• Asian-Australasian Journal of Animal Sciences
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• v.15 no.7
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• pp.1045-1050
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• 2002

The aims of this study were to detect spontaneously occurring apoptosis in cultured porcine ovarian cells, to examine the role of growth hormone (GH), tyrosine kinase (TK), protein kinase G (PKG) and cyclin-dependent kinase (CDK) in the control of this process, and to determine whether the effect of GH on apoptosis is mediated by TK-, PKG- and cdc2-dependent intracellular mechanisms. We studied the action of pGH (10 ng/ml), blockers of TK (genistein, lavendustin, both 100 ng/ml), PKG (Rp-Br-PET-cGMPS, 50 nM; KT5823, 100 ng/ml) and CDK (olomoucine, $1{\mu}g/ml$), as well as combinations of GH with these blockers, on the onset of apoptosis in cultured granulosa cells isolated from antral (3-6 mm) porcine follicles. The functional characteristics of an early apoptotic event, DNA fragmentation, were determined using terminal deoxynucleotidyltransferase (TdT)-mediated dUTP nick end labelling (TUNEL), whilst morphological signs of advanced apoptosis such as pyknosis, chromatin marginalization, shrinkage and fragmentation of nucleus, were detected using routine light microscopy. After culture, some ovarian granulosa cells exhibited DNA fragmentation, which in some cases was associated with morphological apoptosis-related changes (pyknosis, shrinkage and fragmentation of the nucleus). GH significantly reduced the proportion of TUNEL-positive cells. Neither TK nor CDK blockers when given alone, significantly affected the percentage of TUNEL-positive cells although both PKG blockers significantly increased this index. Furthermore, TK and PKG blockers given together with GH, prevented or reversed the inhibitory effect of GH on apoptosis, whilst the CDK blocker olomoucine promoted it. These observations demonstrate apoptosis in porcine ovaries and suggest the involvement of GH, TK, PKG and CDK in the control of this process. They also suggest that the effect of GH on ovarian apoptosis is mediated or regulated by multiple signalling pathways including TK-, PKG- and CDK-dependent intracellular mechanisms.

• Journal of the Korea Society for Simulation
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• v.18 no.3
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• pp.147-154
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• 2009

In this study we investigate the problem of reducing color change cost at painting operations in an automobile assembly plant. Changing control logic at conveyor junction points prior to the top coat line has been proposed and analyzed using the discrete event simulation model we developed using AutoMod. We also discussed the project which initiated this research as well as the details of painting operations. Simulation analysis showed that the grouping ratio increases from 1.8 to 2.5 if the proposed control logic change is applied to the plant. Contrary to other approaches such as using dedicated equipment for resequencing, our approach has the merit of less investment cost, no need for additional space consumption. We finally note that the grouping ratio can be further increased if our algorithms is implemented as well as CRS (Color Rescheduling Storage) is installed.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.10-17
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• 2014

The focus maintains and manages conference session in the conference service. Load of focus increases by the number of participants and it becomes the major reason that limits the extendability of the large-scale conference service. In this paper, a new distributed focus control method has been proposed to solve this problem. Load of focus has been distributed to several conference nodes to implement large-scale conference service in this architecture. Conference nodes which have focus function subscribe to conference server's conference information database, and focus hae been allocated dynamically to process participants needs according to total numbers of the conference participants. For this purpose a new conference control event package for focus load control has been suggested. Furthermore the exchange procedure of SIP messages between focuses and participants also been suggested. The performance of the proposed system has been evaluated by simulation.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.10
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• pp.94-117
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• 1998

This paper investigates the performance characteristics of the data link layer of the 1996 version of IEC/ISA fieldbus which is developed as internatioal standard of fieldbus. A discrete-event simulation model of the data link layer of IEC/ISA fieldbus is developed. Using the simulation model, this paper identifies the network parameters that influence the performance of prioritys scheme and real-time data transmission, and analyzes the delay performance of IEC/ISA fieldbus with respect to the change of network parameters. The simulation model also integrates continuous-time simulation model of a control system as application process. Using the integrated simulation model, this study investigates the effect of network-induced delay on the performance of control system. Since the simulation model developed in this study can predict the network performance, it will be effectively utilized in the design phase of control and automation systems that adopt the IEC/ISA fieldbus.

