• Informatization Policy
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• v.18 no.4
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• pp.3-21
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• 2011

Knowledge ecosystem means a dynamic knowledge circulation, including knowledge creation, exchange and sharing and utilization. It is also the field of knowledge practice, which creates interactions in knowledge exchange between people and groups. The key premises of knowledge ecosystem, based on the nature of general ecosystems, can be characterized as follows: first, it primarily focuses on social networks between people and organizations participating in the process of knowledge circulation; secondly, knowledge ecosystem thrives on diversity of knowledge; and thirdly, it is significant for selection of valuable knowledge and adoption of appropriate knowledge. This review attempts to make a systematic examination of a wide range of existing studies on knowledge ecosystem. In so doing, it is expected to provide a basis for further inquiry into more critical and complicated issues. Although the scarcity of existing research-at least those in Korea-may limit the implications of findings, this review offers a set of suggestions for future research.

• Journal of Korean society of Dental Hygiene
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• v.17 no.6
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• pp.957-967
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• 2017

Objectives: This study consisted of a literature review on oral health among people with disabilities, and to present the factors that should be considered in developing an oral health program for people with disabilities. Methods: The key words 'people with disabilities' and 'oral health' were searched in 4 Korean academic journals and 5 online search engines and a total of 635 papers were identified. Duplicate papers were removed, and the literature selection criteria were applied to the remaining papers. Finally, a total of 45 papers were used in the review. Results: First, people with disabilities were the most common research subjects, followed by dental students, dental hygiene students, dentists, dental hygienist and guardians and special education teachers. Second, the most frequently studied research topic was dental examination, followed by oral health behavior and behavior of using dental clinics. Third, research purposes included the status of oral health, the quality of oral health, dental treatment, the use of oral health service, and oral hygiene behavior and perception. Fourth, the most frequently discussed policy task was expansion of research subjects, followed by oral hygiene and policy development. Conclusions: To enhance the oral health of people with disabilities who have difficulty in keeping their teeth clean and healthy on their own, development of an oral hygiene training program is required not only for people with disabilities, but also for guardians and teachers. It is equally important to examine oral health behavior that could potentially affect the status of oral health and create a more accurate and systematic oral hygiene method. In addition, the government, together with various other research institutes, should conduct an oral health survey of a representative sample of people with disabilities to determine oral health status and facilitate improvements to oral hygiene programs.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2001.06a
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• pp.35-39
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• 2001

The Integration Host factor (IHF) of Escherichia coli is a small, basic protein that is required for a variety of functions including site-specific recombination, transposition, gene regulation, plasmid replication, and DNA packaging. It ,is composed of two subunits that are encoded by the ihfA ($\alpha$-subunit) and ihjB ($\beta$-subunit) genes. IHF binding sites are composed of three elements called the WATCAR, TTG, and poly (dAT) elements. We have characterized IHF binding to the H site of bacteriophage λ. We have isolated suppressors that bind to altered H' sites using a challenge phage selection. Two different suppressors were isolated that changed the adjacent $\alpha$P64 and $\alpha$K65 residues. The suppressors recognized both the wild-type site and a site with a change in the WATCAR element. Three suppressors were isolated at $\beta$-E44. These suppressors bound the wild-type and a mutant site with a T：A to A：T change (H44A) in the middle of the TIR element. Site-directed mutagenesis was used to make several additional changes at $\beta$E44. The wild-type and $\beta$E44D mutant could not bind the wild-type site but were able to bind the H44A mutant site. Other mutants with neutral, polar, or a positive charge at $\beta$E44 were able to repress both the wild-type and H44A sites. Examination of the IHF crystal structure suggests that the ability of the wild-type and $\beta$E44D proteins to discriminate between the T：A and A：T basepairs is due to indirect interactions. The $\beta$-E44 residue does not contact the DNA directly. It imposes binding specificity indirectly by interactions with residues that contact the DNA. Details of the proposed interactions are discussed.

• Archives of Plastic Surgery
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• v.43 no.4
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• pp.328-338
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• 2016

Nipple-sparing mastectomy (NSM) is increasingly popular as a procedure for the treatment of breast cancer and as a prophylactic procedure for those at high risk of developing the disease. However, it remains a controversial option due to questions regarding its oncological safety and concerns regarding locoregional recurrence. This systematic review with a pooled analysis examines the current literature regarding NSM, including locoregional recurrence and complication rates. Systematic electronic searches were conducted using the PubMed database and the Ovid database for studies reporting the indications for NSM and the subsequent outcomes. Studies between January 1970 and January 2015 (inclusive) were analysed if they met the inclusion criteria. Pooled descriptive statistics were performed. Seventy-three studies that met the inclusion criteria were included in the analysis, yielding 12,358 procedures. After a mean follow up of 38 months (range, 7.4-156 months), the overall pooled locoregional recurrence rate was 2.38%, the overall complication rate was 22.3%, and the overall incidence of nipple necrosis, either partial or total, was 5.9%. Significant heterogeneity was found among the published studies and patient selection was affected by tumour characteristics. We concluded that NSM appears to be an oncologically safe option for appropriately selected patients, with low rates of locoregional recurrence. For NSM to be performed, tumours should be peripherally located, smaller than 5 cm in diameter, located more than 2 cm away from the nipple margin, and human epidermal growth factor 2-negative. A separate histopathological examination of the subareolar tissue and exclusion of malignancy at this site is essential for safe oncological practice. Long-term follow-up studies and prospective cohort studies are required in order to determine the best reconstructive methods.

