• 제목/요약/키워드: expected efficacy

검색결과 488건 처리시간 0.031초

Anti-Allergic Effect of Fermented Extracts of Medicinal Plants Andrographis paniculate, Salvia plebeia R. Br., Canavalia gladiate, Eleuthorococcus senticosus, Ulmus davidiana var. japonica, and Clerodendrum trichotomum Thunb. ex Murray

  • Mi Jeong, Choi;Yu Ri, Kim
    • 한국미생물·생명공학회지
    • /
    • 제50권4호
    • /
    • pp.512-521
    • /
    • 2022
  • Since the main symptoms of COVID-19 involve the respiratory system, the infection rate of this disease is predicted to be higher in patients with other respiratory conditions such as allergic rhinitis. In such a situation, it will be meaningful to conduct research on an allergy treatment that has fewer side effects and can effectively reduce allergy symptoms. Here, we prepared experimental samples under various fermentation conditions with mixed extracts of six medicinal plants. To examine the anti-allergic efficacy of these samples, an egg albumin-induced allergic rhinitis animal model experiment, a serum histamine and IgE experiment, and a COX and LO inhibitory activity experiment were conducted. As a result of animal experiments, OVA+SP-4 showed superior efficacy compared to OVA+SP-1 in nasal rubbing and sneezing experiments and had anti-allergic efficacy similar to that of OVA-cetirizine. The serum histamine concentration of OVA+SP-4 was also 1.3 times higher than that of the OVA+cetirizine group, showing a high histamine reduction ability, and IgE showed the same trend. An analysis of COX inhibitory efficacy also confirmed that COX-1 and COX-2 inhibitory efficacy is high, and the longer the fermentation time, the higher the antiallergic efficacy. The composition proposed by this study is expected to have a significant effect on sustainable allergy prevention and treatment in the future by applying it to human patients.

일 지역사회 노인의 자기효능, 가족지지와 건강증진 행위와의 관계연구 (A Study on Self-Efficacy, Family Support and Health Promoting Behavior of the Aged in a Community)

  • 최인희
    • 지역사회간호학회지
    • /
    • 제14권4호
    • /
    • pp.657-666
    • /
    • 2003
  • Purpose; This study was conducted to investigate the relationship between self-efficacy, family support and health promotion behavior of the elderly in a community. Method: The sample consisted of 208 elderly and data was collected from November 18 to December 21, 2002. The instrument of this study was a structured questionnaire including health promoting behaviors, self-efficacy, family support, general characteristics. Analysis of the data was done by use of descriptive statistics, t or F, Pearson Correlation Coefficient, Stepwise multiple regression. Results: 1. The general characteristics related to health promoting behavior were gender, family structure, education level and monthly pocket money. 2. The general characteristics related to self efficacy were gender, age, family structure, education level, religion and monthly pocket money. 3. The general characteristics did not affect family support. 4. Health promoting behavior score was the highest in the interpersonal support (2.72) and in order was nutrition(2.65), stress management(2.31), self actualization(2.30), exercise(2.05), health responsibility(1.86). 5. There was a significantly high correlation between health promoting behavior and self efficacy(r= .605, p= .000), and family support(r= .500, p= .000) and between self-efficacy and family support were correlated relatively high(r= .498, p= .000) 6. Stepwise multiple regression analysis revealed that the most powerful predictor of health promotion behavior in elderly was self-efficacy (39.6%). A combination of self-efficacy, family support, monthly pocket money, education level and present illness status explained 48.5% of the variance for health promoting behavior. In conclusion, the results of this study showed that self-efficacy and family support are very important variables in explaining the health promoting behaviors in elderly. Therefore, these variables should be considered in nursing intervention development and education, especially, self-efficacy improving programs that considered exercise and health responsibility are expected to effect the health promoting behavior in elderly.

