• Journal of Pharmacopuncture
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• v.18 no.1
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• pp.63-71
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• 2015

Objectives: This study was carried out to analyze the single-dose toxicity of Eun-Bi San pharmacopuncture injected into the muscle of Sprague-Dawley (SD) rats. Methods: All experiments were performed at Biotoxtech, an institution certified to conduct non-clinical studies under the Good Laboratory Practice (GLP) regulations. Six week old SD rats reared by ORIENTBIO were chosen for this pilot study. The reason SD rats were chosen is that they have been widely used in safety tests in the field of medicine, so the results can be easily compared with many other databases. The Eun-Bi San pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (KPI, K-GMP). The constituents of the Eun-Bi San pharmacopuncture are Angelicae gigantis radix, Strychni semen and Glycyrrhizae radix. These were extracted at low temperature and low pressure in an aseptic room at the KPI. Doses of Eun-Bi San pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. This study was performed under the approval of the Institutional Animal Ethics Committee of Biotoxtech Co., Ltd. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To determine if abnormalities existed in any organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The results of this study suggest that treatment with Eun-Bi San pharmacopuncture is relatively safe and that its clinical use may be beneficial. Further evaluations and studies on this subject will be needed to provide more concrete evidence in support of these conclusions.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.2
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• pp.333-337
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• 2010

A 51-year-old man developed diplopia while driving. The brain CT film demonstrated a hemorrhage in the left midbrain and thalamus. On our first diagnosis after 8 days from onset, partial ptosis and limitation of adduction in the left eye were detected. We evaluated that the patinet's digestive system was weak, so that treated the patient with Bojungikki-tang and Sa-am acupuncture Bi-Jung-Geouk(脾正格). As a result, limitation of adduction was recovered to about 90% of normal range and Ptosis was recovered just likely with the normal eye.

• The Journal of Internal Korean Medicine
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• v.13 no.2
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• pp.141-155
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• 1992

This study has been carried out to investigate the cause symptom and treatment of Poong-On(風溫) by referring to 29 leteratures. The results were obtained as follows; 1. The factors causing Poong-On(風溫) is wind and heat. 2. The symptom of Poong-On(風溫) is as follows. fever, chilling, cough, sweating sign, chest discomfort, thirst, Doo Chang Wan Bi(頭脹脘痺), Yang Maeg Boo Hwal(陽脈浮滑), Eum Maeg Yoo Yak(陰脈濡弱), Seol Tae Baek Bak(舌苔白薄). 3. The treatment-method of Poong-On(風溫) is as follows. Sin Ryang Hae Pyo(辛凉解表), San Poong Han Ii Rae Pyo(散風寒以解表), Seol Yeol Hwa Eum(泄熱和陰), So Sul Ii Hae Pyo(疏泄以解表). 4. The treatment-herbs of Poong-On(風溫) is as follows, Eun Gyo San(銀翹散), Ma Haeng Gam Sug Tang(麻杏甘石湯), Jo Wee Sung Gi Tang(調胃承氣湯), An Goong Woo Hwang Hwan(安宮牛黃丸), Seo Gag Ji Hwang Tang(犀角地黃湯), Baek Ho Tang(白虎湯), Sa Sam Maeg Moon Dong Tang(沙蔘麥門冬湯), Ga Gam Bok Maeg Tang(加減伏脈湯), Saeng Maeg San(生脈散).

