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Radiation Dose during Transmission Measurement in Whole Body PET/CT Scan (전신 PET/CT 영상 획득 시 투과 스캔에서의 방사선 선량)

  • Son Hye-Kyung;Lee Sang-Hoon;Nam So-Ra;Kim Hee-Joung
    • Progress in Medical Physics
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    • v.17 no.2
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    • pp.89-95
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    • 2006
  • The purpose of this study was to evaluate the radiation doses during CT transmission scan by changing tube voltage and tube current, and to estimate the radiation dose during our clinical whole body $^{137}Cs$ transmission scan and high quality CT scan. Radiation doses were evaluated for Philips GEMINI 16 slices PET/CT system. Radiation dose was measured with standard CTDI head and body phantoms in a variety of CT tube voltage and tube current. A pencil ionization chamber with an active length of 100 mm and electrometer were used for radiation dose measurement. The measurement is carried out at the free-in-air, at the center, and at the periphery. The averaged absorbed dose was calculated by the weighted CTDI ($CTDI_w=1/3CTDI_{100,c}+2/3CTDI_{100,p}$) and then equivalent dose were calculated with $CTDI_w$. Specific organ dose was measured with our clinical whole body $^{137}Cs$ transmission scan and high quality CT scan using Alderson phantom and TLDs. The TLDs used for measurements were selected for an accuracy of ${\pm}5%$ and calibrated in 10 MeV X-ray radiation field. The organ or tissue was selected by the recommendations of ICRP 60. The radiation dose during CT scan is affected by the tube voltage and the tube current. The effective dose for $^{137}Cs$ transmission scan and high qualify CT scan are 0.14 mSv and 29.49 mSv, respectively. Radiation dose during transmission scan in the PET/CT system can measure using CTDI phantom with ionization chamber and anthropomorphic phantom with TLDs. further study need to be peformed to find optimal PET/CT acquisition protocols for reducing the patient exposure with same image qualify.

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Verification of Radiation Therapy Planning Dose Based on Electron Density Correction of CT Number: XiO Experiments (컴퓨터영상의 전자밀도보정에 근거한 치료선량확인: XiO 실험)

  • Choi Tae-Jin;Kim Jin-Hee;Kim Ok-Bae
    • Progress in Medical Physics
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    • v.17 no.2
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    • pp.105-113
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    • 2006
  • This study peformed to confirm the corrected dose In different electron density materials using the superposition/FFT convolution method in radiotherapy Planning system. The experiments of the $K_2HPO_4$ diluted solution for bone substitute, Cork for lung and n-Glucose for soft tissue are very close to effective atomic number of tissue materials. The image data acquisited from the 110 KVp and 130 KVp CT scanner (Siemes, Singo emotions). The electron density was derived from the CT number (H) and adapted to planning system (Xio, CMS) for heterogeneity correction. The heterogeneity tissue phantom used for measurement dose comparison to that of delivered computer planning system. In the results, this investigations showed the CT number is highly affected in photoelectric effect in high Z materials. The electron density in a given energy spectrum showed the relation of first order as a function of H in soft tissue and bone materials, respectively. In our experiments, the ratio of electron density as a function of H was obtained the 0.001026H+1.00 in soft tissue and 0.000304H+1.07 for bone at 130 KVp spectrum and showed 0.000274H+1.10 for bone tissue in low 110 KVp. This experiments of electron density calibrations from CT number used to decide depth and length of photon transportation. The Computed superposition and FFT convolution dose showed very close to measurements within 1.0% discrepancy in homogeneous phantom for 6 and 15 MV X rays, but it showed -5.0% large discrepancy in FFT convolution for bone tissue correction of 6 MV X rays. In this experiments, the evaluated doses showed acceptable discrepancy within -1.2% of average for lung and -2.9% for bone equivalent materials with superposition method in 6 MV X rays. However the FFT convolution method showed more a large discrepancy than superposition in the low electron density medium in 6 and 15 MV X rays. As the CT number depends on energy spectrum of X rays, it should be confirm gradient of function of CT number-electron density regularly.