  • PDF

자기효능증진 운동훈련 프로그램이 신장이식 환자의 불안, 우울 및 삶의 질에 미치는 효과 (The Effects of the Self Efficacy Promotion and Exercise Training Program on Anxiety, Depression and Quality of Life of Kidney Transplant Recipients)

  • 안재현
    • 성인간호학회지
    • /
    • 제13권2호
    • /
    • pp.223-232
    • /
    • 2001
  • The purpose of this study is to develop and evaluate the Self Efficacy Promotion and Exercise Training Program to decrease anxiety and depression and to increase the quality of life for kidney transplant recipients. The subjects were selected randomly among the patients who underwent renal transplant at three major transplantation hospitals in Seoul, Korea. The observed subjects in this study consisted of 56 patients who had renal transplantations between one to twelve months prior to this study. The patients did not take any regular physical exercise. This study was carried out between November, 1999 and March, 2000. The study groups were divided into 3 groups; exercise training group (n=16), self efficacy group (n=18) and control group (n=22). The exercise training group received self efficacy promotion and exercise training program for 12 weeks. The self efficacy group received self efficacy promotion education, but no exercise training was given. The control group was not offered any education. The anxiety, depression and quality of life were evaluated 3 times, before the experiment, after 8 weeks and after 12 weeks. The data were analyzed with mean, standard deviation, Chi-square test, ANOVA and $Scheff\acute{e}$ test. The results were as follows: 1. After the experiment, anxiety and depression scores of the exercise training group and self efficacy group were more significantly decreased than those of the control group (p=.05). 2. After the experiment, the quality of life score of the exercise training group and self efficacy group were more significantly increased than those of the control group (p=.05). This study showed that the Self Efficacy and Exercise Training Programs were effective. Therefore, it is expected that the Self Efficacy Promotion and Exercise Training Program could be widely applied as an effective independent nursing intervention to decrease anxiety and depression and to increase quality of life for kidney transplant recipients.

  • PDF

스마트폰중독 대학생의 자기효능감과 스트레스 대처전략에 관한 연구 (A Study on Sense of Self-efficacy and Stress Encountering Strategy of Smart-phone Addicted University Students)

  • 백유미
    • 디지털산업정보학회논문지
    • /
    • 제13권1호
    • /
    • pp.173-183
    • /
    • 2017
  • The purpose of this study is to find out the difference of sense of self-efficacy and stress encountering strategy of university students under the stress situation depending on the smart-phone user group (addiction group, general user group). For this purpose, the study issues are established as follows. First, it has analyzed what is the correlation of smart-phone addiction, sense of self-efficacy, and stress encountering strategy. Second, it has studied if there is any difference of sense of self-efficacy and stress encountering strategy for the smart-phone user group. In order to verify such study issues, For 1,670 university students in the Chungcheong area, smart-phone addiction scale, sense of self-efficacy scale, and stress encountering method scale were administered. Looking into the study result, first, as a result of the relativity analysis, it displayed the correlation of preference of test difficulty, self-control efficacy and important negative from the smart-phone addiction and sense of self-efficacy. In addition, all sub-variables of smart-phone addiction and avoidance orientation from the stress encountering strategy displayed the important positive correlation, and from the smart-phone addiction, the virtual world orientation and pursuit of social-support displayed the important negative correlations, and all sub-variables (interference with ordinary living, virtual world striving direction, withdrawal, resistance) of smart-phone addiction and problem solving-orientation displayed the negative correlation. Second, as a result of verification for the difference of the smart-phone addiction group and general use group following the sense of self-efficacy, the general use group is shown to have higher self-control efficacy sense than the addiction group. And third, as a result of verifying the difference of stress encountering following the smart-phone addiction group and general use group, the addiction group is shown to be lower than the general use group in terms of social support pursuit and problem solution orientation with the avoidance orientation shown to be higher. This type of result is expected to provide the base data when developing the smart-phone addiction preventive education program by finding out in details for the characteristics of smart-phone addiction group for university students.

