• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.113-124
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• 2019

The purpose of the study was to investigate the effects of sea cucumber extract on skin as a natural cosmetics functional material. Subjective evaluation of cosmetics before and after were conducted with questionnaires regarding moisture content, sebum content, melanin index, and erythema index. Experiments were conducted on improvement efficacy using skin clinical trials and questionnaires to evaluate changes in perception of skin condition and efficiency of products. With the aim of minimizing skin irritation, the efficiency of the solvent used for extraction was an important factor, and the sea cucumber extract was harvested with efficient extraction conditions at a ratio of 1:10 of 50% ethanol. The study aimed to identify the suitability of sea cucumber extract as a functional cosmetics material to improve the moisturizing ability of skin and its effect on the skin by adding marine natural animal sea cucumber extract. Clinical studies on cosmetics skin containing sea cucumber extract, excellent skin improvement effect from all items of clinical experiment in experimental and control groups. Sea cucumber extract was proved to be a stable, non-adverse physiologically active substance against abnormal symptoms or side effects of skin reactions and skin problems. In addition, the study found excellent results that can lead to its use as a cosmetics material. This is expected to contribute to the development of various cosmetics industries.

• Mass Spectrometry Letters
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• v.12 no.3
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• pp.85-92
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• 2021

The therapeutic antibody drug market has experienced explosive growth as mAbs become the main therapeutic modality for a variety of diseases. Characterization of glycosylation that directly affects the efficacy and safety of therapeutic monoclonal antibodies (mAbs) is critical for therapeutics development, bioprocess system optimization, lot release, and comparability evaluation. The LC/MS approach has been widely used to structurally characterize mAbs, and recently attempts have been made to obtain comprehensive information on the primary structure and post-translational modifications (PTMs) of mAbs through intact protein analysis. In this study, we performed state-of-the-art LC/MS based intact protein analysis to readily identify and characterize glycoforms of various mAbs. Different glycoforms of mAbs produced in different expression cell lines including CHO, SP2/0 and HEK cells were monitored and compared. In addition, the comparability of protein molecular weight, glycoform pattern, and relative abundances of glycoforms between the commercialized trastuzumab biosimilar and the original product was determined in detail using the given platform. Intact mAb analysis allowed us to gain insight into the overall mAb structure, including the complexity and diversity of glycosylation. Furthermore, our analytical platform with high reproducibility is expected to be widely used for biopharmaceutical characterization required at all stages of drug development and manufacturing.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.7
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• pp.67-78
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• 2021

The COVID-19 pandemic sweeping the world has rendered a large proportion of the workforce unable to commute to work, to mitigate the spread of the virus. This has resulted in both employers and employees seeking alternative work arrangements. Due to the pandemic, most if not all workers experienced work from home Hence work from home has become a policy priority for most governments. Individuals have started to change their behavior to stick to the curfew and rapidly conform to the new way of life. This study is conducted to understand how organizations and people adjust to these developments and challenges. Numerous organizations are changing to the online method of working because of the COVID-19. Because of the continuous adoption of a specific behavior after the COVID-19 pandemic situation ended, employees were expected to continue working from home. To investigate deep into the behavioral consequences of such a pandemic situation, in-depth interviews were conducted in several companies in Saudi Arabia. This study was conducted by extending the Theory of Planned Behavior (TPB) and the theory of reasoned action (TRA) to explore and assess the various factors that determine the continuous adoption intention of work-from-home by the Saudis. The finding shows that the employees' positive attitude, subjective norms, and self-efficacy affect the employees' intention to adopt work from home. The continuous adoption of work from home has been affected by employees' relevant intention and controllability.

• Journal of Sensor Science and Technology
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• v.31 no.1
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• pp.31-35
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• 2022

The efficacy improvement of the light emitting diode (LED) was studied for the realization of small-size, low power consumption, and highly sensitive bio-sensor instrument. The performance of the LED with Mg delta-doping at the interface of AlGaN/GaN super-lattice in p type cladding layer was simulated. The device with Mg delta-doping showed improved current, radiative recombination rate, electroluminescence, and light output power compared to the conventional LED structure. Under the bias condition of 5 V, the improved device exhibited 20.8% increase in the light output power. This is attributed to the increment of hole concentration from stable ionization of Mg in p type cladding layer. This result is expected to be used for the miniaturization, power saving, and sensitivity improvement of the bio-sensor system.

• Journal of Society of Preventive Korean Medicine
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• v.25 no.3
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• pp.73-88
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• 2021

Objectives : The purpose of this study is to explore the experiences of traditional korean medical doctors (TKMD) who have treated victims of sexual violence by collecting their qualitative data that cannot be obtained with statistical data. Methods : In-depth interviews were conducted with semi-structured questionnaires for each of 5 TKMDs who had experiences in treating sexual violence victims. For analysis, the interviews were recorded along with their facial expressions and actions during the interview process, and all collected data were analyzed by colaizzi's method. In each process, a 'phenomenological reduction' was applied. Results : The identity of TKMD's experience of treating sexual violence victims was structured into 25 themes, 9 theme clusters, and 4 categories. The 4 categories included 'Professionalism and sense of efficacy', 'Personal life experiences and mental trauma treatment experiences that are mutually influencing each other', 'Factors needed to increase TKMD's participation in treatment of sexual violence victims', 'Deriving the future strategy of traditional korean medicine'. Conclusions : This study derived the essence and meaning of TKMDs' experiences in treating sexual violence victims, and presented future directions of traditional korean medicine in this field. It is expected that the results of this study would be used as the basis for establishing the traditional korean medical support system for sexual violence victims in the context of the korean medical system.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.30 no.3
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• pp.54-64
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• 2022

