• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.18 no.3
• /
• pp.26-36
• /
• 2005

Objectives: Maier symptoms of allergic rhinitis are nasal obstructions, sneezing and watery rhinorrhea. When exposed to certain allergens, the IgE covered mast cells degranulate and release inflammatory mediators and cytokines which result in a local inflammatory reaction. In many recent studies, molecular biological methods have been used to investigate the role of cytokines in pathogenesis and new therapeutic targets of allergic rhinitis. This experimental study was done to reveal the effects of the Bojungikgi-tang on the allergic rhinitis. We have studied effect of mice on OVA-induced production of IL-4, IL-5, $INF-{\gamma}$ by murine splenocytes and effect of OVA-induced Total IgE and OVA-specific IgE Meterial and Metheds: 21 BALB/c rats were divided into three groups: normal group, control group, experimental group. To induce the allergic rhinitis in control group and experimental group, rats were sentitized intraperitioneally with 0.1% ovalbumin solution 3 times at intervals of 2 weeks. Then intranasal sensitization was performed by diffusing 0.1% ovalbumin solution 3 times at intervals of 2 days for a week. After that time, rats in experimental group were oral administration treated by the Bojuogikgi-tang fer 28 days. We observed changes of IL-4, IL-5, $INF-{\gamma}$, Total IgE and OVA-specific IgE. We used independent-test statistically. Results: 1. In IL-4 study, Bojungikgi-tang treated group didn't show significant differences. 2. In IL-5 study, Bojungikgi-tang treated group shows significant differences. 3. In $INF-{\gamma}$ study, Bojungikgi-tang treated group shows significant differences. 4. In Total IgE, Bojungikgi-tang treated group shows significant differences. 5. In OVA-specific IgE, Bojungikgi-tang treated group didn't show significant differences. According to this result, Bojungikgi-tang was concluded to be effective on lowering the total IgE. Through this. Bojungikgi tang seems to reduce the symptoms of allergic rhinitis. More studies are required to know exact mechanism of Bojungikgi tang to show the anti allergenic effect.

• Archives of Plastic Surgery
• /
• v.37 no.4
• /
• pp.481-484
• /
• 2010

Purpose: Congenital dermoid cysts develop during the fusion of the embryo when the ectodermal tissue gets trapped in the line of fusion. Dermoid cysts of the head are rare lesions comprised of epidermal and mesodermal elements. Furthermore, dermoid cysts in the occipital area are extremely rare. Only a few cases of dermoid cysts in the posterior scalp have been reported. Especially, A bilateral, synchronous presentation in this location has not been reported previously in the literature. Methods: All 5 cases had a gradually enlarging mass of the posterior aspect of the scalp. The cysts were mobile, noncompressible, and non-tender, without evidence of an associated sinus tract, skin dimpling, discoloration, or communication with adjacent structures. The CT scan displayed a hypodense cystic lesions about -87 to +24 HU (Housefield units, average +3.2 HU) with hypodense capsule and no postcontrast enhancement. All tumors were found just under the skin, and were well encapsulated, so they were completely removed the mass with adjacent periosteum. Results: On gross findings, all tumors were oval-or round-shaped, and when the cystic tumor was cut open it presented a greasy and caseous substance. Histologically, all specimens contain desquamated squamous epithelium and keratin in the lumen and are encapsulated and lined by keratinized stratified squamous epithelium. And, all cases of posterior mass are the presence of adnexal structures. Conclusion: Appropriate diagnosis requires not only an index of suspicion for this rare tumor a very careful history and search for skin changes. Especially, CT can reveal the exact location of the cyst, its relationship with the adjacent structures. We think that occipital dermoids divide into superficial and deep type. In our cases, because they did not have intra-cranial involvement or fistula formation, they are superficial type. This report describes the clinical and operative aspects of the superficial dermoid cysts and provides a review of the literatures.

