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Effect of Physiologically Active Compounds Isolated from Platycodon grandiflorum on Streptozotocin-Induced Diabetic Rats (장생도라지 생리활성물질이 Streptozotocin으로 유발된 당뇨쥐에 미치는 영향)

  • 서종권;정영철;전성식;이영우;이수정;손미예;성낙주
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.6
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    • pp.981-986
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    • 2004
  • This study were investigated the effects of physiologically active compounds isolated from Platycodon grandiflorum on streptozotocin-induced diabetic rats. The experimental groups were divided into six groups, normal, diabetic control (CM), and four experimental groups (inulin (IN), inulin + saponin (IS), oligosaccharide (OS), and total extract group (WE)). The rats have free access to water and diet. Experimental groups were administered orally with inulin (630 mg/mL), inulin (630 mg/mL) + saponin (25.2 mg/mL), oligosaccharide (367.5 mg/mL), and total extract (225 mg/mL) into the diabetic rats for 5 weeks after STZ injection; The levels of fasting blood glucose in diabetic control increased by 10.0% for 5 weeks, but the level of blood glucose in inulin and total extract groups decreased by 21.3% and 21.2%, respectively. The concentrations of total cholesterol and triglyceride in serum of diabetic rats fed physiologically activity compounds were lower than those in diabetic control rats. HDL-cholesterol was similar among all the groups. Weights of testicle and heart were lighter, while weight of kidney was significantly increased in diabetic groups than normal group. The concentrations of serum protein insulin and albumin in diabetic groups were significantly decreased compared with those of the normal group. Urinary glucose excretion was decreased in inulin group than other diabetic groups.

The Effects of Levan on Blood Lipids and the Absorption of Calcium in Rats Fed a Low Calcium Diet (레반의 혈장지질 감소와 칼슘흡수율 증가 효과)

  • No, Jung-Ran;Park, Sun-Young;Kim, Mi-Kyoung;Jo, Han-Young;Lee, In-Young;Ly, Sun-Yung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.1
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    • pp.51-57
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    • 2007
  • Levan, the fructose polymer is an indigestible carbohydrate regularly consumed by humans. Its physiological functions, in terms of hypocholesterolemic effect and calcium metabolism, have not been well documented. The objective of this study was to investigate the effects of levan on blood lipids and the calcium absorption ratio in rats fed a 0.1% low calcium diet. Thirty rats were divided into three groups and fed a 0.1% low calcium diet (control) or low calcium diets containing either 2.5% levan or 5% levan for eight weeks. The blood lipid and biomarkers relevant to Ca metabolism (urinary Ca and hydroxyproline), the femoral weight and the Ca contents were determined. The body weight gains were lower in the 5% levan group than the control group. Plasma concentrations of triacylglycerol and LDL-cholesterol decreased in the 5% levan group, compared to the control group, but the atherogenic indice were not affected. Blood alkaline phosphatase activity, Ca and urinary hydroxyproline excretion levels were not different in the three groups. The net calcium absorption in rats fed a 5% levan diet was greater than rats fed the control diet, while the femoral weights and Ca contents were not significantly different in the three groups. We concluded that a 5% levan diet could both enhance the calcium absorption and improve the lipid profiles in rats fed a low calcium diet.

Partial replacement of soybean meal with different protein sources in piglet feed during the nursery phase

