• 제목/요약/키워드: evidence choice

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기분부전장애와 비전형우울증의 약물치료 (Pharmacological Treatments for Dysthymic Disorder and Atypical Depression)

  • 임세원;오강섭
    • 생물정신의학
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    • 제14권1호
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    • pp.14-20
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    • 2007
  • Objectives : The diagnosis of depression is based on a highly variable set of symptoms. Therefore, depression should not be viewed as a single disease, but a heterogenous syndrome comprised of different pathophysiologies. There are several subtypes of depression which were already incorporated in DSM-IV. This article provides a systematic review of pharmacological treatments of two recognized subtypes of depression-dysthymic disorder and atypical depression. Methods : Systematic search of relevant literatures on dysthymic disorder and atypical depression was performed by proposed search strategy of the Clinical Research Center for Depression of Korean Health 21 R&D Project. All identified literatures were carefully reviewed and classified according to SIGN grading system and summarized in a narrative manner. Results : For the treatment of dysthymic disorder and atypical depression, selective serotonin reuptake inhibitors( SSRIs) and moclobemide have more evidence than the other antidepressants. SSRIs and moclobemide showed superior tolerability than tricyclic antidepressants. Conclusions : The authors proposed treatment recommendations for dysthymic disorder and atypical depression by the methods of evidence-based medicine(EBM). However, guideline developing methods of EBM also have several inevitable limitations. Therefore, in the absence of clear and significant differences in efficacy, the choice of medication must be individualized for a particular patient based on psychiatrist's own clinical decision.

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미숙아의 장관영양 (Enteral Feeding for Preterm Infants-Benefits and Risks)

  • 신종범
    • Neonatal Medicine
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    • 제16권2호
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    • pp.121-130
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    • 2009
  • Over the past 20 years, neonatal mortality rates for preterm infants, particularly those born extremely preterm and with a very low birth weight, have decreased steadily. As more very immature preterm infants survive, provision of enteral feeding has become a major focus of concern. According to many experts on neonatal nutrition, the goal for the nutrition of preterm infants should be to achieve a postnatal growth rate approximating that of a normal fetus of the same gestational age. Total parenteral nutrition for maintaining nutritional integrity is mandatory before successful transition to enteral feeding. Early initiation of trophic enteral feeding is vital for postnatal adaptation. Recently published randomized controlled trials provide no evidence to support the practice of postponing enteral feeding to reduce the incidence of necrotizing enterocolitis. Early trophic feeding yields demonstrable benefits and there is currently no evidence of any adverse effects following early feeding. Preterm milk from the infant's own mother is the milk of choice, which can always be supplemented with a human milk fortifier. Here we review over 50 randomized controlled trials and over seven systematic reviews published on neonatal parenteral and enteral feeding of preterm infants. Neonatologists must make use of the evidence from these studies as a reference for feeding protocols for preterm infants in their NICUs are to be based.

Factors Affecting the Choice of Banks: Do Bank's Interest Rate, Employee Image and Brand Matter?

  • DAO, Le Kieu Oanh;LOC, Huynh Huu;NGUYEN, Van Chien;HANG, Le Thi Thuy;DO, Thi Tuyet
    • The Journal of Asian Finance, Economics and Business
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    • 제8권1호
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    • pp.457-470
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    • 2021
  • The banking system provides a number of important functions for the economy and is also the lifeblood and financier of the economy in each country. Large amounts of idle money have not been exploited by banks; however, banks still depend on loans, including loans from foreign banks, to meet the growing demand, as such, for banks, the cost of capital is high, the stability and business efficiency are low and banks have not promoted their internal resources to grow steadily. To achieve the goal, this research analyzes the factors affecting the choice of bank for the deposit decisions of customers in Vietnam. The study used a sample data of 250 individuals and SPSS software was used to analyze the data. The results showed that customer policy has a positive effect on customers' deposit decisions in a bank, and this is new evidence regarding behavioral theory in the case of Vietnam. Results further demonstrated that other factors such as employee image, brand, interest rate, relative influencing, and transaction time positively impact the choice of bank for the deposit decisions of customers. However, the bank's promotion strategies had no impact on the choice of bank for the deposit decisions of customers. Besides, employee image is the most influential factor in the deposit decisions, followed by the bank's brand and interest rate.

