• Animal Bioscience
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• v.36 no.4
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• pp.654-670
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• 2023

Objective: This study aimed to develop loop-mediated isothermal amplification (LAMP) combined with lateral flow dipstick (LFD) and compare it with LAMP-AGE, polymerase chain reaction (PCR), and standard Salmonella culture as reference methods for detecting Salmonella contamination in animal products and animal production environmental samples. Methods: The SalInvA01 primer, derived from the InvA gene and designed as a new probe for LFD detection, was used in developing this study. Adjusting for optimal conditions by temperature, time, and reagent concentration includes evaluating the specificity and limit of detection. The sampling of 120 animal product samples and 350 animal production environmental samples was determined by LAMP-LFD, comparing LAMP-AGE, PCR, and the culture method. Results: Salmonella was amplified using optimal conditions for the LAMP reaction and a DNA probe for LFD at 63℃ for 60 minutes. The specificity test revealed no cross-reactivity with other microorganisms. The limit of detection of LAMP-LFD in pure culture was 3×10² CFU/mL (6 CFU/reaction) and 9.01 pg/μL in genomic DNA. The limit of detection of the LAMP-LFD using artificially inoculated in minced chicken samples with 5 hours of pre-enrichment was 3.4×10⁴ CFU/mL (680 CFU/reaction). For 120 animal product samples, Salmonella was detected by the culture method, LAMP-LFD, LAMP-AGE, and PCR in 10/120 (8.3%). In three hundred fifty animal production environmental samples, Salmonella was detected in 91/350 (26%) by the culture method, equivalent to the detection rates of LAMP-LFD and LAMP-AGE, while PCR achieved 86/350 (24.6%). When comparing sensitivity, specificity, positive predictive value, and accuracy, LAMP-LFD showed the best results at 100%, 95.7%, 86.3%, and 96.6%, respectively. For Kappa index of LAMP-LFD, indicated nearly perfect agreement with culture method. Conclusion: The LAMP-LFD Salmonella detection, which used InvA gene, was highly specific, sensitive, and convenient for identifying Salmonella. Furthermore, this method could be used for Salmonella monitoring and primary screening in animal products and animal production environmental samples.

• Health Policy and Management
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• v.33 no.1
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• pp.3-18
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• 2023

Background: A chronic disease management program including patient education, recall and remind service, and reduction of out-of-pocket payment was implemented in Korea through a chronic care model. This study aimed to assess the effect of a community-based intervention program for improving medication adherence of patients with diabetes mellitus in rural areas of Korea. Methods: We applied a non-equivalent control group design using Korean National Health Insurance Big Data. Hongcheon County has been continuously adopting this program since 2012 as an intervention region. Hoengseong County did not adopt such program. It was used as a control region. Subjects were a cohort of patients with diabetes mellitus aged more than 65 years but less than 85 years among residents for 11 years from 2010 to 2020. After 1:1 matching, there were 368 subjects in the intervention region and 368 in the control region. Indirect indicators were analyzed using the difference-in-difference regression according to Andersen's medical use model. Results: The increasing percent point of diabetic patients who continuously received insurance benefits for more than 240 days from 2010 to 2014 and from 2010 to 2020 were 2.6%p and 2.7%p in the intervention region and 3.0%p and 3.9%p in the control region, respectively. The number of dispensations per prescription of diabetic patient in the intervention region increased by approximately 4.61% by month compared to that in the control region. Conclusion: The intervention program encouraged older people with diabetes mellitus to receive continuous care for overcoming the rule of halves in the community. More research is needed to determine whether further improvement in the continuity of comprehensive care can prevent the progression of cardiovascular diseases.

• Journal of the Korean Recycled Construction Resources Institute
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• v.11 no.1
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• pp.16-24
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• 2023

Coal ash generated from thermal power plants using briquettes contains Si, Al, and Fe components. These components are the main components required for the manufacture of cement clinker. In particular, Al and Fe components form the interstitial phase of cement clinker and have an important effect on the sintering of cement clinker. In this study, a large amount of coal ash was applied as a raw material for cement clinker by content, and the mineral formation process of cement clinker to which coal ash was applied was confirmed by sintering temperature. It was confirmed that the intermediate phase was generated in the sintering temperature range of 1050 ~ 1150 ℃ in the cement clinker to which a large amount of coal ash was applied. As the content of coal ash increased, the production amount of the intermediate phase increased. The phase produced by the addition of coal ash is expected to be converted to calcium silicate phase and interstitial phase and disappear above 1350 ℃. The cement clinker applied with a large amount of coal ash at 1450 ℃ formed well-developed minerals equivalent to the standard cement clinker.