• KIPS Transactions on Computer and Communication Systems
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• v.10 no.7
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• pp.199-204
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• 2021

Digital substation refers to a substation that digitizes functions and communication methods of power facilities such as monitoring, measuring, control, protection, and operation based on IEC 61850, an international standard for the purpose of intelligent power grids. Based on the intelligent operating system, efficient monitoring and control of power facilities is possible, and automatic recovery function and remote control are possible in the event of an accident, enabling rapid power failure recovery. With the development of digital technology and the expansion of the introduction of eco-friendly renewable energy and electric vehicles, the spread of direct current distribution systems is expected to expand. MVDC is a system that utilizes direct current lines with voltage levels and transmission capacities between HVDCs applied to conventional transmission systems and LVDCs from consumers. Converting existing lines in substations, where most power equipment is alternating current centric, to direct current lines will reduce transmission losses and ensure greater current capacity. The process bus of a digital substation is a communication network consisting of communication equipment such as Ethernet switches that connect installed devices between bay level and process level. For MVDC linkage to existing digital substations, the process level was divided into two buses: AC and DC, and a system that can be comprehensively managed in conjunction with diagnostic IEDs as well as surveillance and control was proposed.

• The Journal of the Acoustical Society of Korea
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• v.39 no.5
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• pp.414-423
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• 2020

In this paper, we propose a Dilated Convolution Gate Linear Unit (DCGLU) to mitigate the lack of sparsity and small receptive field problems caused by the segmentation map extraction process in sound event detection with weak labels. In the advent of deep learning framework, segmentation map extraction approaches have shown improved performance in noisy environments. However, these methods are forced to maintain the size of the feature map to extract the segmentation map as the model would be constructed without a pooling operation. As a result, the performance of these methods is deteriorated with a lack of sparsity and a small receptive field. To mitigate these problems, we utilize GLU to control the flow of information and Dilated Convolutional Neural Networks (DCNNs) to increase the receptive field without additional learning parameters. For the performance evaluation, we employ a URBAN-SED and self-organized bird sound dataset. The relevant experiments show that our proposed DCGLU model outperforms over other baselines. In particular, our method is shown to exhibit robustness against nature sound noises with three Signal to Noise Ratio (SNR) levels (20 dB, 10 dB and 0 dB).

• (The)Study of the Eastern Classic
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• no.37
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• pp.93-126
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• 2009

This study is about a event, which happened on January of 1603 in Hamheung. It has covered from the beginning through the conclusion of the event. The event was ignited by a naturalized citizen, Guilsang's coming to the capital city without permission from the government. With this study I've wished to find the situations of specific management of naturalized citizens as well as popular attitudes towards them at the time. Concerning with the event of Guilsang, I could find more detailed situations from "Naturalization Registration". The reason why Guilsang came to Seoul was that he wanted to ask for living together with his son-in-law's family in Yang-Ju. Before his coming, Bie-Byun-Sa had sent a official letter to the governor of Hamkyung-Do so that he had had to move somewhere between Anbyun and Yung-heung. But Guilsang had wanted to live with his whole family in Seoul. The place he visited first was Sa-Yuk-Won. He presented his petition through Yeozin language translator there. Sa-Yuk-Won then informed Ye-Jo to have him investigated. After its investigation, Ye-Jo reported to the king. There were arguments about Guilsang family in the government. Guilsang had wanted to live with his whole family, including his relatives and son-in-law. Guilsang's request had more pros than cons in terms of humanism. But letting him live in Seoul was a difficult decision for the government. but his family strenuously insisted on living in Seoul, trying to kill itself. Finally Government selected Yong-In which was a compromise between the naturalized citizens' wish and difficult position of Government. Yong-In Miejo-Hyun was a poor region where naturalized citizens had lived before but now empty after the wars. In the process of the event of Guilsang, Government differentiated naturalized citizens from general citizens and regarded them foreign. A man from Yeozin was naturalized due to economic reason. But, he couldn't accept to live somewhere except Seoul, separating from his family. Government concerned with dangers of naturalized citizen becoming into foreign agents and stabilization of borders. These concerns caused the policy of residential control and decentralization of naturalized citizens failed.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.5
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• pp.688-699
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• 2017