Determinants of Capital Structure:The Case in Vietnam

  • VU, Thu Minh Thi;TRAN, Chung Quang;DOAN, Duong Thuy;LE, Thang Ngoc
    • The Journal of Asian Finance, Economics and Business
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    • 제7권9호
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    • pp.159-168
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    • 2020
  • This is a quantitative research, underpinned by the philosophy of natural science and deduction approach that examines the impact of the various aspects of corporate governance mechanism on the choice of capital structure of Vietnamese listed firms. We focus on the effect of factors such as the board size, the board independence, and especially different ownership structures, which include the managerial ownership, the state ownership, the concentrated ownership, and the foreign ownership. They are the main scopes of corporate governance and are supposed to be relevant to determine the corporate financing choice. To explain the causal relationship between factors, we construct the regression model and then test it by using different statistical method approaches, including the pooled OLS, the fixed effects model, and the random effects model. Data are collected from 336 firms with shares listed in the Ho Chi Minh City Stock Exchange in Vietnam, totaling 1583 observations. Overall, the results reveal that the board size, state ownership, and concentrated ownership have positive impact on the firm's capital structure, whereas foreign ownership appears to have negative influence on the capital structure. The research does not find evidence of a the correlation between board independence, managerial ownership and corporate capital struture.

Agglomeration Effects and Foreign Direct Investment Location Choice: Cross-country Evidence from Asia

  • Choi, Paul Moon Sub;Chung, Chune Young;Lee, Kaun Y.;Liu, Chang
    • Journal of Korea Trade
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    • 제24권1호
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    • pp.35-58
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    • 2020
  • Purpose - This study examines the determinants of foreign direct investment (FDI) location choice for Chinese firms, focusing on the agglomeration effect for firms of the same nationality. Design/methodology - The empirical data are China's inward FDI from the top 19 economies (excluding tax havens and Taiwan) in terms of FDI during 1997-2015 and China's outward FDI from the top 18 economies (excluding tax havens). This study uses a random effects generalized least squares model for panel data analysis. Findings - The results confirm that both host countries' costs and market conditions and the degree of agglomeration affect these countries' attractiveness for FDI inflows. Specifically, agglomeration has a significant effect on China's inward and outward FDI. This study confirms that the agglomeration of firms of the same nationality has predictive power for multinational enterprises' FDI location choices. The host countries' real GDP and trade openness also positively affect FDI inflows. Interestingly, however, China's production cost has a positive effect. Thus, inward FDI aimed at entering the Chinese market is increasing in recent years relative to the previous efficiency-seeking FDI. Inward FDI in China is therefore the market-entry type, whereas outward FDI by Chinese firms is the market-oriented type. Originality/value - These results suggest that the effects of the potential determinants of Chinese outward FDI are similar to those of inward FDI as China's trade liberalization progresses.

Factors Affecting Consumer's Choice of Retail Store Chain: Empirical Evidence from Vietnam

  • BUI, Thu Thi;NGUYEN, Huong Thi;KHUC, Long Dai
    • The Journal of Asian Finance, Economics and Business
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    • 제8권4호
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    • pp.571-580
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    • 2021
  • The study explores the factors affecting the brand selection behavior of retail chains in Vietnam and to what extent they have an impact on the customer's choice intention. This research employs a combination of both qualitative and quantitative mixed methods with the help of SPSS version 22.0 in data analysis. Expert interviews are used to design the questionnaire for the survey conducted on 700 consumers. Research results show that the eight factors of store image (1-to-3 split factor of store image including the display of goods and services), price perception, risk perception, brand attitude, brand awareness, and brand familiarity were determined. They all influence the intention to choose the retail chain brand. With a positive β coefficient, the more store image, price perception, brand attitude, and brand awareness are enhanced, the more likely the intention to choose the retail chain brand. The factor of risk perception has negative ��, resulting in an inverse impact on choosing a retail chain brand name. Price perception and risk perception have the strongest impact on retail chain decision behavior while commodity display factors the least. Based on these important results, the study proposes implications for retailers and manufacturers.

Proximal Gastrectomy for Gastric Cancer

  • Jung, Do Hyun;Ahn, Sang-Hoon;Park, Do Joong;Kim, Hyung-Ho
    • Journal of Gastric Cancer
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    • 제15권2호
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    • pp.77-86
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    • 2015
  • Laparoscopic proximal gastrectomy (LPG) is theoretically a superior choice of minimally-invasive surgery and function-preserving surgery for the treatment of proximal early gastric cancer (EGC) over procedures such as laparoscopic total gastrectomy (LTG), open total gastrectomy (OTG) and open proximal gastrectomy (OPG). However, LPG and OPG are not popular surgical options due to three main concerns: the first, oncological safety; the second, functional benefits; and the third, anastomosis-related late complications (reflux symptoms and anastomotic stricture). Numerous recent studies have concluded that OPG and LPG present similar oncological safety profiles and improved functional benefits when compared with OTG and LTG. While OPG with modified esophagogastrostomy does not provide satisfactory results, OPG with modified esophagojejunostomy showed similar rates of anastomosis-related late complications when compared to OTG. At this stage, no standard reconstruction method post-LPG exists in the clinical setting. We recently showed that LPG with double tract reconstruction (DTR) is a superior choice over LTG for proximal EGC in terms of maintaining body weight and preventing anemia. However, as there is no definitive evidence in favor of LPG with DTR, a randomized clinical trial comparing LPG with DTR to LTG was recommended. This trial, the Korean Laparoscopic Gastrointestinal Surgery Study-05 (NCT01433861), is expected to assist surgeons in choice of surgical approach and strategy for patients with proximal EGC.