• Journal of Radiation Protection and Research
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• v.9 no.2
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• pp.76-89
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• 1984

Weighted committed dose equivalents($W_T\;H_{50}$) per intake of unit activity of four nuclides-I-131, I-133, Cs-134 and Cs-137-, which was based on the concepts of ICRP Pub. 30, are calculated for adult who is 70 kg and 25 years old and, for infant who is 10 kg and 1 year old. Metabolism of iodine taken through oral or inhalation pathway is described by using the three-compartment model which consists of inorganic, thyroid and organic compartment. After intake, the amount of iodine in every compartment is calculated by solving the transfer equations among the these compartments. As soon as caesium is taken into the body, it is distributed uniformly in the body through the transfer compartment. In this case, the amount of caesium in total body is calculated by using the total body compartment model which is divided into two tissue compartments because of their different biological half-lifes of caesium in body. As a result of calculations, whether oral or inhalation pathway, the values of ($W_T\;H_{50}$) per intake of unit activity of I-131 for infants are about ten times as much as those of adults. On the other hand, for Cs-134 and Cs-137, the values of $W_T\;H_{50}$ per intake of unit activity show that, whether adults of infants, they have almost the same values.

• Journal of the Korea Institute of Building Construction
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• v.23 no.3
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• pp.221-229
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• 2023

This research aimed to conduct an empirical assessment of the penetration of chloride and sulfate ions into mortar sections using an anion exchange membrane(AEM) and laser-induced breakdown spectroscopy(LIBS). The study involved a simultaneous ion chromatography(IC) analysis and LIBS analysis performed on mortars immersed in varying concentrations of chloride and sulfate. The findings revealed that at the wavelengths specific to Chloride(837.59nm) and Sulfur(921.30nm), the LIBS intensity achieved using AEM surpassed that obtained with a paper substrate at equivalent penetration concentrations. A robust correlation was confirmed between LIBS intensity and chloride ion concentration. Furthermore, when juxtaposed with IC analysis concentration outcomes at identical depths, the AEM displayed a higher intensity. The research noted an enhancement in LIBS intensity and a diminution in errors within the low-concentration section when deploying AEM. However, for the Sulfur wavelength of 921.3nm, there remains a need to augment the sensitivity of the LIBS signal within the low-concentration section in future studies. The findings underscore the potential of employing AEM and LIBS for precise analysis of chloride and sulfate ion penetration into mortar sections. This strategy can aid in bolstering assessment precision and mitigating errors, particularly in regions with low concentrations. It is recommended to further research and develop methods to amplify the sensitivity of the LIBS signal for sulfur detection in low-concentration sections. In sum, the study accentuates the significance of employing advanced techniques like AEM and LIBS for efficacious and precise analysis in the domain of mortar section assessment.

• Journal of the Korean Society of Radiology
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• v.17 no.2
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• pp.243-248
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• 2023

This study aims to analyze the secondary carcinogenesis rate caused by exposure of organs at risk of damage using a glass dosimeter during radiosurgery in vestibular schwannoma disease. Using a pediatric phantom of human tissue equivalent material, the volume of the tumor was set to a total of three volumes: 0.506 cm³, 1.008 cm³, and 2.032 cm³, and a radiosurgery plan was established with an average dose of 18.4 ± 3.4 Gy. After mounting the human body phantom on the table of surgical equipment, glass dosimeters were placed on the right eye, left eye, thyroid gland, thymus, right lung, and left lung to measure the exposure dose, respectively. In this study, the incidence of secondary cancer due to exposure to damaged organs during gamma knife radiosurgery in vestibular schwannoma disease with the largest tumor volume of 2.032 cm³ was measured with a glass dosimeter. This study studies the risk of secondary radiation exposure dose that can occur during stereotactic radiosurgery, and it is considered that it will be used as basic data in the field of radiation damage related to the stochastic effect of radiation in the future.