• Water for future
• /
• v.29 no.4
• /
• pp.209-221
• /
• 1996

It may be difficult to make exact estimates of peak discharge or runoff depth of a flood and to establish the proper measurement for the flood protection since water stages or discharges have been rarely measured at small river basins in Korea. Three small catchments in the Su-Young river basin in Pusan were selected for the study areas. Various runoff parameters for the study areas were determined, and runoff analyses were performed using three different runoff models available in literatures; the storage function method, the discrete, linear, input-output model, and the linear reservoir model. The hydrographs calculated by three different methods showed good agreement with the observed flood hydrographs, indicating that the models selected are all capable of sucessfully modeling the flood events for small watersheds. The storage function method gave the best results in spite of its weakness that it could not be applicable to small floods, while the linear reservoir model was found to provide relatively good results with less parameters. The capabilities of simulating flood hydrographs were also evaluated based on the effective rainfall from the storage function parameters, the $\Phi$-index method, and the constant percentage method. For the On-Cheon stream watershed, the storage function parameters provided better estimates of effective rainfall for regenerating flood hydrographs than any others considered in the study. The $\Phi$-index method, however, resulted in better estimates of effective rainfall for the other two study areas.

• The Journal of Internal Korean Medicine
• /
• v.22 no.3
• /
• pp.423-430
• /
• 2001

Objects: The purpose of this case-control study was done to examine the relationship between stroke prevalence and the anthropometric indices(body mass index(BMI), modified Broca's method(Broca's index), waist circumference(WC), waist-hip ratio(WHR)), dyslipidemia, past medical history(heart disease, hypertension, diabetes mellitus(DM)), life-style factors(smoking, drinking) in Korean adults. Methods : The study group consisted of neurologically confirmed 116 stroke patients as the case group and 116 non-stroke patients as control group. Obesity were defined as $BMI{\geq}25kg/m^2,\;Broca's\;index{\geq}30%$, WC >94cm in male and WC >80cm in female, $WHR{\geq}0.9$ in male and $WHR{\geq}0.8$ in female. Oyslipidemia were defined as total $cholesterol{\geq}200mg/dl,\;triglyceride{\geq}200mg/dl,\;HDL-cholesterol {\leq}35mg/dl,\;LDL-cholesterol{\geq}160mg/dl$. Information on life-style factors and past medical history was obtained from personal interview. The analysis of the data was done by means of chi-square test(Pearson's chi-square test, Fisher's exact test) and student t-test. Results: The results were as follow. In the study group: Hypertension had a 4:05 odds ratio, Broca's $index{\geq}30%$ had a 1.98 odds ratio, WC >94cm in male had a 2.17 odds ratio, WC >80cm in female had a 2.80 odds ratio, $WHR{\geq}0.9$ in male had a 4.66 odds ratio, $WHR{\geq}0.8$ in female had a 5.35 odds ratio, but heart disease, DM, life-style factors, serum lipid and 8MI had no direct relationship with odds ratio(nonsignificant). By student t-test, risk factors for stroke were found to be total cholesterol(p=0,025), LDL-cholesterol(p=0.013), WC(p=0.000) and WHR(p=0.000). Conclusions: This study suggests that people should be advised to control hyperlitension, hyperlipidemia and obesity since these carry a risk of stroke.

• Journal of Hospice and Palliative Care
• /
• v.18 no.3
• /
• pp.227-234
• /
• 2015

Purpose: This study was done to analyze how a death preparation education program have the effects on awareness of hospice palliative care and withdrawing life sustaining treatment in older adults. Methods: This study employed a non-equivalent control group design among quasi-experimental designs. The experimental group was comprised with 35 adults and the control group with 40 adults. The death preparation program consisted of five two-hour sessions and was administered once a week for five straight weeks. Data were analyzed by descriptive statistics, t-test, ${\chi}^2$ test, Fisher's exact test, and ANCOVA using SPSS version 18.0. Results: The mean age of the participants was 66.2 years. A significant difference between the experimental and control groups was observed in withdrawing life sustaining treatment (F=3.380, P=0.040). However, no significant difference was found in awareness of hospice palliative care (F=0.163, P=0.850). Conclusion: The study results indicate that death preparation training could positively affect people's awareness of withdrawing life sustaining treatment. More studies should be conducted to explore effects of death preparation education for all ages and help people better understand hospice palliative care.