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Performance Measurement of Siemens Inveon PET Scanner for Small Animal Imaging (소동물 영상을 위한 Siemens Inveon PET 스캐너의 성능평가)

  • Yu, A-Ram;Kim, Jin-Su;Kim, Kyeong-Min;Lee, Young-Sub;Kim, Jong-Guk;Woo, Sang-Keun;Park, Ji-Ae;Kim, Hee-Joung;Cheon, Gi-Jeong
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.145-152
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    • 2010
  • Inveon PET is a recently developed preclinical PET system for small animal. This study was conducted to measure the performance of Inveon PET as recommended by the NEMA NU 4-2008. We measured the spatial resolution, the sensitivity, the scatter fraction and the NECR using a F-18 source. A 3.432 ns coincidence window was used. A $1\;mm^3$ sized F-18 point source was used for the measurement of spatial resolution within an energy window of 350~625 keV. PET acquisition was performed to obtain the spatial resolution from the center to the 5 cm offset toward the edge of the transverse FOV. Sensitivity, scatter fraction, and NECR were measured within an energy window of 350~750 keV. For measuring the sensitivity, a F-18 line source (length: 12.7 cm) was used with concentric 5 aluminum tubes. For the acquisition of the scatter fraction and the NECR, two NEMA scatter phantoms (rat: 50 mm in diameter, 150 mm in length; mouse: 25 mm in diameter, 70 mm in length) were used and the data for 14 half-lives (25.6 hr) was obtained using the F-18 line source (rat: 316 MBq, mouse: 206 MBq). The spatial resolution of the F-18 point source was 1.53, 1.50 and 2.33 mm in the radial, tangential and axial directions, respectively. The volumetric resolution was $5.43\;mm^3$ in the center. The absolute sensitivity was 6.61%. The peak NECR was 486 kcps @121 MBq (rat phantom), and 1056 kcps @128 MBq (mouse phantom). The values of the scatter fraction were 20.59% and 7.93% in the rat and mouse phantoms, respectively. The performances of the Inveon animal PET scanner were measured in this study. This scanner will be useful for animal imaging.

Stereoscopic depth of surfaces lying in the same visual direction depends on the visual direction of surface features (표면 요소의 시선방향에 의한 동일시선 상에 놓여있는 표면의 입체시 깊이 변화)

  • Kham Keetaek
    • Korean Journal of Cognitive Science
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    • v.15 no.4
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    • pp.1-14
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    • 2004
  • When two objects are tying in the same visual direction there occurs abrupt depth change between two objects, which is against the assumption of the computational model for stereopsis on the surfaces in a natural scene. For this reason, this stimulus configuration is popularly used in the studies for the effectiveness of the constraints employed in the computational model. Contrary to the results from two nails (or objects) tying in the same visual direction, the two different surfaces from random-dot stereogram (RDS) in the same situation can be seen simultaneously in the different depth. The seemingly contradictory results between two situations my reflect the different strategies imposed by binocular mechanism for each situation during binocular matching process. Otherwise, the surfaces tying in the same visual direction is not equivalent situation to two objects tying in the same visual direction with regards to matching process. In order to examine above possibilities, the stereoscopic depth of the surface was measured after manipulating the visual direction of the surface elements. The visual direction of each dot pair from different surfaces in RDS (in Experiment 1) or the visual direction of line (hawing rectangle with regard to that of the vertical line (in Experiment 2) was manipulated. The stereoscopic depth of the surface was found to be varied depending on visual direction of the surface elements in both RDS and line hawing stimulus. Similar to the results from two nails situation depth of the surface was greatly reduced when each surface element was tying in the same visual direction as that of the other surface element or the other object. These results suggest that binocular mechanism imposes no different strategy in resolving correspondence problem in both two objects and two surfaces situation. And the results were discussed in the context of usefulness of the constraints employed in the computational model for stereopsis.

