• Genomics & Informatics
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• v.12 no.4
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• pp.187-194
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• 2014

Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. As a result, we could identify 2 single nucleotide polymorphisms (SNPs) with genome-wide significance level p-values (< $5{\times}10^{-8}$), 8 SNPs with genome-wide suggestive p-values ($5{\times}10^{-8}{\leq}$ p < $1{\times}10^{-5}$), and 2 SNPs of more functional variants with borderline p-values ($5{\times}10^{-5}{\leq}$ p < $1{\times}10^{-4}$). On the other hand, the multiple correction criteria of conventional GWASs exclude false-positive loci, but simultaneously, they discard many true-positive loci. To reconsider the discarded true-positive loci, we attempted to include the functional variants (nonsynonymous SNPs [nsSNPs] and expression quantitative trait loci [eQTL]) among the top 5,000 SNPs based on the proportion of phenotypic variance explained by genotypic variance. In total, 159 eQTLs and 18 nsSNPs were presented in the top 5,000 SNPs. Although they should be replicated in other independent populations, 6 eQTLs and 2 nsSNP loci were located in the molecular pathways of LPL, APOA5, and CHRM2, which were the significant or suggestive loci in the METS GWAS. Conclusively, our approach using the conventional GWAS, reconsidering functional variants and pathway-based interpretation, suggests a useful method to understand the GWAS results of complex traits and can be expanded in other genomewide association studies.

• Current Optics and Photonics
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• v.1 no.5
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• pp.474-490
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• 2017

Since the recent slowdown in the smartphone market, studies for wearable devices are briskly being carried out to find new markets, such as virtual reality devices. In this paper, a head-mounted display (HMD) which provides expanded virtual images before human eyes by enlarging images of a small display was designed, and the tolerance analysis method for a focus-adjustable HMD based on afocal optical systems was studied. There are two types of HMDs: a see-through type that allows the user to view the surroundings, and a see-close type where the user can only view the display screen; the former is used in this study. While designing the system, we allowed a lens within the system to be shifted to adjust its focus from +1 to -4 D (diopters). The yield of the designed systems was calculated by taking the worst-case scenario of a uniform distribution into account. Additionally, a longitudinal aberration was used rather than MTF for the tolerance analysis with respect to system performance. The sensitivity of the designed system was calculated by assigning a certain tolerance, and the focus lens shift was calculated to adjust the image surface variations resulting from the tolerance. The smaller the tolerance, the more expensive the unit price of the products. Very small tolerances may even be impossible to fabricate. Considering this, the appropriate tolerance was assigned; the maximum shift of the focus lens in which the image surface can be adjusted was obtained to find the changes in aberration and a good yield.

• Journal of the Korean Institute of Telematics and Electronics
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• v.22 no.6
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• pp.114-123
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• 1985

This is the second part of the four-part paper describing the development of a packet-switched computer network named the cORNET In this paper, following the first par paper that describes the concepts of the KORNET and the development of the network management center (NMC), wc present the design of the KORNET and the development of the network node processor (NNP) The initial configuration of the KORNET consists of three NNP's and one NMC. We have developed each NNP as a microprocessor-based (Mc68000) multiprocessor system, and implemented the NMC using a super-mini computer (Mv/8000) For the KORNET we use the virtual circuit (VC) method as the packet service strategy and the distributed adaptive routing algorithm to adapt efficiently the variation of node and link status. Also, we use a dynamic buffer management algorithm for efficient storage management. Thc hardware of the NNP system has been designed with emphasis on modularity so that it may be expanded esily . Also, the software of the NNP system has been developed according to the CCITT recommendations X.25, X.3, X.28 and X.29.

