• 한국조명전기설비학회지:조명전기설비
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• 제13권2호
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• pp.171-171
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• 1999

In case of field weakening region torque is directly affected by flux. In this region the flux reference is decreased inversely proportional to the rotor speed. As the flux is decreased the magnetizing inductance is normally increased. The increased magnetizing inductance limited voltage for controlling current. In this paper, measuring q axis voltage in field weakening region magnetizing inductance in flux calculating can be readjusted. Computer simulation and experiment results demonstrate the efficacy of the proposed method. Proposed algorithm is expected to the application of the adjustable drive system in the spinning and weaving field.

• 접착 및 계면
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• 제21권1호
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• pp.6-13
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• 2020

The objective of the current study is to characterize the long-term stability and efficacy of a structural adhesive assembly under static load. An apparatus was designed to be used in the Instron tensile test machine that would allow for real time modeling of the failure characteristics of an assembly utilizing a moisture- cure adhesive which was bonded to concrete. A regression model was developed that followed a linear - natural log function which was used to predict the expected life of the assembly. Evaluations at different curing times confirmed the structure was more robust with longer cure durations prior to loading. Finally, the results show that under the conditions the assembly was tested, there was only a small amount of inelastic creep and the regression models demonstrated the potential for a stable structure lasting several decades.

• Korean Journal of Acupuncture
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• 제25권4호
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• pp.147-166
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• 2008

Objective : This study is achieved to know the way that we can use metabolomics for the scientific research of Korean medicine. Results : We elucidate that metabolomics can be contributed to four ways for objectification of Korean medicine 1. Diagnosis of BeunJungLonChi(辯證論治). 2. Application toward Personalized medicine. 3. Quantification of Herbal medicine. 4. Evaluation of efficacy/safety for Korean medicine formulation Conclusion : Metabolomics opens up a new opportunity to reinvestigate Korean medicine from holistic perspective. Furthermore, Metabolomics is expected to provide effective method in research of acupuncture and meridian.

• 한국군사과학기술학회지
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• 제21권2호
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• pp.204-210
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• 2018

As the 4th industrial revolution and artificial intelligence technology develop, it is expected that there will be a revolutionary changes in the security robot. However, artificial intelligence system requires enormous hardwares for tremendous computing loads, and there are many challenges that need to be addressed more technologically. This paper introduces precise tracking control technique of autonomous system that need to move repetitive paths for security purpose. The input feedforward signal is generated by using the inverse based iterative learning control theory for the 2 input 2 output nonminimum-phase system which was difficult to overcome by the conventional feedback control system. The simulation results of the input signal generation and precision tracking of given path corresponding to the repetition rate of extreme, such as bandwidth of the system, shows the efficacy of suggested techniques and possibility to be used in military security purposes.

• Biomolecules & Therapeutics
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• 제2권4호
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• pp.322-325
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• 1994

To optimize the immunological efficacy of CFC-101, an outer-membrane protein vaccine purified from relatively less pathogenic 4 different Pseudomonas aeruginosa strains, we investigated to establish its dose, administration route, interval and frequency of vaccination in mice. As expected, the 4 CFC-101 producing strains were less pathogenic than the challenging organism, P. aeruginosa GN11189. CFC-101 completely protected the death caused by P. aeruginosa at above 0.05 mg/kg vaccinized by 3 times with 7-day intervals. At the optimally effective dose of 0.2 mg/kg of CFC-101, at least 3 immunizations were necessary for complete protection against P. aeruginosa-induced death. If immunized 3 times, the immunization interval could be shortened up to 2 days to acquire the best protection against P. aeruginosa. CFC-101 was effective either by intraperitoneal, subcutaneous or intramuscular but not by oral administration. The present results show that the newly developed Pseudomonas vaccine, CFC-101, is highly effective for the protection from death caused by pseudomonal infections.