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Interactions among Carbon Isotope Discrimination, Water Use Efficiency and Nitrogen Nutrition in Wheat and Barley (밀과 보리에 있어서 탄소동위원소차별, 수분이용효율, 질소영양간의 상호작용)

  • Young Kil, Kang;Richard A., Richards;Anthony G., Condon
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.41 no.3
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    • pp.318-331
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    • 1996
  • Large and small seeds (44 and 22 mg per caryopsis) of a spring wheat (cv. Kulin) and a spring barley (cv. Skiff) were sown at two nitrogen rates (equivalent to 10 and 32 g m$^{-2}$ ) in well-watered pots under outdoor conditions to determine the effects of seed size and nitrogen (N) nutrition on water use efficiency (WUE) and carbon isotope discrimination ($\Delta$) and to evaluate interaction among $\Delta$, WUE and N nutrition in wheat and barley. Barley produced, on average, 105% more biomass (root+shoot dry weight) than wheat at stem elongation because of early vigor. By anthesis this difference had disappeared as wheat had 16% more biomass than barley which headed 3 days earlier. Compared to plants grown from small seed, plants grown from large seed had much greater biomass in wheat than in barley at stem elongation and anthesis. Higher N nutrition increased average biomass of wheat and barley by 40 and 31%, respectively, at anthesis. Barley had 35 and 20% greater WUE (biomass gained/transpiration) than wheat at stem elongation and anthesis, respectively, and 2.0 to 3.6% lower $\Delta$ in aboveground shoots depending on growth stages and plant parts than wheat which had a greater stomatal conductance than barley. Seed size had a variable effect on WUE and did not affected $\Delta$ values. Water use efficiency was not affected by N rate at stem elongation in wheat and barley whereas WUE was increased 2 and 7%, respectively, in wheat and barley at anthesis with increasing N from 10 to 32 g m$^{-2}$ . High N plants had about 2.5% lower $\Delta$ values regardless of growth stages than low N plants across species and seed sizes. Carbon isotope discrimination was negatively correlated with WUE at anthesis but not at stem elongation.

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Eutrophication in the Downstream of Nakdong River (낙동강 하류역의 부영양화현상에 관한 연구)

  • CHOI Young-Chan;PARK Chung-Kil
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.19 no.4
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    • pp.339-346
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    • 1986
  • A study on eutrophication in the downstream of the Nakdong River was conducted from October 1983 to September 1984. Nutrients concentration of the samples in this area was usually high and the nitrogen ratio to the phosphorus was as very high as $63.5{\sim}119.6$. The concentration of nutrients was in the range of $0.22{\sim}173{\mu}g-at/l$ for ammonia nitrogen, $26.7{\sim}187{\mu}g-at/l$ for nitrate nitrogen, $1.07{\sim}8.22{\mu}g-at/l$ for nitrite nitrogen, $58.7{\sim}231{\mu}g-at/l$ for total inorganic nitrogen and $0.44{\sim}4.43{\mu}g-at/l$ for phosphate phosphorus. The concentration of chlorophyll-a was in the range of $1.8{\sim}75.2\;mg/m^3$. Correlationship between concentration of nutrients and chlorophyll-a was not found. The concentrations of total suspended solid were in the range of $10.7{\sim}45.9\;ppm$, and $16.2{\sim}35.2\%$ of the total suspended solid was consisted of volatile suspended solid. According to the state of lacustrine nutrition, the state of the downstream of Nakdong River was equivalent to the eutrophication state in term of chlorophyll-a and inorganic nitrogen, and mid-nutritional state in term of phosphate.

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STUDIES ON THE EXTRACTION OF SEAWEED PROTEINS 4. Precipitation Conditions and Nutritional Evaluation of Isolated Seaweed proteins (해조단백질 추출에 관한 연구 4. 추출단백질의 심전조건 및 영양적 평가)