• The Journal of Bigdata
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• v.5 no.1
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• pp.41-54
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• 2020

With the recent expansion of Internet channels and the development of financial technology and information and communication technology, direct overseas purchases have expanded. Although direct overseas purchases dominate consumers in terms of price and scarcity by providing relatively low-priced products and products that are difficult to obtain in Korea, there is a higher chance of consumer dissatisfaction in terms of delivery, product, A/S and refund than domestic purchases. Therefore, this study analyzed consumer dissatisfaction caused by active overseas direct purchase and studied ways to improve problems with overseas direct purchase. As a research method, Several statistical data were collected from the Korea Consumer Agency(KCA), the Korea Customs Service(KCS) and the Korea International Trade Association(KITA) and analyzed using the Exploratory Data Analysis Technique (EDA). The analysis confirmed that consumers were not well aware of information about direct overseas purchases and that the type or degree of consumer complaints varied depending on the type of purchase. Therefore, this study suggests a direction for the revitalization of overseas direct purchases by using EDA to identify the overall status of overseas direct purchases and consumer dissatisfaction and to improve them.

• Journal of dental hygiene science
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• v.20 no.1
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• pp.16-24
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• 2020

Background: Dental treatment has shifted to the center of the community, and the public policy of the country has expanded to support the vulnerable classes such as the disabled. The dental profession needs education regarding oral health services for persons with disabilities, and it is necessary to derive the competencies for this. Therefore, we conducted this study to derive the normative ability to understand the role of a dental hygienist in the oral health service for persons with disabilities and improvement plans for education. Methods: We conducted a qualitative analysis for deriving competencies by analyzing the data collected through in-depth interviews with experts in order to obtain abilities through practical experience. Based on the competency criterion, relevant competency in the interview response was derived using the priori method, and it was confirmed whether the derived ability matched the ability determined by the respondent. Results: The professional conduct competencies of dental hygienists, devised by the Korean Association of Dental Hygiene, consists of professional behavior, ethical decision-making, self-assessment skills, lifelong learning, and accumulated evidence. Also, core competencies of the American Dental Education Association competencies for dental hygienist classification such as ethics, responsibility for professional actions, and critical thinking skills were used as the criterion. The dental hygienist's abilities needed for oral health care for people with disabilities, especially in the detailed abilities to fulfill these social needs, were clarified. Conclusion: To activate oral health care for people with disabilities, it is necessary for dental hygienists to fulfill their appropriate roles, and for this purpose, competency-based curriculum restructuring is indispensable. A social safety net for improving the oral health of people with disabilities can be secured by improving the required skills-based education system of dental hygienists and strengthening the related infrastructure.

• Journal of Digital Convergence
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• v.14 no.7
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• pp.373-383
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• 2016

With mobile-epoch and emerging of Fin-tech, Bio-recognition technology utilizing bio-information in secure method has spread. Specially, In order to change convenient payment services and transportation cards, the combination of biometrics and mobile services are being expanded. The basic concept of authentication such as access control, IA&A, OpenID, OAuth 1.0a, SSO, and Biometrics techniques are investigated, and the protocol stack for security API platform, FIDO, SCIM, OAuth 2.0, JSON Identity Suite, Keystone of OpenStack, Cloud-based SSO, and AIM Agent are described detailed in aspect of application of AIM. The authentication technology in domestic and foreign will accelerate technology development and research of standardization centered in the federated FIDO Universal Authentication Framework(UAF) and Universal 2 Factor Framework(U2F). To accommodate the changing needs of the social computing paradigm recently in this paper, the trends of various authentication technology, and design and function of AIM framework was defined.

• Journal of Digital Convergence
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• v.18 no.4
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• pp.433-438
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• 2020

With the rapid development of media environment and contents production technology, the era of multi-platform convergence transmedia has emerged, and communication method through trans media contents has attracted attention. Transmedia content refers to the concept of translating individual content into multi-platforms, which creates an expanded worldview of convergence. In addition, the interaction generated in this process is very important and difficult to control in the progress of the content. In this paper, we focused on the combination of transmedia content and gamification concept as a solution, and based on the 'MDA framework' which is a theoretical system of analysis and approach for implementing game design, We looked at the structure. It is expected that a review of the fundamental game design structure, which establishes a prediction system of value and fun experiences through the balance of technology and emotions, will be helpful as a basis for designing trans media contents.

