• 제목/요약/키워드: evaluation analysis

검색결과 25,480건 처리시간 0.047초

Establishment of the Korean Tolerable Daily Intake of Bisphenol A Based on Risk Assessments by an Expert Committee

  • Choi, Chan-Woong;Jeong, Ji-Yoon;Hwang, Myung-Sil;Jung, Ki-Kyung;Lee, Kwang-Ho;Lee, Hyo-Min
    • Toxicological Research
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    • 제26권4호
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    • pp.285-291
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    • 2010
  • Recently, reproductive and neurobehavioral effects of bisphenol A (BPA) have been documented, and thus a review was requested for BPA management direction by the government. Therefore, this study was performed to establish a Korean tolerable daily intake (TDI) for BPA. An expert committee, consisting of specialists in fields such as toxicology, medicine, pharmacology, and statistics, was asked to evaluate BPA health based guidance values (HbGVs). Although many toxicological studies were reviewed to select a point of departure (POD) for TDI, rat and mouse reproductive studies by Tyl et al. (2002, 2006), which were performed according to GLP standards and OECD guidelines, were selected. This POD was the lowest value determined from the most sensitive toxicological test. The POD, a NOAEL of 5 mg/kg bw/day, was selected based on its systemic toxicity as critical effects. An uncertainty factor of 100 including interspecies and intraspecies differences was applied to calculate the TDI. According to the evaluation results, a TDI of BPA for Korean was suggested at 0.05 mg/kg bw/day. In addition, the BPA exposure level based on food consumption by the Korean population was estimated as 1.509 ${\mu}g/kg$ bw/day, and the HI was evaluated at 0.03 when the TDI of 0.05 mg/kg bw/day was applied. This HI value of 0.03 indicated that hazardous effects would not be expected from BPA oral exposures. Although highly uncertain, further studies on low dose neurobehavioral effects of BPA should be performed. In addition, it is recommended that the 'as low as reasonably achievable' (ALARA) principle be applied for BPA exposure from food packaging materials in newborn infants and children.

의류관련정보를 제공하는 웹사이트 평가요인에 관한 연구 (A Study on the Evaluation Factors of Websites that Offer Clothing and Ornament Related Information)

  • 박길순;류신아
    • 복식
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    • 제52권7호
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    • pp.71-85
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    • 2002
  • The purpose of this study is (1) to research on the diverse evaluation criteria suggested in the existing literatures, selected the contents of the evaluation according to the evaluation factors, and examined whether they are appropriate for the evaluation of websites that offer Clothing and Ornament related information through reliability analysis - all to set the evaluation criteria for the websites that acquire data. In addition. (2) contents of evaluation which are deemed important by the users and developers were compared and recommended as the detailed evaluation contents according to evaluation factors. The results of this study were as follows. 1. The evaluation factors for the fashion websites that provide Clothing and Ornament related information were selected as follows: contents of the information(11 contents of evaluation), ease of use(12), screen design(10), accessibility(9), sensitive enjoyment(4), scope of information use(3), purpose(1), and target user(1). As result of reliability analysis. Cronbach's a contents of the information (0.76), ease of use (0.77), screen design (0.85), accessibility (0.81), sensitive enjoyment (0.71), and scope of information use (0.52). 2. When the level of importance for the detailed evaluation contents was examined from the user and developer point of view, recency of information. rapid speed for the websites access. fast loading of webtext and fast transmission speed topped the list as first, second and third places.

LC-MS/MS를 이용한 건강기능식품 내 항히스타민 20종 동시분석법 개발 (Development of a LC-MS/MS method for simultaneous analysis of 20 antihistamines in dietary supplements)

  • 도정아;김정연;최지연;이지현;김형주;노은영;조소현;윤창용;김우성
    • 분석과학
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    • 제28권2호
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    • pp.86-97
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    • 2015
  • Recently, the consumption of dietary supplements has increased because of people’s greater interest in health. Unfortunately, the sales of dietary supplements containing unauthorized substances such as drugs have also increased. We developed a rapid, accurate method for the simultaneous determination of antihistamines using liquid chromatography tandem mass spectrometry with a multiple reaction monitoring mode. The limit of detection (LOD) and limit of quantification (LOQ) of the instrument used in this method were in the ranges 0.0003-0.3 and 0.0009-0.6 µg mL−1, respectively. The linearity of the method was > 0.99. The precision levels of the method were 0.1-9.8% (intra-day) and 0.3-9.6% (inter-day), and the levels of accuracy of the method were 82.7-115.0% (intra-day) and 84.3-113.0% (inter-day). The mean of recovery of the method was in the range of 83.9-117.9% and the RSD of the stability was less than 5.9%.