• The Korean Journal of Emergency Medical Services
• /
• v.12 no.1
• /
• pp.53-67
• /
• 2008

Purpose : This study is descriptive correlation research to provide basic materials for developing program which can give practical assistance in preventing and managing obesity through more comprehensive approaches of influential factors on obesity found in existing literatures. Methods : Data were collected from the 4th, 5th and 6th graders at 2 elementary schools in Gwangju Metropolitan City and 4 elementary schools in Jeollanamdo province using questionnaire and students' physical examination results from June 15 to July 27, 2006 and data obtained from 1,866 students were used for analysis. Data collected were analyzed with technical statistics and correlation analysis using SPSS/PC(version 12.0). Results : 1. Obesity level of elementary school students was examined as follows; 33.2% had low weight, 44.3% normal, 10.8% overweight and 11.7% obese. 14.8% of boys and 8.6% of girls, 13.5% of the 4th graders, 12.1% of the 5th graders and 9.2% of the 6th graders, and 13.7% of urban students and 9.6% of rural students were obese. 2. According to general characteristics and obesity of the subjects, there were significant differences by sex(${\chi}^2=29.55$, p= .000), grade(${\chi}^2=12.84$, p= .046), region(${\chi}^2=41.96$, p= .000) and pocket money(${\chi}^2=33.43$, p= .001). 3. As genetic factors, all variables including sibling's obesity r= .128(p= .000), mother's obesity r= .098(p= .000) and father's obesity r= .081(p= .001) had influence on children's obesity. 4. Concerning environmental factors, there was positive correlation between eating habits r=- .052(p= .02) and school record r=- .048(p= .04) and there was negative correlation between internet using time r= .050(p= .03) and conflict with parents r= .048(p= .04). 5. Self-respect as psychological factor had negative correlation as r=- .048(p= .04). Conclusion : Consequently, the influential factors on obesity of elementary school students were as follows. Obesity was higher in boys than in girls, in urban areas than in rural areas, in lower grade than in higher grade, in children with obese siblings, obese father and mother, irregular and wrong eating habits, frequent internet uses, parents in conflict and lower school record and self-respect. Therefore, since it was found that these variables were more exact causes to increase children's obesity, development of various obesity mediation programs considering these variables at home, school and society is urgently required.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.52 no.4
• /
• pp.62-70
• /
• 2015

Recently the demand for projected capacitance touch screens is sharply growing especially for large screens for medical devices, PC monitors and TVs. Large touch screens in general need a controller of higher complexity. They usually have a larger number of driving and sensing lines, and hence it takes longer to scan one frame for touch detection leading to a low frame scan rate. In this paper, a novel touch screen control technique is presented, which scans each frame in two steps of simultaneous multi-channel driving. The first step is to drive all driving lines simultaneously and determine which sensing lines have any touch. The second step is to sequentially rescan only the touched sensing lines, and determine exact positions of the touches. This technique can substantially increase the frame scan rate. This technique has been implemented using an FPGA and an AFE board, and tested using a commercial 23-inch touch screen panel. Experimental results show that the proposed technique improves the frame scan rate by 8.4 times for the 23-inch touch screen panel over conventional methods.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.27 no.6
• /
• pp.846-855
• /
• 2021

Eco-friendly and renewable energy sources are actively being researched in recent times, and of shore wind power generation requires advanced design technologies in terms of increasing the capacities of wind turbines and enlarging wind turbine installation vessels (WTIVs). The WTIV ensures that the hull is situated at a height that is not affected by waves. The most important part of the WTIV is the leg structure, which must respond dynamically according to the wave, current, and wind loads. In particular, the wave load is composed of irregular waves, and it is important to know the exact dynamic response. The dynamic response analysis uses a single degree of freedom (SDOF) method, which is a simplified approach, but it is limited owing to the consideration of random waves. Therefore, in industrial practice, the time-domain analysis of random waves is based on the multi degree of freedom (MDOF) method. Although the MDOF method provides high-precision results, its data convergence is sensitive and difficult to apply owing to design complexity. Therefore, a dynamic amplification factor (DAF) estimation formula is developed in this study to express the dynamic response characteristics of random waves through time-domain analysis based on different variables. It is confirmed that the calculation time can be shortened and accuracy enhanced compared to existing MDOF methods. The developed formula will be used in the initial design of WTIVs and similar structures.