• Journal of radiological science and technology
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• v.28 no.4
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• pp.273-277
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• 2005

The rapid development in digital acquisition technology in radiography has not been accompanied by information regarding optimum radiolographic technique for use with an amorphus silicon flat panel detector. The purpose of our study was to compared image quality and radiation dose of an amorphus silicon flat panel detectors for digital chest radiography. All examinations were performed by using an amorphus silicon flat panel detector. Chest radiographs of an chest phantom were obtained with peak kilovoltage values of $60{\sim}150kVp$. Published data on the effect of x-ray beam energy on image quality and patient dose when using an amorphus silicon flat panel detector. It is important that radiographers are aware of optimum kVp selection for an amorphus silicon flat panel detector system, particularly for the commonly performed chest examination.

• Journal of Oriental Neuropsychiatry
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• v.21 no.3
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• pp.29-44
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• 2010

Objectives : The purpose of this research is to examine the efficacy of Gamisoyosan on anxiety of generalized anxiety disorder according to dosage form. Methods : In this randomized, double blinded, placebo-controlled study, we planned to give Gamisoyosan simple extract mixture or Gamisoyosan compound extract or controlled medication for major symptoms of generalized anxiety disorder. As preparatory research, Hamilton rating Scale for Anxiety(HAM-A) was measured as the 1st evaluative instrument, and Korean State-Trait Anxiety Inventory(STAI-K), Penn State Worry Questionnaire(PSWQ) Korean Beck's Depression Inventory (BDI-K), Symptom Checklist-90-Revised(SCL-90R), WHO Quality of Life Abbreviated(WHOQOL-BREF) and Heart Rate Variability(HRV) were also measured as the 2nd evaluative instrument at the before treatment. Results : Demographic characteristics showed that there are Clinical characteristics-vital signs are within the normal range. The characteristics of disease-chief complaint, pattern Identification and etiological factor of the highest frequency number were worry, heart deficiency with timidity(心膽虛怯), family matters. The average period of disease in subjects is 6.31years. The results of Chest PA, EKG and clinicopathologic examination are within the reference range. The Scores of HAM-A, STAI-K, PSWQ were measured above the cutoff point. There are significant positive correlations among HAM-A, STAI-K, BDI-K and among HAM-A, STAI-K, PSWQ. There are no significant correlations between PSWQ and BDI-K. Conclusions : We considered that selection of subjects in this research is appropriately accomplished And this methodology is expected to be applied to the subsequent research. And also, we hope to make up for this study through various study and discussion.

• School Mathematics
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• v.13 no.1
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• pp.89-105
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• 2011

To provide some suggestions on the setting of mathematics test in the College Scholastic Ability Test(CSAT), this paper analyses the result of mathematics test in the CSAT from 2005 to 2011, on which the 7th national mathematics curriculum has been applied. From the result, four suggestions are drawn out. First, the mathematics test needs to be easier to reduce the burden of test-taker. Accordingly, the number of items and their scores need to be adjusted. Second, the proportion of multiple-choice items has to be reduced whereas that of short-answer items has to be increased to enhance the function of the CSAT as a selection test. Third, the sub-item system needs to be adopted. Fourth, new item-types have to be developed.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.39 no.2
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• pp.134-142
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• 2003

Most of the vibration and noise generating in small boats come from shipboard machinery such as main engine, generator and auxiliary machinery etc. In order to build up the comfortable environment for the crew and to reduce the ambient noise, and provide basic materials for reasoning selection application, the design under allowable vibration & noise conditions and the examination of vibration condition of the new ships, this paper researches the frequency spectrum and order analysis of vibration and noise. The obtained results are summarized as follows : Through comparing the small boat internal noise with the regulation of IMO and DNV, it revealed that the noise level of main engine room accords with the standard, and the noise of other places are beyond the values. In this paper, two boats are analyzed, which are same type, same size and power, but the main engines noise of them is different. In order to search the noise source, the noise of main engine room and relative parts are measured. The third order of measured points is dominant in frequency domain by the order analysis.

• Journal of Gifted/Talented Education
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• v.11 no.2
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• pp.59-85
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• 2001

Offered in this paper are standards for evaluation of a center for scientifically gifted education attached to a university. Various methods of study are used, such as review of literature, professional meetings, seminars, and discussion groups. To implement this study we first analyzed the current status and problem of the center through examination of already published research in regard to scientifically gifted education. Based on this analysis, we then identified the direction and framework of evaluation of a center for scientifically gifted education attached to a university that could function as a local education center for the gifted. After this, we designed detailed standards for evaluation for such a center in regard to direction, organization, procedures and methods for selection of a center, curriculum development, and strategies of instruction and evaluation according to the characteristics, phase, and function of the center as identified. Lastly, we presented a framework for evaluation concluding standards and methods for evaluation classified by the domains and times of evaluation we had explored. Plans for evaluation of the center as described here, will provide meaningful suggestions enabling centers for scientifically gifted education to improve the quality of their institutions'educational environment.

• Journal of Gifted/Talented Education
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• v.20 no.1
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• pp.61-77
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• 2010

The purpose of this study was to analyze the items that were used in entrance examination for science gifted education center for middle school students by using content analysis and classical item analysis. In content analysis, objective type items exhibited mathematics and physics were dominant. Science giftedness & creativity items were dominant. And essay type items consisted of physics items, have evaluated creative problem solving ability. Item difficulty and discrimination index, on the whole, were appropriate. Comparing with objective type, essay type has higher discrimination index. In correlation analysis between total score and score of each type of items, total score has the highest correlation with essay type items and science giftedness & creativity. It was recommended that mathematics, physics and chemistry items with focusing giftedness & creativity could give some implications for future selection methods of science gifted education center.