제18대 대통령 선거에서 이념의 영향: 패널 데이터 분석 결과 (The Role of Political Ideology in the 2012 Korean Presidential Election: Evidence from Panel Data Analysis)

  • 김성연
    • 의정연구
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    • 제23권2호
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    • pp.147-177
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    • 2017
  • 한국 선거에서 정치 이념의 역할에 대해 그동안 수많은 연구가 이루어졌으나, 지금까지의 연구들은 예외 없이 횡단면 데이터(cross-sectional data) 분석에 전적으로 의존하였다. 기존의 연구들과 달리 이 연구는 지난 제18대 대통령 선거에서 나타난 이념 투표의 영향을 패널 데이터 분석(panel data analysis)을 통해 보다 엄밀하게 검증한다. 구체적으로, "EAI 총선대선패널조사, 2012"를 이용하여 지난 18대 대통령 선거 시기(2012년 4월 중순-12월 하순)에 정치적이념이 유권자들의 후보 호오도(candidate evaluation)와 후보 선택(vote choice)에 미친 영향을 고정 효과(fixed effects) 분석과 변동 효과(random effect) 분석 등 표준적인 패널 데이터 분석을 통해 살펴보았다. 또한 이념투표의 대표적 설명 모형인 근접성 모형(proximity model)과 방향성 모형(directional change model)을 적용한 결과를 비교 분석하였다. 분석 결과, 지난 18대 대통령 선거에서 진보와 보수의 정치적 이념은 박근혜와 문재인후보에 대한 호오도 및 이들에 대한 지지에 독립적이고 유의미한 영향을 미쳤다고 할 수 있다. 즉, 유권자들은 특정 후보와의 이념적 차이가 크다고 느낄수록 그후보에 대한 지지 확률 및 호오도가 상대적으로 낮아졌다. 그리고 이러한 이념투표의 영향은 근접성 모형보다 방향성 모형에서 상대적으로 뚜렷하게 나타났다.

근막이완술과 Mulligan 기법이 경부성 두통환자의 통증과 기능회복에 미치는 영향 (Effects of Myofacial Release and Mulligan Technique on Pain and Disability for Cervicogenic Headache Patients)

  • 전재국;김명준
    • 대한정형도수물리치료학회지
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    • 제18권2호
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    • pp.87-93
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    • 2012
  • Background: Headaches arising from cervical musculoskeletal disorders are common. Conservative therapies are recommended as the choice of first treatment. Evidence to the effects of manual therapy is inconclusive and available only during the short term. There is no evidence to exercise, and no study has investigated the effect of combined therapies for cervicogenic headache. Methods: In this study, 30 participants who met the diagnostic criteria for cervicogenic headache were randomized into two groups: experimental group and control group. The experimental group was performed myofascial release (MFR), Mulligan technique and self stretching exercises. The control group was performed electrical therapy and self stretching exercises. Assessments were performed to 30 participants before and after 4 weeks therapy. The components of assessments were headache intensity(HI), headcahe duration (HD), neck pain (NP) and neck disability index (NDI). Results: After 4 weeks therapy, HI, HD, neck pain and NDI were significantly reduced in both groups (p<.01). The HI, HD, neck pain and NDI were significantly reduced in experimental group more than in the control group (p<.01). Conclusions: Manual therapy could reduce the symptoms of cervicogenic headache.

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Product versus Process Innovation and the Global Engagement of Firms

  • Jang, Yong Joon;Hyun, Hea-Jung
    • Journal of Korea Trade
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    • 제25권4호
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    • pp.37-59
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    • 2021
  • Purpose - Although models of innovation and exporting dominate recent studies of relations between innovation and access to foreign markets, relations between innovation and foreign direct investment (FDI) are less explored. This is especially true of relations between types of innovation and FDI. We fill that gap in the literature with empirical evidence that clarifies whether firms enter foreign markets through exports or FDI. Design/methodology - In order to assess the role of innovation in firms' international engagement strategies, we develop research hypotheses and present new empirical evidence on firms' choice of entry - exports and FDI - based on firm-level data. Findings - Our empirical results suggest that the impact of product innovation is more significant in transition from being a purely domestic firm to an exporter, while process innovation more significantly affect transition from being an exporter to a multinational enterprise. Our results also support 'self-selection into FDI' rather than 'learning-by-performing FDI' in the relationship between innovation and firms' overseas expansion. Originality/value - Recent literature on the relationship between innovation and firms' participation in foreign markets is dominated by models of innovation and export behavior. However, foreign direct investment by multinational enterprises may also be associated with firms' innovative activities. We first analyze how product and process innovations influence firms' choices to initiate exports or FDI.