  • Genova, Jansller Luiz;Carvalho, Paulo Levi de Oliveira;Oliveira, Newton Tavares Escocard de;Oliveira, Aparecida da Costa;Gois, Franz Dias;Castro, Davi Elias de Sa e;Souza, Fabio Nicory Costa;Trautenmuller, Heloise;Santos, Liliana Bury de Azevedo dos;Leal, Isabela Ferreira
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.11
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    • pp.1725-1733
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    • 2019
  • Objective: Evaluate the partial replacement of soybean meal with different protein sources in piglet feed during the nursery phase in terms of digestibility of feed, nitrogen balance, growth performance and blood parameters. Methods: Experiment I involved 24 crossbred entire male pigs with an initial body weight (BW) of $18.28{\pm}0.7kg$ and used a randomized complete block design consisting of 3 treatments (fish meal, FM; soybean protein concentrate, SPC; and soybean meal, SBM) and 8 replicates, with 1 pig per experimental unit. Experiment II involved 1,843 crossbred male and female pigs with an initial BW of $6.79{\pm}0.90kg$ and was based on a completely randomized design with a $2{\times}3$ factorial arrangement (2 sexes and 3 protein sources) and 13 replicates. Results: The results of Exp. I indicate effects (p<0.05) of dietary protein sources on digestible protein (FM, 17.84%; SPC, 16.72%, and SBM, 18.13%) and on total nitrogen excretion (TNE, $g/kg\;BW^{0.75}/d$) in which pigs fed with SBM-based feed had TNE values that were 5.36% and 3.72% greater than SPC and FM, respectively. In the Exp. II, there was difference (p<0.01) between sexes in the pre-starter I and starter phases, and total period in average daily feed intake (ADFI), which were greater in females, and between the protein sources, ADFI, final weight and daily weight gain. For urea in the pre-starter II and starter phases and glucose in the pre-starter II phase, there was a difference (p<0.05) between protein sources and between sexes, in starter phase in urea concentrations (females: 57.11 mg/dL and males: 50.60 mg/dL). Conclusion: The use of SBM as only protein source influences larger TNE ($g/kg\;BW^{0.75}/d$), reduces the growth performance of piglets and increases plasma urea concentrations in prestarter II phase.

Development of a Groundwater Quality Sampling Method for Livestock Excreta Survey (가축분뇨실태조사를 위한 지하수 오염현황조사 지점 선정 방법 개발)

  • Kim, Deok-Woo;Ryu, Hong-Duck;Baek, Unil;Kim, Sunjung;Shin, Dong Seok;Lee, Jae Gwan;Chung, Eu Gene
    • Journal of Environmental Science International
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    • v.28 no.1
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    • pp.37-54
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    • 2019
  • The groundwater quality through livestock excreta survey based on "Act of the management and use of livestock excreta" was investigated by selecting sampling sites within 1 km of the farmland without considering hydrogeological units. However, these sites can be affected by various pollution sources such as chemical fertilizers and livestock excretions. Additionally, the effects of pollution sources on groundwater quality in the sites cannot be clearly distinguished from naturally occurring backgrounds. In this study, a method was developed to select the sampling sites for groundwater quality through livestock excreta survey in order to understand the effects of pollution sources especially livestock excreta. First, the concentrations of nitrate within the radius of 200 m, 300 m, 500 m and 750 m, respectively, from the farms regarded as pollution sources in hydrogeological units were compared in 2016-2017. All the nitrate concentrations at 200 - 500 m from the farms exceeded a background concentration, 13.3 mg/L. Those at 750 m and the background concentrations measured by the Ministry of Environment were comparable. Therefore, the appropriate radius was suggested as 500 m for livestock excretions survey. In this study, the areas within 500 m from the farms could be considered under the influence of livestock excretions, while those beyond 500 from the pollution sources as background in hydrogeological units. The developed method was validated by applying it to the sites selected based on both administrative divisions and watersheds for livestock excretion survey. The average densities for the developed method were 0.82 and 0.39 points/km2, respectively, which were considered as appropriate levels according to those of the European Environmental Agency.

