
    • 2021
  • As a tropical plant, the neem tree (Azadirachta indica) has been used for a long time for disease and pest control and medical purposes. In this paper, we reviewed for the active ingredient of neem, the mode of action of azadirachtin in terms of insect growth regulation, repellent, feeding inhibition and oviposition against plant pests. And also we reviewed the current status of practical use in Korea. Among 57 products of neem-based eco-friendly organic agricultural materials distributed in Korea, seven products were certified for their efficacy. The average azadirachtin content of the seven products was 0.38%, which was 5.5 times less than the average content of 2.1% distributed worldwide. In the control effect on neem products in Korea, it showed some variation on aphids, but most showed a control effect of more than 90%. The treatment effects of Lycorma delicatula nymphs were 73-77%, and the control effects for thrips were obtained in the range of 50-72% mortality. The mortality effects against bug and moth species were generally low. It is expected that this review would provide important information necessary for the understanding of distributed neem products and the interpretation of experimental data.

Analysis of factors affecting antibiotic use at hospitals and clinics based on the defined daily dose (병원 및 의원급 일일사용량 기준 항생제 사용량에 영향을 미치는 요인)

  • Lee, Eun Jee;Lee, GeunWoo;Park, Juhee;Kim, Dong-Sook;Ahn, Hyeong Sik
    • Journal of the Korean Medical Association
    • /
    • v.61 no.11
    • /
    • pp.687-698
    • /
    • 2018
  • Inappropriate antibiotic use significantly contributes to antibiotic resistance, resulting in reduced antibiotic efficacy and an increased burden of disease. The objective of this study was to investigate the characteristics of prescribers whose antibiotics use was high and to explore factors affecting the use of antibiotics by medical institutions. This study analyzed the National Health Insurance claims data from 2015. Antibiotic prescription data were analyzed in terms of the number of defined daily doses per 1,000 patients per day, according to the World Health Organization anatomical-therapeutic-chemical classification and methodologies for measuring the defined daily dose. We investigated the characteristics of prescribers and medical institutions with high antibiotic use. Multivariate regression analyses were performed on the basis of characteristics of the medical institution (number of patients, type of medical institution [hospital or clinic], age of the physician, etc.). The number of patients and number of beds were found to be significant factors affecting antibiotic use in hospitals, and the number of patients, region, and medical department were significant factors affecting antibiotic use at the level of medical institutions. These findings are expected to help policy-makers to better target future interventions to promote prudent antibiotic prescription.

Beauty experts' perception awareness of Korean mask packs (한국 마스크팩에 대한 미용종사자들의 인식 조사)

  • Kwon, Hye-Jin
    • Journal of the Korea Convergence Society
    • /
    • v.10 no.3
    • /
    • pp.243-248
    • /
    • 2019
  • This study was designed to prepare measures for future development and growth of local cosmetics industry by examining awareness, purchasing behaviors and satisfaction of beauty professionals with regard to Korean brand mask packs that have recently created a big trend in the beauty market. According to the results of survey, 80.6 percent of the respondents said that the most important factor in buying a mask pack was 'effect,' and as for the needed improvement of mask packs, 33.7 percent responded 'effect,' indicating that consumers still find the function of a product is unreliable. In addition, the respondents said that 'K-beauty effect' was the reason why mask packs were highly popular abroad, especially in China, and items that can promote beauty market were also said to be 'K-beauty advertising and promotion,' so it is believed that a good impression of K-culture rather than its own efficacy or reliability is leading to the present results. Therefore, K-beauty industry is expected to grow further in the global market if domestic and abroad consumers' confidence on the product is gained through the development of superior products that have improved effect and usability.

A Case Study on Convergence-based Mobile English Curriculum (융합기반의 모바일영어커리큘럼에 관한 사례 연구)

  • Kim, Young-Hee;Oh, Seong-Rok
    • Journal of the Korea Convergence Society
    • /
    • v.10 no.8
    • /
    • pp.115-120
    • /
    • 2019
  • This study aims to prove the value of convergence-based mobile English curriculum for English education prior to its practical use. This is deferent from the existing studies in developing and studying a curriculum using an English program loaded in mobile to make an effective English learning. In order to find out how well teachers are aware of this curriculum, we performed qualitative researches. Some English teachers asked for feedback about the curriculum gave us positive feedback in most areas such as learning authentic English, repetition effects, cooperative learning, self-efficacy experience, and so on. As a negative feedback, they were afraid of students' easy and free attitudes because of the new learning environments. This problem can be solved by the very close communications between teacher and student through on and off line. Next time applying this curriculum to the field and analyzing will be expected.