Model-based test, a well-known method of the black box tests, is consisted of the following four steps : model construction using requirement, test case generation from the model, execution of a SUT (software under test) and detection failures. Among models constructed in the first step, state-based models such as UML standard State Machine are commonly used to design event-based embedded systems (e.g., weapon control systems). To generate test cases from state-based models in the next step, coverage-based techniques such as state coverage and transition coverage are used. Round-trip path coverage technique using W-Method, one of coverage-based techniques, is known as more effective method than others. However it has a limitation of low failure observability because the W-Method technique terminates a testing process when arrivals meet states already visited and it is hard to decide the current state is completely same or not with the previous in the case like the GUI environment. In other words, there can exist unrevealed faults. Therefore, this study suggests a Extended W-Method. The Extended W-Method extends the round-trip path to a final state to improve failure observability. In this paper, we compare effectiveness and efficiency with requirement-item-based technique, W-Method and our Extended W-Method. The result shows that our technique can detect five and two more faults respectively and has the performance of 28 % and 42 % higher failure detection probability than the requirement-item-based and W-Method techniques, respectively.

• Nuclear Engineering and Technology
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• v.41 no.3
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• pp.247-270
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• 2009

This paper reviews studies on information searching behavior in process control systems and discusses some implications learned from previous studies for use in human factors studies on nuclear power plants (NPPs) main control rooms (MCRs). Information searching behavior in NPPs depends on expectancy, value, salience, and effort. The first quantitative scanning model developed by Senders for instrument panel monitoring considered bandwidth (change rate) of instruments as a determining factor in scanning behavior. Senders' model was subsequently elaborated by other researchers to account for value in addition to bandwidth. There is also another type of model based on the operator's situation awareness (SA) which has been developed for NPP application. In these SA-based models, situation-event relations or rules on system dynamics are considered the most significant factor forming expectancy. From the review of previous studies it is recommended that, for NPP application, (1) a set of symptomatic information sources including both changed and unchanged symptoms should be considered along with bandwidth as determining factors governing information searching (or visual sampling) behavior; (2) both data-driven monitoring and knowledge-driven monitoring should be considered and balanced in a systematic way; (3) sound models describing mechanisms of cognitive activities during information searching tasks should be developed so as to bridge studies on information searching behavior and design improvement in HMI; (4) the attention-situation awareness (A-SA) modeling approach should be recognized as a promising approach to be examined further; and (5) information displays should be expected to have totally different characteristics in advanced control rooms. Hence much attention should be devoted to information searching behavior including human-machine interface (HMI) design and human cognitive processes.

• Convergence Security Journal
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• v.9 no.4
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• pp.1-6
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• 2009

Current paradigm of industrial security is changing into the effective operation and management from simple establishment of security equipments. If the physical security system(entry control system, video security system, etc.) and the IT integrated security control system are conversed, it makes us possible to prevent, disrupt and track afterwards the insider's information leakage through the risk and security management of enterprise. That is, Without the additional expansion of the existing physical security and IT security manpower, the establishment of systematic conversion security management process in a short time is possible and can be expected the effective operation of professional organization system at all times. Now it is needed to build up integrated security management system as an individual technique including the security event collection and integrated management, the post connected tracking management in the case of security accident, the pattern definition and real time observation of information leakage and security violation, the rapid judgement and response/measure to the attempt of information leakage and security violation, the establishment of security policy by stages and systematically and conversion security.