A Comparative study on Perceived Importance and Frequency of Basic Nursing Performance ability of Comprehensive Nursing Care Service Wards versus General Wards (간호·간병 통합서비스 병동과 일반병동 간호사의 기본간호술 수행 빈도 및 중요성 인식 비교)

  • Kim, Soon-Ok
    • Journal of Digital Convergence
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    • v.16 no.12
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    • pp.541-553
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    • 2018
  • The purpose of this study was to analyze the differences in the frequency and importance of basic nursing practice between comprehensive nursing care service wards and general wards and to provide basic data for the efficient of services. The subjects of this study were 99 comprehensive nursing care service and 90 general wards. Data were collected from February 1 to 28, 2018 and analyzed using a t-test, one-way ANOVA, Pearson's correlation coefficient, Scheffe test. The results showed that the frequency of basic nursing practice was higher by 2.43, and there were significant differences in personal hygiene, nutrition and excretion, exercise & activity. The recognition of the importance of basic nursing was high in both groups, but comprehensive nursing care service wards were slightly higher at 4.24 points. However, as the frequency of practice is lower than the recognition of the importance of basic nursing, a method to increase the frequency of practice is necessary. These results suggest that comprehensive nursing care service wards should provide appropriate nursing staff and system development so the nurses can provide care service as professionals.

Biological Response of Resistant Genes to Korean Brown Planthopper, Nilaparvata lugens Stål (벼멸구 저항성 유전자에 대한 국내 벼멸구의 생물적 반응 연구)

  • Choi, Nak Jung;Kim, Gwang-Ho;Baik, Chai-Hun;Lee, Bong-Choon
    • Journal of Life Science
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    • v.29 no.2
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    • pp.202-208
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    • 2019
  • Brown planthopper (BPH), Nilaparvata lugens Stål (Hemiptera: Delphacidae), is one of the most important migratory pests damaging rice in Korea. It invades annually from tropical and subtropical areas via continental air streams. It is necessary to determine the resistance levels of rice varieties in order to control efficiency. The honeydew excretion, development, and reproduction of the migratory BPH were studied by region in a laboratory at $25{\pm}2^{\circ}C$ and $65{\pm}5%\;RH$ and a 16L: 8D photoperiodism conducted on three BPH resistant genes: Bph1, Bph2, and Bph18. The information obtained was reported using the jackknife method, and we created life table statistics accordingly. The feeding amount of Bph1 resistant gene was lower than that of resistant genes. The developmental periods of immature stages ranged from $13.7{\pm}0.10d$ on Bph2 (Namhae, 2015) to $18.5{\pm}1.06d$ on Bph2 (Sacheon, 2016). Reproductive period and female longevity were longest on the non-resistant genes, Bph2 and Bph18 (except 1980s), and the highest fecundity of N. lugens was observed on the two BPH resistant genes. Highest net reproductive rates ($R_0$) were calculated on Bph2 by region. Intrinsic rates of population increase ($r_m$) showed a difference in resistant genes by region. These population parameters showed that migratory regions and biological characteristics of N. lugens vary annually.

Potential to mitigate ammonia emission from slurry by increasing dietary fermentable fiber through inclusion of tropical byproducts in practical diets for growing pigs

  • Nguyen, Quan Hai;Le, Phung Dinh;Chim, Channy;Le, Ngoan Duc;Fievez, Veerle
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.4
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    • pp.574-584
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    • 2019
  • Objective: Research was conducted to test the effect of including fiber-rich feedstuffs in practical pig diets on nutrient digestibility, nitrogen balance and ammonia emissions from slurry. Methods: Three Vietnamese fiber sources were screened, namely cassava leaf meal (CL), cassava root residue (CR), and tofu by-product (TF). Accordingly, a control diet (Con) with 10% of dietary non-starch polysaccharides (NSP) and three test diets including one of the three fiber-rich feedstuffs to reach 15% of NSP were formulated. All formulated diets had the same level of crude protein (CP), in vitro ileal protein digestible and metabolisable energy, whereas the in vitro hindgut volatile fatty acid (VFA) production of the test diets was 12% to 20% higher than the control diet. Forty growing barrows with initial body weight at $28.6{\pm}1.93kg$ ($mean{\pm}standard$ deviation) were allocated to the four treatments. When pigs reached about 50 kg of body weight, four pigs from each treatment were used for a nitrogen balance trial and ammonia emission assessment, the remaining six pigs continued the second period of the feeding trial. Results: The TF treatment increased fecal VFA by 33% as compared with the control treatment (p = 0.07), suggesting stimulation of the hindgut fermentation. However, urinary N was not significantly reduced or shifted to fecal N, nor was slurry pH decreased. Accordingly, ammonia emissions were not mitigated. CR and CL treatments failed to enhance in vivo hindgut fermentation, as assessed by fecal VFA and purine bases. On the contrary, the reduction of CP digestibility in the CL treatment enhanced ammonia emissions from slurry. Conclusion: Dietary inclusion of cassava and tofu byproducts through an increase of dietary NSP from 10% to 15% might stimulate fecal VFA excretion but this does not guarantee a reduction in ammonia emissions from slurry, while its interaction with protein digestibility even might enhance enhanced ammonia emission.