  • WOO Soon-Im;RYU Hong-Soo;LEE Kang-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.12 no.4
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    • pp.225-234
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    • 1979
  • For the effective utilization of diverse and abundant resource of seaweeds in Korea as a food protein supplment, extraction conditions of water, salt, and alkali soluble proteins were investigated in previous work(Ryu and Lee, 1977: Lee et al., 1977: Lee et al., 1978). The present study as a part of the serial work was thus aimed to find the conditions of isolation and purification of extracted proteins, and to evaluate the nutritional quality of the isolated seaweed proteins in terms of amino acid composition, chemical score, protein score, modified essential amino acid index(MEAAI), and in vitro digestibility presented as pepsin-pancreatin digest residue index (PPDRI). As for the isolation of extracted proteins, TCA treatment was more effective for the proteins from rhodophyceae and Chlorophyceae while the precipitation at isoelectric point was more desirable for Phaeophyceae proteins. In amino acid composition, water soluble protein fraction was superior to the other fractions in Porphyra suborbiculata whereas both water and alkali soluble fractions seemed to bo more benefitial for Enteromorpha linza and Ulva pertusa; the extraction with alcohol-alkali mixed solvent for Undaria pinnatifida and Sargassum fulvellum. Glutamic acid and aspartic acid content was particularly high in all protein fractions examined. The total amino acid content of Porphyra suborbiculata and Enteromorpha linza was almost equivalent to that of dried whole egg although the essential amino acid content was lower. A comparative analysis was made on the inedexes between raw seaweed powder and isolated protein. Chemical score of Porphyra suborbiculata and Ulva pertusa was approximately 35 and 56 in cafes of raw powder and isolated protein respectively while only 10 to 16 for raw powder of Undaria pinnatifida and Sargassum fulvellum and 30 to 35 for their isolated proteins. Protein score of all isolated proteins was in the range of 63 to 73 which indicates that isolated protein would be mere valuable than the fern of raw seaweed powder. Digestibility by means of PPDRI was found to be extremely low in case of raw powder but it could be doubled in case of isolated protein yielding 67 to 70 for Porphyra suborbiculata and Ulva pertusa.

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Groundwater-Stream Water Interaction Induced by Water Curtain Cultivation Activity in Sangdae-ri Area of Cheongju, Korea (청주 상대리지역에서 수막재배가 지하수-하천수 상호작용에 미치는 영향)

  • Moon, Sang-Ho;Kim, Yongcheol;Jeong, Youn-Young;Hwang, Jeong
    • Economic and Environmental Geology
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    • v.49 no.2
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    • pp.105-120
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    • 2016
  • Most of riverside in Korea, in case of application of water curtain cultivation (WCC) technique, has been inveterately suffering from the gradual drawdown of groundwater level and related shortage of water resources during the WCC peak time. We believe that the water resources issue in these riverside areas can be effectively solved when the interaction between groundwater and nearby surface water is well understood. To investigate the connection between stream and ground water, and the influence of stream water on the nearby aquifer, this study examined the water temperature and oxygen and hydrogen stable isotopic compositions. The study area is well-known strawberry field applying the WCC technique in Sangdae-ri, Gadeok-myon, Cheongju City, and the sampling was done from February 2012 through June 2014 for stream and ground water. Some groundwater wells near stream showed big temporal variations in water temperature, and their oxygen and hydrogen stable isotopes showed similar compositions to those of adjacent stream water. This indicates that the influence of stream water is highly reflected in the stable isotopic composition of groundwater. Four cross-sectional lines from stream to hillside were established in the study area to determine the spatial differences in water quality of wells. At the late stage of WCC in February to March, groundwater of wells in line with short cross-sectional length showed the narrow range of isotopic compositions; however, those in the long cross-sectional line showed a wide compositional range. It was shown that the influence of the stream water at the late WCC stage have reached to the distance of 160 to 165 m from stream line, which is equivalent to the whole length and one-third point in each short and long cross-sectional line, respectively. Therefore, the wide compositional range in the long cross-sectional lines was not only due to the influence of stream water, but apparently resulted from the change of relative impact of each groundwater supplying from two or more aquifers. In view of stable isotopic compositions, there seems to be three different aquifers in this study area, which is competing for dominance of water quality in wells at each period of WCC.