• Journal of Yeungnam Medical Science
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• 제26권1호
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• pp.1-14
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• 2009

Human bone marrow-derived mesenchymal stem cells (MSCs) are a rare population of undifferentiated cells that have the capacity of self renewal and the ability to differentiate into mesodermal phenotypes, including osteocytes, chondrocytes, and adipocytes in vitro. Recently, MSCs have been shown to reside within the connective tissue of most organs, and their surface phenotype has been well analyzed. Many reports showed that transplanted MSCs enhanced regeneration as well as functional improvement of damaged organs and tissues. The wide differentiation plasticity of MSCs was expected to contribute to their demonstrated efficacy in a wide variety of experimental animal models and in human clinical trials. However, new findings suggest that the ability of MSCs to alter the tissue microenvironment via secretion of soluble factors may contribute more significantly than their capacity for differentiation in tissue repair. This review describes what is known about the cellular characteristics and differentiation potential of MSCs, which represent a promising stem cell population for further applications in regenerative medicine.

• 대한화학회지
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• 제63권4호
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• pp.253-259
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• 2019

5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR), a structural analog of adenosine monophosphate (AMP), promotes oxidative remodeling in muscle cells. AICAR activates AMP-dependent protein kinase (AMPK), thus increasing lipid metabolism, respiration, and mitochondrial counts. This process is called oxidative remodeling, which enhances the physical endurance of mice. To test this drug on an invertebrate that is genetically similar to humans, we used the small water crustacean Daphnia magna, which is sensitive to changes in water conditions. We tested the effects of pH on the efficacy of AICAR using two methods. One method measured oxygen consumption of Daphnia in oxygen chambers. The other method determined lipid levels of Daphnia through fluorescent tagging of lipids. The results showed that when exposed to AICAR at pH 6.58, D. magna consumed more oxygen and had lower overall levels of lipids, which is consistent with the expected effects of AICAR, such as increased respiration and lipid metabolism.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.235.1-235.1
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• 2003

With an aim of obtaining high efficacy in cartilage regeneration, implantable polymeric rods were fabricated. These rod-type matrices were anticipated to perform structural tissue supporting activity and enhance extracellular matrix (ECM) formation by releasing specific agent, DHEA-S, in controlled manner. It is expected that application for the drilling operation on the articular cartilage of OA patients as the implants may promote regeneration of their cartilage. Osteoarthritis (OA) is a degenerative joint disease characterized by progressive loss of articular cartilage, subchondral bone remodeling, spur formation, and synovial inflammation. (omitted)

• 대한의생명과학회지
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• 제27권4호
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• pp.231-238
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• 2021

Several structural proteins present in keratinocytes of the skin are known to play an important role in the formation of epidermal tissue and barrier function, and the absence of structural proteins in keratinocytes causes various skin diseases. In this study, 42 types of tetrapeptides derived from the sequence of Loricrin, a kind of terminally differentiating structural protein, were synthesized, and skin anti-aging properties were measured by measuring the elastase inhibition, proliferation of skin cells. The anti-aging efficacy was verified and, based on this, it succeeded in selecting one of the most excellent peptides. It is expected that the selected tetrapeptide can be used as a raw material for various cosmetics and quasi-drugs based on anti-aging and skin cell proliferation effects.

• 항공우주의학회지
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• 제31권1호
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• pp.13-16
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• 2021

The coronavirus disease-19 (COVID-19) vaccine is expected to play an important role in stopping the pandemic. Studies show that COVID-19 vaccines are effective at keeping you from getting COVID-19. Getting a COVID-19 vaccine will also help keep you from getting seriously ill even if you do get COVID-19. Efforts to find an effective vaccine against severe acute respiratory syndrome coronavirus 2 have progressed unprecedentedly through active support from public research grants and private-public partnership programs. Clinical studies have been actively conducted, and some vaccines are being vaccinated with approval for urgent use. The WHO has approved and supplied the Pfizer-BioNTech COVID-19 vaccine and the Oxford-AstraZeneca COVID-19 vaccine. In Korea, the Oxford-AstraZeneca vaccine was approved for urgent use, and vaccination began on February 26, 2021. In this paper, the efficacy and side effects of each vaccines and the effect on pilots and air traffic controllers related to COVID-19 vaccination were investigated in terms of aviation medicine.