In-feed organic and inorganic manganese supplementation on broiler performance and physiological responses

  • de Carvalho, Bruno Reis;Ferreira Junior, Helvio da Cruz;Viana, Gabriel da Silva;Alves, Warley Junior;Muniz, Jorge Cunha Lima;Rostagno, Horacio Santiago;Pettigrew, James Eugene;Hannas, Melissa Izabel
    • Animal Bioscience
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    • v.34 no.11
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    • pp.1811-1821
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    • 2021
  • Objective: A trial was conducted to investigate the effects of supplemental levels of Mn provided by organic and inorganic trace mineral supplements on growth, tissue mineralization, mineral balance, and antioxidant status of growing broiler chicks. Methods: A total of 500 male chicks (8-d-old) were used in 10-day feeding trial, with 10 treatments and 10 replicates of 5 chicks per treatment. A 2×5 factorial design was used where supplemental Mn levels (0, 25, 50, 75, and 100 mg Mn/kg diet) were provided as MnSO4·H2O or MnPro. When Mn was supplied as MnPro, supplements of zinc, copper, iron, and selenium were supplied as organic minerals, whereas in MnSO4·H2O supplemented diets, inorganic salts were used as sources of other trace minerals. Performance data were fitted to a linearbroken line regression model to estimate the optimal supplemental Mn levels. Results: Manganese supplementation improved body weight, average daily gain (ADG) and feed conversion ratio (FCR) compared with chicks fed diets not supplemented with Mn. Manganese in liver, breast muscle, and tibia were greatest at 50, 75, and 100 mg supplemental Mn/kg diet, respectively. Higher activities of glutathione peroxidase and superoxide dismutase (total-SOD) were found in both liver and breast muscle of chicks fed diets supplemented with inorganic minerals. In chicks fed MnSO4·H2O, ADG, FCR, Mn balance, and concentration in liver were optimized at 59.8, 74.3, 20.6, and 43.1 mg supplemental Mn/kg diet, respectively. In MnPro fed chicks, ADG, FCR, Mn balance, and concentration in liver and breast were optimized at 20.6, 38.0, 16.6, 33.5, and 62.3 mg supplemental Mn/kg, respectively. Conclusion: Lower levels of organic Mn were required by growing chicks for performance optimization compared to inorganic Mn. Based on the FCR, the ideal supplemental levels of organic and inorganic Mn in chick feeds were 38.0 and 74.3 mg Mn/kg diet, respectively.