수학교사의 수학 학습동기 유발 효능감 측정 도구 개발 연구 (Development of the motivating efficacy scale for mathematics teachers)

  • 김소민;김희정
    • 한국학교수학회논문집
    • /
    • 제26권2호
    • /
    • pp.159-184
    • /
    • 2023
  • 본 연구에서는 학습동기 유발 효능감을 조작적으로 정의한 후, 문헌연구와 전문가 델파이 조사를 통해 수학교사의 수학 학습동기 유발 효능감 측정 도구인 Motivating Efficacy Scale for Mathematics Teachers(MESMT)의 초안을 개발하고, 이 측정 도구의 요인구조를 탐색하고, 타당도와 신뢰도를 검증하기 위해 전국의 초·중등 수학교사 347명의 온라인 설문조사 응답 자료를 사용하여 탐색적 요인분석을 수행하였다. 탐색적 요인분석 결과, 문헌연구와 전문가 델파이 조사 결과를 통해 개발된 초기 42개 설문문항에서 17개 문항이 삭제되고, 4개 요인(성공경험 제공, 주의집중 및 참여 유도, 수학 사례기반 관련성 생성, 외재적 보상 제시), 25개 문항의 최종 MESMT를 도출하였다. 본 연구에서 개발한 MESMT는 타당도와 신뢰도가 검증된 수학교사의 수학 학습동기 유발 효능감 측정 도구로써, 수학 학습동기 유발 효능감에 대한 이해와 수학교사의 수학 학습동기 유발 역량 증진을 위한 많은 후속 연구들의 출발점이 될 것으로 기대된다.

초등학생의 수학 자기 효능감 검사 도구 개발에 관한 연구 (Development and Validation of Mathematics Self Efficacy Scale for Elementary Students)

  • 김리나
    • 한국수학교육학회지시리즈C:초등수학교육
    • /
    • 제23권2호
    • /
    • pp.63-72
    • /
    • 2020
  • 본 연구의 목표는 초등학교 3~6학년 학생을 대상으로 하는 수학 자기 효능감 검사 도구를 개발하는데 있다. 본 연구에서는 문헌연구에서 도출된 수학 자기 효능감 하위 요인을 중심으로 검사 도구 문항을 개발하였다. 이 후 개발된 문항을 초등학교 3-6학년 학생들로 구성된 연구 참여자에게 적용하여 설문 결과를 통계적으로 분석하였다. 특히 본 연구에서는 주성분분석(Principal Component Analysis)을 이용해 설문 도구의 신뢰도를 검증하였다. 타당도 검증을 위해서는 수학 자기 효능감과 음의 상관관계가 있는 수학 불안 상태를 별도로 측정하여, 본 연구에서 개발한 측정도구와의 관계를 통계적 방법으로 분석하였다. 본 연구에서 개발된 초등학생의 수학 자기 효능감 검사도구는 향후 초등학생의 수학 자기 효능감 상태를 진단하고, 이를 토대로 수학 자기 효능감를 증진시키는 방안을 모색하는데 기초 자료가 될 것으로 기대된다.

소셜 네트워크 서비스(SNS) 이용자들의 개인정보보호 행동에 관한 연구: 보호동기이론을 중심으로 (Study on Social Network Service(SNS) Users' Privacy Protection Behavior : Focusing on the protection motivation theory)

  • 김정은;김성준;권두순
    • 한국정보시스템학회지:정보시스템연구
    • /
    • 제25권3호
    • /
    • pp.1-30
    • /
    • 2016
  • Purpose The purpose of this study is to grasp the factors influencing domestic SNS users' privacy protection behavior and verify their relationship through self-efficacy and responsiveness. Thus, this study tries to suggest efficient and effective measures for SNS personal information protection. Design/methodology/approach To this end, with main variables of the protection motivation theory based on the assumption that when users are exposed to the threat to their health, they would have protection motivation and change their behavior of protecting their health, a research model was suggested. In addition, in order to empirically verify the research model, a survey was performed targeting general college students having the experience of using SNS. Findings As a result of the analysis, first, perceived effectiveness and self-efficacy had a positive effect on responsiveness. Second, perceived barrier had a positive effect on self-efficacy. Third, self-efficacy and responsiveness had a positive effect on privacy protection behavior. This study is expected to contribute to establishing an effective guideline for measures that could induce SNS users' privacy protection behavior.