Airlines have been introducing self check-in kiosks to reduce check-in time and improve operational efficacy to increase business revenue. The domestic airlines have actively provided kiosks at airports which are expected to reduce their operating costs and enrich their passengers' travel convenience. Based on the above background, the study investigates the factors influencing intention to use the self check-in kiosks by employing the Extended Technology Acceptance Model (ETAM). The study, therefore, designed a research model by reviewing theories and studies on the relationship among information quality, innovativeness, perceived ease of use, perceived usefulness, and intention to use the kiosks. The structural equation model revealed the following. Information quality and innovativeness had a significantly positive influence on perceived ease of use and perceived usefulness; furthermore, perceived ease of use had a significantly positive influence on perceived usefulness. In addition, both perceived ease of use and perceived usefulness had a significantly positive influence on intention to use. The results indicate that the airlines should constantly develop user-friendly contents and design of the self check-in kiosks.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.11
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• pp.4203-4223
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• 2021

Accelerated by the Internet of Things (IoT), the need for further technical innovations and developments within wireless communications beyond the fifth generation (B5G) networks is up-and-coming in the past few years. High altitude platform station (HAPS) communication is expected to achieve such high levels that, with high data transfer rates and low latency, millions of devices and applications can work seamlessly. The HAPS has emerged as an indispensable component of next-generations of wireless networks, which will therefore play an important role in promoting massive IoT interconnectivity with 6G. The performance of communication and key technology mainly depend on the characteristic of channel, thus we propose an efficient Markov chain based channel model, then analyze the HAPS communication system's uplink capability and swing effect through experiments. According to the simulation results, the efficacy of the proposed scheme is proven to meet the requirements of ubiquitous connectivity in future IoT enabled by 6G.

• The Journal of Industrial Distribution & Business
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• v.14 no.2
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• pp.1-9
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• 2023

Purpose: Workers are expected to perform their tasks and explore differences through innovation. Despite managerial coaching growing attention, limited studies offer information on the effects of managerial coaching towards psychological safety and job commitment. There is a limited empirical study examining managerial coaching efficacy. However, practitioners and researchers have emphasized managerial coaching contribution on improvement of subordinates outcomes. This study intend to fill the research gap on literature regarding managerial coaching, job commitment and psychological safety. Research design, data and methodology: The present research has conducted the literature content analysis which is widely used by numerous prior studies that was already proved as a flexible and straightforward methodology. Results: Based on the textual approach in the past and current literature, the results indicated that the managerial coaching effects on workers job commitment and psychological safety which include workers performance and job satisfaction. As a result, the workers are ready to engage their jobs and improve their performance. Conclusions: The current research concluded that the managers must strive to facilitate employees to earn clarity on their responsibilities and goals and feel psychologically empowered. A leader intending to implement managerial coaching must understand their abilities and the consequences of their actions.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.2
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• pp.424-444
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• 2022

In hospitals and pharmacies, the distribution of medicines is an important part. Any mistakes, misses, fake medicines and expired medicines can cause medical accidents. With the widespread application of the Internet of Things technology (IoT), traditional drug distribution methods need to be upgraded. This article proposes a drug distribution management scheme based on the Internet of Things technology. In the production of drugs, a flexible RFID tag was printed on the packaging box, which stored a series of information such as drug name, dosage, raw materials, efficacy, production date, expiration date, and manufacturer. The use of a drug distribution management system combined with RFID readers can identify drug information and effectively prevent the occurrence of erroneous, missed, counterfeit, and expired drugs. It can also improve management efficiency, reduce management costs, and control management risks. Through the circuit design and software system development, the test results show that this solution is effective and feasible, the proposed method can achieve the expected results.

• Biomedical Science Letters
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• v.28 no.3
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• pp.206-210
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• 2022

Calystegia dahurica (Herb.) Choisy is a natural product that has not been studied for efficacy or active ingredients. The purpose of this study is to investigate the activation effect of natural killer cells using a natural extract composition based on Calystegia dahurica (Herb.) Choisy extract (CDCE). We evaluated the activity of natural killer cells in natural products using PBMCs from healthy participants. All natural products were extracted with 50% ethanol. Based on the results of the cell viability assay, PBMCs of healthy participants were treated with extracts at various concentrations. Then, analysis was performed using flow cytometry to measure the cd107a surface expression of natural killer cells. As a result, treatment with a single extract of PBMCs increased the expression of cd107a in a concentration-dependent. Furthermore, it was confirmed that the treatment of the extract composition showed the highest expression of cd107a. In conclusion, it is expected that the extract composition containing CDCE according to this study can be used for prevention or treatment of cancer cells, tumor cells, and immune diseases.