Partial or complete replacement of fishmeal with fermented soybean meal on growth performance, fecal composition, and meat quality in broilers

  • Premathilaka, Kumudu Thakshila;Nawarathne, Shan Randima;Nambapana, Maleeka Nadeemale;Macelline, Shemil Priyan;Wickramasuriya, Samiru Sudharaka;Ang, Li;Jayasena, Dinesh Darshaka;Heo, Jung Min
    • Journal of Animal Science and Technology
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    • v.62 no.6
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    • pp.824-839
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    • 2020
  • The current study was aimed to examine the effect of partial or complete replacement of fishmeal (FM) with fermented soybean meal (FSBM) on growth performance, fecal composition, and meat quality in broiler chickens. A total number of 240 one-day-old broiler chicks were randomly allotted into four dietary treatments with six replications and ten birds per one pen. Dietary treatments were followed as; 1) Diet incorporated with 4% FM without FSBM (Control), 2) Diet incorporated with 3% FM and 2% FSBM (FSBM2), 3) Diet incorporated with 2% FM and 3% FSBM (FSBM3) and 4) Diet incorporated with 4% FSBM without FM (FSBM4). Body weight and feed intake were recorded weekly for 35 days of the experimental period. Moreover, fecal samples were collected to evaluate moisture, ash, nitrogen, calcium and phosphorus content on day 21 post-hatch. On day 35, two birds were sacrificed from each pen to measure meat quality parameters and visceral organ weights. Results revealed that, no dietary treatment effect (p > 0.05) was observed either in both body weight or average daily gain of broilers within the entire experimental period while broilers fed FSBM2 increased (p < 0.05) average daily feed intake by 10.07% whereas FSBM4 improved (p < 0.05) feed efficiency ratio by 8.45% compared to birds fed other dietary treatments on day 7 post-hatch. Besides, birds fed FSBM3 obtained the improved (p < 0.05) feed conversion ratio over the birds fed control diet by 7.51% from hatch to day 35 post-hatch (1.60 vs. 1.73). Nevertheless, no difference (p > 0.05) was detected on visceral organ weight, proximate composition and physicochemical characteristics of meat while broilers offered FSBM4 obtained the lowest (p < 0.05) calcium and phosphorous in faces (2.27% and 1.21% respectively) over those offered control feed and other FSBM treatments. In conclusion, FSBM would be a better replacement for ousting FM partially or completely in broiler diet as it did not impair the growth performance and meat quality while reducing the calcium and phosphorous excretion in broilers for 35 days post-hatch.

A Study on the Use of Cosmetics by Male Consumers in South Korea, China, and Japan and the Direction for Development (한국, 중국, 일본 남성 소비자의 화장품 사용 실태와 발전방향에 대한 연구)

  • Kim, Kyoung-Bin;Ju, Hyun-Young;Song, Yu-Xin;Zhang, Jia-Yu;Kim, Gyu-Ri
    • Journal of Convergence for Information Technology
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    • v.12 no.4
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    • pp.303-315
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    • 2022
  • This study compared and analyzed Japan and China, two major competitors to Korea, in the male cosmetics market, which has been shifted dramatically by the outbreak of COVID-19, with implications for the ASEAN market in mind. Questionnaire copies collected from 300 men in Generation MZ living in Korea, China, and Japan were used for analysis, and SPSS 21.0 was used to conduct a statistical analysis of the collected questionnaires. The following are this study's results: First, this study identified their purchase behaviors. The average amount of money the male respondents spent on buying cosmetics was below KRW 30,000 in Korea, China, and Japan. Functionality and texture ranked as top factors contributing to cosmetics purchases in all the three countries. Second, with regard to brands preferred by the respondents, Korea and China were open to foreign brands, while Japan mostly preferred its domestic brands. Functionality and texture ranked as top factors contributing to cosmetics purchase in all the three countries. Second, with regard to brands preferred by the respondents, Korea and China were open to foreign brands, while Japan mostly preferred its domestic brands. Third, this study found changes in the use of cosmetics since the outbreak of COVID-19. The respondents' biggest skin concern since COVID-19 was acne in Korea and Japan and increased sebum excretion in China. Concerns about sebum were commonly ranked high across the three countries. Based on these results, this study is suggested as a reference to improve the export competitiveness of Korean male cosmetics in the ASEAN market.