대학교의 정보교육 만족과 성과의 영향변인에 관한 연구 (A Study on the Factors affecting the Satisfaction and Performance of Information Education in College)

  • 전병호
    • 정보교육학회논문지
    • /
    • 제14권4호
    • /
    • pp.477-488
    • /
    • 2010
  • 본 연구의 목적은 정보화 시대의 인재 양성을 위해 대학교에서 실시되는 정보교육의 성과를 증진시킬 수 있는 요인들을 살펴보고자 하는 것으로, 컴퓨터 자기효능감을 중심으로 하는 학습자의 관점과 실습실 및 교수자 특성의 환경 관점으로 구분하여 분석하고자 하였다. 연구 결과에 따르면 환경 측면의 실습실 요인을 제외한 모든 요인(컴퓨터 자기효능감, 혁신성, 동기, 자기조절 효능감, 교수자 특성)이 정보교육성과에 유의한 영향을 미치는 것으로 나타났다. 대학에서의 정보교육성과에 영향을 미치는 요인은 분석은 정보화 사회의 인재양성에 기여할 수 있으며 효과적인 정보교육을 위한 지침을 제공해 줄 수 있을 것이다.

  • PDF

광학이성질체 의약품 개발에서 안전성과 유효성 평가에 대한 규제 요건 (Regulatory Requirements on the Safety and Efficacy Evaluation for the Development of Stereoisomeric Drugs)

  • 김광준;최인;서규화;한효경;이원재
    • 약학회지
    • /
    • 제55권5호
    • /
    • pp.426-431
    • /
    • 2011
  • This study was performed to investigate the current regulatory guidances of safety and efficacy evaluation for the development and approval of stereoisomeric drugs in US, EU, Canada and Japan. The important categories for the development of stereoisomeric drugs are classified as 1) development of a single enantiomer as a new active substance 2) development of a racemate as a new active substance 3) development of a new single enantiomer from an approved racemate. The regulatory documents adopted in major countries for the safety and efficacy evaluation of stereoisomeric drugs were investigated with the focus on three major categories mentioned above. For the regulatory approval of stereoisomeric drugs in Korea, it is expected that the investigated results obtained in this study will be useful for the basic materials to ensure the safety and efficacy of stereoisomeric drugs as well as the stereochemical issues in chiral drug development in domestic pharmaceutical company.

일 대학 여대생의 골 (骨) 건강 관련 지식, 자기효능감 및 건강행위 (Female College Students' Knowledge, Self-efficacy and Health Behaviors related to Bone Health)

  • 오의금;고일선;추상희;이정은;유재용
    • 여성건강간호학회지
    • /
    • 제18권1호
    • /
    • pp.38-48
    • /
    • 2012
  • Purpose: This study described female college students' knowledge, self-efficacy and health behaviors related to bone health. Methods: A descriptive cross-sectional survey design was used. A total of 214 students were conveniently recruited from a school of nursing in Korea. Participants (mean age=21.2, SD=1.9 years) bone mineral density (BMD) was measured using dual energy x-ray absorptionmetry. Participants also completed a questionnaire consisting of knowledge test, self-efficacy scale and health behaviors related to bone health. Data were analyzed using SPSS/WIN 17.0 program. Results: The mean BMD at left femoral neck site was $0.86g/cm^2$ and 6.1~12.6%. Results showed that participants were below the expected range of BMD. Level of knowledge (correct rate=54%) and self-efficacy were moderate (mean 54.8 out of 84). More than 84% of subjects drank alcohol more than once a month and 58.4% did participate in regular exercise. Only 7.9% participants took calcium and vitamin-D rich foods every day. There were significant positive correlations between knowledge and self-efficacy (r=.17), health behaviors (r=.14) and self-efficacy and health behaviors (r=.28, all p<.05). Conclusion: These results suggest that health care professionals need to provide effective interventions for young women in order to enhance knowledge, self-efficacy and health behaviors related to bone health.