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.01a
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• pp.341-344
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• 2021

현재 우리나라는 소프트웨어(SW)에 대한 관심 증가에도 불구하고 초등 소프트웨어 교육을 위한 표준 교육 계획이 마련되지 않아 체계적인 교육을 통한 컴퓨팅 사고력 배양이 어려운 상황이다. 따라서 본 논문에서는 언플러그드 활동을 통해 컴퓨팅 사고력을 증진시킨 후 이를 바탕으로 코딩 문제해결능력을 향상시킬 수 있는 교육 콘텐츠의 필요성에 대해 인식하였고, 언플러그드와 블록 코딩을 연계한 초등 소프트웨어 교육 계획을 제안한다. 교육 계획은 소프트웨어에 대한 접근, 언플러그드 교육을 통한 컴퓨팅 사고력 향상, 코딩 교육을 통한 문제 해결 능력 향상 과정 등 총 3단계로 구성되었다. 개발된 콘텐츠의 매 주제는 언플러그드 교육과 코딩 교육이 서로 연계되도록 구성하여, 코딩 개념 학습 및 이와 연관된 컴퓨팅 사고력 향상 후, 학습된 내용을 코딩 과정에서 실체화 하도록 하여 응용력이 배양될 수 있도록 하였다.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.1148-1159
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• 2021

Objectives: This study investigated the effect of combined Korean medical treatment and antibiotics on a patient diagnosed with nontuberculous mycobacterial lung disease. Methods: The patient had been treated with antibiotics since July 2020 concurrently with Maekmoondong-tang, Banhasasim-tang, Gwakhyangjunggi-san and Bojungikgi-tang. The improvement of symptoms was evaluated using scores for the numerical rating scale (NRS), the Medical Research Council (MRC) dyspnea scale, C-reactive protein (CRP) levels, and computed tomography (CT). Results: Following treatment, the NRS, MRC dyspnea scale and CT images significantly improved. Also, CRP levels remained in the normal range during treatment. Conclusions: Traditional Korean medical treatment combined with antibiotics could be effective for treating patients with nontuberculous mycobacterial lung disease.

• Journal of the Semiconductor & Display Technology
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• v.22 no.4
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• pp.99-102
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• 2023

In this paper, the system is proposed and implemented to share the part number, the part name, and the vehicle type through the improvement sharing bulletin board for automobile repair and maintenance. And when photos of damage parts are uploaded to the system, the system analyzes it using a deep learning model to analyze whether it is damaged and automatically classify the type of damage. By providing repair and maintenance quotes for a significant part, the system provides economically repaired by providing comparative adjustment information on repair costs to drivers who are particularly concerned about the market prices of parts and maintenance services. Through the existing bulletin board, you can exchange and share information about parts by sharing various information on repair and maintenance. This paper provides in detail the average market price per type of damage during automobile repair and maintenance, helping drivers who do not know the details of parts and maintenance services to receive reasonable quotes by providing price information.

• Korean Journal of Pharmacognosy
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• v.23 no.3
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• pp.158-170
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• 1992

The studies were conducted to investigate the combined effects of several combined preparation of crude drugs and mitomycin C(MMC). The combined effects on the proliferation of Molt-4 cells and activation of human lymphocytes were estimated by MTT colorimetric assays. The drugs itself enhanced the proliferation of Molt-4, but the inhibitory action of MMC was not affected by the combined treatment of the drugs and MMC. Among 9 kinds of the drugs, Sip Jeon Dae Bo Tang(SDT), Saeng Maek San(SMS) and Kwi Bi Tang(KBT) did not inhibit the action of MMC, but activated lymphocytes. When the mice were treated by MMC, the number of leukocytes was decreased significantly at the 1st day, but recovered at the 7th day. In the groups of MMC treated with SDT or KBT, the number of leukocytes was increased significantly than the group of MMC treated only at the 3rd day. The combined treatment of SDT, SMS and MMC retained the body weight of mice at the level of normal mice. The SDT, SMS and KBT did not change the number of plaque forming cells(PFC) and the proliferation of T cells. The combined treatment of SDT and MMC increased the number of PFC significantly than the MMC treated group. The combined treatment of SDT, SMS, KBT and MMC increased the T cell proliferation significantly than the MMC treated group. In conclusion, it is suggested that SDT, SMS and KBT can recover the side effects of MMC, such as weight loss, leukopenia and immunosuppression, without any intercalating the anti-proliferative action of MMC in vivo.