• The Journal of Engineering Geology
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• v.32 no.1
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• pp.59-72
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• 2022

This study employed a 3-D numerical analysis based on the distinct element method to estimate the strength and deformability of a Cretaceous biotite granitic rock mass at Gijang, Busan, Korea. A workflow was proposed to evaluate the scale effect and the representative elementary volume (REV) of mechanical properties for fractured rock masses. Directional strength and deformability parameters such as block strength, deformation modulus, shear modulus, and bulk modulus were estimated for a discrete fracture network (DFN) in a cubic block the size of the REV. The size of the mechanical REV for fractured rock masses in the study area was determined to be a 15 m cube. The mean block strength and mean deformation modulus of the DFN cube block were found to be 52.8% and 57.7% of the intact rock's strength and Young's modulus, respectively. A constitutive model was derived for the study area that describes the linear-elastic and orthotropic mechanical behavior of the rock mass. The model is expected to help evaluate the stability of tunnels and underground spaces through equivalent continuum analysis.

• The Journal of Korean Institute of Next Generation Computing
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• v.13 no.3
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• pp.15-25
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• 2017

As the value and importance of softwares are growing up, software theft and piracy become a much larger problem. To tackle this problem, it is highly required to provide an accurate method for detecting software theft and piracy. Especially, while software theft is relatively easy in the case of Android applications (apps), screening illegal apps has not been properly performed in Android markets. In this paper, we propose a method to effectively measure the similarity between Android apps for detecting software theft at the executable file level. Our proposed method extracts method reference frequency and manifest information through static analysis of executable Android apps as the main features for similarity measurement. Each app is represented as an n-dimensional vectors with the features, and then cosine similarity is utilized as the similarity measure. We demonstrate the effectiveness of our proposed method by evaluating its accuracy in comparison with typical source code-based similarity measurement methods. As a result of the experiments for the Android apps whose source file and executable file are available side by side, we found that our similarity degree measured at the executable file level is almost equivalent to the existing well-known similarity degree measured at the source file level.

• Journal of Industrial Convergence
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• v.21 no.7
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• pp.93-104
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• 2023

This study was designed to evaluate effects of Patients Empowerment Program for Schizophrenia (PEPS) on Empowerment, Internalized Stigma, Self-esteem, and Quality of Life, in people with chronic schizophrenia living in a rural community. A non-equivalent control group repeated measures design was used. Participants were 22 persons with chronic schizophrenia enrolled from O Province Mental Health Welfare Center, South Korea. (experimental group= 10, control group = 12). The PEPS was administered to the experimental group, consisting of 16 sessions delivered twice a week for 8 weeks. SPSS/WIN 26.0 was used to analyze the collected data using χ²-test, independent t-test, Fisher's exact test, and repeated measures ANOVA. Upon completion of PEPS, the experimental group showed a significantly increased in Self-esteem (F=6.09, p=.005) and Quality of Life (F=3.37, p=.044) as compared to the control group. However, there was no significant difference between the two groups between Empowerment and Internalized Stigma. The results suggest that the PEPS may be an effective intervention for improving Self-esteem and Quality of Life.

• Journal of the Korean Institute of Rural Architecture
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• v.24 no.4
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• pp.85-95
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• 2022

This study is about the story of 'Saemi', existing in the Sacheon Alluvial fan area. Saemi is a local word for Dumbeong, which is the traditional water irrigation facilities in this area that could be formed according to the geographical characteristics of a Alluvial fan site. In the meantime, although Saemi has been an important source of water, related research has been mainly done from an ecological point of view. Accordingly, the researcher paid attention to the functional aspects of Saemi itself, grasped its location, distribution status, and usage including the construction method, and considered its intrinsic value through classification and characteristic analysis of Saemi. As a result of five field surveys from September 2021 to October 2022, 129 Saemies remained in the Sacheon alluvial fan area. According to the structure and shape, Saemi could be divided into basic type, complex type, and buried type. The basic type was subdivided into bucket-type and stairs-type along with the complex type, and the buried type was subdivided into all buried-type and some buried-type. Saemies were mainly distributed at the distal end of the Sacheon alluvial fan site, individual Saemies were built on farmland, and common Saemies were usually built along roadsides adjacent to villages. The reason why the Saemies are concentrated at the distal end is the geographical characteristics of the alluvial fan where the water underflows. Saemi was an important multifunctional water supply source equivalent to the main water source for people at the distal end of the pond who did not receive a stable supply of water from the reservoir. Saemi was at the center of the underground water irrigation network agricultural system in the Sacheon alluvial fan area according to the principles of 'bbaeim(drop out)' and 'gaepim(pooling)' It has provided a foundation for establishing itself as an appropriate technology in this area. Such Saemi contributed to the rural landscape and agricultural biodiversity through its own system and served as a public interest function. It is necessary to know, conserve, manage, and continuously utilize the value of this Saemi as an agricultural heritage.