Development and validation of an analytical method for the quantification of 2,6-diisopropylnaphthalene in agricultural products using GC-MS/MS

  • Lee, Han Sol;Park, Ji-Su;Lee, Su Jung;Shin, Hye-Sun;Chung, Yun mi;Choi, Ha na;Yun, Sang Soon;Jung, Yong-hyun;Oh, Jae-Ho
    • 분석과학
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    • 제34권1호
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    • pp.1-8
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    • 2021
  • An analytical method was developed and optimized for the quantification of a plant growth regulator, 2,6-diisopropylnaphthalene (2,6-DIPN), in agricultural products using gas chromatography-tandem mass spectrometry. The samples were extracted, partitioned, and were purified using a Florisil® cartridge. To validate the analytical method, its specificity, linearity, limit of detection (LOD) and limit of quantification (LOQ) of the instrument, LOQ of the analytical method (MLOQ), accuracy, and repeatability were considered. The method displayed excellent results during validation, and is suitable for the determination and quantification of the low residual levels of the analyte in the agricultural samples. All of the results with the optimized method were satisfactory and within the criteria ranges requested in the Codex Alimentarius Commission guidelines and the Ministry of Food and Drug Safety guidelines for pesticide residue analysis. The developed method is simple and accurate and can be used as a basis for safety management of 2,6-DIPN.

엔지니어기반 전산시스템을 적용한 철근콘크리트 기존 건축물의 내진성능평가 (Seismic Performance Evaluation of Existing Buildings with Engineer-oriented Computerized System)

  • 황선우;김동연;김태진;김경태
    • 한국지진공학회논문집
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    • 제21권2호
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    • pp.105-114
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    • 2017
  • Nonlinear analysis for seismic performance evaluation of existing building usually takes 4~5 times more than linear analysis based on KBC code. To obtain accurate results from the nonlinear analysis, there are a lot of things to be considered for nonlinear analysis modeling. For example, reinforcing layout, applied load and seismic details affect behavior of structural members for the existing building. Engineer-oriented computerized system was developed for engineers to evaluate effective seismic performance of existing buildings with abiding by seismic design principles. Using the engineer-oriented program, seismic performance evaluation of reinforced concrete building was performed. Nonlinear hinge properties were applied with real time multiple consideration such as section layout, section analysis result, applied load and performance levels. As a result, the building was evaluated to satisfy LS(Life Safety) performance level. A comparison between engineer-oriented and program-oriented results is presented to show how important the role of structural engineer is for seismic performance evaluation of existing buildings.

루츠타입 진공펌프의 동특성 평가 (Evaluation of Rotor Dynamic Characteristic of Roots Type Vacuum Pump)

  • 이종명;김용휘;하정민;구동식;황호준;최병근
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2011년도 추계학술대회 논문집
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    • pp.264-270
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    • 2011
  • The goal of this study is a stability evaluation through eigenvalue and rotor dynamics analysis of the vacuum pump. The vacuum pump used is a roots type pump, one of the dry middle vacuum pumps, is necessary at the procedure to produce semiconductor and display. The eigenvalue evaluation is solved by numerical analysis through using Modal test and 2D 3D models. Both the experiment and the analysis result are similar, the analysis result using 2D is more oculate the 3D model comparing with test result. So rotor dynamic evaluation is performed through using 2D model. Rotor dynamic evaluation used the campbell diagram and root locus map which were acquired by complex eigenvalue analysis. And we checked minimum clearance of vacuum pump composition between two rotors through unbalance response analysis. Thus, vacuum pump, the target object of this study, was evaluated to be operated stably.

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정보영재를 위한 온라인 콘텐츠 평가 준거 개발 (Development of On-line Content Evaluation Standards for Informatics Gifted Students)

  • 김용;김정훈
    • 한국콘텐츠학회논문지
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    • 제10권9호
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    • pp.487-495
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    • 2010
  • 본 연구는 온라인 정보영재 교육의 질적 제고를 위해 온라인 콘텐츠 평가 준거를 제시하였다. 선행연구를 통해 나타난 정보영재의 특징과 사고양식, 학습양식의 특성을 기반으로 정보영재를 위한 온라인 콘텐츠 평가 준거를 개발하였다. 개발된 평가 준거는 정보영재 전문가를 대상으로 문항 타당성 검사를 진행하였다. 분석 결과 전체 문항의 신뢰도는 .94로 신뢰롭게 나타났다. 그리고 문항 특성 부분인 변별도는 .53~.83이었고, 난이도에서도 만족할만한 결과 값을 보여주었다. 개발된 정보영재를 위한 온라인 콘텐츠 평가 준거는 '재능개발', '상호작용' 등 5개 평가 영역, 11개 평가 요인, 40개 평가 문항으로 구성하였다. 본 연구에서 제시한 평가 준거는 정보영재 온라인 콘텐츠 개발을 위한 가이드라인 및 온라인 교재 선택에 도움을 줄 수 있을 것으로 기대된다.