• Journal of Digital Convergence
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• v.18 no.4
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• pp.381-388
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• 2020

Based on local viewers' awareness of locality and consideration of desired local broadcasting service, this study explored the direction of service policy and specific service strategy of local broadcasting. The research method is a secondary analysis using three regional audience surveys and in-depth interview data conducted by KBS. For local audience, the concept of localism is being narrowed down to the city/county/district where they live. In order to reinforce the identity of local broadcasting and improve local broadcasting services, first, the function and role should be expanded to the local mega platform. Second, regional programs such as in-depth coverage and discussion of local issues should be strengthened. Third, in order to communicate with local audience, viewer analysis ability and communication education of local broadcasting members are required. Fourth, it is necessary to create an ecosystem in which local people participate as producers of local broadcasting.

• The Research Journal of the Costume Culture
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• v.16 no.2
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• pp.382-396
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• 2008

The purpose of this study is to analyze the transition of glamour style expressed in modern fashion throughout the history. The glamour style in modern fashion was categorized into five periods which are Hollywood glamour(H), Feminine glamour(F), Rich glamour(R), Decadent glamour(D), and Trash glamour(T). These categories were analyzed and compared in the viewpoint of aesthetic values deduced on the previous study. As a method of analysis, literature study and case study through the publications in aesthetics, history and preceding theses were used. The results of analysis are: Ostentatious luxury was suggested by extravagance of the movie star in H, the splendid American lifestyle in F, conspicuous consumption in R, fin de siecle bad taste in D and self-assured exposure in T. Mysterious idolatry was studied as exaggerated goddesshood of the movie star in H. It was expanded to celebrities including fashion models, television actresses, pop singers and young couture designers in the other periods. Artificial sensuality was originated from the femme fatale image of the courtesan as well as the traditional femininity of Victorian era in H. It was developed through exaggerated hourglass silhouette of the wife dressing in F. But an aggressiveness in R, a hyper-sexual femme fatale in D, an independent and defiant image of the showgirl in T were observed. Playful queerness stood out clearly by the fin de siecle phenomena. Though it was embodied in sexual perversive subculture, it emerged as hi fashion by young designers in the late R and became a crucial aesthetic value throughout D and T. It is more connected with the origins of glamour which arouses sexual ambiguity, crudity, aggressiveness and death. The continuity and discontinuity of the glamour style based on the theory of 'linked solution' were also analyzed.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2004.03a
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• pp.165-172
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• 2004

LE-7A is the main engine of the H-IIA launch vehicle. Under its development, the nozzle suffered from two troubles during startup and shutdown transients of the engine. One is a large side load, which damages the actuator of the nozzle, and the other is damage on regenerative cooling tubes due to high heat load. It has been considered that these problems are caused by a peculiar separation pattern called Restricted Shock Separation (RSS). RSS is observed in several rocket nozzles, for example, LE-7A nozzle, Vulcain nozzle and so on. Their contours are not conventional truncated perfect (TP) nozzle - LE-7A nozzle is a compressed truncated perfect (CTP) nozzle and Vulcain nozzle is a thrust optimized (TO) nozzle. Although it is believed that the occurrence of RSS is affected by the nozzle contour, the mechanisms are not clarified sufficiently yet. In the present paper, a parametric numerical study is carried out to investigate the mechanisms of the occurrence of RSS in CTP nozzles during startup transient. The results show that RSS is caused by the adverse pressure gradient downstream of the Mach disk. The adverse pressure gradient is caused by the interaction of the pressure wave and Mach disk. The method to avoid the occurrence of RSS is also examined. A small step inside the nozzle affects the position of the separation point and prevents RSS. The result shows that the possibility that RSS can be suppressed by controlling the position of the separation point.