Effect of Intravenous Lipid Emulsion on Clozapine Acute Toxicity in Rats

  • Yousefsani, Bahareh Sadat;Mohajeri, Seyed Ahmad;Moshiri, Mohammad;Jafarian, Amir Hossein;Hosseinzadeh, Hossein
    • Journal of Pharmacopuncture
    • /
    • v.22 no.3
    • /
    • pp.147-153
    • /
    • 2019
  • Objectives: Many studies have been reported the efficacy of intravenous lipid emulsion (ILE) as an antidote on acute lipophilic drug toxicity. Clozapine, highly lipophilic dibenzodiazepine neuroleptics, is an important medication in the schizophrenia therapy regimen. Acute intoxication with antipsychotics is one of the main reasons for the referral of poisoned patients to the hospital. We expected that ILE could be used for the therapy of acute clozapine intoxicated patients. Methods: We used two groups of consisting of six male rats. Both groups received a toxic dose of clozapine (40 mg/kg) intravenously, via the tail vein. After 15 minutes, they were treated with intravenous infusion of 18.6 mg/kg normal saline (NS group), or 18.6 mg/kg ILE 20% (ILE group). We evaluated blood pressure (BP) and heart rate by power lab apparatus through the tail artery, ataxia by a rat rotary circle, seizure scores and death in multiple times after starting clozapine administration. For biochemical and pathological evaluations the samples of tissue and blood were taken. Results: Our results demonstrated that ILE 20% could return hypotension-induced clozapine better than normal saline. Furthermore, ataxia and seizure have rectified more rapidly and deaths reduced. Clozapine administration causes pancreatitis and lung injury but fat emulsion did not show an optimal effect on tissue damages caused by clozapine toxicity. Conclusion: In conclusion, ILE can remove toxic signs of clozapine same as other lipophilic medicines, however, clinical uses of ILE for this intention requires more appraisement to determine the precise implication and safety.

The Effect of Banhasasim-tang in Cough: A Systematic Review and Meta-analysis (기침에 대한 반하사심탕의 효과 : 체계적인 문헌고찰과 메타분석)

  • Han, Seung-hee;Sun, Seung-ho
    • The Journal of Internal Korean Medicine
    • /
    • v.42 no.3
    • /
    • pp.385-402
    • /
    • 2021
  • Objective: This study confirms the safety and efficacy of Banhasasim-tang (BST) against cough through systematic review and meta-analysis. Methods: PubMed, Cochrane, ScienceDirect, Wiley online library, OASIS, KISS, NDSL, RISS, Science and Technology Society Village, DBpia, CNKI, J-STAGE, and CiNii were used as search engines. The search period was from the start of search engine support to June 30. 2020. And search language was not limited. Cochrane's risk of bias (RoB) tool was used to evaluate the quality of the studies. A meta-analysis of the total effective rate (TER), cough symptom score, and spirometry results was performed using the Review Manager program. Results: 6 studies were finally selected. The group using BST showed significant symptom relief, as the odds ratio (OR) value of TER was 5.56 times higher (95% CI: 3.50, 8.82, P<0.0001) compared to the control groups. The reported adverse effects did not occur in the intervention group. In addition, the cough symptom score and spirometry results showed that BST was more effective than Western medicine alone. Conclusion: BST can be expected to relieve cough, and it can be applied to chronic cough that is not treated with existing treatments. However, due to the low quality of the selected articles, additional high-quality RCTs will be required in the future.

Development and application of software education programs to improve Underachievement

  • Kim, Jeong-Rang;Lee, Soo-Hwan
    • Journal of the Korea Society of Computer and Information
    • /
    • v.26 no.1
    • /
    • pp.283-291
    • /
    • 2021
  • In this paper, we propose the development and application of a software education program for underachievers. The software education program for underachieving students was developed in consideration of the characteristics of learner's suffering from underachievement and the educational effects of software education, and is meaningful in that it proposes a plan to improve the learning gap in distance learning. Learners can acquire digital literacy and learning skills by solving structured tasks in the form of courseware, intelligent tutoring, debugging, and artificial intelligence learning models in educational programs. Based on the effects of software education, such as enhancing logical thinking ability and problem solving ability, this program provides opportunities to solve fusion tasks to underachievers. Based on this, it is expected that it can have a positive effect on the overall academic work.