중등학교 가정과 교육의 실기평가 실태에 관한연구 (A Study on the Practical Skill Evaluation in Secondary School Home Economics Education)

  • 이지향;신상옥
    • 한국가정과교육학회지
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    • 제2권1호
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    • pp.45-90
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    • 1990
  • This study aims finding a desirable practical skill evaluation practice evaluation method and then improving student’s learning effect by analyzing the present state and the methods of practical skill evaluation in middle-high schools home economics education. Investigated persons are 250 of high schools home economics thachers(125) and middle schools home economics teacher(125) in Seoul, who are choosen by means of random sampling. The items analysis of questionnaires was performed by means of SPSS(Statistical Package for Social Science). The investigator analyzed their responses to the questionnaires according to teachers’ages, school careers, majors, places of employment, school years in charge. The results are marked with percentage and the significance level is verified by means of Chi-square(X$\^$2/) analysis method, when necessary. This thesis handles practical skill evaluation of general practice units, of clothing and textile unit, and of nutrient and food unit. The results obtained from the items analysis are as follows; I. Results of the items analysis. A. Practical skill evaluation of general units. 1. The motivation and accomplishment feeling of students are most frequently considered as the aims of practical skill evaluation, but the results of practical skill evaluation are, by contraries, most infrequently considered as improvement materials. 2. A greatest number of teachers make together with their colleagues an annual plan for practical skill evaluation an inform students of the concrete information of the test, but perform respectively practical skill evaluation, using 5 steps method. 3. The percentage that teachers majoring in home economics education as compared with others lay the similar stresses on the preparation processes, attitudes, and results of students is very high.

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델파이 기법과 AHP를 이용한 중력식 사방댐 준설 평가지표 및 조사야장 개발 (Development of Indicators for Dredging Evaluation and Form on Erosion Control Dam Using the Delphi Technique and AHP Analysis)

  • 서준표;이창우;우충식;이헌호
    • 한국환경복원기술학회지
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    • 제17권6호
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    • pp.1-15
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    • 2014
  • A dredging on erosion control dam has been enforced without evaluation the factors that affect the dredging. In addition, there is the negative effect much more than positive effect by dredging on erosion control dam. Therefore, this study was carried out to develop evaluation indicators and to suggest fieldbook in order to determine whether sand deposits at erosion control dam should be dredged up or not. The most important six evaluation indicators that can decide to dredge up at erosion control dam were obtained from three round delphi technique and were selected in the following order: the current sand deposit ratio(0.339), existence of cultivated land and house downstream(0.276), the slope of streambed(0.162), the amount of movable soil and gravel(0.118), the history of any disasters(0.063), the basin area(0.043). The weighted score for each evaluation indicator were acquired from AHP analysis with respect to the degree of importance and then the modified weighted score for actual measurements were classified as three categories: large(2.53), medium(1.60) and small(1.01). Based on delphi technique, erosion control dam dredging evaluation fieldbook introduced the four evaluation indicators out of the total six evaluation indicators and two low effected evaluation indicators were excluded. This results showed that the values for reliability analysis and consistency ratio were acceptable.

Evaluation of the Middle Part of the Nuclear Fuel Cycle

  • Kovac, Michal
    • Nuclear Engineering and Technology
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    • 제48권1호
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    • pp.169-174
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    • 2016
  • This article describes a comprehensive methodology for the evaluation of the middle part of nuclear fuel cycles. Evaluation of fuel cycles is basically divided into two parts. The first comprises nuclear calculation, i.e., creation of the strategy for nuclear fuel reloading and core design calculations. The second part is the business-economic evaluation of the selected reloading strategy, which can be done either by financial analysis or economic analysis. The financial analysis incorporates the perspectives of a company while the economic analysis can be used primarily by national economists or politicians. This methodology was applied to a case study that is focused on impacts of switching from a 12-month to an 18-month fuel cycle strategy for Water-Water Energetic Reactor (VVER)-1000 reactors.