Measurement of Operator Exposure During Treatment of Fungicide Difenoconazole on Grape Orchard (포도 과수원에서 살균제 Difenoconazole의 농작업자 노출량 측정)

  • Cho, ll Kyu;Park, Joon Seong;Park, So Hyun;Kim, Su Jin;Kim, Back Jong;Na, Tae Wong;Nam, Hyo Song;Park, Kyung Hun;Lee, Jiho;Kim, Jeong-Han
    • Korean Journal of Environmental Agriculture
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    • v.35 no.4
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    • pp.286-293
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    • 2016
  • BACKGROUND: 18% of difenoconazole+iminoctadin triacetate microemulsion (3%+15%) formulation were mixed and sprayed as closely as possible to normal practice on the ten of farms located in the Youngju of South Korea. Patches, cotton gloves, socks, masks and XAD-2 resin were used to measure the potential exposure for applicators wearing standardized whole-body outer and inner dosimeter (WBD). This study has been carried out to determine the dermal and inhalation exposure to difenoconazole during preparation of spray suspension and application with a power sprayer on a grape orchard. METHODS AND RESULTS: A personal air monitor equipped with an air pump IOM sampler and cassette and glass fiber filter were used for inhalation exposure. The field studies were carried out in a grape orchard. The temperature and relative humidity were monitored with a thermometer and a hygrometer. Wind speed was measured using a pocket weather meter. All mean field fortification recoveries were between 97.3% and 119.6% in the level of 100 LOQ (limit of quantification) while the LOQ for difenoconazole was $0.025{\mu}g/mL$ using HPLC-UVD. The arms exposure to difenoconazole for the mixer/loader (0.0794 mg) was higher than other body parts (head, hands, upper body, legs). The exposure to difenoconazole in the legs for applicator (3.78 mg) was highest in the parts of body. The dermal exposure for mixer/loader and applicator were 0.02 and 2.28 mg on a grape orchard, respectively. The inhalation exposure during application was estimated as 0.02 mg. The ratio of inhalation exposure to dermal exposure was equivalent to 0.9% of the dermal exposure. CONCLUSION: The inhalation exposure for applicator indicated $18.8{\times}10^{-3}mg$, which was level of 0.9% of the dermal exposure (2.28 mg). Operator exposure (0.004 mg/kg bw/day) to difenoconazole during treatment for grape is calculated as 2.5% of the established AOEL (0.16 mg/kg bw/day).

Study on verification of various national standards regarding phthalate testing in industrial products (공산품 중 프탈레이트류 함유량 분석법에 관한 국내외 표준의 검증 연구)

  • Song, Moon-Hwan;Cho, Young-Dal;Choe, Eun-Kyung;Myoung, Young-Chan
    • Analytical Science and Technology
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    • v.25 no.3
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    • pp.178-189
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    • 2012
  • As phthalates classified as toxic to reproduction category 2 and endocrine disrupting chemicals were more strictly regulated as Substances of Very High Concern (SVHC) for authorization in under EU REACH and considered as priority substances in RoHS II, standardization of phthalate testing method is now being proposed in IEC 62321 of IEC TC 111 and the 2nd revision of KS M 1991 is also finished. In order to assist standardization activities related to phthalating testing, solvent extraction part of existing national standards were compared and verified. Recovery of DEHP (diethylhexyl phthalate) from PVC (polyvinyl chloride) by Soxhlet extraction increased in the order of methanol, toluene, dichloromethane and hexane from 46.9% to 95.3% as measured by GC-MS. Optimum extraction time was verified to be 6 hours using hexane. Recovery of DBP (dibutyl phthalate), BBP (butylbenzyl phthalate), and DEHP from different matrixes such as PVC, nitro cellulose, ABS (acrylonitrile butadiene styrene). and EPDM(ethylene propylene diene monomer) rubber were evaluated to be more than 90% up to 99%. The detection limits of phthalates in solvent extraction followed by GC-MS analysis were 0.08~0.3 ${\mu}g/mL$ in solution and 8~30 mg/Kg in polymeric samples. GC-MS analyses of phthalates were carried out using different solvent extraction based on the EN 14372, ASTM D 7083, Japanese test method (MHLW 0906-4) and KS M 1991, proving that equivalent recoveries ranging from 98%~99% were obtained. DBP and DEHP were detected in three consumer products such as a child toy, a power cable and manicure with the amount of 22~1,910 mg/kg.