• Journal of Korean Neurosurgical Society
• /
• v.64 no.6
• /
• pp.913-921
• /
• 2021

Objective : Accurate measurement of T1 slope (a component of T1s minus cervical lordosis [CL]) is often constrained by anatomical limitations. In this situation, efforts should be made to find the exact meaning of T1s-CL and whether there are any alternatives to it. Methods : We enrolled 117 patients who received two-level anterior cervical discectomy and fusion (ACDF). Occipital slope, C2 slope (C2s), C7 slope (C7s), T1, O-C2 angle (O-C2A), C2-7 angle (C2-7A), O-C7 angle (O-C7A), T1s-CL, C7-T1 angle (C7-T1A), and C2-7 sagittal vertical axis were measured. We determined 16° (T1s-CL) as the reference point for dividing subjects into the mismatch group and the balance group, and a comparative analysis was performed. Results : The mean value of C7-T1A was constantly maintained within 2.6° peri-operatively. In addition, C2s and T1s-CL showed the same absolute change (Δ|0.8|°). The mean values of T1s-CL of the mismatch and balance groups were 23.0° and 7.6°, respectively. The five factors with the largest differences between the two groups were as follows : C2s (Δ13.3°), T1s-CL (Δ15.4°), O-C2A (Δ8.7°), C2-7A (Δ14.7°), and segmental angle (Δ7.9°) before surgery. Only four factors showed statistically significant change between the two groups after ACDF : T1s-CL (Δ4.0° vs. Δ0.2°), C2s (Δ3.2° vs. Δ0.7°), O-C2A (Δ2.6° vs. Δ1.3°), C2-7A (Δ6.3° vs. Δ1.3°). A very strong correlation between T1s-CL and C2s was also found (r=|0.88-0.96|). Conclusion : C2s itself may be the essential key to represent T1s-CL. The amounts and directions of change of these two factors (T1s-CL and C2s) were also almost identical. The above phenomenon was re-confirmed once again through the correlation analysis.

• Nutrition Research and Practice
• /
• v.15 no.6
• /
• pp.715-731
• /
• 2021

BACKGROUND/OBJECTIVES: Premenstrual syndrome (PMS) is a disorder characterized by repeated emotional, behavioral, and physical symptoms before menstruation, and the exact cause and mechanism are uncertain. Hyperprolactinemia interferes with the normal production of estrogen and progesterone, leading to PMS symptoms. Thus, we judged that the inhibition of prolactin hypersecretion could mitigate PMS symptoms. MATERIALS/METHODS: Hordeum vulgare L. extract (HVE), Chrysanthemum zawadskii var. latilobum extract (CZE), and Lomens-P0 the mixture of these extracts were tested in subsequent experiments. The effect of extracts on prolactin secretion at the in vitro level was measured in GH3 cells. Nitric oxide and pro-inflammatory mediator expression were measured in RAW 264.7 cells to confirm the anti-inflammatory effect. Also, the hyperprolactinemic Institute for Cancer Research (ICR) mice model was used to measure extract effects on prolactin and hormone secretion and uterine inflammation. RESULTS: Anti-inflammatory effects of and prolactin secretion suppress by HVE and CZE were confirmed through in vitro experiments (P < 0.05). Treatment with Lomens-P0 inhibited prolactin secretion (P < 0.05) and restored normal sex hormone secretion in the hyperprolactinemia mice model. In addition, extracts significantly inhibited the expression of pro-inflammatory biomarkers, including interleukin-1𝛽, and -6, tumor necrosis factor-𝛼, inducible nitric oxide synthase, and cyclooxygenase-2 (P < 0.01). We used high-performance liquid chromatography analyses to identify tricin and chlorogenic acid as the respective components of HVE and CZE that inhibit prolactin secretion. The Lomens-P0, which includes tricin and chlorogenic acid, is expected to be effective in improving PMS symptoms in the human body. CONCLUSIONS: The Lomens-P0 suppressed the prolactin secretion in hyperprolactinemia mice, normalized the sex hormone imbalance, and significantly suppressed the expression of inflammatory markers in uterine tissue. This study suggests that Lomens-P0 may have the potential to prevent or remedy materials to PMS symptoms.